HPRA Drug Safety Newsletter Edition 95

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 The latest edition of the HPRA Drug Safety Newsletter (DSN) includes important updates to support the safe and appropriate use of the following medicines:

Methotrexate – New measures to avoid dosing errors

SGLT2 inhibitors – Updated advice on monitoring ketone bodies in patients hospitalised for major surgical procedures or acute serious medical illnesses

Ingenol mebutate (Picato) – Use with caution in patients with a history of skin cancer

Fingolimod (Gilenya) – Contraindication in pregnant women and in women of child bearing potential not using effective contraception

Levothyroxine – Close monitoring recommended in the event of a brand change

Parenteral nutrition products for neonates and children below 2 years of age – Protect from light until administration is completed


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