HPRA Drug Safety Newsletter Edition 77

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 The latest edition of the HPRA Drug Safety Newsletter (DSN) includes updates to support the safe and appropriate ise of the following medicines:

  • Direct-Acting antivirals for hepatitis C : Advice on interaction potential with warfarin and other vitamin K antagonists.
  • Advice on potential interaction between cobicistat-containing products and corticosteroids primarlily metabolised by CYP3A : Risk of adrenal suppression.
  • Adverse reaction reporting during 2015.

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