My HPRA: Register

Medicinal Product Shortages

The HPRA is responsible for co-ordinating the management of shortages of human medicines on the Irish market. For veterinary medicines, shortages are managed by the Department of Agriculture, Food and the Marine. 

The HPRA works with a variety of stakeholders including manufacturers, wholesale distributors, marketing authorisation holders, healthcare professionals, the Health Service Executive, patients and representative groups to respond to potential shortages and reduce the impact of shortages on patients.

The definition of a shortage is when the supply of a medicinal product is inadequate to meet the needs of the patient. 

The HPRA, in collaboration with stakeholders, has published a framework for a multi-stakeholder approach to handling shortages of human medicinal products. The aim of the framework is to help prevent shortages from occurring and to reduce the impact of shortages on patients by co-ordinating the management of potential or actual shortages as they arise. You can see the shortages case study on Adrenaline auto-injectors (AAIs) as an example of how the framework operates in practice. 


Information on reporting shortages for:

Marketing Authorisation Holders

Please complete the Notification of medicinal product shortage from marketing authorisation holder form and return to  shortages@hpra.ie and to the HSE Corporate Pharmaceutical Unit.

Wholesale Distributors and Manufacturers

Please complete the Report of medicinal product shortage affecting the Irish market from wholesale distributors and manufacturers form and return this form to  shortages@hpra.ie.

Patients and Healthcare Professionals

Please complete the Report of medicinal product shortage affecting the Irish market from patients and healthcare professionals form and return to  shortages@hpra.ie. When completing this form, please include as much information as possible.

Veterinary Medicines

Please contact the Department of Agriculture, Food and the Marine.

 

Current and resolved shortages

The HPRA publishes a list of shortages currently affecting the Irish market that have been notified to us and that may have a medium or high impact on patients. This list can be found below. More information on the impact level can be found in the framework for a multi-stakeholder approach to handling shortages of human medicinal products.

The HPRA maintains a consolidated list of resolved shortages for a period of six months. Details of shortages that have been resolved in the last six months can be found here.


RoActemra supply disruptions

The marketing authorisation holder (MAH; Roche) notified the HPRA of a shortage of tocilizumab-containing medicines caused by increased global demand for the active ingredient. Tocilizumab products in Ireland are marketed under the brand name RoActemra. The shortage is not specific to the Irish market and is global in nature, affecting multiple countries.

Due to the increased global demand, the company has advised of intermittent supply of RoActemra medicines during September. Further deliveries of RoActemra pre-filled pen and pre-filled syringe products are expected in October and November. Please see Roche’s communication for additional details (HCP letter 1, HCP letter 2).

The HPRA is in regular contact with the company concerning the restoration of supply to patients in Ireland. The HPRA Shortages webpage is updated with the most current information on expected resupply dates.


Please use search function below to find relevant product or active ingredient

 
Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abstral 100mcg Sublingual Tablets

PA2288/004/002
  Fentanyl  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
3rd September 2021 

Expected return date: 
Mid October 2021 		 Last updated: 
3rd September 2021
Abstral 200mcg Sublingual Tablets

PA2288/004/003
 Fentanyl Manufacturing delay 

(multiple countries affected		 Date of shortage:
15th August 2021

Return date: 
Unknown at present 		 Last updated: 
11th August 2021
Abstral 600mcg Sublingual Tablets

PA2288/004/006
 Fentanyl   Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
2nd September 2021 

Expected return date: 
Late October 2021 		 Last updated: 
3rd September 2021
Abstral 700mcg Sublingual Tablets

PA2288/004/007
 Fentanyl Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
2nd September 2021

Expected return date: 
Mid November 2021		 Last updated: 
3rd September 2021
Amitriptyline 25mg Film Coated Tablets

PA0126/041/001
 Amitriptyline
 API unavailability Date of shortage: 
2nd September 2021 

Expected return date: 
Late October 2021		 Last updated: 
7th September 2021 

HCP letter
Aprovel 150mg Tablets

EU/1/97/046/022
 Irbesartan Quality issue 

Multiple countries impacted  		 Date of shortage: 
22nd July 2021

Expected return date: 
Late October 2021		 Last updated: 
29th July 2021
Astilin 10mg Tablets

PA23163/001/001
 Amitriptyline  Awaiting update Date of shortage: 
27th August 2021

Expected return date: 
4th October 2021		 Last updated: 
15th September 2021

HCP letter
Ativan 4mg/ml Solution for Injection

PA0822/090/002 		 Lorazepam  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2020

Expected return date:
Unknown at present		 Last updated:
14th May 2021 
 
HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
2022		 Last updated:
3rd February 2021
Bendroflumethiazide 2.5mg Tablets

PA22749/021/001
 Bendroflumethiazide
  Regulatory issue Date of shortage:
3rd September 2021

Expected return date: 
End September 2021		 Last updated: 
2nd September 2021
Beromun 1mg Powder for Solution for Infusion

EU/1/99/097/001 		 Tasonermin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
December 2020

Expected return date:
November 2021		 Last updated:
1st June 2021
Betnesol 0.1% w/v Eye, Ear and Nasal Drops

PA1638/001/001
 Betamethasone 
 Shipping delay Date of shortage: 
Mid August 2021

Expected return date: 
Week commencing 20th September 2021 		 Last updated: 
15th September 2021
Calcium Acetate 500mg Tablets

PA0281/063/001
 Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
October 2021 		 Last updated: 
26th July 2021
Catapres Tablets 100mcg

PA2256/003/001
  Clonidine Manufacturing delays

(multiple countries affected)		 Date of shortage: 
25th July 2021

Expected return date: 
25th October 2021		 Last updated: 
21st June 2021 
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Chlorpromazine Elixir BP 25mg/5ml Oral Solution

PA0281/124/001 		 Chlorpromazine hydrochloride  Manufacturing delays  Date of shortage:
End of February 2021

Expected return date:
September 2021		 Last updated:
22nd June 2021
 
HCP letter
 
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion

PA1457/001/002		 Amoxicillin & clavalunic acid Unexpected increase in demand Date of shortage:
5th February 2020

Expected return date:
October 2021
 Last updated:
15th June 2021
Creon for Children 5000 Gastro Resistant Granules

PA2010/008/004
 Pancreas powder
 API unavailability   Date of shortage: 
Late September 2021

Expected return date: 
October 2021		  Last updated: 
15th September 2021
Dalacin 2% Vaginal Cream 

PA0822/119/002
  Clindamycin  Shipping delay   Date of shortage: 
Week commencing 6th August 2021

Expected return date: 
Awaiting update		 Last updated:
17th September
Depo-Provera 150mg/ml Suspension for Injection 

PA0822/124/001
 Medroxyprogestrone acetate
 Regulatory issue Date of shortage: 
31st August 2021 

Expected return date: 
End September 2021
 Last updated: 10th September 2021
Desloratadine 5mg Film Coated Tablets 

PA2315/016/001
 Desloratadine Manufacturing delay  Date of shortage: 
Week commencing 21st June 2021

Expected return date: 
Week commencing 27th September 2021		 Last updated: 
10th September 2021
Desmopressin 100mcg/ml Nasal Drop Solution

PA1009/001/001 		 Desmopressin  Manufacturing delays due to quality issue

(multiple countries affected) 		 Date of shortage:
Mid December 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Dioralyte Blackcurrant Powder for Oral Solution (20 pack)

PA0540/098/001
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate  Unexpected increase in demand  Date of shortage: 
17th September 2021

Expected return date: 
24th September 2021		  Last updated: 
14th September 2021
Dioralyte Citrus Powder for Oral Solution
(20 pack)

PA0540/098/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
Early October 2021
  Last updated: 
14th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution
(6 pack)

PA0540/194/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
Early October 2021
  Last updated: 
14th September 2021
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005		 Phenytoin Manufacturing delays

(multiple countries affected)		 Date of shortage:
Early November 2019

Expected return date:
Unknown at present		 Last updated:
4th June 2020
 
HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion

PA1852/002/001 		 Esomeprazole  Unavailability of API  Date of shortage:
Early October 2020

Expected return date:
Late September 2021		 Last updated:
23rd August 2021
Fludarabine phosphate 25mg/ml Solution for Injection or Infusion

PA2315/035/001 		 Fludarabine phosphate  Unavailability of API

(multiple countries affected) 		 Date of shortage:
Early November 2020

Expected return date:
Awaiting update		 Last updated:
8th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection

PA0822/198/002
 Folinic Acid  Unexpected increase in demand Date of shortage: 
20th September 2021

Expected return date: 
Unknown at present  		 Last updated:
16th September 2021 
Geodon 80mg Hard Capsules

PA23055/015/004
 Ziprasidone  Unexpected increase in demand Date of shortage: 
31st August 2021

Expected return date: 
21st October 2021		 Last updated: 
8th September 2021
Gentamicin 40 mg/ml Injection, vials

PA0822/203/001
 Gentamicin
 Manufacturing delays

(multiple countries affected)		 Date of shortage:
9th December 2019

Expected return date:
Unknown at present
 Last updated:
11th February 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension

PA1142/014/001
 Gentamicin & Hydrocortisone Unavailability of API 

(multiple countries affected)		 Date of shortage: 
23rd August 2021

Expected return date:
Late November 2021		 Last updated: 
9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
Unknown at present 		 Last updated:
1st July 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
Unknown at present 		 Last updated:
1st July 2021 
Innohep 4,500 IU, solution for injection

PA0046/060/007
 Tinzaparin sodium  Manufacturing delay Date of shortage: 
18th August 2021

Expected return date: 
Late September 2021		 Last updated: 
31st August 2021 

HCP letter
Innohep 8,000 IU in 0.4 ml, Solution for Injection

PA0046/060/012
 Tinzaparin sodium
 Manufacturing delays Date of shortage: 
24th August 2021

Expected return date: 
Late September 2021		 Last updated: 
31st August 2021

HCP letter
Instanyl 50mcg Nasal Spray 

EU/1/09/531/010-013
 Fentanyl  Quality issue 
(multiple countries affected)		 Date of shortage: 
1st August 2021 

Expected return date: 
February 2022
 Last updated: 
20th August 2021
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated: 
20th August 2021
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated:
20th August 2021
Integrilin 0.75mg/ml Solution for infusion

EU/1/99/109/001
 Eptifibatide  Unexpected increase in demand

(multiple countries affected) 		 Date of shortage: 
24th September 2021

Expected return date: 
11th October 2021		 Last updated:
10th September 2021

HCP letter
Integrilin 2mg/ml Solution for Injection

EU/1/99/109/002
 Eptifibatide
 Unexpected increase in demand 

(multiple countries affected) 		 Date of shortage: 
9th August 2021

Expected return date:  
4th October 2021		 Last updated: 
5th August 2021

HCP letter
Lamictal 2mg Chewable/Dispersible Tablets

PA1077/061/005
 Lamotrigine
 Unexpected increase in demand Date of shortage: 
15th September 2021

Expected return date: 
28th September 2021 		 Last updated: 
17th September 2021 
Letrozole Teva 2.5 mg Film Coated Tablets

PA0749/085/001
 Letrozole  API unavailability 

(multiple countries affected) 		 Date of shortage: 
Week commencing 9th August 2021

Expected return date: 
Week commencing 27th September 2021 		 Last updated: 
4th August 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet

PA0711/051/002 		 Lisinopril & Hydrochlorothiazide  Manufacturing delays  Date of shortage:
8th September 2020

Expected return date:
October 2021		 Last updated:1
22nd July 2021
Losartan 50mg Tablet 

PA2315/059/002 		 Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
Unknown at present 		 Last updated:
13th April 2021
Losartan 100mg Tablet

PA2315/059/003 		 Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
13th April 2021
Low Centyl K 1.25mg/573mg Modified Release Tablet

PA22650/002/001 		 Bendroflumethiazide & Potassium chloride  Unavailability of API

(multiple countries affected) 		 Date of shortage:
February 2021

Expected return date:
24th September 2021		 Last updated:
21st June 2021

HCP letter
Marcain 0.25% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/001
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
6th October 2021
 Last updated: 
6th August 2021 
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
 Bupivacaine & adrenaline
 Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
Week commencing 23rd August 2021

Return date: 
Unknown at present		 Last updated: 
9th August 2021
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Metaraminol 10mg/ml Solution for Injection or Infusion 

PA22893/001/001		 Metaraminol  Awaiting update Date of shortage: 
Early April 2021 

Expected return date:
Awaiting update		 Last updated: 
30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution

PA23081/008/001
 Metformin  Regulatory Issue Date of shortage: 
13th August 2021

Expected return date: 
Unknown at present		 Last updated: 
10th August 2021
Methylthioninium chloride 5mg/ml Solution for Injection

EU/1/11/682/001 		 Methylthioninium chloride  Manufacturing delays  Date of shortage:
26th March 2021

Expected return date:
Unknown at present 		 Last updated:
23rd March 2021 
Molipaxin 150mg Film Coated Tablets

PA0540/056/004
 Trazodone Manufacturing delays Date of shortage: 
10th September 2021

Expected return date: 
4th October 2021		 Last updated: 
8th September 2021 
MST Continus 5mg Prolonged Release Tablets

PA1688/004/001
 Morphine  Manufacturing delays Date of shortage: 
17th September 2021

Expected return date: 
Unknown at present 		 Last updated: 
13th September 2021
MST Continus 10mg Prolonged Release Tablets

PA1688/004/002
Morphine		 Manufacturing delays  Date of shortage: 
17th September 2021

Expected return date: 
Unknown at present 
Last updated: 
13th September 2021
Noriday 350mcg Tablets

PA0822/131/001
 Norethisterone Manufacturing delays Date of shortage: 
Week commencing 6th September 2021

Expected return date: 
27th September 2021		 Last updated: 
15th September 2021

HCP letter
Palexia 4mg/ml Oral Solution

PA2242/012/010 		 Tapentadol hydrochloride  Quality issue

(multiple countries affected) 		 Date of shortage:
15th February 2021

Expected return date:
Unknown at present 		 Last updated: 
22nd February 2021
Paralief 500mg Tablets 

24 pack only

PA0126/020/001
 Paracetamol API unavailability  Date of shortage: 
Week commencing 23rd August 2021

Expected return date: 
27th September 2021
 Last updated: 
18th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w

PA0278/017/002
 Hydrocortisone & Lidocaine Hydrochloride  Manufacturing delays  Date of shortage:
February 2021

Expected return date:
January 2022		 Last updated: 
8th April 2021
Phyllocontin Continus 225mg Prolonged Release Tablets

PA1688/008/001
 Aminophylline  Manufacturing delays  Date of shortage: 
20th August 2021

Expected return date: 
20th September 2021		 Last updated: 
15th September 2021
Pregabalin Accord 200mg Hard Capsule

EU/1/15/1027/060 		 Pregabalin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
End of December 2020

Expected return date:
Week commencing 27th September 2021		 Last updated:
10th September 2021
Questran 4g Powder for Oral Suspension

PA2239/005/001 		 Colestyramine  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2019

Expected return date:
January 2022		 Last updated:
30th March 2021 
Rifater 50mg/300mg/120mg Tablets

PA0822/143/002
 Isoniazid & Pyrazinamide & Rifampicin Quality issue

(multiple countries impacted)		 Date of shortage: 
23rd July 2021

Expected return date: 
Mid-late October 2021		 Last updated:
9th September 2021

AMRIC guidance V3
RoActemra 162mg Solution for Injection in Pre Filled Syringe

EU/1/08/492/007
  Tocilizumab  API shortage 

(multiple countries affected)		 Date of shortage: 
7th September 2021

Expected return date: 
Awaiting update		 Last updated: 
13th September 2021

HCP letter 1 
HCP letter 2 

HSE Advisory Statement
RoActemra 162mg Solution for injection in Pre-Filled Pen

EU/1/08/492/009-10
 Tocilizumab  API shortage 

(multiple countries affected)		 Date of shortage: 
2nd September 2021

Expected return date: 
Awaiting update
 Last updated: 
10th September 2021

HCP letter 1 
HCP letter 2 

HSE Advisory Statement
RoActemra 20mg/ml Concentrate for Solution for Infusion

EU/1/08/492/001-006
 Tocilizumab
 API unavailability 

(multiple countries impacted)		 Date of shortage: 
3rd September

Expected return date: 
December 2021 		 Last updated: 
3rd September  2021

HCP letter 1 
HCP letter 2 

HSE Advisory Statement
Rosuvastatin 5mg Film Coated Tablets

PA2315/068/001
 Rosuvastatin Quality issue  Date of shortage:
27th August 2021

Expected return date: 
Q2 2022		  Last updated: 
30th August 2021
Rosuvastatin 10mg Film Coated Tablets

PA2315/068/002
 Rosuvastatin  Quality issue Date of shortage: 
27th August 2021 

Expected return date: 
Q2 2022 		 Last updated: 
30th August 2021 
Sirdupla 25mcg/125mcg Per Metered Dose Pressurised Inhalation, Suspension 

PA0577/201/001
 Salmeterol & Fluticasone Manufacturing delays Date of shortage: 
8th February 2021

Expected return date: 
Awaiting update		 Last updated: 
31st August 2021
Sotoger 80mg Tablets

PA0577/021/001
 Sotalol  Manufacturing delays 
 Date of shortage: 
Mid September 2021

Expected return date: 
Unknown at present  		 Last updated: 
10th September 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
October 2021		 Last updated:
10th August 2021
Stesolid rectal solution 10mg

PA2315/137/002
  Diazepam Manufacturing delays  Date of shortage: 
Week commencing 19th July 2021. 

Expected return date: 
November 2021		 Last updated: 
21st July 2021
Teicoplanin 200 mg Powder and Solvent for Solution for Injection/Infusion or Oral Solution

PA1122/009/001
  Teicoplanin Manufacturing delay Date of shortage: 
Week commencing 12th July 2021

Expected return date: 
End September 2012		 Last updated: 
6th September 2021
Telmisartan Rowa 40mg Tablets

PA0074/078/002
 Telmisartan  Unexpected increase in demand  Date of shortage: 
7th September 2021

Expected return date: 
October 2021		  Last updated: 
14th September 2021
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
 Alendronic acid API unavailability  Date of shortage: 
6th September 2021 

Expected return date: 
Late November 2021 		 Last updated: 
23rd August 2021 
Tracrium 10mg/ml, Solution for Injection or Infusion

(50mg/5ml ampoule)

PA1691/029/001
  Atracurium Unexpected increase in demand Date of shortage:
15th August 2021

Expected return date: 
22nd September 2021		 Last updated: 
8th September 2021
Tracrium 10 mg/ml, Solution for injection or infusion

(25ml ampoule)

PA1691/029/002
 Atracurium  Unexpected increase in demand Date of shortage: 
1st October 2021

Expected return date: 
20th November 2021 		  Last updated: 
17th September 2021
Trandate 100mg Film Coated Tablet

PA1638/006/002 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
End September 2021		 Last updated:
3rd September 2021
Trandate 200mg Film Coated Tablet

PA1638/006/003 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
End September 2021		 Last updated:
3rd September 2021
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment

PA22650/004/001
 Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride  Regulatory issue Date of shortage: 
Late September 2021

Expected return date: 
Late December 2021
 Last updated: 
15th September 2021
Visudyne 15mg Powder for Solution for Infusion

EU/1/00/140/001
 Verteporfin  Manufacturing delay  Date of shortage: 
May 2021

Expected return date: 
January 2022		 Last updated: 
28th July 2021

HCP letter
Zerbaxa 1g/0.5g Powder for Concentrate for Solution for Infusion

EU/1/15/1032/001 		 Ceftolozone & Tazobactam  Quality issue

(multiple countries affected) 		 Date of shortage:
18th December 2020

Expected return date:
Unknown at present 		 Last updated:
4th March 2021 
Xomolix 2.5mg/ml Solution for Injection

PA2288/003/002
 Droperidol  Quality issue

(multiple countries affected)		 Date of shortage: 
29th May 2021

Expected return date: 
Unknown at present  		 Last updated: 
2nd July 2021
Xylocaine 2% with Adrenaline (Epinephrine) (1:200,000) Solution for Injection

PA1691/027/001
 Lidocaine & adrenaline  Manufacturing delays

(multiple countries affected)		 Date of shortage: 
1st August 2021

Expected return date: 
10th October 2021		 Last updated: 
6th August 2021
Zofran 4 mg/5 ml syrup
 Ondansetron Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
8th August 2021

Expected return date: 
Awaiting update		 Last updated: 
16th September 2021

Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL



Date of shortage: 
2nd July 2021

Expected return date: 
Unknown at present  
Date of shortage: 
2nd July 2021

Expected return date: 
Unknown at present  


Contact us:

Medicinal Product Shortages Unit
Health Products Regulatory Authority 
Kevin O’Malley House
Earlsfort Terrace,
Dublin 2
Tel: +353 1 676 4971
Fax: +353 1 676 7836
shortages@hpra.ie