Medicinal Product Shortages

The HPRA is responsible for co-ordinating the management of shortages of human medicines on the Irish market. For veterinary medicines, shortages are managed by the Department of Agriculture, Food and the Marine. 

The HPRA works with a variety of stakeholders including manufacturers, wholesale distributors, marketing authorisation holders, healthcare professionals, the Health Service Executive, patients and representative groups to respond to potential shortages and reduce the impact of shortages on patients.

The definition of a shortage is when the supply of a medicinal product is inadequate to meet the needs of the patient. 

The HPRA, in collaboration with stakeholders, has published a framework for a multi-stakeholder approach to handling shortages of human medicinal products. The aim of the framework is to help prevent shortages from occurring and to reduce the impact of shortages on patients by co-ordinating the management of potential or actual shortages as they arise. You can see the shortages case study on Adrenaline auto-injectors (AAIs) as an example of how the framework operates in practice. 


Information on reporting shortages for:

Wholesale Distributors and Manufacturers

Patients and Healthcare Professionals

Please complete the  Report of a Medicinal Product Shortage from Patients and Healthcare Professionals form and return to  shortages@hpra.ie. When completing this form, please include as much information as possible.

Veterinary Medicines

Current and resolved shortages

The HPRA publishes a list of shortages currently affecting the Irish market that have been notified to us and that may have a medium or high impact on patients. This list can be found below. More information on the impact level can be found in the framework for a multi-stakeholder approach to handling shortages of human medicinal products.

The HPRA maintains a consolidated list of resolved shortages for a period of six months. Details of shortages that have been resolved in the last six months can be found here.
 

Hormone replacement therapy (HRT) shortages

HRT shortages have impacted multiple countries over the past year and are not restricted to Ireland. While there are shortages of some specific brands, alternatives are available to meet patient need. The suppliers have stated that the causes of the shortages relate to both active substance availability and manufacturing delays. It is not related to Brexit. The HPRA continues to be in frequent contact with the suppliers to maintain efforts to expedite re-supply as soon as possible. The HPRA website will be will be kept up to date as additional information becomes available.

 

If a patient has any concerns about their medicine, the HPRA advises that they should discuss their treatment a doctor or pharmacist.


Please use search function below to find relevant product or active ingredient

 
Product name Active ingredient Reason for shortage Date of shortage
Additional information
Adalat LA 20mg Prolonged Release Tablet

PA1410/025/005
Nifedipine  Manufacturing delays

(multiple countries affected)
Date of shortage:
November 2017
 
Expected return date:
Not before 2021
Last updated:
29th November 2019
 
Adalat LA 30mg Prolonged Release Tablet

PA1410/025/006
Nifedipine  Manufacturing delays

(multiple countries affected)
Date of shortage:
24th June 2018

Expected return date:
Not before 2021
Last updated:
29th November 2019 
 
Adalat LA 60mg Prolonged Release Tablet

PA1410/025/007 
Nifedipine Manufacturing delays

(multiple countries affected)
Date of shortage:
September 2018

Expected return date:
Not before 2021
Last updated:
29th November 2019
 
Alendronate/Colecalciferol Teva 70mg/5600IU Tablet

PA0749/196/002 
Alendronate & Colecalciferol  Manufacturing delays  Date of shortage:
January 2019

Expected return date:
End of July 2020 
Last updated:
17th June 2020 
Amisulpride 50mg Tablet

PA0577/182/001 
Amisulpride  Manufacturing delays  Date of shortage:
July 2019

Expected return date:
August 2020
Last updated:
26th June 2020 
Amoxil Vials 500mg Powder for Solution for Injection or Infusion

PA1077/033/004 
Amoxicillin  Unavailability of API

(multiple countries affected) 
Date of shortage:
25th February 2020

Expected return date:
Early July 2020 
Last updated:
1st May 2020 
Areloger 15mg Film Coated Tablet

PA0577/057/002 
Meloxicam  Manufacturing delays  Date of shortage:
Early August 2019

Expected return date:
August 2020
Last updated:
18th February 2020 
Arthrotec 50 Modified Release Tablet

PA0822/112/001 
Diclofenac & Misoprostol  Manufactuirng delays  Date of shortage:
20th April 2020

Expected return date:
Early August 2020 
Last updated:
26th June 2020 
             
HCP Letter
Atenomel 50mg Tablet

PA0126/069/001 
Atenolol  Unexpected increase in demand  Date of shortage:
End of April 2020

Expected return date:
End of July 2020 
Last updated:
30th June 2020 
Atorvastatin 80mg Tablet

PA0126/271/004
Atorvastatin Manufacturing delays Date of shortage:
11th May 2020

Expected return date:
5th August 2020
Last updated:
13th May 2020 
Axsain 0.075% w/w Cream

PA0827/004/001 
Capsaicin  Manufacturing delays 

(multiple countries affected)
Date of shortage:
Mid June 2019

Expected return date:
End of July 2020
Last updated:
17th June 2020 
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 
Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 
Date of shortage:
1st October 2019

Expected return date:
Unknown at present 
Last updated:
7th November 2019 
Bendamustine 100mg Powder for Solution for Infusion

PA1380/163/002 
Bendamustine  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid May 2020

Expected return date:
Mid July 2020 
Last updated:
4th June 2020 
Blopress 16mg Tablet

PA2229/001/004
 Candesartan Manufacturing delays

(multiple countries affected)
Date of shortage:
11th May 2020

Expected return date:
Awaiting update
Last updated:
2nd July 2020 
Brufen 800mg Prolonged Release Tablet

PA2010/002/007 
Ibuprofen  Increased demand  Date of shortage:
11th June 2020

Expected return date:
11th July 2020 
Last updated:
29th June 2020 
Candist 8mg Tablet

PA0126/206/002 
Candesartan  Unexpected increase in demand

 
Date of shortage:
End of April 2020

Expected return date:
Mid August 2020
Last updated:
24th April 2020 
Canesten Duopack - 100mg Pessary & 1% w/w Cream

PA1410/039/005 
Clotrimazole  Manufacturing delays

(multiple countries affected) 
Date of shortage:
February 2018

Expected return date:
August 2020 
Last updated:
7th May 2020
             
HCP Letter
Canesten 200mg Pessary

PA1410/039/008 
Clotrimazole  Manufacturing delay

(multiple countries affected) 
Date of shortage:
February 2018

Expected return date:
August 2020
Last updated:
7th May 2020
             
HCP Letter
Canesten 500mg Pessary

PA1410/039/009 
Clotrimazole  Manufacturing delay

(multiple countries affected) 
Date of shortage:
January 2018

Expected return date:
August 2020
Last updated:
7th May 2020
                         
HCP Letter
Catasart 8mg Tablet

PA0711/134/002 
Candesartan  Manufcaturing delays  Date of shortage:
20th May 2020

Expected return date:
End of August 2020
Last updated:
16th June 2020 
Celecoxib 100mg Capsule

PA0711/241/001 
Celecoxib  Manufacturing delays  Date of shortage:
Mid May 2020

Expected return date:
13th August 2020 
Last updated:
16th June 2020 
Celecoxib 200mg Capsule

PA2315/228/002 
Celecoxib  Manufacturing delays  Date of shortage:
February 2020

Expected return date:
Awaiting update 
Last updated:
16th June 2020 
Celecoxib 200mg Capsule

PA0711/241/002 
Celecoxib  Manufacturing delays  Date of shortage:
Mid June 2020

Expected return date:
Early July 2020 
Last updated:
26th June 2020 
Cimeldine 400mg Film Coated Tablet

PA0126/077/002 
Cimetidine  API delay  Date of shortage:
9th December 2019

Expected return date:
6th July 2020 
Last updated:
24th April 2020 
Ciprofloxacin Teva 250mg Film Coated Tablet


PA0749/031/002 
Ciprofloxacin  Manufacturing delays  Date of shortage:
Early September 2019

Expected return date:
August 2020
Last updated:
17th June 2020
Clonfolic 0.4mg Tablet

PA0126/095/001 
Folic acid  Manufacturing delays  Date of shortage:
Early June 2020

Expected return date:
23rd July 2020 
Last updated:
11th June 2020 
Co-Amoxiclav 1000mg/200mg Powder for solution for injection/infusion

PA1339/005/002
Amoxicillin & clavalunic acid Unexpected increased demand Date of shortage:
5th February 2020

Expected return date:
Unknown at present
Last updated:
4th June 2020 
Deslor 0.5mg/ml Oral Solution

PA0711/202/002 
Desloratidine  Manufacturing delays  Date of shortage:
Mid June 2020

Expected return date:
Mid July 2020 
Last updated:
26th June 2020 
Diabrezide 80mg Tablet

PA0925/001/001 
Gliclazide  Manufacturing delays  Date of shortage:
End of May 2020

Expected return date:
Mid July 2020
Last updated:
11th June 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 
Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present 
Last updated:
1st May 2020 
Efexor 37.5mg prolonged release capsules, hard

PA0822/072/001
Venlafaxine hydrochloride Manufacturing delays Date of shortage:
27th April 2020

Expected return date:
Mid July 2020
Last updated:
16th June 2020 
Emazole 40mg Gastro-Resistant Tablet

PA0711/158/002 
Esomeprazole  Manufacturing delays  Date of shortage:
End of May 2020

Expected return date:
Mid July 2020 
Last updated:
5th June 2020 
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 
Adrenaline  Quality issue

(multiple countries affected) 
Date of shortage:
30th September 2019

Expected return date:
Unknown at present 
Last updated:
30th September 2019

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 
Adrenaline  Quality issue

(multiple countries affected) 
Date of shortage:
30th September 2019

Expected return date:
Unknown at present 
Last updated:
30th September 2019

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 
Adrenaline  Quality issue

(multiple countries affected) 
Date of shortage:
30th September 2019

Expected return date:
Unknown at present 
Last updated:
30th September 2019

Alternatives are available 
Enap 10mg Tablet

PA0711/028/002 
Enalapril  Manufacturing delay  Date of shortage:
End of April 2020

Expected return date:
Mid August 2020 
Last updated:
4th June 2020 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005
Phenytoin Manufacturing delays

(multiple countries affected)
Date of shortage:
Early November 2019

Expected return date:
Unknown at present
Last updated:
4th June 2020
 
HCP Letter
Erythrocin 250mg Tablet

PA1142/008/002 
Erythrocin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Early August 2019

Expected return date:
August 2020
Last updated:
27th May 2020 
Erythrocin 500mg Tablet

PA1142/008/003 
Erythrocin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
End of February 2020

Expected return date:
August 2020
Last updated:
27th May 2020 
Erythroped PI SF 125mg/5ml Granules for Oral Suspension

PA1142/006/002 
Erythromycin  Manufacturing delays 

(multiple countries affected)
Date of shortage:
End of June 2019

Expected return date:
August 2020 
Last updated:
27th May 2020 
Erythroped SF 250mg/5ml Granules for Oral Suspension

PA1142/006/001 
Erythromycin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid November 2019

Expected return date:
August 2020
Last updated:
27th May 2020 
Estradot 37.5mcg/day Transdermal Patch

PA0896/010/001 
Estradiol  Manufacturing delays

(multiple countries affected) 
Date of shortage:
End of June 2020

Expected return date:
15th August 2020 
Last updated:
1st July 2020

HCP Letter 
Estradot 75mcg/day Transdermal Patch

PA0896/010/003 
Estradiol  Manufacturing delays

(multiple countries affected) 
Date of shortage:
29th April 2020

Expected return date:
20th July 2020 
Last updated:
1st July 2020 

HCP Letter
Estradot 100mcg/day Transdermal Patch

PA0896/010/004 
Estradiol  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Early June 2020

Expected return date:
15th August 2020 
Last updated:
1st July 2020
 
HCP Letter
Evorel 50mcg Transdermal Patch

PA22668/008/001 
Estradiol  Manufacturing delays

(multiple countries affected) 
Date of shortage:
October 2019

Expected return date:
Mid July 2020 
Last updated:
23rd June 2020
             

 
Evorel Conti 50mcg/170mcg Transdermal Patch

PA22668/009/001 
Estradiol & Norethisterone Manufacturing delays

(multiple countries affected) 
Date of shortage:
Early January 2020

Expected return date:
Mid July 2020 
Last updated:
23rd June 2020
             

 
             
Ezetimibe/Simvastatin Clonmel 10mg/10mg 

PA0126/281/001
Ezetimibe & Simvastatin  Manufacturing delay  Date of shortage:
6th January 2020

Expected return date:
21st July 2020 
Last updated:
24th April 2020
Fludrocortisone 0.1mg Tablet

PA1691/018/001 
Fludrocortisone acetate  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid May 2020

Expected return date:
Awaiting update 
Last updated:
18th June 2020 
Folinic Acid 10mg/ml Solution for Injection

(100mg/10ml presentation only)

PA0822/198/003 
Folinic acid  Manufacturing delays  Date of shortage:
5th July 2019

Expected return date:
July 2020
Last updated:
10th February 2020
Flixotide 0.5mg/2ml Nebules

PA1077/044/016 
Fluticasone  Manufacturing delays

(multiple countries affected) 
Date of shortage:
13th May 2020

Expected return date:
2021 
Last updated:
28th May 2020 
Flucol 150mg Capsule

PA0711/057/003 
Fluconazole  Manufacturing delays  Date of shortage:
10th June 2020

Expected return date:
Mid August 2020 
Last updated:
16th June 2020 
Fluzac 20mg Capsule

PA0711/110/001 
Fluoxetine  Unexpected increase in demand  Date of shortage:
17th April 2020

Expected return date:
July 2020 
Last updated:
23rd June 2020 
Foznol 750mg Chewable Tablet

PA1575/002/003 
Ianthanum carbonate hydrate  Manufacturing delays

(multiple countries affected) 
Date of shortage:
12th June 2020

Expected return date:
20th July 2020 
Last updated:
9th June 2020 
Foznol 1000mg Chewable Tablet

PA1575/002/004 
Ianthanum carbonate hydrate  Manufacturing delays

(multiple countries affected) 
Date of shortage:
12th June 2020

Expected return date:
13th July 2020 
Last updated:
9th June 2020 
Gaviscon Advance Oral Suspension

PA0979/015/001 
Sodium alginate & Potassium hydrogen carbonate  Manufacturing delays  Date of shortage:
June 2020

Expected return date:
27th July 2020 
Last updated:
29th June 2020 
Gaviscon Liquid Peppermint Flavour Oral Suspension

PA0979/015/002 
Sodium bicarbonate; Calcium carbonate & Sodium alginate  Manufacturing delays  Date of shortage:
29th June 2020

Expected return date:
6th July 2020 
Last updated:
29th June 2020 
Gaviscon Oral Suspension

PA0979/015/001 
Sodium bicarbonate; Calcium carbonate & Sodium alginate  Manufacturing delays  Date of shortage:
6th July 2020

Expected return date:
Unknown at present 
Last updated:
2nd July 2020 
Genotropin Miniquick 0.4mg Powder and Solvent for Solution for Injection

PA0822/128/004 
Somatropin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
23rd April 2020

Expected return date:
End of August 2020
Last updated:
2nd July 2020 
Genotropin Miniquick 1.6mg Powder and Solvent for Solution for Injection

PA0822/128/010 
Somatropin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid March 2020

Expected return date:
End of August 2020 
Last updated:
2nd July 2020 
Genotropin Miniquick 1.8mg Powder and Solvent for Solution for Injection

PA0822/128/011 
Somatropin
Manufacturing delays

(multiple countries affected) 
Date of shortage:
10th February 2020

Expected return date:
Week commencing 6th July 2020
Last updated:
2nd July 2020 
Genotropin Miniquick 2mg Powder and Solvent for Solution for Injection

PA0822/128/012 
Somatropin
Manufacturing delays

(multiple countries affected)  
Date of shortage:
6th February 2020

Expected return date:
End of July 2020 
Last updated:
2nd July 2020
Gentamicin 40 mg/ml Injection, vials

PA0822/203/001
Gentamicin
Manufacturing delays

(multiple countries impacted)
Date of shortage:
9th December 2019

Expected return date:
August 2020
Last updated:
10th February 2020
Gerozac 20mg Capsule

PA0577/200/001 
Fluoxetine  Manufacturing delays  Date of shortage:
Early December 2019

Expected return date:
Unknown at present 
Last updated:
26th June 2020 
Gerozac 60mg Capsule

PA0577/071/001 
Fluoxetine  Manufacturing delays  Date of shortage:
Early December 2020

Expected return date:
Unknown at present
Last updated:
26th June 2020 
Gertac 150mg Film Coated Tablet

PA0577/023/001 
Ranitidine  Active substance impurity

(multiple countries affected) 
Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 
Last updated:
22nd October 2019

MMP Guidance for Prescribers 

AHDMP Guidance for Prescribers
Gertac 300mg Film Coated Tablet

PA0577/023/002 
Ranitidine  Active substance impurities

(multiple countries affected) 
Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 
Last updated:
22nd October 2019

MMP Guidance for Prescribers 

AHDMP Guidance for Prescribers
HBVAXPRO 40mcg Suspension for Injection

EU/1/01/183/015 
Hepatitis B  Manufacturing delays

(multiple countries affected) 
Date of shortage:
12th November 2019

Expected return date:
End of 2020 
Last updated:
13th November 2019 
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 
Hydromorphone  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid June 2020

Expected return date:
November 2020 
Last updated:
3rd July 2020 
Hypnovel 10mg/5ml Solution for Injection

PA2239/007/002
Midazolam  Unexpected increase in demand  Date of shortage:
2nd April 2020

Expected return date:
August 2020
Last updated:
21st May 2020 
Hypovase 1mg Tablet

PA0822/195/002 
Prazosin hydrochloride  Manufacturing delay 

(multiple countries affected)
Date of shortage:
Mid June 2019

Expected return date:
Unknown at present
Last updated:
2nd June 2020
Hytrin 2mg Tablet

PA1142/005/002 
Terazosin  Manufacturing delay 

(multiple countries affected)
Date of shortage:
Early June 2020

Expected return date:
7th August 2020 
Last updated:
25th June 2020 
Hytrin 10mg Tablet

PA1142/005/004 
Terazosin  Manufacturing delay 

(multiple countries affected)
Date of shortage:
Early June 2020

Expected return date:
3rd July 2020
Last updated:
25th June 2020 
Imdur 60mg Prolonged Release Tablet

PA2129/001/001 
Isosorbide mononitrate  Manufacturing delays

(multiple countries affected)
Date of shortage:
Mid May 2020

Expected return date:
Early July 2020 
Last updated:
19th May 2020 
Indivina 1mg/2.5mg Tablet

PA1327/005/001 
Medroxyprogestrone & Estradiol  Manufacturing delays  Date of shortage:
February 2020

Expected return date:
Awaiting update 
Last updated:
2nd June 2020 
Indivina 2mg/5mg Tablet

PA1327/005/003 
Medroxyprogestrone & Estradiol  Manufacturing delays  Date of shortage:
February 2020

Expected return date:
Awaiting update
Last updated:
2nd June 2020 
Irprestan 150mg Film Coated Tablet

PA1380/021/002 
Irprestan  Active substance impurity

(multiple countries affected) 
Date of shortage:
February 2019

Expected return date:
October 2020
Last updated:
3rd July 2019 
Isoptin 40mg Film Coated Tablet

PA2010/003/001 
Verapamil  Manufacturing delays  Date of shortage:
End of April 2020

Expected return date:
Awaiting update
Last updated:
2nd July 2020 
Lanoxin 500mcg/2ml Solution for Injection

PA1691/001/001 
Digoxin  Manufacturing delays  Date of shortage:
End of April 2020

Expected return date:
Mid August 2020 
Last updated:
15th May 2020 
Lanoxin PG 62.5mcg Tablet 

PA1691/001/003
Digoxin  Manufacturing delays  Date of shortage:
10th February 2020

Expected return date:
Mid July 2020
Last updated:
15th May 2020 

HCP Letter
Lanoxin PG 50mcg/ml Elixir

PA1691/001/002 
Digoxin  Manufcaturing delays  Date of shortage:
Mid May 2020

Expected return date:
End July 2020 
Last updated:
29th May 2020 
Lanoxin PG 250mcg Tablet

PA1691/001/004 
Digoxin  Manufacturing delays  Date of shortage:
17th March 2020

Expected return date:
End July 2020 
Last updated:
29th May 2020 
Lercanidipine Mylan 10mg Tablet

PA0577/155/001
Lercanidipine  Unexpected increase in demand  Date of shortage:
Early November 2019

Expected return date:
October 2020 
Last updated:
21st January 2020 
Lercanidipine Mylan 20mg Tablet

PA0577/155/002 
Lercanidipine  Unexpected increase in demand  Date of shortage:
Early November 2019

Expected return date:
October 2020 
Last updated:
21st January 2020
Levofloxacin 250mg Tablet

PA1347/048/001 
Levofloxacin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
20th April 2020

Expected return date:
4th August 2020 
Last updated:
1st July 2020 
Lipantil 145mg Film Coated Tablet

PA2010/015/003 
Fenofibrate  Manufacturing delays  Date of shortage:
24th June 2020

Expected return date:
August 2020
Last updated:
30th June 2020 
Losamel 20mg Gastro-resistant tablets

PA0126/115/001
Omeprazole Manufacturing delays Date of shortage: 
1st April 2020

Expected return date:
Unknown at present
Last updated:
24th April 2020 
Losartan 50mg Tablet 

PA2315/059/002 
Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
April 2021 
Last updated:
22nd April 2020
Losartan 100mg Tablet

PA0749/090/004 
Losartan  Unavailability of API

(multiple countries affected) 
Date of shortage:
Early January 2020

Expected return date:
Awaiting update
Last updated:
2nd July 2020 
Losartan 100mg Tablet

PA2315/059/003 
Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
April 2021
Last updated:
22nd April 2020 
Losartan Hydrochlorothiazide 50mg/12.5mg Tablet

PA0749/026/001 
Losartan & Hydrochlorothiazide  Unavailability of API

(multiple countries affected) 
Date of shortage:
24th November 2019

Expected return date:
Unknown at present
Last updated:
17th June 2020 
Lotanos 100mg Film coated Tablet

PA0711/123/005 
Losartan  Unexpected increase in demand  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present 
Last updated:
4th June 2020 
Lyrica 75mg Capsule

EU/1/04/279/012 
Pregabalin  Manufacturing delays  Date of shortage:
End of June 2020

Expected return date:
Week commencing 20th July 2020 
Last updated:
26th June 2020 
Lyrica 300mg Capsule

EU/1/04/279/024 
Pregabalin  Manufacturing delays  Date of shortage:
Week commencing 22nd June 2020

Expected return date:
Early August 2020 
Last updated:
17th June 2020 
Mefac 250mg Capsule

PA0074/015/001 
Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Q1 2021
Last updated:
29th April 2020
 
Melcam 7.5mg Tablet

PA0711/060/001 
Meloxicam  Manufacturing delays  Date of shortage:
November 2019

Expected return date:
2nd August 2020
Last updated:
16th June 2020 
Minims Atropine Sulphate 1% Eye Drop Solution

PA0555/017/001 
Atropine  Manufacturing delays  Date of shortage:
July 2019

Expected return date:
End of July 2020
Last updated:
5th March 2020 
Minims Prednisolone 0.5% Eye Drop Solution

PA22698/016/001 
Prednisolone  Unavailability of API

(multiple countries affected)
Date of shortage:
End of May 2020

Expected return date:
July 2020 
Last updated:
22nd May 2020 
Miramel 0.088mg Tablet

PA0126/173/001 
Pramipexole  Manufacturing delays  Date of shortage:
Early May 2020

Expected return date:
Early July 2020 
Last updated:
2nd June 2020 
Miramel 0.18mg Tablet

PA0126/173/002 
Pramipexole  Manufacturing delays  Date of shortage:
Early May 2020

Expected return date:
Early July 2020 
Last updated:
2nd June 2020 
Morphine Sulphate Injection BP 30mg/ml Solution for Injection

PA0361/004/005 
Morphine Sulphate  Manufacturing delays  Date of shortage:
October 2018

Expected return date:
During 2020
Last updated:
16th October 2019 
Muse 250mcg Urethral Stick

PA2010/028/002
Alprostadil  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid March 2019
 
Expected return date:
Unknown at present
Last updated:
25th May 2020
Neurontin 300mg Capsule

PA0822/015/002 
Gabapentin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
End of June 2020

Expected return date:
End of July 2020 
Last updated:
3rd June 2020

HCP Letter 
Neurontin 800mg Capsule

PA0822/015/005 
Gabapentin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
End of June 2020

Expected return date:
End of July 2020 
Last updated:
3rd June 2020

HCP Letter 
Nimbex 2mg/ml Solution for Infusion/Injection

PA1691/030/001
Cistatracurium  Unexpected increase in demand

(multiple countries affected) 
Date of shortage:
April 2020

Expected return date:
August 2020 
Last updated:
13th May 2020 
Novolizer 200mg Budesonide Inhalation Powder

PA2010/032/001 
Budesonide  Unexpected increase in demand  Date of shortage:
26th March 2020

Expected return date:
Early July 2020 
Last updated:
28th May 2020 
Novolizer 100mcg Salbutamol Inhalation Powder

PA2010/033/001
Salbutamol  Unexpected increase in demand  Date of shortage:
26th March 2020

Expected return date:
September 2020 
Last updated:
1st April 2020 
Oprymea 0.088mg Tablet

EU/1/08/469/001-005 
Pramipexole  Manufacturing delay  Date of shortage:
End of May 2020

Expected return date:
End of September 2020 
Last updated:
3rd June 2020 
Perdamel 0.5mg Film Coated Tablet

PA0126/169/002 
Risperidone  Manufacturing delays  Date of shortage:
20th January 2020

Expected return date:
Mid July 2020 
Last updated:
5th May 2020 
Piperacillin with Tazobactam 2.25g Powder for Solution for Injection

PA1339/001/001 
Piperacillin sodium & Tazobactam sodium Manufacturing delays

(multiple countries affected)
Date of shortage:
January 2018

Expected return date:
Unknown at present
Last updated:
12th July 2019
Piperacillin with Tazobactam 4.5g Powder for Solution for Injection

PA1339/001/002 
Piperacillin sodium & Tazobactam sodium Manufacturing delays

(multiple countries affected)
Date of shortage:
January 2018

Expected return date:
Unknown at present
Last updated:
12th July 2019
Pneumovax 23 Solution for Injection in Pre-filled Syringe

PA1286/055/002 
Pneumococcal Polysaccharide Vacine  Unexpected increase in demand

(multiple countries affected)
Date of shortage:
16th March 2020

Expected return date:
July 2020 
Last updated:
23rd March 2020 
Prozamel 20mg Cpasule

PA0126/110/001 
Fluoxetine  Manufcaturing delays
 
Date of shortage:
End of March 2020

Expected return date:
Mid October 2020 
Last updated:
24th March 2020 
Questran 4g Powder for Oral Suspension

PA2239/005/001 
Colestyramine  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid June 2019

Expected return date:
Q1 2021 
Last updated:
22nd April 2020 
Rifadin 300mg Capsule

PA0540/066/002 
Rifampicin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
19th June 2020

Expected return date:
31st July 2020 
Last updated:
19th June 2020 
Rispone 6mg Film Coated Tablet

PA0711/106/005 
Risperidone  Manufacturing delays  Date of shortage:
End of April 2020

Expected return date:
Awaiting update 
Last updated:
23rd June 2020 
Salazopyrin 500mg Tablet

PA0822/196/002 
Sulfasalazine  Manufacturing delays 

(multiple countries affected)
Date of shortage:
30th June 2020

Expected return date:
End of October 2020 
Last updated:
30th June 2020

HCP Letter 
Sertraline 50mg Film Coated Tablet

PA2315/101/003 
Sertraline  Unavailability of API

(multiple countries affected) 
Date of shortage:
January 2020

Expected return date:
End of July 2020 
Last updated:
3rd July 2020 
Sildenafil 100mg Film Coated Tablet

PA0126/199/003
Sildenafil Unexpected increase in demand Date of shortage:
20th April 2020

Expected return date:
6th July 2020
 Last updated:
 
3rd July 2020
Sofradex Ear/Eye Drops

PA0540/070/002 
Framycetin, Gramicidin & Dexamethasone  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid January 2020

Expected return date:
Unknown at present
Last updated:
10th March 2020 
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 
Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
September 2020 
Last updated:
3rd December 2019 
Stilnoct 5mg Tablet

PA0540/160/001 
Zolpidem   Increased demand  Date of shortage:
End of June 2020

Expected return date:
Mid July 2020 
Last updated:
25th June 2020 
Sumatriptan 100mg Film Coated Tablet

PA2315/070/002
 
Sumatriptan  Manufacturing delays  Date of shortage:
Early April 2020

Expected return date:
September 2020 
Last updated:
17th April 2020 
Tefin 75mg Suppositories

PA1684/001/001 
Ibuprofen  Manufacturing delays  Date of shortage:
August 2019

Expected return date:
Mid September 2020
Last updated:
16th June 2020
Tefin 150mg Suppositories

PA1684/001/002 
Ibuprofen  Manufacturing delays  Date of shortage:
August 2019

Expected return date:
Mid September 2020 
Last updated:
16th June 2020 
Temozolomide 5mg Capsule

EU/1/09/606/001-002 
Temozolomide  Unavailability of API  Date of shortage:
Mid June 2020

Expected return date:
October 2020 
Last updated:
17th June 2020 
Teveten 400mg Film Coated Tablet

PA2010/017/001
Eprosartan  Manufacturing delays  Date of shortage:
Mid June 2020

Expected return date:
Unknown at present 
Last updated:
17th June 2020 
Tipol 250mg Suppository

PA1684/002/003 
Paracetamol  Manufactuirng delays  Date of shortage:
Early April 2020

Expected return date: 
Mid September 2020 
Last updated:
16th June 2020 
Tipol 500mg Suppository

PA1684/002/004 
Paracetamol  Manufacturing delays  Date of shortage:
Early April 2020

Expected return date:
Mid September 2020 
Last updated:
16th June 2020 
TOBI 300mg/5ml Nebuliser Solution

PA2010/063/001 
Tobramycin  Manufacturing delays  Date of shortage:
23rd June 2020

Expected return date:
Unknown at present 
Last updated:
29th June 2020 
Trandate 100mg Film Coated Tablet

PA1638/006/002 
Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 
Date of shortage:
July 2019

Expected return date:
August 2020
Last updated:
6th April 2020 
Trandate 200mg Film Coated Tablet

PA1638/006/003 
Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 
Date of shortage:
July 2019

Expected return date:
August 2020
Last updated:
6th April 2020
Tranexamic acid 100mg/ml Solution for Injection

PA2315/178/001 
Tranexamic acid  Manufacturing delays  Date of shortage:
Early July 2019

Expected return date:
Unknown at present 
Last updated:
1st May 2020 
Ranitic 75mg Film Coated Tablet

PA0711/024/004 
Ranitidine  Active substance impurity

(multiple countries affected) 
Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 
Last updated:
22nd October 2019

MMP Guidance for Prescribers
             
AHDMP Guidance for Prescribers
Ranitic 150mg Film Coated Tablet

PA0711/024/001 
Ranitidine  Active substance impurity

(multiple countries affected) 
Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 
Last updated:
22nd October 2019

MMP Guidance for Prescribers

AHDMP Guidance for Prescribers
 
Ranitic 300mg Film Coated Tablet

PA0711/024/002 
Ranitidine  Active substance impurity

(multiple countries affected) 
Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 
Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Ranitidine 150mg/10ml Oral Solution

PA22741/009/001 
Ranitidine  Active substance impurity

(multiple countries affected) 
Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 
Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Ultiva 5mg Powder for Concentrate for Solution for Infusion

PA1691/032/003 
Remifentanyl  Unexpected increase in demand  Date of shortage:
8th June 2020

Expected return date:
Early August 2020 
Last updated:
8th June 2020 
Valsartan Actavis 40mg Film Coated Tablet 

PA1380/022/001
Valsartan Active substance impurity

(multiple countries affected)
                        
Date of shortage:
July 2018

Expected return date:
Awaiting update
Last updated: 
14th January 2020
Valsartan Actavis 80mg Film Coated Tablet

PA1380/022/002
     
Valsartan Active substance impurity

(multiple countries affected)
Date of shortage:
July 2018

Expected return date:
Awaiting update
Last updated:
14th January 2020
Valsartan Actavis 160mg Film Coated Tablet 

PA1380/022/003
Valsartan Active substance impurity

(multiple countries affected)
Date of shortage:
July 2018

Expected return date:
Awaiting update
 
Last updated:
14th January 2020
Valsartan Teva 80mg Film Coated Tablet

PA0749/084/002 
Valsartan Unexpected increase in demand

(multiple countries affected)
Date of shortage:
July 2018

Expected return date:
Unknown at present
Last updated:
6th April 2020
Valsartan Teva 160mg Film coated Tablet

PA0749/084/003 
Valsartan  Unexpected increase in demand

(multiple countries affected)
Date of shortage:
Awaiting update

Expected return date:
Unknown at present
Last updated:
6th April 2020
Valsartan / Hydrochlorothiazide 160mg/ 25mg Film Coated Tablet

PA2315/181/003 
Valsartan & Hydrochlorothiazide Active substance impurity

(multiple countries affected)
Date of shortage:
July 2018

Expected return date:
Awaiting update
Last updated: 
21st February 2020
Vatan 40mg Film Coated Tablet

PA0711/183/001
Valsartan  Active substance impurity

(multiple countries affected) 
Date of shortage:
July 2018

Expected return date:
Awaiting update
Last updated:
18th November 2019
Vatan 80mg Film Coated Tablets

PA0711/183/002 
Valsartan  Active Substance Impurity

(multiple countries affected) 
Date of shortage:
July 2018

Expected return date:
Awaiting update
Last updated:
18th November 2019
Vatan 160mg Film Coated Tablets

PA0711/183/003 
Valsartan Active Substance impurity

(multiple countries affected) 
 
Date of shortage:
July 2018

Expected return date:
Awaiting update
Last updated:
18th November 2019
Vedixal 37.5mg Tablet

PA0711/161/002 
Venlafaxine  Manufacturing delay  Date of shortage:
22nd April 2020

Expected return date:
12th August 2020
Last updated:
23rd June 2020 
Venlafaxine XL 37.5mg Prolonged Release Capsule

PA1347/036/001 
Venlafaxine  Unexpected increase in demand  Date of shortage:
End of March 2020

Expected return date:
Mid July 2020 
Last updated:
6th April 2020 
Venex XL 37.5mg Prolonged-Release Capsule

PA0126/285/001
 Venlafaxine Manufacturing delay Date of shortage:
07/05/2020

Expected return date:
Unknown at present
Last updated:
7th May 2020 
Venex XL 150mg Prolonged-Release Capsule

PA0126/285/003 
Venlafaxine  Manufacturing delay  Date of shortage:
Mid May 2020

Expected return date:
Unknown at present 
Last updated:
15th May 2020 
Verap 120mg Prolonged Release Tablet

PA0711/016/004 
Verapamil  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
End of 2020
Last updated:
28th April 2020 
Zacin 0.025% w/w Cream

PA0827/008/001 
Capsaicin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid July 2019

Expected return date:
End of July 2020 
Last updated:
17th June 2020 
Zaditen 1mg Tablet

PA2206/004/002 
Ketotifen  Manufacturing delays  Date of shortage:
Early 2020

Expected return date:
Unkown at present 
Last updated:
5th June 2020 
Zinnat 250mg Tablet

PA1077/015/003 
Cefuroxime  Manufacturing delays  Date of shortage:
6th July 2020

Expected return date:
Early August 2020 
Last updated:
12th June 2020 
Zoely 2.5mg/1.5mg Film Coated Tablet 

EU/1/11/690/001
Nomegestrol acetate & Esradiol  Unavailability of API

(multiple countries affected) 
Date of shortage:
Early August 2019

Expected return date:
End of 2020
Last updated:
27th January 2020
 
HCP Letter
Zolmitriptan 2.5mg Orodispersible Tablet

PA1380/035/003 
Zolmitriptan  Manufacturing delays  Date of shortage:
Mid May 2020

Expected return date:
September 2020 
Last updated:
11th May 2020 
Zomig 2.5mg Tablet

PA2242/004/001 
Zolmitriptan  Manufacturing delays  Date of shortage:
12th June 2020

Expected return date:
August 2020 
Last updated:
10th June 2020 

Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL




Contact us:

Medicinal Product Shortages Unit
Health Products Regulatory Authority 
Kevin O’Malley House
Earlsfort Terrace,
Dublin 2
Tel: +353 1 676 4971
Fax: +353 1 676 7836
shortages@hpra.ie