My HPRA: Register

Medicines Shortages

The HPRA is responsible for coordinating the management of human medicine shortages on the Irish market. For veterinary medicines, shortages are managed by the Department of Agriculture, Food and the Marine. 

The definition of a shortage is when the supply of a medicinal product is inadequate to meet the needs of the patient. 

For many medicines supplied in Ireland, there is more than one strength, form, pack size or brand available from different suppliers. Your doctor or pharmacist will often be able to supply an alternative strength, form or product to ensure continuity of treatment if the medicine you have been taking is unavailable.

 

We recognise that medicine shortages can be challenging for those who rely on medicines for their health and well-being. The published information in relation to medicine shortages is regularly updated to keep patients and healthcare professionals informed of current and resolved shortages.

 

How are medicinal product shortages handled in Ireland?

The HPRA works with various stakeholders, including manufacturers, wholesale distributors, marketing authorisation holders, healthcare professionals, the Health Service Executive, patients and representative groups to respond to potential shortages and reduce the impact of shortages on patients. A framework for a multi-stakeholder approach to handling shortages of human medicinal products has been developed and published.

The framework aims to help prevent shortages and reduce patient impact by coordinating the management of potential or actual shortages as they arise. You can see the shortages case study on Adrenaline auto-injectors (AAIs) as an example of how the framework operates in practice. 

Mitigation and prevention strategies

The HPRA has reviewed data from the first two years of operation of the shortage framework to help develop future strategies for handling shortages and their prevention in Ireland. Following consultation with stakeholders, the Two-year Review has been published and outlines the strategy for the next phase of the framework.

 

Information on reporting shortages for:

Marketing Authorisation Holders

Please complete the Notification of medicinal product shortage from marketing authorisation holder form and return to  shortages@hpra.ie and to the HSE Corporate Pharmaceutical Unit.

Wholesale Distributors and Manufacturers

Please complete the Report of medicinal product shortage affecting the Irish market from wholesale distributors and manufacturers form and return this form to  shortages@hpra.ie.

Patients and Healthcare Professionals

Please complete the Report of medicinal product shortage affecting the Irish market from patients and healthcare professionals form and return to  shortages@hpra.ie. When completing this form, please include as much information as possible.

Veterinary Medicines

Please contact the Department of Agriculture, Food and the Marine.

 

Current and resolved shortages

The HPRA publishes a list of shortages currently affecting the Irish market that have been notified to us and that may have a medium or high impact on patients. This list can be found below. More information on the impact level can be found in the framework for a multi-stakeholder approach to handling shortages of human medicinal products

The HPRA maintains a consolidated list of resolved shortages for a period of six months. Details of shortages that have been resolved in the last six months can be found here.

Ozempic supply

Novo Nordisk, the marketing authorisation holder for Ozempic, has notified the HPRA of intermittent supply issues with Ozempic products, due to a global increased demand. The company anticipates that intermittent supply will continue into 2023.

Novo Nordisk has implemented monthly allocations to help ensure continuity of supply and equitable distribution of Ozempic stock to Irish patients. The company has issued letters to relevant stakeholders, including healthcare professionals to ensure they are aware of this supply issue and how it is being managed.

Concerta supply

Janssen, the company that places the Concerta XL products on the market has informed the HPRA that it is encountering global supply chain issues related to component availability and increased demand in multiple markets. The company has stated that there are allocations in place to ensure equitable distribution to mitigate the impact on patients in Ireland and that it is working closely with pharmacies to ensure patients receive their medication. The company has advised that if there are any localised supply issues, pharmacies can contact Janssen medical information, on 1800709122, so that the required quantity can be released for the patient. Janssen has advised to only order the amount of Concerta XL that you need in a given month as the company attempts to build stock levels back up. Ordering more than necessary could result in increased pressure on the supply levels at a national level.

Medicines availability – Responding to increased demand due to winter seasonal illness

Due to a combination of factors, including the level of respiratory illnesses in the community, a significant increase in demand for medicines used to treat seasonal conditions such as colds and flu has been observed over recent weeks. In some cases, this demand has been 2-3 times the average level seen during the same period in previous years. From discussions with suppliers and regulators in other countries, the HPRA understands that similar trends have been observed in other European countries that have experienced significant demand increases.

The HPRA has been engaging with all stakeholders, including suppliers, to ensure a coordinated response to this increased demand. The key focus at all times has been to ensure that suitable medicines remain available to treat patients.

In the case of medicines used most often in Ireland, there are typically multiple forms, strengths, brands, and generic medicines available from various sources. Where some individual medicines are in short supply, alternative options such as alternative strengths, brands, and generic medicines remain available to ensure continuity of treatment. In some cases where the medicine initially prescribed for the patient is unavailable, patients may be switched to a suitable therapeutic alternative following appropriate consultation with a healthcare professional. This approach is also consistent with national antimicrobial prescribing guidelines.

Suitable medicines continue to be available to treat respiratory illnesses and their symptoms in both adults and children. Taking into account the wide range of available medicines to treat respiratory illnesses, there is no need for healthcare professionals to order extra quantities of medicines, or for doctors to issue additional prescriptions. Similarly, patients and the general public are asked not to seek supplies of medicines over and above their normal requirements. Doing so will disrupt existing stock levels and hamper the supply of medicines for others.

Further to the HPRA’s regular and ongoing engagement with industry, we have been informed that in a number of instances suppliers have increased production and sourced additional stock to respond to this recent increase in demand. Although the HPRA has no role in procuring medicines, we continue to engage with the suppliers to obtain updates and remain open to expediting regulatory procedures to enable the supply of additional stock, where possible.

Regarding antibiotic supply, the HSE has published advice for GPs, pharmacists and other healthcare professionals on managing common respiratory infections during the 2022/2023 winter season.

Respiratory Infections 2023 Winter Season: Advice & Antibiotic Supply - HSE.ie

This information, which includes advice and updates on antibiotic supply, will be updated daily by the HSE in consultation with the HPRA based on information from suppliers.

Specific shortages, as notified to the HPRA, are listed below.




Please use search function below to find relevant product or active ingredient


Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abstral 100mcg  Sublingual Tablets

PA2288/004/002

Kyowa Kirin Holdings B.V.
 Fentanyl   Manufacturing delay   Date of shortage: 
Early March 2023

Expected return date: 
Week ending 9th April 2023		 Last updated: 
27th March 2023 
Abstral 200mcg Sublingual Tablets

PA2288/004/003

Kyowa Kirin Holdings B.V.
  Fentanyl Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
23rd March 2023

Expected return date:
Week ending 23rd April 2023		 Last updated: 
28th March 2023 
Abstral 300mcg Sublingual Tablets

PA2288/004/004

Kyowa Kirin Holdings B.V.
 Fentanyl  Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Week commencing 5th December 2022

Expected return date: 
Week ending 23rd April 2023		 Last updated: 
28th March 2023
Abstral 400mcg Sublingual Tablets

PA2288/004/005

Kyowa Kirin Holdings B.V.
 Fentanyl  Unexpected increase in demand  Date of shortage: 
Late December 2023

Expected return date: 
Week ending 9th April 2023		 Last updated: 
27th March 2023
Abstral 600mcg Sublingual Tablets

PA2288/004/006

Kyowa Kirin Holdings B.V.
 Fentanyl   Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
End of January 2023

Expected return date:
Week ending 9th April 2023		 Last updated: 
27th March 2023
Actilyse Cathflo 2mg Powder for Solution for Injection and Infusion

PA0775/011/001

Boehringer Ingelheim International GmbH
 Alteplase
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
Week commencing 9th May 2022

Expected return date: 
2024 		 Last updated: 
10th May 2022

HCP letter
Adenuric 80mg Film-coated Tablet 

EU/1/08/447/001 

Menarini International Operations Luxembourg S.A.
 Febuxostat
 Manufacturing delay  Date of shortage: 
Week ending 26th March.

Expected return date: 
Week ending 16th April 2023		 Last updated: 
21st March 2023 
Alka-Seltzer Effervescent Tablets

(10 pack)

PA1410/032/001

Bayer Limited
 Sodium hydrogen carbonate, aspirin & citric acid  Manufacturing delay  Date of shortage: 
31st March 2023

Expected return date: 
September 2023		 Last updated: 
20th March 2023
Allopurinol Teva 300mg Tablets

PA0749/099/003

Teva Pharma B.V.
  Allopurinol  Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
13th February 2023

Expected return date: 
Week ending 2nd April 2023 		 Last updated: 
30th January 2023 
Alprazolam 0.25 mg Tablets

PA0711/140/001

Rowex Ltd
  Alprazolam Unexpected increase in demand Date of shortage: 
28th February 2023

Expected return date:
May 2023 		 Last updated: 
28th March 2023 
Alprazolam 0.5 mg Tablets

PA0711/140/002

Rowex Ltd
 Alprazolam  Shipping delay Date of shortage: 
13th January 2023

Expected return date: 
April 2023		 Last updated: 
1st February 2023
Aminophylline Hydrate 25mg/ml Solution for Injection

PA0073/099/001

Mercury Pharmaceuticals (Ireland) Ltd
 Aminophyline Unexpected increase in demand  Date of shortage: 
End of January 2023

Expected return date: 
Week commencing 16th April 2023		 Last updated:
27th March 2023
Amorolfine 5%w/v Medicated Nail Lacquer

PA0711/309/001

Rowex Ltd
 Amorolfine  Manufacturing delay Date of shortage: 
Late August 2022

Expected return date: 
April 2023		 Last updated: 
28th March 2023
Antabuse 400mg Effervescent Tablets

PA1986/110/001


Teva B.V.
 Disulfiram
  API unavailability 

(multiple countries affected)		 Date of shortage: 
Week commencing 25th July 2022

Expected return date: 
June 2023		 Last updated: 
22nd March 2023
Apidra Solostar 100 units/ml Solution for Injection in a Pre-Filled Pen

EU/1/04/285/032

Sanofi-Aventis Deutschland GmbH
 Insulin glulisine
 Manufacturing delay 

(multiple countries affected)		 Date of shortage:
23rd March 2023

Expected return date: 
Week ending 23rd April 2023 		 Last updated:
22nd March 2023 
Arava 20mg Film Coated Tablets

EU/1/99/118/007

Sanofi-Aventis Deutschland GmbH
 Leflunomide
 Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
19th December 2022

Expected return date: 
Awaiting update		 Last updated: 
20th March 2023
Artelac 3.2mg/ml Eye Drops, Solution 

PA23259/004/001

Bausch + Lomb Ireland Limited
 Hypromellose
 Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
Late July 2022

Expected return date: 
Week ending 9th April 2023		 Last updated: 
21st February 2023
Artelac Preservative Free Single Dose Unit

PA23259/004/002 

Bausch + Lomb Ireland Limited
 Hypromellose  Manufacturing delay Date of shortage: 
21st February 2023

Expected return date: 
Week ending 16th April 2023		 Last updated: 
21st February 2023 
Aspirin 300mg Effervescent Tablets

PA1410/037/001

Bayer Limited		  Aspirin Manufacturing delay  Date of shortage: 
15th March 2023

Expected return date: 
Week ending 11th June 2023		 Last updated: 
6th March 2023 
Atenomel 50mg Tablets

PA0126/069/001

Clonmel Healthcare Ltd
 Atenolol Unexpected increase in demand  Date of shortage: 
30th November 2022

Expected return date: 
Early June 2023 		 Last updated: 
23rd November 2022 
Atozet 10mg/10mg Film-Coated Tablets 

PA23198/022/01

Organon Pharma (Ireland) Limited
 Ezetimibe & atorvastatin Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
End of February 2023

Expected return date: 
End of March 2023 		 Last updated: 
13th February 2023 
Atozet 10mg/20mg Film-Coated Tablets

PA23198/022/002

Organon Pharma (Ireland) Limited
 Ezetimibe & atorvastatin
 Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
11th January 2023

Expected return date:
April 2023		 Last updated:
18th January 2023 
Azithromycin Clonmel 250mg Film Coated Tablets

PA0126/150/001

Clonmel Healthcare Ltd
 Azithromycin  Quality issue 

(multiple countries impacted)		 Date of shortage: 
Week commencing 18th April 2022

Expected return date: 
Week ending 9th April 2023		 Last updated: 
16th March 2023
Azyter 15mg/g Eye Drops

PA1107/004/001

Laboratoires Thea
 Azithromycin
 Unexpected increase in demand Date of shortage: 
Week ending 5th March 2023

Expected return date: 
April 2023 		 Last updated: 
17th February 2023 
Benylin Children’s Dry Coughs Syrup

PA0330/022/001

Johnson & Johnson (Ireland) Limited
 Diphenhydramine & levomenthol  Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
16th December 2022

Expected return date:
Awaiting update		 Last updated:
28th February 2023 
Benylin Cough Medicine Syrup

PA0330/019/001

Johnson & Johnson (Ireland) Limited
 Diphenhydramine & levomenthol
 Unexpected increase in demand  Date of shortage: 
16th December 2022

Expected return date: 
Awaiting update		 Last updated: 
24th March 2023
Benylin Dual Action Dry Syrup

PA0330/015/002

Johnson & Johnson (Ireland) Limited
 Dextromethorphan, pseudoephedrine & triprolidine  Unexpected increase in demand  Date of shortage: 
Early December 2022

Expected return date: 
April 2023		 Last updated: 
12th January 2023
Benylin Phlegm Cough plus Decongestant Syrup

PA0330/032/001

Johnson & Johnson (Ireland) Limited
 Guaifenesin and pseudoephedrine
 Unexpected increase in demand Date of shortage: 
19th December 2022

Expected return date: 
April 2023		 Last updated: 
12th January 2023
Betnovate Cream 0.1% w/w 

PA1077/001/001

GlaxoSmithKline (Ireland) Limited
 Betamethasone  Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
Early December 2022

Expected return date:
2024		 Last updated:
7th February 2023 
Bisolvon 4mg/5ml Oral Solution

PA23180/015/001

Opella Healthcare France SAS T/A Sanofi
 Bromhexine
 Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
18th January 2023

Expected return date: 
May 2023 		 Last updated: 
23rd January 2023 
Brolene 0.15% w/w Eye Ointment

PA0126/357/002

Clonmel Healthcare Ltd
 Dibromopropamidine
 Unexpected increase in demand Date of shortage: 
21st March 2022

Expected return date: 
Week ending 2nd April 2023		 Last updated: 
21st February 2023
Brupro Cold & Flu 200 mg/30 mg film-coated tablets

PA0074/067/006

Rowa Pharmaceuticals Limited
 Ibuprofen & pseudoephedrine hydrochloride  Unexpected increase in demand  Date of shortage: 
13th January 2023

Expected return date: 
May 2023 		 Last updated: 
25th January 2023 
Caelyx 2mg/ml
Pegylated Liposomal Concentrate for Solution

(25ml presentation)

EU/1/96/011/003-004

Baxter Holding B.V.
 Doxorubicin Manufacturing delays

(multiple countries affected)		 Date of shortage: 
Late October 2022

Expected return date:
Awaiting update		 Last updated: 
16th February 2023
Canesten 500mg Pessary

PA1410/039/009

Bayer Limited		  Clotrimazole Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
15th March 2023

Expected return date: 
Awaiting update		 Last updated: 
27th March 2023
Canesten Combi Pessary & Cream

PA1410/039/001

Bayer Limited
 Clotrimazole  Manufacturing delay   Date of shortage: 
31st March 2023

Expected return date:
Week ending 9th April 2023		 Last updated: 
15th March 2023 
Cardura XL 4mg Prolonged Release Tablets

PA23355/001/001

Viatris Healthcare Limited
 Doxazosin  Manufacturing delay Date of shortage: 
 23rd December 2022

Expected return date: 
Week ending 23rd April 2023		 Last updated: 
13th March 2023
Ciplox 250mg Film-Coated Tablets

PA2315/100/001

Accord Healthcare Ireland Ltd
  Ciprofloxacin Unexpected increase in demand  Date of shortage: 
Week ending 19th March 2023

Expected return date: 
Unknown at present 		 Last updated: 
27th February 2023 
Ciplox 500mg Film-Coated Tablets

PA2315/100/001

Accord Healthcare Ireland Ltd.
 Ciprofloxacin Unexpected increase in demand Date of shortage: 
Week ending 13th February 2023 

Expected return date: 
Unknown at present		 Last updated: 
31st January 2023 
Clarithromycin Teva 250mg Film Coated Tablets

PA0749/148/001

Teva Pharma B.V.
  Clarithromycin Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
8th March 2023

Expected return date: 
Week ending 7th May 2023		  Last updated: 
6th March 2023
Clarithromycin 500 mg film-coated tablets

PA2050/002/002 

Sun Pharmaceutical Industries Europe B.V.
  Clarithromycin Unexpected increase in demand Date of shortage: 
End of January 2023

Expected return date: 
Week ending 11th June 2023 		 Last updated: 
17th January 2023 
Clorom 500mg Tablets

PA0711/061/002

Rowex Ltd 
 Clarithromycin  Unexpected increase in demand  Date of shortage: 
31st January 2023

Expected return date:
May 2023		 Last updated:
1st March  2023 
Clavamel Forte 500mg/125mg Film Coated Tablet

PA0126/243/001

Clonmel Healthcare Ltd
 Amoxicillin & clavulanic acid  Unexpected increase in demand  Date of shortage: 
19th December 2022

Expected return date: 
Week ending 4th June 2023		 Last updated: 
17th February 2023
Cardura XL 8mg Prolonged Release Tablets

PA23355/001/002

Viatris Healthcare Limited
  Doxazosin Manufacturing delay  Date of shortage: 
23rd December 2022

Expected return date: 
Awaiting update		 Last updated: 
27th March 2023
Caverject 10mcg Powder and Solvent for Solution for Injection

PA0822/115/002

Pfizer Healthcare Ireland
  Alprostadil  Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Week ending 12th February 2023

Expected return date:
Awaiting update		 Last updated: 
27th March 2023
Ceftazidime 1g Powder for solution for injection or infusion

PA0281/224/001

Pinewood Laboratories Ltd
 Ceftazidime
 Unexpected increase in demand  Date of shortage: 
Early January 2023

Expected return date: 
April 2023		 Last updated:
14th February 2023
Centrax 10mg Tablets

PA0822/010/001

Pfizer Healthcare Ireland
 Prazepam
 Quality issue

(multiple countries affected) 		 Date of shortage: 
End June 2022 

Expected return date: 
Late 2023		 Last updated: 
8th September 2022
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001

Pfizer Europe MA EEIG
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005

Pfizer Europe MA EEIG
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003

Pfizer Europe MA EEIG
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Clarithromycin 500mg Film Coated Tablets

PA2315/136/004

Accord Healthcare Ireland Ltd.
  Clarithromycin Unexpected increase in demand  Date of shortage: 
28th November 2022

Expected return date; 
Awaiting update		 Last updated: 
16th March 2023
Clarithromycin Teva 500mg Film Coated Tablets

PA0749/148/002

Teva Pharma B.V.
  Clarithromycin Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
Early January 2023

Expected return date: 
May 2023 		 Last updated: 
4th January 2023 
Colofac 135mg Tablets 

PA2010/007/001

Mylan IRE Healthcare Limited
 Mebeverine Manufacturing delay  Date of shortage: 
Week ending 2nd April 2023

Expected return date: 
Awaiting update		 Last updated: 
13th March 2023
Cosartal Plus 50mg/12.5mg Film Coated Tablets

PA2315/190/001

Accord Healthcare Ireland Ltd.
 Losartan & hydrochlorothiazide
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Early February 2022

Expected return date: 
Unknown at present 
 Last updated: 
12th January 2023
Cosartal Plus 100mg/25mg Film Coated Tablets

PA2315/190/002

Accord Healthcare Ireland Ltd.
 Losartan & hydrochlorothiazide
 Quality issue

(multiple countries affected)		 Date of shortage: 
Early February 2022 

Expected return date: 
Unknown at present 		 Last updated: 
12th January 2023
Creon 25000 Gastro-resistant Capsules

PA2010/008/002

Mylan IRE Healthcare Limited
  Pancreas powder Shipping delay   Date of shortage: 
Mid March 2023

Expected return date: 
Awaiting update		 Last updated: 
27th March 2023 
Dalmane 15mg Hard Capsules

PA2010/039/001

Mylan IRE Healthcare Limited
 Flurazepam API unavailability 

(multiple countries affected) 		 Date of shortage: 
Week ending 19th March 2023

Expected return date: 
October 2023		 Last updated: 
9th March 2023 
Dalmane 30mg Hard Capsules

PA2010/039/002

Mylan IRE Healthcare Limited
 Flurazepam
 API unavailability

(multiple countries affected)		 Date of shortage: 
28th January 2023

Expected return date: 
October 2023		 Last updated: 
19th January 2023 
Deslor 5mg Film-Coated Tablets

PA0711/202/001

Rowex Ltd
  Desloratadine Manufacturing delay Date of shortage: 
31st January 2023

Expected return date: 
July 2023		 Last updated: 
28th March 2023
Desmospray Desmopressin Nasal Spray

PA1009/005/001 

Ferring Ireland Ltd
 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
Late 2023		 Last updated:
9th February 2022 
Detrusitol SR 2 mg, Prolonged-release Capsules

PA23055/007/001

Upjohn EESV
 Tolterodine
 API unavailability   Date of shortage: 
12th January 2023

Expected return date:
Awaiting update		  Last updated: 
27th March 2023
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 

Accord Healthcare Ireland Ltd.
 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Difene 25mg Capsules

PA2256/001/001

Glenwood GmbH
 Diclofenac  Manufacturing delays  Date of shortage: 
December 2022

Expected return date: 
Early April 2023 		 Last updated: 
20th February 2023 
Diflucan 40mg/ml Powder for Oral Suspension 

PA0822/211/007

Pfizer Healthcare Ireland
 Fluconazole  Quality issue

multiple countries affected 		 Date of shortage: 
27th March 2023

Expected return date: 
Unknown at present		 Last updated: 
28th March 2023 
Dioralyte Citrus Powder for Oral Solution

PA23180/006/002

Opella Healthcare France SAS T/A Sanofi
 Sodium chloride, potassium chloride, glucose & disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
Awaiting update
 Last updated: 
15th March 2023
Dioralyte Natural, Powder for Oral Solution 

PA23180/007/001

Opella Healthcare France SAS T/A Sanofi
 Sodium chloride, potassium chloride, glucose & disodium hydrogen citrate
 Manufacturing delays  Date of shortage:
June 2022

Expected return date:
Awaiting update		 Last updated:
13th March 2023
Dioralyte Rebalance Citrus Powder for Oral Solution

PA23180/023/002

Opella Healthcare France SAS T/A Sanofi
 Sodium chloride, potassium chloride, glucose & disodium hydrogen citrate  Manufacturing delays Date of shortage: 
September 2022

Expected return date: 
Q4 2023		 Last updated: 
17th October 2023 
Dioralyte Rebalance Natural Powder for Oral Solution

PA23180/023/003

Opella Healthcare France SAS T/A Sanofi
 Sodium chloride, potassium chloride, glucose & disodium hydrogen citrate  Manufacturing delays Date of shortage: 
September 2022

Expected return date: 
Awaiting update
 Last updated: 
15th March 2023
Dipentum 250mg Capsules

PA22657/001/001

Atnahs Pharma Netherlands B.V.
 Olsalazine
 Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early September 2022

Expected return date: 
Q3 2023 		 Last updated: 17th October 2022 
Dipentum 500mg Tablets

PA22657/001/002

Atnahs Pharma Netherlands B.V.
  Olsalazine
 Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
Early September 2022

Expected return date: 
Q3 2023 		 Last updated: 
17th October 2022 
Doxane XL 4mg Prolonged Release Tablets

PA0711/103/001

Rowex Ltd
  Doxazosin Unexpected increase in demand  Date of shortage: 
14th March 2023

Expected return date: 
April 2023 		 Last updated: 
15th March 2023 
Doxycycline Teva 100mg Hard Capsules

PA1986/081/001

Teva B.V.
 Doxycycline  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
Early March 2023

Expected return date: 
Early May 2023 		 Last updated: 
15th February 2023 
Duac Once Daily 10mg/g + 50mg/g Gel 30g

PA1077/120/001

GlaxoSmithKline (Ireland) Limited
 Clindamycin & Benzoyl peroxide
 Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
19th December 2022

Expected return date: 
2024 		 Last updated: 
19th December 2022 
Duloxetine 30mg Gastro-Resistant Capsules

PA2315/006/001

Accord Healthcare Ireland Ltd.
 Duloxetine Regulatory issue Date of shortage: 
Early February 2023

Expected return date: 
May 2023		 Last updated: 
18th January 2023
Duloxetine 60mg Gastro-Resistant Capsules

PA2315/006/002

Accord Healthcare Ireland Ltd.
 Duloxetine  Regulatory issue Date of shortage: 
Early February 2023

Expected return date: 
May 2023 		 Last updated: 
18th January 2023 
Dukoral

EU/1/03/263/002

Crucell Sweden AB
 Cholera vaccine Unexpected increase in demand 

(multiple countries affected) 		 Date of shortage: 
1st September 2022

Expected return date:
31st March 2023		 Last updated: 
23rd December 2022
Efavirenz Rowex 600mg Film-coated Tablets

PA0711/207/001

Rowex Ltd
  Efavirenz Manufacturing delay
 Date of shortage: 
9th February 2023

Expected return date:
Unknown at present  		 Last updated: 
15th February 2023 
Efient 10mg Tablets

EU/1/08/503/009

Substipharm
 Prasugrel  Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Week ending 26th March 2023

Expected return date: 
Week ending 2nd April 2023		 Last updated: 
8th March 2023 
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 

PharmaSwiss Ceska republika s.r.o.
 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 

PharmaSwiss Ceska republika s.r.o.
 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 

PharmaSwiss Ceska republika s.r.o.
 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Entecavir Accord 0.5mg Film Coated Tablets 

EU/1/17/1211/001

Accord Healthcare S.L.U.
  Entecavir Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
21st November 2022

Expected return date: 
July 2023		 Last updated: 
15th March 2023
Etoricoxib 60mg Film Coated Tablets

PA0711/232/002

Rowex Ltd
 Etoricoxib
 Manufacturing delay Date of shortage: 
Late August 2022

Expected return date:
July 2023		 Last updated: 
28th March 2023
Ezetimibe 10mg Tablets

PA2315/088/001

Accord Healthcare Ireland Ltd.
 Ezetimibe  Quality issue Date of shortage: 
October 2022

Expected return date: 
Unknown at present 		 Last updated: 
15th February 2023 
Ezetimibe Krka 10mg Tablets

KRKA, d.d., Novo mesto

PA1347/066/001
 Ezetimibe  Unexpected increase in demand  Date of shortage: 
Week ending 5th February 2023

Expected return date: 
Awaiting update		 Last updated; 
27th March 2023
Ezetimibe Rowa 10mg Tablets

PA0074/074/001

Rowa Pharmaceuticals Limited
 Ezetimibe  Manufacturing delay Date of shortage: 
31st January 2023 

Expected return date: 
April 2023		 Last updated: 
2nd February 2023 
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003

Rowex Ltd
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date:
Unknown at present		 Last updated: 
15th June 2022
Flector Tissugel 140mg Medicated Plaster

PA1104/004/001

IBSA Farmaceutici Italia S.r.l
  Diclofenac Distribution issue  Date of shortage: 
End of October 2022

Expected return date:
Unknown at present 		 Last updated: 
5th December 2022 
Flucloxacillin 1g Powder for Solution for Injection or Infusion

PA0281/122/003

Pinewood Laboratories Ltd
 Flucloxacillin
 Manufacturing delays Date of shortage: 
Week commencing 11th July 2022

Expected return date: 
Unknown at present		  Last updated: 
28th June 2022
Fludarabine Phosphate 25mg/ml Concentrate for Solution for Injection or Infusion

PA2315/035/001

Accord Healthcare Ireland Ltd.
 Fludarabine  API unavailability

(multiple markets affected) 		 Date of shortage: 
Early January 2023

Expected return date: 
Unknown at present 		 Last updated: 
18th January 2023 
Fluorouracil 25mg/ml Solution for Injection or Infusion

100ml presentation

PA0822/223/001

Pfizer Healthcare Ireland
 Fluorouracil  Quality issue

(multiple countries affected)		 Date of shortage:
25th February 2022

Expected return date: 
Late 2023		 Last updated: 
23rd February 2023

HCP letter
Fluorouracil 25mg/ml Solution for Injection or Infusion

20ml presentation

PA0822/223/001

Pfizer Healthcare Ireland
 Fluorouracil   Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Late January 2023

Expected return date: 
May 2023		 Last updated: 
23rd February 2023

HCP letter
Fluorouracil 50mg/ml Solution for Injection or Infusion

PA2315/091/001

Accord Healthcare Ireland Ltd.
  Fluorouracil Awaiting information  Date of shortage: 
15th February 2023

Expected return date: 
Week ending 18th June 2023		 Last updated: 
21st February 2023
Flutiform 125mcg/5mcg Pressurised Inhalation

PA1688/013/002

Mundipharma Pharmaceuticals Limited
 Fluticasone & formoterol
 Shipping delay

(multiple countries affected) 		 Date of shortage: 
Week ending 5th March 2023

Expected return date: 
Awaiting update		 Last updated:
28th March 2023
Fortum 500mg powder for solution for injection or infusion

PA23311/001/001

Sandoz Pharmaceuticals d.d.
  Ceftazidime Unexpected increase in demand  Date of shortage: 
Week ending 5th March 2023

Expected return date: 
May 2023		 Last updated: 
1st March 2023
Fortum 1g Powder for Solution for Injection or Infusion

PA23311/001/002

Sandoz Pharmaceuticals d.d.
  Ceftazidime Unexpected increase in demand  Date of shortage:
Late January 2023

Expected return date: 
May 2023		 Last updated: 
1st March 2023
Fortum 2g powder for solution for injection or infusion

PA23311/001/003

Sandoz Pharmaceuticals d.d.		 Ceftazidime Unexpected increase in demand  Date of shortage:
Early February 2023

Expected return date:
May 2023		 Last updated: 
1st March  
Frovex 2.5mg Film Coated Tablets

PA0865/009/001

Menarini International Operations Luxembourg S.A.
  Frovatriptan Quality issue

(multiple countries affected)		 Date of shortage: 
11th January 2022 

Expected return date: 
September 2023		  Last updated:
23rd September 2022
Fucidin 20 mg/g Ointment

PA0046/004/008

Leo Laboratories Limited
 Sodium Fusidate 
 Unexpected increase in demand Date of shortage: 
24th March 2023

Expected return date:
Week ending 16th April 2023		 Last updated: 
27th March 2023 
Furosemide 20mg in 2ml Solution for Injection

PA0073/059/004

Mercury Pharmaceuticals (Ireland) Ltd
 Furosemide Unexpected increase in demand  Date of shortage:
4th January 2023

Expected return date: 
April 2023 		 Last update: 
2nd February 2023 
Gabin 100mg Capsules

PA1445/020/001

Aurobindo Pharma (Malta) Limited
 Gabapentin   Unexpected increase in demand Date of shortage: 
13th January 2023

Expected return date: 
June 2023		 Last updated: 
1st March 2023
Ganfort Eye Drops

EU/1/06/340/004

AbbVie Deutschland GmbH & Co. KG
 Bimatoprost & timolol
 Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
Week ending 12th March 2023

Expected return date:
Week ending 2nd April 2023		 Last updated: 
27th March 2023 
Genotropin MiniQuick 1.0 mg Powder and Solvent for Solution for Injection

PA0822/128/003

Pfizer Healthcare Ireland
  Somatropin Manufacturing delay  Date of shortage: 
11th January 2023

Expected return date: 
Awaiting update		 Last updated: 
31st January 2023 
Germentin 125mg/31.25mg per 5ml Powder for Oral Suspension

PA0577/034/002

McDermott Laboratories Ltd., T/A Gerard Laboratories
 Amoxicillin & clavulanic acid
 Unexpected increase in demand 

(multiple countries affected) 		 Date of shortage: 
Week ending 12th February 2023

Expected return date:
May 2023 		 Last updated: 
30th January 2023
Germentin 500 mg/125 mg Film Coated Tablets

PA0577/034/001

McDermott Laboratories Ltd., T/A Gerard Laboratories
 Amoxicillin & clavulanic acid  Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
22nd December 2022

Expected return date: 
May 2023 		 Last updated: 
20th December 2022 
Gerax 250mcg Tablets

PA1445/024/001

Aurobindo Pharma (Malta) Limited
 Alprazolam Manufacturing delay  Date of shortage: 
End of February 2023

Expected return date:
June 2023 		 Last updated: 
7th March 2023 
Gerax 500mcg Tablets

PA1445/024/002

Aurobindo Pharma (Malta) Limited
 Alprazolam  Manufacturing delays  Date of shortage: 
July 2022

Expected return date: 
June 2023		 Last updated: 
8th February 2023
Glytrin 400 mcg per Metered dose Sublingual Spray

PA22906/002/001

Ayrton Saunders (Ireland) Limited
  Glyceryl trinitrate Manufacturing delay

(multiple countries affected)		 Date of shortage: 
November 2022

Expected return date:
May 2023		 Last updated: 
13th February 2023
Golden Eye 0.1% w/v Eye Drops

PA22695/001/001

Cambridge Healthcare Ireland Limited
 Propamidine   Regulatory issue

(multiple countries affected)		 Date of shortage: 
16th November 2022

Expected return date: 
Q2 2023		 Last updated; 
24th November 2022 
Golden Eye 0.15% w/w Eye Ointment

PA22695/001/002

Cambridge Healthcare Ireland Limited
 Dibromopropamidine  Manufacturing delays

(multiple countries affected) 		 Date of shortage: 
16th November 2022

Expected return date: 
Early 2024 		 Last updated: 
24th November 2022 
Gonal-F 75IU Powder and Solvent for Solution for Injection 

EU/1/95/001/025

Merck Europe B.V.
 Follitropin alfa  Manufacturing delay  Date of shortage: 
1st March 2023

Expected return date: 
Week ending 2nd April 2023 		 Last updated: 
28th February 2023 
Gyno-Pevaryl Once 150mg Vaginal Pessary

PA22650/006/001

KARO PHARMA AB
 Econazole nitrate
 Manufacturing delays  Date of shortage: 
March 2022

Expected return date: 
Unknown at present 		 Last updated: 
9th March 2022 
Heparin Sodium BP 2000 IU/l in 0.9 % w/v Sodium Chloride IV infusion

PA2299/014/002

Baxter Holding B.V.		 Heparin, citric acid, disodium phosphate dodecahydrate &  sodium chloride
 Awaiting information Date of shortage: 
3rd March 2023

Expected return date: 
Week ending 2nd April 2023		 Last updated: 
23rd March 2023 
Hydrea 500mg Hard Capsules

PA2239/021/001


CHEPLAPHARM Arzneimittel GmbH
 Hydroxycarbamide  Manufacturing delay Date of shortage: 
15th December 2022

Expected return date: 
Week ending 16th April 2023		 Last updated: 
20th March 2023
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 

Ethypharm
 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
Unknown at present 		 Last updated:
25th July 2022
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 

Ethypharm
 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
Unknown at present		 Last updated:
25th July 2022
Hytrin 5mg Tablets

PA1142/005/003

Amdipharm Limited
 Terazosin  Quality issue  Date of shortage:
22nd December 2022

Expected return date: 
Unknown at present 		 Last updated:
8th February 2023 
Ikervis 1 mg/ml Eye Drops

EU/1/15/990/001

Santen OY		 Ciclosporin  Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Early April 2023

Expected return date: 
Week ending 21st May 2023		 Last updated: 
27th March 2023 
Irbesartan Rowa 300mg Tablets

PA0074/080/003

Rowa Pharmaceuticals Limited
 Irbesartan  Manufacturing delay Date of shortage: 
31st January 2023

Expected return date: 
Week ending 21st May 2023		 Last updated: 
28th March 2023 
Ivemend 150mg Powder for Solution for Infusion

EU/1/07/437/003

Merck Sharp & Dohme Ltd
 Fosaprepitant
 Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
End of January 2023

Expected return date: 
June 2023		 Last updated: 
10th January 2023 

HCP letter
Ixprim 37.5 mg/325mg Effervescent Tablets

PA2242/006/002

Grunenthal Pharma Ltd
 Paracetamol & tramadol 
 Unexpected increase in demand Date of shortage: 
2nd November 2022

Expected return date: 
Awaiting update		 Last updated: 
28th February 2023
Januvia 50mg Film Coated Tablets

EU/1/07/383/008

Merck Sharp & Dohme BV
 Sitagliptin  Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Beginning of April 2023

Expected return date: 
Week ending 4th June 2023		 Last updated: 
13th March 2023 
Keflex 250mg Hard Capsules

PA1226/002/001

Flynn Pharma Limited
 Cephalexin  Unexpected increase in demand  Date of shortage: 
Early March 2023

Expected return date: 
Awaiting update		 Last updated: 
27th March 2023 
Keflex 125mg/5ml Powder for Oral Suspension

PA1226/002/002

Flynn Pharma Limited
  Cephalexin  Unexpected increase in demand Date of shortage: 
Early March 2023

Expected return date: 
May 2023		 Last updated: 
6th March 2023 
Keflex 250mg/5 ml Powder for Oral Suspension

PA1226/002/003

Flynn Pharma Limited
  Cephalexin 
 Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
Early January 2023

Expected return date:
April 2023 		 Last updated: 
3rd January 2023 
Klacid Forte 500mg Tablets

PA2010/004/002

Mylan IRE Healthcare Limited
 Clarithromycin Unexpected increase in demand Date of shortage: 
16th March 2023

Expected return date: 
Week ending 21st May 2023		 Last updated:
20th March 2023 
Klacid 250mg/5ml Granules for Oral Suspension

PA2010/004/006

Mylan IRE Healthcare Limited
  Clarithromycin Unexpected increase in demand  Date of shortage: 
Week ending 5th February 2023

Expected return date: 
Week ending 9th April 2023		 Last updated: 
23rd January 2023
Klacid IV 500mg Powder for Concentrate for Solution for Infusion

PA2010/004/003

Mylan IRE Healthcare Limited
  Clarithromycin   Unexpected increase in demand Date of shortage: 
8th February 2023

Expected return date: 
Awaiting update		 Last updated: 
28th March 2023
Klaram LA 500 mg Prolonged Release Tablets

PA2315/133/001

Mylan IRE Healthcare Limited
 Clarithromycin  Unexpected increase in demand Date of shortage: 
28th November 2022

Expected return date: 
Awaiting update		 Last updated: 
28th March 2023
Kopen 250mg Tablets

PA0298/007/001

Athlone Laboratories Ltd
 Phenoxymethylpenicillin 
 Unexpected increase in demand Date of shortage: 
Late April 2022

Expected return date: 
April 2023		 Last updated:
17th January 2023
Kopen Sugar Free 125mg/5ml Powder for Oral Solution

PA0298/007/002

Athlone Laboratories Ltd
 Phenoxymethylpenicillin 
 Unexpected increase in demand  Date of shortage: 
1st April 2022

Expected return date:
April 2023		 Last updated:
17th January 2023
Kopen Sugar Free 250mg/5ml Powder for Oral Solution

PA0298/007/003

Athlone Laboratories Ltd
 Phenoxymethylpenicillin 
 Unexpected increase in demand Date of shortage: 
1st April 2022

Expected return date: 
April 2023		 Last updated: 
17th January 2023
Lecalpin 10mg Film-Coated Tablets

PA2315/186/001

Accord Healthcare Ireland Ltd.
  Lercanidipine Unexpected increase in demand Date of shortage: 
Week ending 26th February 2023

Expected return date:
Unknown at present 		  
Last updated: 
6th March 2023
Lecalpin 20mg Film-Coated Tablets

PA2315/186/002

Accord Healthcare Ireland Ltd.
 Lercanidipine Unexpected increase in demand  Date of shortage: 
Early February 2023

Expected return date: 
Unknown at present 		 Last updated: 
13th March 2023
Lercanidipine Clonmel 20mg Film Coated Tablets

PA0126/187/002

Clonmel Healthcare Ltd		 Lercanidipine API unavailability   Date of shortage: 
Week ending 26th March 2023

Expected return date: 
Early May 2023		 Last updated: 
21st  March 2023
Leucovorin-Teva 10mg/ml Concentrate for Solution for Infusion

PA0749/001/001

Teva Pharma B.V.
 Folinic acid
 Unexpected increase in demand Date of shortage: 
21st February 2023

Expected return date: 
Week ending 2nd April 2023		 Last updated: 
17th February 2023 
Lopid 300mg Capsules

PA0822/014/001

Pfizer Healthcare Ireland
 Gemfibrozil  Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Week ending 12th February 2023

Expected return date: 
Week ending 23rd April 2023 		 Last updated: 
25th January 2023 
Lyclear 5% w/w Dermal Cream

PA1077/066/001

GlaxoSmithKline (Ireland) Limited
 Permethrin
 Manufacturing delay 

(multiple countries affected)		 Date of shortage:
Week ending 26th March 2023

Expected return date: 
Week ending 23rd April 2023		 Last updated: 
16th March 2023 
Lyrica 50mg Capsules

EU/1/04/279/009

Upjohn EESV
 Pregabalin
 Shipping delay  Date of shortage: 
23rd November 2022

Expected return date: 
Week ending 26th March 2023		 Last updated: 
9th March 2023
Marcain 0.25% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/001

Aspen Pharma Trading Limited		 Bupivacaine & adrenaline
 Manufacturing delay  Date of shortage: 
Late January 2023

Expected return date: 
August 2023 		 Last updated; 
30th January 2023
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002

Aspen Pharma Trading Limited
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
August 2023
 Last updated: 
30th January 2023
Maxilief Effervescent Tablets


PA0126/113/001

Clonmel Healthcare Ltd
 Paracetamol, Codeine & Caffeine
 Manufacturing delays Date of shortage: 
18th October 2022

Expected return date:
Week ending 9th April 2023		 Last updated: 
23rd March 2023
Medispray Oromucosal Spray

PA0126/300/001

Clonmel Healthcare Ltd
 Lidocaine & chlorhexidine  Unexpected increase in demand  Date of shortage: 
 Week commencing 14th November 2022

Expected return date: 
Late April 2023		 Last updated: 
7th December 2022 
Mefac 250mg Capsule

PA0074/015/001 

Rowa Pharmaceuticals Limited
 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Menopur 75IU Powder and Solvent for Solution or Injection

PA1009/015/001

Ferring Ireland Ltd
 Menotrophin  Quality issue

(multiple countries affected) 		 Date of shortage: 
Week commencing 31st October 2022

Expected return date:
Unknown at present		 Last updated:
4th November 2022 
Menopur 600IU Powder and Solvent for Solution or Injection

PA1009/015/002

Ferring Ireland Ltd
  Menotrophin Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 31st October 2022

Expected return date:
Unknown at present
 Last updated:
4th November 2022
Menopur 1200IU Powder and Solvent for Solution or Injection

PA1009/015/003

Ferring Ireland Ltd
  Menotrophin Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 31st October 2022

Expected return date:
Unknown at present
 Last updated: 
4th November 2022
Metalyse 50mg Powder and Solvent for Solution for Injection

EU/1/00/169/006

Boehringer Ingelheim International GmbH
Tenecteplase		 Manufacturing delays

(multiple countries affected) 		 Date of shortage: 
29th July 2022 2022

Expected return date: 
2024		 Last updated: 
23rd September 2022

HCP letter
Metformin Aurobindo 1000mg Film Coated Tablets

PA1445/021/003

Aurobindo Pharma (Malta) Limited
 Metformin  Awaiting information  Date of shortage: 
14th March 2023

Expected return date: 
May 2023 		 Last updated: 
15th March 2023 
Methotrexate 2.5mg Tablets

PA2315/062/001

Accord Healthcare Ireland Ltd.
 Methotrexate  Unexpected increase in demand   Date of shortage: 
5th December 2022

Expected return date: 
August 2023		 Last updated: 
28th November 2022 
Methylthioninium Chloride Proveblue 5mg/ml solution for Injection

EU/1/11/682/001

Provepharm SAS
 Methylthionium Regulatory issue  Date of shortage:
Week commencing 3rd October 2022

Expected return date: 
Late 2023		 Last updated: 
16th February 2023
Migraleve Film- Coated Tablets

PA0330/030/003

Johnson & Johnson (Ireland) Limited
 Buclizine, paracetamol & codeine
 Awaiting information  Date of shortage:
Late  February 2023

Expected return date: 
Awaiting update		 Last updated: 
28th March 2023
Milrinone 1 mg/ml Solution for Injection/Infusion

PA0281/244/001

Pinewood Laboratories Ltd
 Milrinone Distribution issue  Date of shortage:
16th November 2022

Expected return date: 
September 2023
 Last updated: 
8th March 2023
Minims Proxymetacaine hydrochloride 0.5% w/v, Eye Drops, Solution

PA23259/020/001

Bausch + Lomb Ireland Limited
  Proxymetacaine Manufacturing delay  Date of shortage: 
Late January 2023

Expected return date: 
Awaiting update		 Last updated: 
24th March 2023
Mirap 15mg Film-Coated Tablets 

PA0711/062/001

Rowex Ltd
 Mirtazapine  Manufacturing delay Date of shortage: 
End January 2023

Expected return date: 
Early April 2023		 Last update: 
16th March 2023
Mirtazapine 15mg Film-Coated Tablets

PA2315/072/001

Accord Healthcare Ireland Ltd.
 Mirtazapine Manufacturing delay Date of shortage: 
Week ending 12th March 

Expected return date: 
Early April 2023 		 Last updated: 
6th March 2023 
Mivacron 2mg/ml Solution for Injection

PA1691/031/001 

Aspen Pharma Trading Limited
 Mivacurium chloride
 Manufacturing delays Date of shortage: 
20th June 2022

Expected return date: 
Awaiting update		 Last updated: 
28th March 2023
Mometasone 50mcg dose, Nasal spray

PA0711/196/001

Rowex Ltd
 Mometasone  Awaiting information  Date of shortage: 
31st January 2023

Expected return date: 
July 2023		 Last updated: 
16th March 2023
Moviprep Orange Powder for Oral Solution

PA1336/001/002

Norgine B.V.
  Various Unexpected increase in demand

(multiple countries affected) 		 Date of shortage: 
Mid November 2022

Expected return date: 
February 2023		 Last updated: 
20th December 2022 
Naloxone Hydrochloride 400 micrograms/ml Solution for Injection or Infusion

PA0073/111/002

Mercury Pharmaceuticals (Ireland) Ltd
  Naloxone Unexpected increase in demand  Date of shortage:
23rd January 2023

Expected return date: 
Awaiting update		 Last updated: 
24th March 2023
Nebivolol Teva 5 mg Tablets

PA0749/078/001

Teva Pharma B.V.
  Nebivolol Manufacturing delay

(multiple countries impacted)		 Date of shortage: 
21st February 2023

Expected return date: 
Early April 2023 		 Last updated: 
7th February 2023 
Neurontin 100mg Capsules

PA23055/004/001

Upjohn EESV
 Gabapentin  Unexpected increase in demand Date of shortage: 
Week ending 12th February 2023

Expected return date: 
Week ending 9th April 2023		 Last updated: 
23rd February 2023 
Neurostil 100mg Capsules

PA0749/164/001

Teva Pharma B.V.
  Gabapentin Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Mid March 2023

Expected return date:
Week ending 23rd April 2023		 Last updated: 
16th March 2023
Neurostil 300mg Capsules

PA0749/164/001

Teva Pharma B.V.

 Gabapentin  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
20th March 2023

Expected return date:
Week ending 23rd April 2023		 Last updated: 
6th March 2023
Neurostil 400mg Capsules

PA0749/164/001

Teva Pharma B.V.
  Gabapentin  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
20th March 2023

Expected return date:
Week ending 23rd April 2023
 Last updated: 
6th March 2023
Nicorette 15mg Inhaler 

4 pack 

PA0330/037/010

Johnson & Johnson (Ireland) Limited
 Nicotine Unexpected increase in demand  Date of shortage: 
End of November 2022

Expected return date: 
Awaiting update		 Last updated:  
24th February 2023
Night Nurse Cold Remedy Oral Solution

PA0678/014/001

GlaxoSmithKline Consumer Healthcare (Ireland) Limited 
 Paracetamol, promethazine & dextromethorphan
 Unexpected increase in demand 

(multiple countries affected)		 Date of shortage:
19th December 2022

Expected return date: 
Week ending 14th May 2023		 Last updated: 
24th March 2023
Noradrenaline (Norepinephrine) 1:1000 Concentrate For Solution For Infusion

PA0822/219/001 

Pfizer Healthcare Ireland
  Noradrenaline  Quality issue Date of shortage: 
24th March 2023

Expected return date: 
Week ending 9th April 2023 		 Last updated: 
27th March 2023 

HCP letter 
Nurofen for Children Six Plus Orange 200 mg/5ml Oral Suspension

(200ml presentation only)

PA0979/056/001

Reckitt Benckiser Ireland Ltd
  Ibuprofen  Unexpected increase in demand Date of shortage: 
17th February 2023

Expected return date: 
End of April 2023 		 Last updated: 
17th February 2023 
Nurofen for Children Six Plus Strawberry 200mg/5ml Oral Suspension

PA0979/056/002

Reckitt Benckiser Ireland Ltd
 Ibuprofen   Unexpected increase in demand Date of shortage: 
End of December 2022

Expected return date:
End of April 2023		 Last updated: 
15th February 2023
Olmesartan medoxomil 10mg Film Coated Tablets

PA0577/214/001

McDermott Laboratories Ltd., T/A Gerard Laboratories
 Olmesartan  Unexpected increase in demand  Date of shortage: 
Week ending 26th February 2023

Expected return date: 
Week ending 30th July 2023 		 Last updated: 
20th February 2023 
Olmesartan Medoxomil 10mg Film-Coated Tablets

PA2315/113/001

Accord Healthcare Ireland Ltd.
 Olmesartan Unexpected increase in demand   Date of shortage:
Week ending 12th March 2023

Expected return date: 
Unknown at present 		 Last updated: 
24th February 2023 
Olmesartan medoxomil 20mg Film Coated Tablets

PA0577/214/002

McDermott Laboratories Ltd., T/A Gerard Laboratories
  Olmesartan Unexpected increase in demand  Date of shortage: 
26th January 2023

Expected return date: 
Week ending 14th May 2023 		 Last updated: 
30th January 2023 
Olmesartan Rowex 10mg Tablets

PA0711/255/001

Rowex Ltd
  Olmesartan  Awaiting information Date of shortage: 
14th March 2023

Expected return date: 
Week ending 30th April 2023		 Last updated: 
15th March 2023 
Omeprazole Pinewood 20mg Gastro Resistant Tablets

PA0281/152/001

Pinewood Laboratories Ltd
  Omeprazole API unavailability   Date of shortage: 
20th March 2023

Expected return date:
Week ending 21st May 2023		 Last updated: 
21st March 2023
Opticrom Allergy Single Dose 2% w/v Eye Drops, Solution

PA23180/010/003

Opella Healthcare France SAS T/A Sanofi
 Sodium cromoglicate
 Quality issue

(multiple countries affected)		 Date of shortage: 
27th January 2022 

Expected return date:
Week ending 21st May 2023		 Last updated: 
27th March  2023
Opticrom allergy 2% w/v Eye Drops

PA23180/010/002

Opella Healthcare France SAS T/A Sanofi
 Sodium cromoglicate
 Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
16th January 2023

Expected return date: 
April 2023
 Last updated: 
23rd January 2023 
Otrivine Adult Menthol 0.1% w/v Nasal Spray, Solution

PA0678/120/004

GlaxoSmithKline Consumer Healthcare (Ireland) Limited 
 Xylometazoline
 Unexpected increase in demand 

(multiple countries affected)
 Date of shortage; 
December 2022

Expected return date: 
Week ending 23rd April 2023		 Last updated: 
24th March 2023 
Otrivine Congestion Relief 0.1% w/v Nasal Spray, Solution

PA0678/120/005

GlaxoSmithKline Consumer Healthcare (Ireland) Limited 
 Xylometazoline
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
10th December 2022

Expected return date: 
Week ending 23rd April 2023		 Last updated:
24th March 2023 
Otrivine Congestion Relief Menthol 0.1% w/v Nasal Spray

PA0678/120/002

GlaxoSmithKline Consumer Healthcare (Ireland) Limited 
 Xylometazoline
 Unexpected increase in demand

(multiple countries affected) 		 Date of shortage: 
9th January 2023

Expected return date; 
Week ending 16th April 2023		 Last updated: 
14th March 2023
Otrivine Extra Dual Relief 0.5mg/ml + 0.6mg/ml Nasal Spray

PA0678/131/001

GlaxoSmithKline Consumer Healthcare (Ireland) Limited 
 Xylometazoline & ipratropium bromide  Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
Late October 2022

Expected return date: 
Week ending 30th April 2023		 Last updated: 
24th March 2023 
OxyContin 10mg Prolonged Release Tablets

PA1688/005/002

Mundipharma Pharmaceuticals Limited
  Oxycodone  Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Early February 2023

Expected return date: 
March 2023		 Last updated: 
24th January 2023 
OxyNorm Dispersa 5mg Orodispersible Tablets

PA1688/006/007

Mundipharma Pharmaceuticals Limited
 Oxycodone Unexpected increased demand  Date of shortage: 
Week ending 8th January 2022

Expected return date: 
Awaiting update		 Last updated: 
28th March 2023
Oxynorm Dispersa 10mg Orodispersible tablets 

PA1688/006/008

Mundipharma Pharmaceuticals Limited
  Oxycodone Manufacturing delay Date of shortage: 
21st November 2022 

Expected return date: 
Awaiting update
 Last updated: 
31st January 2023
OxyNorm Liquid 1mg/ml Oral Solution

PA1688/006/002

Mundipharma Pharmaceuticals Limited
  Oxycodone Shipping delay  Date of shortage: 
17th January 2023

Expected return date: 
Awaiting update		 Last updated: 
28th March 2023
Oxycodone hydrochloride 50mg/ml Solution for Injection or Infusion

PA0281/235/002

Pinewood Laboratories Ltd
 Oxycodone  Manufacturing delays   Date of shortage: 
1st November 2021 

Expected return date: 
Unknown at present		 Last updated: 
23rd August 2022
Palladone 1.3mg Capsules

PA1688/007/001

Mundipharma Pharmaceuticals Limited
  Hydromorphone Manufacturing delays Date of shortage:
Week commencing 8th August 2022

Expected return date: 
March 2023		 Last updated: 
17th February 2023
Pazenir 5 mg/ml Powder for Dispersion for Infusion

EU/1/18/1317/001

Ratiopharm GmbH
  Paclitaxel Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
12th January 2023

Expected return date: 
July 2023		 Last updated: 
25th January 2023 
Pergoveris (900 IU /450 IU)/1.44 mL Solution for injection

EU/1/07/396/006

Merck Europe B.V.
 Lutropin alfa & follitropin alfa  Unexpected increase in demand Date of shortage: 
Mid March 2023

Expected return date: 
Week ending 2nd April 2023 		 Last updated: 
16th March 2023 
Plavix 300mg Film-Coated Tablet

EU1/98/069/009

Sanofi Winthrop Industrie
 Clopidogrel Manufacturing delay Date of shortage: 
16th March 2023

Expected return date: 
Week ending 30th April 2023		 Last updated: 
24th March 2023 
Prasugrel Mylan 10mg Tablets

EU/1/18/1273/009

Mylan Pharmaceuticals Limited
 Prasurgel  Unexpected increase in demand Date of shortage: 
Week ending 19th March 2023

Expected return date: 
Week ending 23rd July 2023 		 Last updated:
1st March 2023 
Prednisolone 5mg Soluble Tablets

PA1142/034/001

Amdipharm Limited
 Prednisolone  API unavailability Date of shortage: 
27th March 2023

Expected return date: 
Unknown at present 		 Last updated: 
13th March 2023 
Prednisolone 20mg Rectal Foam

PA22643/003/001

Chemidex Pharma Limited
 Prednisolone  Manufacturing delay  Date of shortage: 
End of February 2023

Expected return date: 
April 2023 		 Last updated: 
14th February 2023 
Raporsin 8mg Prolonged Release Tablets

PA2315/005/001

Accord Healthcare Ireland Ltd.
 Doxazosin Awaiting information  Date of shortage: 
Week ending 5th March 2023

Expected return date: 
Awaiting update		 Last updated: 
28th March 2023
Risonate Once Weekly 35mg Film Coated Tablets

PA0749/064/001

Teva Pharma B.V.
 Risedronate    API unavailability 

(multiple countries affected)		 Date of shortage: 
Week commencing 27th June 2022

Expected return date: 
June 2023		 Last updated: 
6th January 2023
Ritalin LA 20mg Prolonged Release Capsules

PA1972/002/002

InfectoPharm Arzneimittel und Consilium GmbH
 Methylphenidate Manufacturing delay  Date of shortage: 
16th March 2023

Expected return date: 
14th April 2023		 Last updated: 
20th March 2023 
Rivotril 0.5mg Tablets

PA2239/020/001

CHEPLAPHARM Arzneimittel GmbH
 Clonazepam  Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
Week commencing 17th October 2022 

Expected return date: 
Week ending 2nd April 2023		 Last updated: 
20th March 2023
Roaccutane 20mg Soft Capsules

PA2307/007/002

Roche Products (Ireland) Ltd
  Isotretinoin Manufacturing delay Date of shortage: 
6th March 2023

Expected return date: 
Week ending 2nd April 2023		 Last updated: 
7th March 2023 
Sabril 500mg Film Coated Tablets

PA0540/023/001

Sanofi-Aventis Ireland Limited T/A SANOFI
 Vigabatrin
  API unavailability 

(multiple countries affected)		 Date of shortage: 
9th January 2023

Expected return date: 
Week ending 2nd April 2023		 Last updated: 
21st March 2023

HCP letter
Sandimmun 100mg Soft Capsules

PA0896/027/004

Novartis Ireland Limited
  Ciclosporin Quality issue

(multiple countries affected)		 Date of shortage: 
3rd February 2023

Expected return date: 
Awaiting update		 Last updated:
15th March 2023
Simbrinza Eye Drops

EU/1/14/933/001

Novartis Europharm Limited
 Brinzolamide & brimonidine  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
6th March 2023

Expected return date: 
Week ending 9th April 2023 		 Last updated: 
20th February 2023 
Six Plus Parapaed Paracetamol Oral Suspension 250mg/5ml

PA0281/002/003

Pinewood Laboratories Ltd
 Paracetamol Quality issue Date of shortage: 
January 2022 

Expected return date:
April 2023		 Last updated: 
21st November 2022
Solpadeine Soluble Tablets

12 pack

PA1186/011/001


Chefaro Ireland DAC
 Paracetamol, codeine & caffeine
 Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
Late January 2023

Expected return date:
Awaiting update		 Last updated: 
28th March 2023
Solpadeine Soluble Tablets

24 pack

PA1186/011/001

Chefaro Ireland DAC
 Paracetamol, codeine & caffeine  Manufacturing delay 

(multiple countries affected)		 Date of shortage:
Week ending 12th March 2023

Expected return date: 
Week ending 16th April 2023		 Last updated:
2nd March 2023 
Solpadeine Soluble Tablets

60 pack

PA1186/011/001

Chefaro Ireland DAC
 Paracetamol, codeine & caffeine
 Manufacturing delay 

(multiple countries affected) 
 Date of shortage: 
Late January 2023 

Expected return date: 
Unknown at present		  Last updated: 
23rd February 2023
Spasmonal 60mg Capsules

PA2010/043/001

Mylan IRE Healthcare Limited
 Alverine
 Manufacturing delay Date of shortage: 
23rd November 2022

Expected return date: 
Awaiting update		 Last updated: 
15th March 2023
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 

Ayrton Saunders (Ireland) Limited
 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
25th July 2022
Stemetil 12.5mg/ml Solution for Injection 

PA0540/127/002

Sanofi-Aventis Ireland Limited T/A SANOFI
 Prochlorperazine
  API unavailability 

(multiple countries affected)		 Date of shortage: 
Week ending 26th March 2023

Expected return date: 
Week ending 4th June 2023		 Last update: 
7th March 2023 
Sumatran 100mg Tablets

PA0711/081/002

Rowex Ltd
 Sumatriptan   Awaiting information Date of shortage: 
27th March 2023

Expected return date: 
May 2023 		 Last updated: 
28th March 2023 
Tambocor 100mg Tablets

PA2010/026/003

Mylan IRE Healthcare Limited
  Flecainide API unavailability 

(multiple countries affected) 		 Date of shortage: 
Week ending 19th February 2023

Expected return date:
Week ending 2nd April 2023 		 Last updated: 
13th February 2023 
Tamox 10mg Film-Coated Tablets

PA0711/022/001

Rowex Ltd
  Tamoxifen  Unexpected increase in demand Date of shortage: 
31st January 2023

Expected return date:
July 2023		 Last updated: 
16th March 2023
Tamoxifen 20mg Tablets

PA0577/207/001

McDermott Laboratories Ltd., T/A Gerard Laboratories
  Tamoxifen Manufacturing delays

(multiple countries affected)		 Date of shortage: 
16th January 2023

Expected return date: 
April 2023		 Last updated: 
19th January 2023 
Telmisartan/Hydrochlorothiazide Rowa 40mg/12.5mg Tablets

PA0074/081/001

Rowa Pharmaceuticals Limited
 Telmisartan & hydrochlorothiazide
 Awaiting information Date of shortage: 
14th March 2023

Expected return date: 
June 2023		 Last updated: 
16th March 2023 
Telmisartan/Hydrochlorothiazide Rowa 80mg/25mg Tablets

PA0074/081/001

Rowa Pharmaceuticals Limited
 Telmisartan & hydrochlorothiazide  Awaiting information  Date of shortage: 
14th march 2023

Expected return date: 
July 2023		 Last updated: 
16th March 2023 
Teveten Plus 600mg/12.5mg Film-Coated Tablets

PA2010/018/001

Mylan IRE Healthcare Limited
 Eprosartan & hydrochlorothiazide
 Manufacturing delay  Date of shortage: 
Week ending 19th February 2023

Expected return date: 
Week ending 16th April 2023 		 Last updated: 
7th February 2023 
Thamicarb 84mg/ml Oral Solution

PA22697/017/001

Syri Pharma Limited t/a Thame Laboratories
 Sodium hydrogen carbonate
 Unexpected increase in demand  Date of shortage: 
15th February 2023

Expected return date: 
Awaiting update		 Last updated: 
24th March 2023
Tipol 250mg Suppositories

PA0126/331/003

Clonmel Healthcare Ltd
 Paracetamol  Unexpected increase in demand Date of shortage: 
5th December 2023

Expected return date: 
11th April 2023 		 Last updated: 
10th January 2023 
Tobi 300mg/5ml Nebuliser Solution

PA2010/063/001

Mylan IRE Healthcare Limited
 Tobramycin
 Manufacturing delay  Date of shortage: 
23rd November 2022

Expected return date:
Week ending 9th April 2023		 Last updated: 
27th March 2023
Trandate 100mg Film-Coated Tablets

PA1638/006/002

RPH Pharmaceuticals AB
  Labetalol Manufacturing delay Date of shortage: 
16th February 2023 

Expected return date: 
Awaiting update		 Last updated: 
2nd March 2023
Trandate 200mg Film Coated Tablets

PA1638/006/003

RPH Pharmaceuticals AB
 Labetalol
 Manufacturing delay  Date of shortage: 
Early November 2022

Expected return date:
Awaiting update		 Last updated: 
2nd March 2023 
Trimoptin 100mg Tablets

PA0298/014/001

Athlone Laboratories Ltd
 Trimethoprim  Unexpected increase in demand Date of shortage: 
Late November 2022

Expected return date:
End of May 2023		 Last updated: 
20th March 2023
Trimoptin 200mg Tablets

PA0298/014/002

Athlone Laboratories Ltd
 Trimethoprim  Unexpected increase in demand  Date of shortage: 
Mid December 2022

Expected return date: 
End of May 2023		 Last updated: 
20th March 2023
Utrogestan Vaginal 200mg Vaginal Capsule

PA22624/001/001

Besins Healthcare Ireland Limited
 Progesterone  Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
21st March 2023

Expected return date: 
Week ending 18th June 2023 		 Last updated: 
23rd March 2023 
Valaciclovir 500mg Film-Coated Tablets

PA2315/102/001

Accord Healthcare Ireland Ltd.
 Valaciclovir
 API unavailability  Date of shortage:
Week commencing 26th September 2022

Expected return date: 
Awaiting update		 Last updated:
28th March 2023
Valsartan 160mg Film-Coated Tablets 

PA2315/188/003

Accord Healthcare Ireland Ltd.
 Valsartan  Manufacturing delay Date of shortage:
Mid January 2023 

Expected return date: 
September 2023		 Last updated: 
15th March 2023
Vedixal 75mg Tablets

PA0711/161/004

Rowex Ltd
 Venlafaxine
 Shipping delay  Date of shortage: 
27th March 2023

Expected return date:
April 2023 		 Last updated: 
28th March 2023 
Vidisic 0.2% Eye Gel

PA23259/008/001

Bausch + Lomb Ireland Limited
 Carbomer  Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
Q4 2022

Expected return date: 
Week ending 14th May 2023		 Last updated: 
2nd March 2023 
Vidisic Preservative Free Single Dose Unit

PA23259/008/002

Bausch + Lomb Ireland Limited
  Carbomer Manufacturing delay

(multiple countries affected) 
 Date of shortage: 
Q4 2022

Expected return date: 
Week ending 16th April 2023 		 Last updated: 
2nd March 2023 
Vividrin Preservative Free SDU 2% w/v Eye Drops solution

PA23259/005/002

Bausch + Lomb Ireland Limited
 Sodium cromoglycate
 Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
Q4 2022

Expected return date: 
Week ending 21st May 2023
 Last updated: 
2nd March 2023 
Warfant 1mg Tablets

PA0073/139/001

Mercury Pharmaceuticals (Ireland) Ltd
 Warfarin  API unavailability  Date of shortage: 
End September 2022

Expected return date: 
Unknown at present		 Last updated: 
7th February 2023
Warfant 3 mg Tablets

PA0073/139/002

Mercury Pharmaceuticals (Ireland) Ltd
 Warfarin  API unavailability  Date of shortage: 
27th January 2023

Expected return date: 
Unknown at present 		 Last updated:
7th February 2023
Xanax 250mcg Tablets

PA23055/010/002

Upjohn EESV
 Alprazolam  Shipping delay  Date of shortage: 
Late January 2023

Expected return date: 
Awaiting update		 Last updated: 
28th March 2023
Xermelo 250mg Film Coated Tablets

EU/1/17/1224/001

Serb S.A.S.		 Telotristat  Manufacturing delay

(multiple countries affected)		 Date of shortage: 
Early March 2023

Expected return date: 
Q3 2023 		 Last updated: 
20th February 2023 
Xylocaine 2% with Adrenaline

PA1691/027/001

Aspen Pharma Trading Limited
 Adrenaline & Lidocaine
 Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
15th March 2023

Expected return date: 
Week ending 6th August 2023 		 Last updated: 
6th March 2023 
Zanidip 10mg Film-Coated Tablets

PA0812/001/001

Recordati Industria Chimica e Farmaceutica SpA
  Lercanidipine Unexpected increase in demand Date of shortage: 
Late January 2023

Expected return date: 
Awaiting update		 Last updated: 
20th March 2023
Zanidip 20mg Film-Coated Tablets

PA0812/001/002

Recordati Industria Chimica e Farmaceutica SpA
  Lercanidipine  Unexpected increase in demand Date of shortage:
6th March 2023

Expected return date: 
Awaiting update		 Last updated: 
28th March 2023 
Zerseos 05 mg/25 mg per 2.5 ml Nebuliser Solution

PA22871/011/001

Azure Pharmaceuticals Ltd
 Ipratropium & salbutamol
 Manufacturing delay Date of shortage: 
Week ending 5th February 2023 

Expected return date: 
March 2023		 Last updated: 
17th January 2023 
Zindaclin 1% Gel

PA23139/001/001

Canute Pharma (Ireland) Limited
 Clindamycin   Distribution issue Date of shortage: 
December 2022

Expected return date: 
Unknown at present		 Last updated: 
6th March 2023 
Zirtek 10mg Film Coated Tablets

PA0891/008/002

UCB (Pharma) Ireland Limited
 Cetirizine
 Unexpected increase in demand  Date of shortage: 
26th January 2023

Expected return date:
Awaiting update		 Last updated: 
20th March 2023
Zithromax Powder for Oral Suspension 200mg/5ml

(22.5ml presentation only)

Pfizer Healthcare Ireland
 Azithromycin Unexpected increase in demand 

(multiple markets affected)		 Date of shortage: 
16th March 2023

Expected return date: 
Week ending 28th May 2023		 Last updated: 
20th March 2023 

HCP letter
Zolepant 40mg Gastro-Resistant Tablets

PA0281/140/002

Pinewood Laboratories Ltd
 Pantoprazole  Unexpected increase in demand Date of shortage: 
3rd March 2023

Expected return date: 
August 2023		 Last updated: 
7th March 2023 
Zolmitriptan  2.5mg Orodispersible Tablets

PA2315/232/001

Accord Healthcare Ireland Ltd.
  Zolmitriptan API unavailability   Date of  shortage: 
Week commencing 31st October 2022

Expected return date: 
May 2023		 Last updated: 
15th March 2023
Zofran 4mg/5ml Syrup

PA0896/036/003

Novartis Ireland Limited
 Ondansetron  Manufacturing delay Date of shortage: 
Mid December 2022

Expected return date: 
May 2023		 Last updated:
7th December 2022 
Zostavax Powder and Solvent for Suspension for Injection in a Pre Filled Syringe

EU/1/06/341/011

Merck Sharp & Dohme BV
 Varicella-zoster virus, oka/merck strain (live attenuated)
 Unexpected increase in demand Date of shortage:
9th January 2023

Expected return date: 
May 2023		 Last updated: 
12th January 2023
Zyban 150mg Prolonged Release Tablets

PA1077/017/001

GlaxoSmithKline (Ireland) Limited
  Brupropion Quality issue

(multiple countries affected) 		 Date of shortage:
1st November 2022

Expected return date: 
Unknown at present 		 Last updated: 
7th November 2022 

Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL



Date of shortage: 
2nd July 2021

Expected return date: 
Unknown at present  
Date of shortage: 
2nd July 2021

Expected return date: 
Unknown at present  

Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 

Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abstral 100mcg Sublingual Tablets

PA2288/004/002
  Fentanyl  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
3rd September 2021 

Expected return date: 
Week commencing 1st October 2021		 Last updated: 
22nd October 2021
Abstral 200mcg Sublingual Tablets

PA2288/004/003
 Fentanyl Manufacturing delays 

(multiple countries affected)		 Date of shortage:
15th August 2021

Return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 300mcg Sublingual Tablets

PA2288/004/004
 Fentanyl  Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
5th October 2021

Expected return date: 
Week commencing 25th October 2021
 Last updated: 
22nd October 2021
Abstral 400mcg Sublingual Tablets

PA2288/004/005
 Fentanyl  Manufacturing delays 

(multiple countries affected)
 Date of shortage: 
4th October 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Abstral 600mcg Sublingual Tablets

PA2288/004/006
 Fentanyl   Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
2nd September 2021 

Expected return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 700mcg Sublingual Tablets

PA2288/004/007
 Fentanyl Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
2nd September 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Adizem-XL 180mg Prolonged Release Capsules

PA1688/001/005
 Dilitazem  Manufacturing delays Date of shortage: 
1st October 2021

Expected return date: 
November 2021 		 Last updated: 
27th September 2021
Amitriptyline 25mg Film Coated Tablets

PA0126/041/001
 Amitriptyline
 API unavailability Date of shortage: 
2nd September 2021 

Expected return date: 
Late October 2021		 Last updated: 
7th September 2021 

HCP letter
Astilin 10mg Tablets

PA23163/001/001
 Amitriptyline  Awaiting update Date of shortage: 
27th August 2021

Expected return date: 
29th October 2021		 Last updated: 
5th October 2021

HCP letter
Ativan 4mg/ml Solution for Injection

PA0822/090/002 		 Lorazepam  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2020

Expected return date:
Unknown at present		 Last updated:
14th May 2021 
 
HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
2022		 Last updated:
3rd February 2021
Bendroflumethiazide 2.5mg Tablets

PA22749/021/001
 Bendroflumethiazide
  Regulatory issue Date of shortage:
3rd September 2021

Expected return date: 
Awaiting update		 Last updated: 
1st October 2021
Beromun 1mg Powder for Solution for Infusion

EU/1/99/097/001 		 Tasonermin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
December 2020

Expected return date:
November 2021		 Last updated:
1st June 2021
Calcium Acetate 500mg Tablets

PA0281/063/001
 Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
Late December 2021		 Last updated: 
30th September 2021
Canesten HC 1% w/w + 1% w/w Cream

PA1410/040/002
 Clotrimazole & Hydrocortisone  Manufacturing delays Date of shortage: 
30th September 2021 

Expected return date:
5th November 2021		 Last updated: 
22nd September 2021
Catapres Tablets 100mcg

PA2256/003/001
  Clonidine Manufacturing delays

(multiple countries affected)		 Date of shortage: 
25th July 2021

Expected return date: 
25th October 2021		 Last updated: 
21st June 2021 
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution

PA2299/005/001
 Chlorhexidine acetate & cetrimide
 Unexpected increase in demand Date of shortage: 
September 2021 

Expected return date: 
Mid November 2021 		 Last updated: 
20th October 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution

PA0281/124/001 		 Chlorpromazine hydrochloride  Manufacturing delays  Date of shortage:
End of February 2021

Expected return date:
End January 2022		 Last updated:
5th October 2021
 
HCP letter
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes 

PA0540/097/008
 Enoxaparin sodium  API unavailability   Date of shortage: 
22nd October 2021 

Expected return date: 
Unknown at present		 Last updated: 
13th October 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion

PA1457/001/001
 Amoxicillin & Clavulanic acid
 Manufacturing delays Date of shortage: 
13th October 2021 

Expected return date: 
Awaiting update		 Last updated: 
18th October 2021 
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion

PA1457/001/002		 Amoxicillin & clavalunic acid Unexpected increase in demand Date of shortage:
5th February 2020

Expected return date:
Awaiting update
 Last updated:
19th October 2021
CoAprovel 300mg/12.5mg Tablets

EU/1/98/086/004
 Irbesartan & Hydrochlorothiazide  Shipping delay  Date of shortage: 
5th November 2021

Expected return date: 
Late November 2021  		 Last updated: 
22nd October 2021 
Cyklokapron 100 mg/mL Solution for Injection/Infusion

PA0822/117/001
 Tranexamic acid Manufacturing delays Date of shortage: 
Week commencing 18th October 2021

Expected return date: 
Week commencing 15th November 2021 		 Last updated: 
5th October 2021 
Deslor 5mg Film Coated Tablets

PA0711/202/001
 Desloratidine Awaiting information   Date of shortage: 
19th September  2021  

Expected return date: 
Late December 2021		 Last updated: 
October 2021 
Desmopressin 100mcg/ml Nasal Drop Solution

PA1009/001/001 		 Desmopressin  Manufacturing delays due to quality issue

(multiple countries affected) 		 Date of shortage:
Mid December 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Dioralyte Blackcurrant Powder for Oral Solution (20 pack)

PA0540/098/001
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate  Unexpected increase in demand  Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021		 Last updated: 
30th September 2021
Dioralyte Citrus Powder for Oral Solution
(20 pack)

PA0540/098/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution
(6 pack)

PA0540/194/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Doxatan 4mg Tablets

PA0126/202/003 		 Doxazosin  Manufacturing delay   Date of shortage: 
4th October 2021

Expected return date:
Week commencing 1st November 2021		 Last updated: 
20th October 2021
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005		 Phenytoin Manufacturing delays

(multiple countries affected)		 Date of shortage:
Early November 2019

Expected return date:
Unknown at present		 Last updated:
4th June 2020
 
HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion

PA1852/002/001 		 Esomeprazole  Unavailability of API  Date of shortage:
Early October 2020

Expected return date:
Late November 2021		 Last updated:
12th October 2021
Ezetimibe Rowa 10mg Tablets

PA0074/074/001
 Ezetimibe Awaiting information  Date of shortage: 
19th October 2021 

Expected return date: 
Late November 2021 		 Last updated: 
21st October 2021
Ezetimibe Teva 10mg tablets

PA1986/012/001
 Ezetimibe  Quality Issue  Date of shortage: 
18th October 2021 

Expected return date: 
13th December 2021		 Last updated: 
4th October 2021
Ezetimibe 10mg tablets

PA0577/198/001
 Ezetimibe
 Manufacturing delays  Date of shortage: 
Late August 2021 

Expected return date: 
Early November 2021		 Last updated: 
4th October 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets

PA0711/262/001
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 22nd July 2021

Expected return date: 
October 2021		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date: 
End November 2021
 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets

PA1986/067/003
 Ezetimibe & simvastatin
 API unavailability

(multiple countries impacted) 		 Date of shortage: 
30th August 2021 

Expected return date: 
Awaiting update		 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets

PA0126/281/002
Ezetimibe & simvastatin
 Manufacturing delays   Date of shortage: 
Week commencing 20th September 2021

Expected return date: 
Unknown at present		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets

PA0126/281/004
 Ezetimibe & simvastatin
 Manufacturing delays Date of shortage: 
Week commencing 20th September 2021

Expected return date:  
Unknown at present		 Last updated: 
20th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection

PA0822/198/002
 Folinic Acid  Unexpected increase in demand Date of shortage: 
Week commencing 27th September 2021

Expected return date: 
Awaiting update		 Last updated:
18th October 2021
Fomicyt 40mg/ml Powder for Solution for Infusion

PA1972/001/001
 Fosfomycin sodium Regulatory issue  Date of Shortage: 
October 2021 

Expected return date: 
Unknown at present		 Last updated: 
12th October 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension

PA1142/014/001
 Gentamicin & Hydrocortisone Unavailability of API 

(multiple countries affected)		 Date of shortage: 
23rd August 2021

Expected return date:
Late November 2021		 Last updated: 
9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Imodium Plus 2mg/125mg Tablets

PA0330/050/001
 Loperamide & simeticone  Manufacturing delay  Date of shortage: 
11th October 2021 

Expected return date:
Week commencing 22nd November 2021		 Last updated: 
20th October 2021
Innohep 10,000 IU/ml Solution for Injection

PA0046/060/002
 Tinzaparin sodium
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
20th September 2021

Expected return date: 
Mid-November 2021
 Last updated: 
23rd September 2021
Instanyl 50mcg Nasal Spray 

EU/1/09/531/010-013
 Fentanyl  Quality issue 
(multiple countries affected)		 Date of shortage: 
1st August 2021 

Expected return date: 
February 2022
 Last updated: 
20th August 2021
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated: 
20th August 2021
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated:
20th August 2021
Invokana 300mg Film Coated Tablets

EU/1/13/884/005-008		 Canagliflozin
 Unexpected increase in demand  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021 		 Last updated: 
12th October 2021
Letrozole 2.5mg Film Coated Tablets

PA2315/109/001
 Letrozole  Awaiting information   Date of shortage: 
Week commencing 25th October 2021

Expected return date: 
End November 2021		 Last updated: 
18th October 2021 
Letrozole 2.5mg Film Coated Tablets

PA0126/198/001
 Letrozole  Manufacturing delays  Date of shortage: 
22nd October 2021 

Expected return date: 
22nd December 2021		 Last updated: 
18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets

PA0749/085/001
 Letrozole  API unavailability 

(multiple countries affected) 		 Date of shortage: 
Week commencing 9th August 2021

Expected return date: 
January 2021		 Last updated: 
5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet

PA0711/051/002 		 Lisinopril & Hydrochlorothiazide  Manufacturing delays  Date of shortage:
8th September 2020

Expected return date:
Week commencing 1st November 2021		 Last updated:
20th October 2021
Losartan 50mg Tablet 

PA2315/059/002 		 Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
Unknown at present 		 Last updated:
13th April 2021
Losartan 100mg Tablet

PA2315/059/003 		 Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film-Coated Tablets

PA0749/026/001
 Losartan & Hydrochlorothiazide
  Quality issue Date of shortage: Late October 2021  

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets

PA0749/026/002
 Losartan & Hydrochlorothiazide
 Quality issue  Date of shortage: 
Late October 2021

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
Unknown at present 
 Last updated: 
24th September  2021 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Metaraminol 10mg/ml Solution for Injection or Infusion 

PA22893/001/001		 Metaraminol  Awaiting update Date of shortage: 
Early April 2021 

Expected return date:
Awaiting update		 Last updated: 
30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution

PA23081/008/001
 Metformin  Regulatory Issue Date of shortage: 
13th August 2021

Expected return date: 
Unknown at present		 Last updated: 
10th August 2021
Mydrilate 1.0% w/v Eye Drops

PA22709/003/002
 Cyclopentolate Manufacturing delay  Date of shortage:
Early September 2021

Expected return date: 
Mid-October 2021		 Last updated: 
27th September 2021 
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion 

PA0073/111/002
 Naloxone Manufacturing delay  Date of shortage: 
18th October 2021

Expected return date: 
3rd December 2021 		 Last updated: 
19th October 2021
Nanocis 0.24mg Kit for Radiopharmaceutical Preparation

PA0677/006/001
 Rhenium sulphide
 Awaiting information  Date of shortage: 
Week commencing 20th September 2021 

Expected return date: 
Week commencing 8th November 2021		 Last updated: 
1st October 2021
Odrik 2mg Hard Capsule

PA2010/005/003
 Trandolapril
 Manufacturing delays Date of shortage: 
5th October 2021

Expected return date: 
Late October 2021 		 Last updated: 
28th September 2021
Oramox 125mg/5ml Powder for Oral Suspension

PA0298/019/001
 Amoxicillin
 Unexpected increase in demand  Date of shortage:
22nd October 2021 

Expected return date: 
Unknown at present 		 Last updated: 
19th October 2021 
OxyContin 5mg Prolonged Release Tablets 

PA1688/005/001
  Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021		 Last updated:
12th October 2021
OxyNorm Dispersa 5mg Orodispersible Tablets

PA1688/006/007
 Oxycodone  Unexpected increase in demand  Date of shortage: 
5th October 2021 

Expected return date: 
4th November 2021		 Last updated: 
18th October 2021
OxyNorm Dispersa 10mg Orodispersible Tablets

PA1688/006/008
 Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date:
Unknown at present 		  Last updated: 
12th October 2021
OxyNorm Dispersa 20mg Orodispersible Tablets

PA1688/006/009
 Oxycodone Manufacturing delays  Date of shortage: 
26th October 2021 

Expected return date:
February 2022		 Last updated: 
20th October 2021 
Palexia 4mg/ml Oral Solution

PA2242/012/010 		 Tapentadol hydrochloride  Quality issue

(multiple countries affected) 		 Date of shortage:
15th February 2021

Expected return date:
Unknown at present 		 Last updated: 
22nd February 2021
Paralief 500mg Tablets 

24 pack only

PA0126/020/001
 Paracetamol API unavailability  Date of shortage: 
Week commencing 23rd August 2021

Expected return date: 
27th October 2021
 Last updated: 
28th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w

PA0278/017/002
 Hydrocortisone & Lidocaine Hydrochloride  Manufacturing delays  Date of shortage:
February 2021

Expected return date:
January 2022		 Last updated: 
8th April 2021
Qlaira Film Coated Tablets

PA1410/058/001
  Estradiol API unavailability  Date of shortage: 
Mid November 2021

Expected return date: 
Q2 2022		 Last updated: 
7th October 2021

HCP letter
Questran 4g Powder for Oral Suspension

PA2239/005/001 		 Colestyramine  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2019

Expected return date:
January 2022		 Last updated:
30th March 2021 
Rifater 50mg/300mg/120mg Tablets

PA0822/143/002
 Isoniazid & Pyrazinamide & Rifampicin Quality issue

(multiple countries impacted)		 Date of shortage: 
23rd July 2021

Expected return date: 
26th October 2021		 Last updated:
18th October 2021

AMRIC guidance V3
Rosuvastatin 5mg Film Coated Tablets

PA2315/068/001
 Rosuvastatin Quality issue  Date of shortage:
27th August 2021

Expected return date: 
Q2 2022		  Last updated: 
30th August 2021
Rosuvastatin 10mg Film Coated Tablets

PA2315/068/002
 Rosuvastatin  Quality issue Date of shortage: 
27th August 2021 

Expected return date: 
Q2 2022 		 Last updated: 
30th August 2021 
Rosuvastatin 20mg Film Coated Tablets

PA2315/068/003
 Rosuvastatin   Distribution issue Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 		 Last updated: 
21st October 2021 
Rosuvastatin 40mg Film Coated Tablets

PA2315/068/004
 Rosuvastatin   Distribution issue
 Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
 Last updated: 
21st October 2021 
Sevelamer Carbonate 800mg Film Coated Tablets

PA0577/205/001
 Sevelamer  Manufacturing delays Date of shortage: 
Late October

Expected return date: 
Unknown at present  		 Last updated: 
22nd October 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Mid-December 2021		 Last updated:
22nd October 2021
Stesolid Rectal Solution 5mg

PA2315/137/001
 Diazepam  Manufacturing delays Date of shortage: 
Late August 2021

Expected return date: 
November 2021		 Last updated: 
12th August 2021
Stesolid Rectal Solution 10mg

PA2315/137/002
  Diazepam Manufacturing delays  Date of shortage: 
Week commencing 19th July 2021. 

Expected return date: 
November 2021		 Last updated: 
21st July 2021
Targin 20mg/10mg Prolonged Release Tablets

PA1688/010/001		 Oxycodone & Naloxone  Shipping delays Date of shortage: 
27th September 2021 

Expected return date: 
28th October 2021
 Last updated: 
22nd October 2021
Telmisartan Rowa 40mg Tablets

PA0074/078/002
 Telmisartan  Unexpected increase in demand  Date of shortage: 
7th September 2021

Expected return date: 
Late November 2021		  Last updated: 
20th October 2021
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
 Alendronic acid API unavailability  Date of shortage: 
6th September 2021 

Expected return date: 
Late November 2021 		 Last updated: 
23rd August 2021 
Tracrium 10 mg/ml, Solution for injection or infusion

(25ml ampoule)

PA1691/029/002
 Atracurium  Unexpected increase in demand Date of shortage: 
24th September 2021 

Expected return date: 
20th November 2021 		 Last updated: 
24th September 2021
Trandate 200mg Film Coated Tablet

PA1638/006/003 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
End October 2021		 Last updated:
11th October 2021
TPN – various B. Braun products
 Various  Manufacturing delays  Date of shortage: 
4th October 2021

Expected return date: 
Unknown at present		 Last updated: 
5th October 2021

HCP letter
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment

PA22650/004/001
 Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride  Regulatory issue Date of shortage: 
Late September 2021

Expected return date: 
Late December 2021
 Last updated: 
15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets

PA1688/011/001
Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abstral 100mcg Sublingual Tablets

PA2288/004/002
  Fentanyl  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
3rd September 2021 

Expected return date: 
Week commencing 1st October 2021		 Last updated: 
22nd October 2021
Abstral 200mcg Sublingual Tablets

PA2288/004/003
 Fentanyl Manufacturing delays 

(multiple countries affected)		 Date of shortage:
15th August 2021

Return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 300mcg Sublingual Tablets

PA2288/004/004
 Fentanyl  Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
5th October 2021

Expected return date: 
Week commencing 25th October 2021
 Last updated: 
22nd October 2021
Abstral 400mcg Sublingual Tablets

PA2288/004/005
 Fentanyl  Manufacturing delays 

(multiple countries affected)
 Date of shortage: 
4th October 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Abstral 600mcg Sublingual Tablets

PA2288/004/006
 Fentanyl   Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
2nd September 2021 

Expected return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 700mcg Sublingual Tablets

PA2288/004/007
 Fentanyl Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
2nd September 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Adizem-XL 180mg Prolonged Release Capsules

PA1688/001/005
 Dilitazem  Manufacturing delays Date of shortage: 
1st October 2021

Expected return date: 
November 2021 		 Last updated: 
27th September 2021
Amitriptyline 25mg Film Coated Tablets

PA0126/041/001
 Amitriptyline
 API unavailability Date of shortage: 
2nd September 2021 

Expected return date: 
Late October 2021		 Last updated: 
7th September 2021 

HCP letter
Astilin 10mg Tablets

PA23163/001/001
 Amitriptyline  Awaiting update Date of shortage: 
27th August 2021

Expected return date: 
29th October 2021		 Last updated: 
5th October 2021

HCP letter
Ativan 4mg/ml Solution for Injection

PA0822/090/002 		 Lorazepam  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2020

Expected return date:
Unknown at present		 Last updated:
14th May 2021 
 
HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
2022		 Last updated:
3rd February 2021
Bendroflumethiazide 2.5mg Tablets

PA22749/021/001
 Bendroflumethiazide
  Regulatory issue Date of shortage:
3rd September 2021

Expected return date: 
Awaiting update		 Last updated: 
1st October 2021
Beromun 1mg Powder for Solution for Infusion

EU/1/99/097/001 		 Tasonermin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
December 2020

Expected return date:
November 2021		 Last updated:
1st June 2021
Calcium Acetate 500mg Tablets

PA0281/063/001
 Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
Late December 2021		 Last updated: 
30th September 2021
Canesten HC 1% w/w + 1% w/w Cream

PA1410/040/002
 Clotrimazole & Hydrocortisone  Manufacturing delays Date of shortage: 
30th September 2021 

Expected return date:
5th November 2021		 Last updated: 
22nd September 2021
Catapres Tablets 100mcg

PA2256/003/001
  Clonidine Manufacturing delays

(multiple countries affected)		 Date of shortage: 
25th July 2021

Expected return date: 
25th October 2021		 Last updated: 
21st June 2021 
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution

PA2299/005/001
 Chlorhexidine acetate & cetrimide
 Unexpected increase in demand Date of shortage: 
September 2021 

Expected return date: 
Mid November 2021 		 Last updated: 
20th October 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution

PA0281/124/001 		 Chlorpromazine hydrochloride  Manufacturing delays  Date of shortage:
End of February 2021

Expected return date:
End January 2022		 Last updated:
5th October 2021
 
HCP letter
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes 

PA0540/097/008
 Enoxaparin sodium  API unavailability   Date of shortage: 
22nd October 2021 

Expected return date: 
Unknown at present		 Last updated: 
13th October 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion

PA1457/001/001
 Amoxicillin & Clavulanic acid
 Manufacturing delays Date of shortage: 
13th October 2021 

Expected return date: 
Awaiting update		 Last updated: 
18th October 2021 
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion

PA1457/001/002		 Amoxicillin & clavalunic acid Unexpected increase in demand Date of shortage:
5th February 2020

Expected return date:
Awaiting update
 Last updated:
19th October 2021
CoAprovel 300mg/12.5mg Tablets

EU/1/98/086/004
 Irbesartan & Hydrochlorothiazide  Shipping delay  Date of shortage: 
5th November 2021

Expected return date: 
Late November 2021  		 Last updated: 
22nd October 2021 
Cyklokapron 100 mg/mL Solution for Injection/Infusion

PA0822/117/001
 Tranexamic acid Manufacturing delays Date of shortage: 
Week commencing 18th October 2021

Expected return date: 
Week commencing 15th November 2021 		 Last updated: 
5th October 2021 
Deslor 5mg Film Coated Tablets

PA0711/202/001
 Desloratidine Awaiting information   Date of shortage: 
19th September  2021  

Expected return date: 
Late December 2021		 Last updated: 
October 2021 
Desmopressin 100mcg/ml Nasal Drop Solution

PA1009/001/001 		 Desmopressin  Manufacturing delays due to quality issue

(multiple countries affected) 		 Date of shortage:
Mid December 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Dioralyte Blackcurrant Powder for Oral Solution (20 pack)

PA0540/098/001
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate  Unexpected increase in demand  Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021		 Last updated: 
30th September 2021
Dioralyte Citrus Powder for Oral Solution
(20 pack)

PA0540/098/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution
(6 pack)

PA0540/194/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Doxatan 4mg Tablets

PA0126/202/003 		 Doxazosin  Manufacturing delay   Date of shortage: 
4th October 2021

Expected return date:
Week commencing 1st November 2021		 Last updated: 
20th October 2021
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005		 Phenytoin Manufacturing delays

(multiple countries affected)		 Date of shortage:
Early November 2019

Expected return date:
Unknown at present		 Last updated:
4th June 2020
 
HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion

PA1852/002/001 		 Esomeprazole  Unavailability of API  Date of shortage:
Early October 2020

Expected return date:
Late November 2021		 Last updated:
12th October 2021
Ezetimibe Rowa 10mg Tablets

PA0074/074/001
 Ezetimibe Awaiting information  Date of shortage: 
19th October 2021 

Expected return date: 
Late November 2021 		 Last updated: 
21st October 2021
Ezetimibe Teva 10mg tablets

PA1986/012/001
 Ezetimibe  Quality Issue  Date of shortage: 
18th October 2021 

Expected return date: 
13th December 2021		 Last updated: 
4th October 2021
Ezetimibe 10mg tablets

PA0577/198/001
 Ezetimibe
 Manufacturing delays  Date of shortage: 
Late August 2021 

Expected return date: 
Early November 2021		 Last updated: 
4th October 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets

PA0711/262/001
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 22nd July 2021

Expected return date: 
October 2021		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date: 
End November 2021
 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets

PA1986/067/003
 Ezetimibe & simvastatin
 API unavailability

(multiple countries impacted) 		 Date of shortage: 
30th August 2021 

Expected return date: 
Awaiting update		 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets

PA0126/281/002
Ezetimibe & simvastatin
 Manufacturing delays   Date of shortage: 
Week commencing 20th September 2021

Expected return date: 
Unknown at present		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets

PA0126/281/004
 Ezetimibe & simvastatin
 Manufacturing delays Date of shortage: 
Week commencing 20th September 2021

Expected return date:  
Unknown at present		 Last updated: 
20th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection

PA0822/198/002
 Folinic Acid  Unexpected increase in demand Date of shortage: 
Week commencing 27th September 2021

Expected return date: 
Awaiting update		 Last updated:
18th October 2021
Fomicyt 40mg/ml Powder for Solution for Infusion

PA1972/001/001
 Fosfomycin sodium Regulatory issue  Date of Shortage: 
October 2021 

Expected return date: 
Unknown at present		 Last updated: 
12th October 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension

PA1142/014/001
 Gentamicin & Hydrocortisone Unavailability of API 

(multiple countries affected)		 Date of shortage: 
23rd August 2021

Expected return date:
Late November 2021		 Last updated: 
9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Imodium Plus 2mg/125mg Tablets

PA0330/050/001
 Loperamide & simeticone  Manufacturing delay  Date of shortage: 
11th October 2021 

Expected return date:
Week commencing 22nd November 2021		 Last updated: 
20th October 2021
Innohep 10,000 IU/ml Solution for Injection

PA0046/060/002
 Tinzaparin sodium
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
20th September 2021

Expected return date: 
Mid-November 2021
 Last updated: 
23rd September 2021
Instanyl 50mcg Nasal Spray 

EU/1/09/531/010-013
 Fentanyl  Quality issue 
(multiple countries affected)		 Date of shortage: 
1st August 2021 

Expected return date: 
February 2022
 Last updated: 
20th August 2021
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated: 
20th August 2021
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated:
20th August 2021
Invokana 300mg Film Coated Tablets

EU/1/13/884/005-008		 Canagliflozin
 Unexpected increase in demand  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021 		 Last updated: 
12th October 2021
Letrozole 2.5mg Film Coated Tablets

PA2315/109/001
 Letrozole  Awaiting information   Date of shortage: 
Week commencing 25th October 2021

Expected return date: 
End November 2021		 Last updated: 
18th October 2021 
Letrozole 2.5mg Film Coated Tablets

PA0126/198/001
 Letrozole  Manufacturing delays  Date of shortage: 
22nd October 2021 

Expected return date: 
22nd December 2021		 Last updated: 
18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets

PA0749/085/001
 Letrozole  API unavailability 

(multiple countries affected) 		 Date of shortage: 
Week commencing 9th August 2021

Expected return date: 
January 2021		 Last updated: 
5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet

PA0711/051/002 		 Lisinopril & Hydrochlorothiazide  Manufacturing delays  Date of shortage:
8th September 2020

Expected return date:
Week commencing 1st November 2021		 Last updated:
20th October 2021
Losartan 50mg Tablet 

PA2315/059/002 		 Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
Unknown at present 		 Last updated:
13th April 2021
Losartan 100mg Tablet

PA2315/059/003 		 Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film-Coated Tablets

PA0749/026/001
 Losartan & Hydrochlorothiazide
  Quality issue Date of shortage: Late October 2021  

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets

PA0749/026/002
 Losartan & Hydrochlorothiazide
 Quality issue  Date of shortage: 
Late October 2021

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
Unknown at present 
 Last updated: 
24th September  2021 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Metaraminol 10mg/ml Solution for Injection or Infusion 

PA22893/001/001		 Metaraminol  Awaiting update Date of shortage: 
Early April 2021 

Expected return date:
Awaiting update		 Last updated: 
30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution

PA23081/008/001
 Metformin  Regulatory Issue Date of shortage: 
13th August 2021

Expected return date: 
Unknown at present		 Last updated: 
10th August 2021
Mydrilate 1.0% w/v Eye Drops

PA22709/003/002
 Cyclopentolate Manufacturing delay  Date of shortage:
Early September 2021

Expected return date: 
Mid-October 2021		 Last updated: 
27th September 2021 
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion 

PA0073/111/002
 Naloxone Manufacturing delay  Date of shortage: 
18th October 2021

Expected return date: 
3rd December 2021 		 Last updated: 
19th October 2021
Nanocis 0.24mg Kit for Radiopharmaceutical Preparation

PA0677/006/001
 Rhenium sulphide
 Awaiting information  Date of shortage: 
Week commencing 20th September 2021 

Expected return date: 
Week commencing 8th November 2021		 Last updated: 
1st October 2021
Odrik 2mg Hard Capsule

PA2010/005/003
 Trandolapril
 Manufacturing delays Date of shortage: 
5th October 2021

Expected return date: 
Late October 2021 		 Last updated: 
28th September 2021
Oramox 125mg/5ml Powder for Oral Suspension

PA0298/019/001
 Amoxicillin
 Unexpected increase in demand  Date of shortage:
22nd October 2021 

Expected return date: 
Unknown at present 		 Last updated: 
19th October 2021 
OxyContin 5mg Prolonged Release Tablets 

PA1688/005/001
  Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021		 Last updated:
12th October 2021
OxyNorm Dispersa 5mg Orodispersible Tablets

PA1688/006/007
 Oxycodone  Unexpected increase in demand  Date of shortage: 
5th October 2021 

Expected return date: 
4th November 2021		 Last updated: 
18th October 2021
OxyNorm Dispersa 10mg Orodispersible Tablets

PA1688/006/008
 Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date:
Unknown at present 		  Last updated: 
12th October 2021
OxyNorm Dispersa 20mg Orodispersible Tablets

PA1688/006/009
 Oxycodone Manufacturing delays  Date of shortage: 
26th October 2021 

Expected return date:
February 2022		 Last updated: 
20th October 2021 
Palexia 4mg/ml Oral Solution

PA2242/012/010 		 Tapentadol hydrochloride  Quality issue

(multiple countries affected) 		 Date of shortage:
15th February 2021

Expected return date:
Unknown at present 		 Last updated: 
22nd February 2021
Paralief 500mg Tablets 

24 pack only

PA0126/020/001
 Paracetamol API unavailability  Date of shortage: 
Week commencing 23rd August 2021

Expected return date: 
27th October 2021
 Last updated: 
28th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w

PA0278/017/002
 Hydrocortisone & Lidocaine Hydrochloride  Manufacturing delays  Date of shortage:
February 2021

Expected return date:
January 2022		 Last updated: 
8th April 2021
Qlaira Film Coated Tablets

PA1410/058/001
  Estradiol API unavailability  Date of shortage: 
Mid November 2021

Expected return date: 
Q2 2022		 Last updated: 
7th October 2021

HCP letter
Questran 4g Powder for Oral Suspension

PA2239/005/001 		 Colestyramine  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2019

Expected return date:
January 2022		 Last updated:
30th March 2021 
Rifater 50mg/300mg/120mg Tablets

PA0822/143/002
 Isoniazid & Pyrazinamide & Rifampicin Quality issue

(multiple countries impacted)		 Date of shortage: 
23rd July 2021

Expected return date: 
26th October 2021		 Last updated:
18th October 2021

AMRIC guidance V3
Rosuvastatin 5mg Film Coated Tablets

PA2315/068/001
 Rosuvastatin Quality issue  Date of shortage:
27th August 2021

Expected return date: 
Q2 2022		  Last updated: 
30th August 2021
Rosuvastatin 10mg Film Coated Tablets

PA2315/068/002
 Rosuvastatin  Quality issue Date of shortage: 
27th August 2021 

Expected return date: 
Q2 2022 		 Last updated: 
30th August 2021 
Rosuvastatin 20mg Film Coated Tablets

PA2315/068/003
 Rosuvastatin   Distribution issue Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 		 Last updated: 
21st October 2021 
Rosuvastatin 40mg Film Coated Tablets

PA2315/068/004
 Rosuvastatin   Distribution issue
 Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
 Last updated: 
21st October 2021 
Sevelamer Carbonate 800mg Film Coated Tablets

PA0577/205/001
 Sevelamer  Manufacturing delays Date of shortage: 
Late October

Expected return date: 
Unknown at present  		 Last updated: 
22nd October 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Mid-December 2021		 Last updated:
22nd October 2021
Stesolid Rectal Solution 5mg

PA2315/137/001
 Diazepam  Manufacturing delays Date of shortage: 
Late August 2021

Expected return date: 
November 2021		 Last updated: 
12th August 2021
Stesolid Rectal Solution 10mg

PA2315/137/002
  Diazepam Manufacturing delays  Date of shortage: 
Week commencing 19th July 2021. 

Expected return date: 
November 2021		 Last updated: 
21st July 2021
Targin 20mg/10mg Prolonged Release Tablets

PA1688/010/001		 Oxycodone & Naloxone  Shipping delays Date of shortage: 
27th September 2021 

Expected return date: 
28th October 2021
 Last updated: 
22nd October 2021
Telmisartan Rowa 40mg Tablets

PA0074/078/002
 Telmisartan  Unexpected increase in demand  Date of shortage: 
7th September 2021

Expected return date: 
Late November 2021		  Last updated: 
20th October 2021
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
 Alendronic acid API unavailability  Date of shortage: 
6th September 2021 

Expected return date: 
Late November 2021 		 Last updated: 
23rd August 2021 
Tracrium 10 mg/ml, Solution for injection or infusion

(25ml ampoule)

PA1691/029/002
 Atracurium  Unexpected increase in demand Date of shortage: 
24th September 2021 

Expected return date: 
20th November 2021 		 Last updated: 
24th September 2021
Trandate 200mg Film Coated Tablet

PA1638/006/003 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
End October 2021		 Last updated:
11th October 2021
TPN – various B. Braun products
 Various  Manufacturing delays  Date of shortage: 
4th October 2021

Expected return date: 
Unknown at present		 Last updated: 
5th October 2021

HCP letter
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment

PA22650/004/001
 Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride  Regulatory issue Date of shortage: 
Late September 2021

Expected return date: 
Late December 2021
 Last updated: 
15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets

PA1688/011/001

Date of shortage: 
20th October 2021 

Expected return date: 
Unknown at present

Anapen 300 micrograms in 0.3ml solution for injection in a pre-filled syringe

Cholera vaccine
Cholera vaccine

Sterculia
Frangula

Manufacturing delay

Duloxetine 
Duloxetine

Amdipharm Limited
Amdipharm Limited

PA1186/011/001
PA1186/011/001
Chefaro Ireland DAC
Chefaro Ireland DAC

Clonmel Healthcare Ltd

Bayer Limited

Baxter Holding B.V.

Santen OY


Contact us:

Medicinal Product Shortages Unit
Health Products Regulatory Authority 
Kevin O’Malley House
Earlsfort Terrace,
Dublin 2
Tel: +353 1 676 4971
Fax: +353 1 676 7836
shortages@hpra.ie