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Medicinal Product Shortages

The HPRA is responsible for co-ordinating the management of shortages of human medicines on the Irish market. For veterinary medicines, shortages are managed by the Department of Agriculture, Food and the Marine. 

The HPRA works with a variety of stakeholders including manufacturers, wholesale distributors, marketing authorisation holders, healthcare professionals, the Health Service Executive, patients and representative groups to respond to potential shortages and reduce the impact of shortages on patients.

The definition of a shortage is when the supply of a medicinal product is inadequate to meet the needs of the patient. 

The HPRA, in collaboration with stakeholders, has published a framework for a multi-stakeholder approach to handling shortages of human medicinal products. The aim of the framework is to help prevent shortages from occurring and to reduce the impact of shortages on patients by co-ordinating the management of potential or actual shortages as they arise. You can see the shortages case study on Adrenaline auto-injectors (AAIs) as an example of how the framework operates in practice. 


Information on reporting shortages for:

Marketing Authorisation Holders

Please complete the  Notification of medicinal product shortage from marketing authorisation holder form and return to  shortages@hpra.ie and to the HSE Corporate Pharmaceutical Unit.

Wholesale Distributors and Manufacturers

Please complete the  Report of Medicinal Products Shortages from Wholesale Distributors and Manufacturers form and return this form to  shortages@hpra.ie.

Patients and Healthcare Professionals

Please complete the  Report of a Medicinal Product Shortage from Patients and Healthcare Professionals form and return to  shortages@hpra.ie. When completing this form, please include as much information as possible.

Veterinary Medicines

Please contact the Department of Agriculture, Food and the Marine.

Current and resolved shortages

The HPRA publishes a list of shortages currently affecting the Irish market that have been notified to us and that may have a medium or high impact on patients. This list can be found below. More information on the impact level can be found in the framework for a multi-stakeholder approach to handling shortages of human medicinal products.

The HPRA maintains a consolidated list of resolved shortages for a period of six months. Details of shortages that have been resolved in the last six months can be found here.
 

Hormone replacement therapy (HRT) shortages

HRT shortages have impacted multiple countries over the past year and are not restricted to Ireland. While there are shortages of some specific brands, alternatives are available to meet patient need. The suppliers have stated that the causes of the shortages relate to both active substance availability and manufacturing delays. It is not related to Brexit. The HPRA continues to be in frequent contact with the suppliers to maintain efforts to expedite re-supply as soon as possible. The HPRA website will be will be kept up to date as additional information becomes available.

 

If a patient has any concerns about their medicine, the HPRA advises that they should discuss their treatment a doctor or pharmacist.


Please use search function below to find relevant product or active ingredient

 
Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Adalat LA 20mg Prolonged Release Tablet

PA1410/025/005		 Nifedipine  Manufacturing delays

(multiple countries affected)		 Date of shortage:
November 2017
 
Expected return date:
Not before 2021		 Last updated:
29th November 2019
 
Adalat LA 30mg Prolonged Release Tablet

PA1410/025/006		 Nifedipine  Manufacturing delays

(multiple countries affected)		 Date of shortage:
24th June 2018

Expected return date:
Not before 2021
 Last updated:
29th November 2019 
 
Adalat LA 60mg Prolonged Release Tablet

PA1410/025/007 		 Nifedipine Manufacturing delays

(multiple countries affected)		 Date of shortage:
September 2018

Expected return date:
Not before 2021		 Last updated:
29th November 2019
 
Alendronate/Colecalciferol Teva 70mg/5600IU Tablet

PA0749/196/002 		 Alendronate & Colecalciferol  Manufacturing delays  Date of shortage:
January 2019

Expected return date:
End of August 2020 		 Last updated:
17th July 2020 
Amisulpride 50mg Tablet

PA0577/182/001 		 Amisulpride  Manufacturing delays  Date of shortage:
July 2019

Expected return date:
August 2020		 Last updated:
26th June 2020 
Areloger 15mg Film Coated Tablet

PA0577/057/002 		 Meloxicam  Manufacturing delays  Date of shortage:
Early August 2019

Expected return date:
August 2020		 Last updated:
18th February 2020 
Aripiprazole 30mg Tablet

PA1986/019/004 		 Aripiprazole  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid July 2020

Expected return date:
Unknown at present 		 Last updated:
17th July 2020 
Arthrotec 50 Modified Release Tablet

PA0822/112/001 		 Diclofenac & Misoprostol  Manufactuirng delays  Date of shortage:
20th April 2020

Expected return date:
Early August 2020 		 Last updated:
26th June 2020 
             
HCP Letter
Atecor 50mg Tablet

PA0711/003/002 		 Atenolol  Manufacturing delays  Date of shortage:
22nd July 2020

Expected return date:
Mid August 2020 		 Last updated:
30th July 2020 
Atecor CT 50mg/12.5mg Tablet

PA0711/020/001		 Chlortalidone & Atenolol  Manufacturing delays  Date of shortage:
Early July 2020

Expected return date:
10th October 2020 		 Last updated:
23rd July 2020 
Ativan 4mg/ml Solution for Injection

PA0822/090/002 		 Lorazepam  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2020

Expected return date:
Unknown at present 		 Last updated:
31st July 2020 
Atorvastatin 80mg Tablet

PA0126/271/004		 Atorvastatin Manufacturing delays Date of shortage:
11th May 2020

Expected return date:
5th August 2020		 Last updated:
13th May 2020 
Axsain 0.075% w/w Cream

PA0827/004/001 		 Capsaicin  Manufacturing delays 

(multiple countries affected)		 Date of shortage:
Mid June 2019

Expected return date:
End of August 2020		 Last updated:
5th August 2020 
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
Unknown at present 		 Last updated:
7th November 2019 
Blopress 16mg Tablet

PA2229/001/004
  Candesartan Manufacturing delays

(multiple countries affected)		 Date of shortage:
11th May 2020

Expected return date:
Awaiting update		 Last updated:
31st July 2020 
Candist 8mg Tablet

PA0126/206/002 		 Candesartan  Unexpected increase in demand

 		 Date of shortage:
End of April 2020

Expected return date:
Mid August 2020		 Last updated:
24th April 2020 
Candist Plus 16mg/12.5mg Tablet

PA0126/207/002 		 Candesartan & Hydrochlorothiazide  Unexpected increase in demand  Date of shortage:
13th July 2020

Expected return date:
9th September 2020 		 Last updated:
13th July 2020 
Canesten Duopack - 100mg Pessary & 1% w/w Cream

PA1410/039/005 		 Clotrimazole  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
February 2018

Expected return date:
August 2020 		 Last updated:
7th May 2020
             
HCP Letter
Canesten 200mg Pessary

PA1410/039/008 		 Clotrimazole  Manufacturing delay

(multiple countries affected) 		 Date of shortage:
February 2018

Expected return date:
August 2020		 Last updated:
7th May 2020
             
HCP Letter
Canesten 500mg Pessary

PA1410/039/009 		 Clotrimazole  Manufacturing delay

(multiple countries affected) 		 Date of shortage:
January 2018

Expected return date:
August 2020		 Last updated:
7th May 2020
                         
HCP Letter
Catasart 8mg Tablet

PA0711/134/002 		 Candesartan  Manufcaturing delays  Date of shortage:
20th May 2020

Expected return date:
End of August 2020		 Last updated:
16th June 2020 
Celecoxib 100mg Capsule

PA0711/241/001 		 Celecoxib  Manufacturing delays  Date of shortage:
Mid May 2020

Expected return date:
13th August 2020 		 Last updated:
16th June 2020 
Celecoxib 200mg Capsule

PA0711/241/002 		 Celecoxib  Manufacturing delays  Date of shortage:
Mid June 2020

Expected return date:
Awaiting update		 Last updated:
14th July 2020 
Centyl K 2.5mg + 573mg Tablet

PA22650/002/002 		 Bendroflumethiazide & Potassium hydrochloride  Unepxected Increase in demand  Date of shortage:
6th August 2020

Expected return date:
End of October 2020 		 Last updated:
5th August 2020 
Cimeldine 400mg Film Coated Tablet

PA0126/077/002 		 Cimetidine  API delay  Date of shortage:
9th December 2019

Expected return date:
11th August 2020		 Last updated:
9th July 2020 
Ciprofloxacin Teva 250mg Film Coated Tablet


PA0749/031/002 		 Ciprofloxacin  Manufacturing delays  Date of shortage:
Early September 2019

Expected return date:
End of August 2020		 Last updated:
17th July 2020
Co-Amoxiclav 1000mg/200mg Powder for solution for injection/infusion

PA1339/005/002		 Amoxicillin & clavalunic acid Unexpected increased demand Date of shortage:
5th February 2020

Expected return date:
Unknown at present
 Last updated:
4th June 2020 
Creon 25000 Gastro-resistant Capsule

PA2010/008/002 		 Pancreatin  Delay in delivery  Date of shortage:
31st July 2020

Expected return date:
Awaiting update 		 Last updated:
5th August 2020 
Deslor 0.5mg/ml Oral Solution

PA0711/202/002 		 Desloratidine  Manufacturing delays  Date of shortage:
Mid June 2020

Expected return date:
Awaiting update 		 Last updated:
27th July 2020 
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
Unknown at present 		 Last updated:
23rd July 2020 
Diabrezide 80mg Tablet

PA0925/001/001 		 Gliclazide  Manufacturing delays  Date of shortage:
End of May 2020

Expected return date:
Awaiting update		 Last updated:
4th August 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present 		 Last updated:
17th July 2020 
Efexor XL 150mg Prolonged Release Capsule

PA0822/072/003 		 Venlafaxine  Unavailability of API

(multiple countries affected) 		 Date of shortage:
24th July 2020

Expected return date:
17th August 2020 		 Last updated:
20th July 2020 
Emazole 40mg Gastro-Resistant Tablet

PA0711/158/002 		 Esomeprazole  Manufacturing delays  Date of shortage:
End of May 2020

Expected return date:
Awaiting update		 Last updated:
22nd July 2020 
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
30th September 2019

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
30th September 2019

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
30th September 2019

Alternatives are available 
Enap 10mg Tablet

PA0711/028/002 		 Enalapril  Manufacturing delay  Date of shortage:
End of April 2020

Expected return date:
Mid August 2020 		 Last updated:
4th June 2020 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005		 Phenytoin Manufacturing delays

(multiple countries affected)		 Date of shortage:
Early November 2019

Expected return date:
Unknown at present		 Last updated:
4th June 2020
 
HCP Letter
Erythrocin 250mg Tablet

PA1142/008/002 		 Erythrocin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2019

Expected return date:
August 2020		 Last updated:
27th May 2020 
Erythrocin 500mg Tablet

PA1142/008/003 		 Erythrocin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
End of February 2020

Expected return date:
August 2020
 Last updated:
27th May 2020 
Erythroped PI SF 125mg/5ml Granules for Oral Suspension

PA1142/006/002 		 Erythromycin  Manufacturing delays 

(multiple countries affected)		 Date of shortage:
End of June 2019

Expected return date:
August 2020 		 Last updated:
27th May 2020 
Erwinase 10,000 Units Powder for Solution for Injection

PA1020/002/001 		 Crisantaspace  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
30th July 2020

Expected return date:
24th August 2020 		 Last updated:
4th August 2020 
Estradot 37.5mcg/day Transdermal Patch

PA0896/010/001 		 Estradiol  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
End of June 2020

Expected return date:
October 2020 		 Last updated:
27th July 2020
 
 HCP Letter 
Estradot 100mcg/day Transdermal Patch

PA0896/010/004 		 Estradiol  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early June 2020

Expected return date:
October 2020 		 Last updated:
27th July 2020
             
HCP Letter
Evorel 50mcg Transdermal Patch

PA22668/008/001 		 Estradiol  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
October 2019

Expected return date:
Awaiting update		 Last updated:
5th August 2020
             

 
Evorel Conti 50mcg/170mcg Transdermal Patch

PA22668/009/001 		 Estradiol & Norethisterone Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early January 2020

Expected return date:
Awaiting update 		 Last updated:
5th August 2020
             

 
             
Ezetimibe/Simvastatin Clonmel 10mg/10mg 

PA0126/281/001		 Ezetimibe & Simvastatin  Manufacturing delay  Date of shortage:
6th January 2020

Expected return date:
Awaiting update
 Last updated:
22nd July 2020
Folinic Acid 10mg/ml Solution for Injection

(100mg/10ml presentation only)

PA0822/198/003 		 Folinic acid  Manufacturing delays  Date of shortage:
5th July 2019

Expected return date:
Awaiting update		 Last updated:
22nd July 2020
Flixotide 0.5mg/2ml Nebules

PA1077/044/016 		 Fluticasone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
13th May 2020

Expected return date:
2021 		 Last updated:
28th May 2020 
Flucol 150mg Capsule

PA0711/057/003 		 Fluconazole  Manufacturing delays  Date of shortage:
10th June 2020

Expected return date:
Mid August 2020 		 Last updated:
7th July 2020 
Fluzac 20mg Capsule

PA0711/110/001 		 Fluoxetine  Unexpected increase in demand  Date of shortage:
17th April 2020

Expected return date:
Awaiting update		 Last updated:
27th July 2020 
Foznol 750mg Chewable Tablet

PA1575/002/003 		 Ianthanum carbonate hydrate  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
12th June 2020

Expected return date:
Awaiting update		 Last updated:
22nd July 2020 
Foznol 1000mg Chewable Tablet

PA1575/002/004 		 Ianthanum carbonate hydrate  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
12th June 2020

Expected return date:
Awaiting update		 Last updated:
17th July 2020 
Galfer 305mg Capsule

PA0126/314/001 		 Ferrous fumarate  Manufacturing delays  Date of shortage:
5th August 2020

Expected return date:
17th August 2020 		 Last updated:
31st July 2020 
Gaviscon Advance Oral Suspension

PA0979/015/001 		 Sodium alginate & Potassium hydrogen carbonate  Manufacturing delays  Date of shortage:
June 2020

Expected return date:
Awaiting update 		 Last updated:
31st July 2020 
Genotropin Miniquick 1.6mg Powder and Solvent for Solution for Injection

PA0822/128/010 		 Somatropin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid March 2020

Expected return date:
End of August 2020 		 Last updated:
2nd July 2020 
Genotropin Miniquick 2mg Powder and Solvent for Solution for Injection

PA0822/128/012 
 Somatropin
 Manufacturing delays

(multiple countries affected)  		 Date of shortage:
6th February 2020

Expected return date:
Week commencing 5th August 2020 
 Last updated:
5th August 2020
Gentamicin 40 mg/ml Injection, vials

PA0822/203/001
 Gentamicin
 Manufacturing delays

(multiple countries impacted)		 Date of shortage:
9th December 2019

Expected return date:
August 2020
 Last updated:
10th February 2020
Gerozac 20mg Capsule

PA0577/200/001 		 Fluoxetine  Manufacturing delays  Date of shortage:
Early December 2019

Expected return date:
Unknown at present 		 Last updated:
26th June 2020 
Gerozac 60mg Capsule

PA0577/071/001 		 Fluoxetine  Manufacturing delays  Date of shortage:
Early December 2020

Expected return date:
Unknown at present		 Last updated:
26th June 2020 
Gertac 150mg Film Coated Tablet

PA0577/023/001 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers 

AHDMP Guidance for Prescribers
Gertac 300mg Film Coated Tablet

PA0577/023/002 		 Ranitidine  Active substance impurities

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers 

AHDMP Guidance for Prescribers
HBVAXPRO 40mcg Suspension for Injection

EU/1/01/183/015 		 Hepatitis B  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
12th November 2019

Expected return date:
End of 2020 		 Last updated:
13th November 2019 
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
November 2020 		 Last updated:
3rd July 2020 
Hypnovel 10mg/5ml Solution for Injection

PA2239/007/002		 Midazolam  Unexpected increase in demand  Date of shortage:
2nd April 2020

Expected return date:
Mid September 2020		 Last updated:
28th July 2020 
Hypovase 1mg Tablet

PA0822/195/002 		 Prazosin hydrochloride  Manufacturing delay 

(multiple countries affected)		 Date of shortage:
Mid June 2019

Expected return date:
Unknown at present		 Last updated:
2nd June 2020
Hytrin 2mg Tablet

PA1142/005/002 		 Terazosin  Manufacturing delay 

(multiple countries affected)		 Date of shortage:
Early June 2020

Expected return date:
End of August 2020 		 Last updated:
27th July 2020 
Imdur 60mg Prolonged Release Tablet

PA2129/001/001 		 Isosorbide mononitrate  Manufacturing delays

(multiple countries affected)		 Date of shortage:
Mid May 2020

Expected return date:
Early August 2020 		 Last updated:
22nd July 2020 
Irprestan 150mg Film Coated Tablet

PA1380/021/002 		 Irprestan  Active substance impurity

(multiple countries affected) 		 Date of shortage:
February 2019

Expected return date:
October 2020		 Last updated:
3rd July 2019 
Isoptin 240mg Prolonged Release Tablet

PA2010/003/005 		 Verapamil  Manufacturing delay
 		 Date of shortage:
8th August 2020

Expected return date:
Mid September 2020 		 Last updated:
4th August 2020 
Lercanidipine Mylan 10mg Tablet

PA0577/155/001		 Lercanidipine  Unexpected increase in demand  Date of shortage:
Early November 2019

Expected return date:
October 2020 		 Last updated:
21st January 2020 
Lercanidipine Mylan 20mg Tablet

PA0577/155/002 		 Lercanidipine  Unexpected increase in demand  Date of shortage:
Early November 2019

Expected return date:
October 2020 		 Last updated:
21st January 2020
Levofloxacin 250mg Tablet

PA1347/048/001 		 Levofloxacin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
20th April 2020

Expected return date:
4th August 2020 		 Last updated:
1st July 2020 
Lipantil 145mg Film Coated Tablet

PA2010/015/003 		 Fenofibrate  Manufacturing delays  Date of shortage:
24th June 2020

Expected return date:
August 2020		 Last updated:
30th June 2020 
Lispril Hydrochlorothiazide 10mg/12.5mg Tablet

PA0711/051/001 		 Lisinopril & Hydrochlorothiazide  Manufacturing delays  Date of shortage:
22nd July 2020

Expected return date:
Unknown at present 		 Last updated:
29th July 2020 
Losamel 20mg Gastro-resistant tablets

PA0126/115/001		 Omeprazole Manufacturing delays Date of shortage: 
1st April 2020

Expected return date:
Unknown at present		 Last updated:
24th April 2020 
Losartan 50mg Tablet 

PA2315/059/002 		 Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
April 2021 		 Last updated:
22nd April 2020
Losartan 100mg Tablet

PA0749/090/004 		 Losartan  Unavailability of API

(multiple countries affected) 		 Date of shortage:
Early January 2020

Expected return date:
Awaiting update		 Last updated:
2nd July 2020 
Losartan 100mg Tablet

PA2315/059/003 		 Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
April 2021		 Last updated:
22nd April 2020 
Losartan Hydrochlorothiazide 50mg/12.5mg Tablet

PA0749/026/001 		 Losartan & Hydrochlorothiazide  Unavailability of API

(multiple countries affected) 		 Date of shortage:
24th November 2019

Expected return date:
December 2020		 Last updated:
17th July 2020 
Lotanos 100mg Film coated Tablet

PA0711/123/005 		 Losartan  Unexpected increase in demand  Date of shortage:
Mid February 2020

Expected return date:
22nd September 2020 		 Last updated:
28th July 2020 
Lyrica 75mg Capsule

EU/1/04/279/012 		 Pregabalin  Manufacturing delays  Date of shortage:
End of June 2020

Expected return date:
Week commencing 3rd August 2020 		 Last updated:
17th July 2020 
Maxibar 98.45% Powder for Oral Solution

PA1826/002/001 		 Barium sulphate  Manufacturing delays  Date of shortage:
End of July 2020

Expected return date:
Unknown at present 		 Last updated:
31st July 2020 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Q1 2021		 Last updated:
29th April 2020
 
Melcam 7.5mg Tablet

PA0711/060/001 		 Meloxicam  Manufacturing delays  Date of shortage:
November 2019

Expected return date:
2nd August 2020		 Last updated:
16th June 2020 
Melfen 200mg Film Coated Tablet

PA0126/012/001 		 Ibuprofen  Unexpected increased demand  Date of shortage:
6th July 2020

Expected return date:
Awaiting update 		 Last updated:
4th August 2020 
Miramel 0.18mg Tablet

PA0126/173/002 		 Pramipexole  Manufacturing delays  Date of shortage:
Early May 2020

Expected return date:
Awaiting update 		 Last updated:
31st July 2020 
Montelair 4mg Chewable Tablet

PA0126/215/001 		 Montelukast  Manufacturing delays  Date of shortage:
13th July 2020

Expected return date:
Mid September 2020 		 Last updated:
13th July 2020 
Montelair 5mg Chewable Tablet

PA0126/215/002 		 Montelukast  Manufacturing delays  Date of shortage:
13th July 2020

Expected return date:
Mid September 2020 		 Last updated:
13th July 2020 
Morphine Sulphate Injection BP 30mg/ml Solution for Injection

PA0361/004/005 		 Morphine Sulphate  Manufacturing delays  Date of shortage:
October 2018

Expected return date:
During 2020		 Last updated:
16th October 2019 
Muse 250mcg Urethral Stick

PA2010/028/002		 Alprostadil  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid March 2019
 
Expected return date:
Unknown at present		 Last updated:
25th May 2020
Neurontin 300mg Capsule

PA0822/015/002 		 Gabapentin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
End of June 2020

Expected return date:
Awaiting update 		 Last updated:
4th August 2020

HCP Letter 
Neurontin 800mg Capsule

PA0822/015/005 		 Gabapentin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
End of June 2020

Expected return date:
Awaiting update		 Last updated:
4th August 2020

HCP Letter 
Nexium Control 20mg Tablet

EU/1/13/860/001-002 		 Esomeprazole  Increased demand

(multiple countries affected) 		 Date of shortage:
Mid July 2020

Expected return date:
Mid August 2020 		 Last updated:
8th July 2020 
Nimbex 2mg/ml Solution for Infusion/Injection

PA1691/030/001		 Cistatracurium  Unexpected increase in demand

(multiple countries affected) 		 Date of shortage:
April 2020

Expected return date:
August 2020 		 Last updated:
13th May 2020 
Oprymea 0.088mg Tablet

EU/1/08/469/001-005 		 Pramipexole  Manufacturing delay  Date of shortage:
End of May 2020

Expected return date:
End of September 2020 		 Last updated:
3rd June 2020 
Perdamel 0.5mg Film Coated Tablet

PA0126/169/002 		 Risperidone  Manufacturing delays  Date of shortage:
20th January 2020

Expected return date:
17th August 2020 		 Last updated:
20th July 2020 
Perdamel 1mg Film Coated Tablet

PA0126/169/003 		 Risperidone  Manufacturing delays  Date of shortage:
Early August 2020

Expected return date:
11th September 2020 		 Last updated:
4th August 2020 
Piperacillin with Tazobactam 2.25g Powder for Solution for Injection

PA1339/001/001 		 Piperacillin sodium & Tazobactam sodium Manufacturing delays

(multiple countries affected)		 Date of shortage:
January 2018

Expected return date:
Unknown at present		 Last updated:
12th July 2019
Piperacillin with Tazobactam 4.5g Powder for Solution for Injection

PA1339/001/002 		 Piperacillin sodium & Tazobactam sodium Manufacturing delays

(multiple countries affected)		 Date of shortage:
January 2018

Expected return date:
Unknown at present		 Last updated:
12th July 2019
Pneumovax 23 Solution for Injection in Pre-filled Syringe

PA1286/055/002 		 Pneumococcal Polysaccharide Vacine  Unexpected increase in demand

(multiple countries affected)		 Date of shortage:
16th March 2020

Expected return date:
2021		 Last updated:
9th July 2020 
Propafenone hydrochloride 150mg Tablet

PA2315/116/001		 Propafenone hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
End of July 2020

Expected return date:
End of 2021 		 Last updated:
30th July 2020 
Propafenone hydrochloride 300mg Tablet

PA2315/116/002 		 Propafenone hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
End of July 2020

Expected return date:
End of 2021 		 Last updated:
30th July 2020 
Questran 4g Powder for Oral Suspension

PA2239/005/001 		 Colestyramine  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2019

Expected return date:
Q1 2021 		 Last updated:
22nd April 2020 
Quinine Sulphate 300mg Tablet

PA1986/052/001 		 Quinine sulphate  Manufacturing delays  Date of shortage:
Week commenicng 13th July 2020

Expected return date:
Awaiting update 		 Last updated:
4th August 2020 

HCP Letter
Rifadin 300mg Capsule

PA0540/066/002 		 Rifampicin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
19th June 2020

Expected return date:
Awaiting update 		 Last updated:
30th July 2020 
Rispone 6mg Film Coated Tablet

PA0711/106/005 		 Risperidone  Manufacturing delays  Date of shortage:
End of April 2020

Expected return date:
Awaiting update 		 Last updated:
23rd June 2020 
Salazopyrin 500mg Tablet

PA0822/196/002 		 Sulfasalazine  Manufacturing delays 

(multiple countries affected)		 Date of shortage:
30th June 2020

Expected return date:
End of October 2020 		 Last updated:
30th June 2020

HCP Letter 
Serlan 50mg Film Coated Tablet

PA0711/065/001 		 Sertraline  Manufacturing delays  Date of shortage:
22nd July 2020

Expected return date:
Unknown at present 		 Last updated:
29th July 2020 
Sofradex Ear/Eye Drops

PA0540/070/002 		 Framycetin, Gramicidin & Dexamethasone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid January 2020

Expected return date:
Unknown at present		 Last updated:
10th March 2020 
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
September 2020 		 Last updated:
3rd December 2019 
Sumatriptan 100mg Film Coated Tablet

PA2315/070/002
 		 Sumatriptan  Manufacturing delays  Date of shortage:
Early April 2020

Expected return date:
September 2020 		 Last updated:
17th April 2020 
Tefin 75mg Suppositories

PA1684/001/001 		 Ibuprofen  Manufacturing delays  Date of shortage:
August 2019

Expected return date:
Mid September 2020		 Last updated:
16th June 2020
Tefin 150mg Suppositories

PA1684/001/002 		 Ibuprofen  Manufacturing delays  Date of shortage:
August 2019

Expected return date:
Mid September 2020 		 Last updated:
16th June 2020 
Telfast 120mg Film Coated Tablet

PA0540/078/002 		 Fexofenadine  Unexpected increase in demand  Date of shortage:
Early August 2020

Expected return date:
Mid September 2020 		 Last updated:
31st July 2020 
Temozolomide 5mg Capsule

EU/1/09/606/001-002 		 Temozolomide  Unavailability of API  Date of shortage:
Mid June 2020

Expected return date:
October 2020 		 Last updated:
17th June 2020 
Teveten 400mg Film Coated Tablet

PA2010/017/001		 Eprosartan  Manufacturing delays  Date of shortage:
Mid June 2020

Expected return date:
Awaiting update		 Last updated:
17th July 2020 
Teveten 600mg Film Coated Tablet

PA2010/017/002 		 Eprosartan  Manufacturing delays  Date of shortage:
7th July 2020

Expected return date:
End of August 2020 		 Last updated:
10th July 2020 
Tipol 250mg Suppository

PA1684/002/003 		 Paracetamol  Manufactuirng delays  Date of shortage:
Early April 2020

Expected return date: 
Mid September 2020 		 Last updated:
16th June 2020 
Tipol 500mg Suppository

PA1684/002/004 		 Paracetamol  Manufacturing delays  Date of shortage:
Early April 2020

Expected return date:
Mid September 2020 		 Last updated:
16th June 2020 
Trandate 100mg Film Coated Tablet

PA1638/006/002 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
August 2020		 Last updated:
6th April 2020 
Trandate 200mg Film Coated Tablet

PA1638/006/003 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
August 2020		 Last updated:
6th April 2020
Ranitic 75mg Film Coated Tablet

PA0711/024/004 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
             
AHDMP Guidance for Prescribers
Ranitic 150mg Film Coated Tablet

PA0711/024/001 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers

AHDMP Guidance for Prescribers
 
Ranitic 300mg Film Coated Tablet

PA0711/024/002 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Ranitidine 150mg/10ml Oral Solution

PA22741/009/001 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Valsartan Actavis 40mg Film Coated Tablet 

PA1380/022/001		 Valsartan Active substance impurity

(multiple countries affected)
                        		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated: 
14th January 2020
Valsartan Actavis 80mg Film Coated Tablet

PA1380/022/002
     		 Valsartan Active substance impurity

(multiple countries affected)		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated:
14th January 2020
Valsartan Actavis 160mg Film Coated Tablet 

PA1380/022/003		 Valsartan Active substance impurity

(multiple countries affected)		 Date of shortage:
July 2018

Expected return date:
Awaiting update
 		 Last updated:
14th January 2020
Valsartan Teva 80mg Film Coated Tablet

PA0749/084/002 		 Valsartan Unexpected increase in demand

(multiple countries affected)		 Date of shortage:
July 2018

Expected return date:
December 2020		 Last updated:
17th July 2020
Valsartan Teva 160mg Film coated Tablet

PA0749/084/003 		 Valsartan  Unexpected increase in demand

(multiple countries affected)		 Date of shortage:
Awaiting update

Expected return date:
December 2020		 Last updated:
17th July 2020
Valsartan / Hydrochlorothiazide 160mg/ 25mg Film Coated Tablet

PA2315/181/003 		 Valsartan & Hydrochlorothiazide Active substance impurity

(multiple countries affected)		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated: 
21st February 2020
Vatan 40mg Film Coated Tablet

PA0711/183/001		 Valsartan  Active substance impurity

(multiple countries affected) 		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated:
18th November 2019
Vatan 80mg Film Coated Tablets

PA0711/183/002 		 Valsartan  Active Substance Impurity

(multiple countries affected) 		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated:
18th November 2019
Vatan 160mg Film Coated Tablets

PA0711/183/003 		 Valsartan Active Substance impurity

(multiple countries affected) 		  
Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated:
18th November 2019
Vedixal 37.5mg Tablet

PA0711/161/002 		 Venlafaxine  Manufacturing delay  Date of shortage:
22nd April 2020

Expected return date:
12th August 2020		 Last updated:
23rd June 2020 
Venex XL 37.5mg Prolonged-Release Capsule

PA0126/285/001		  Venlafaxine Manufacturing delay Date of shortage:
07/05/2020

Expected return date:
Unknown at present		 Last updated:
7th May 2020 
Venex XL 150mg Prolonged-Release Capsule

PA0126/285/003 		 Venlafaxine  Manufacturing delay  Date of shortage:
Mid May 2020

Expected return date:
Unknown at present 		 Last updated:
15th May 2020 
Verap 120mg Prolonged Release Tablet

PA0711/016/004 		 Verapamil  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Early December 2020		 Last updated:
28th July 2020 
Visudyne 15mg Powder for Solution for Infusion

EU/1/00/140/001		 Vertiporfin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
End of July 2020

Expected return date:
February 2021 		 Last updated:
30th July 2020
 
Zaditen 1mg Tablet

PA2206/004/002 		 Ketotifen  Manufacturing delays  Date of shortage:
Early 2020

Expected return date:
Unkown at present 		 Last updated:
5th June 2020 
Zoely 2.5mg/1.5mg Film Coated Tablet 

EU/1/11/690/001		 Nomegestrol acetate & Esradiol  Unavailability of API

(multiple countries affected) 		 Date of shortage:
Early August 2019

Expected return date:
End of 2020		 Last updated:
27th January 2020
 
HCP Letter
Zolmitriptan 2.5mg Orodispersible Tablet

PA1380/035/003 		 Zolmitriptan  Manufacturing delays  Date of shortage:
Mid May 2020

Expected return date:
September 2020 		 Last updated:
11th May 2020 

Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL




Contact us:

Medicinal Product Shortages Unit
Health Products Regulatory Authority 
Kevin O’Malley House
Earlsfort Terrace,
Dublin 2
Tel: +353 1 676 4971
Fax: +353 1 676 7836
shortages@hpra.ie