Medicinal Product Shortages

The HPRA is responsible for co-ordinating the management of shortages of human medicines on the Irish market. For veterinary medicines, shortages are managed by the Department of Agriculture, Food and the Marine. 

The HPRA works with a variety of stakeholders including manufacturers, wholesale distributors, marketing authorisation holders, healthcare professionals, the Health Service Executive, patients and representative groups to respond to potential shortages and reduce the impact of shortages on patients.

The definition of a shortage is when the supply of a medicinal product is inadequate to meet the needs of the patient. 

The HPRA, in collaboration with stakeholders, has published a framework for a multi-stakeholder approach to handling shortages of human medicinal products. The aim of the framework is to help prevent shortages from occurring and to reduce the impact of shortages on patients by co-ordinating the management of potential or actual shortages as they arise. You can see the shortages case study on Adrenaline auto-injectors (AAIs) as an example of how the framework operates in practice. 


Information on reporting shortages for:

Wholesale Distributors and Manufacturers

Patients and Healthcare Professionals

Please complete the Report of medicinal product shortage affecting the Irish market from patients and healthcare professionals form and return to  shortages@hpra.ie. When completing this form, please include as much information as possible.

Veterinary Medicines

 

Current and resolved shortages

The HPRA publishes a list of shortages currently affecting the Irish market that have been notified to us and that may have a medium or high impact on patients. This list can be found below. More information on the impact level can be found in the framework for a multi-stakeholder approach to handling shortages of human medicinal products.

The HPRA maintains a consolidated list of resolved shortages for a period of six months. Details of shortages that have been resolved in the last six months can be found here.


RoActemra supply disruptions

The marketing authorisation holder (MAH; Roche) notified the HPRA of a shortage of tocilizumab-containing medicines caused by increased global demand for the active ingredient. Tocilizumab products in Ireland are marketed under the brand name RoActemra. The shortage is not specific to the Irish market and is global in nature, affecting multiple countries.

Due to the increased global demand, the company has advised of intermittent supply of RoActemra medicines until the end of 2021. Please see Roche’s communication for additional details (HCP letter).

The HPRA is in regular contact with the company concerning the restoration of supply to patients in Ireland. The HPRA Shortages webpage is updated with the most current information on expected resupply dates.


Please use search function below to find relevant product or active ingredient

 
Product name Active ingredient Reason for shortage Date of shortage
Additional information
Abstral 100mcg Sublingual Tablets

PA2288/004/002
 Fentanyl  Manufacturing delay 

(multiple countries affected) 
Date of shortage: 
3rd September 2021 

Expected return date: 
Week commencing 1st October 2021
Last updated: 
22nd October 2021
Abstral 200mcg Sublingual Tablets

PA2288/004/003
Fentanyl Manufacturing delays 

(multiple countries affected)
Date of shortage:
15th August 2021

Return date: 
Week commencing 25th October 2021
Last updated: 
22nd October 2021
Abstral 300mcg Sublingual Tablets

PA2288/004/004
Fentanyl  Manufacturing delays 

(multiple countries affected) 
Date of shortage: 
5th October 2021

Expected return date: 
Week commencing 25th October 2021
Last updated: 
22nd October 2021
Abstral 400mcg Sublingual Tablets

PA2288/004/005
Fentanyl  Manufacturing delays 

(multiple countries affected)
Date of shortage: 
4th October 2021

Expected return date: 
Early December 2021
Last updated: 
22nd October 2021
Abstral 600mcg Sublingual Tablets

PA2288/004/006
Fentanyl   Manufacturing delay 

(multiple countries affected)
Date of shortage: 
2nd September 2021 

Expected return date:
 
Week commencing 25th October 2021
Last updated: 
22nd October 2021
Abstral 700mcg Sublingual Tablets

PA2288/004/007
Fentanyl Manufacturing delay 

(multiple countries affected) 
Date of shortage: 
2nd September 2021

Expected return date: 
Early December 2021
Last updated: 
22nd October 2021
Adizem-XL 180mg Prolonged Release Capsules

PA1688/001/005
Dilitazem  Manufacturing delays Date of shortage: 
1st October 2021

Expected return date: 
November 2021 
Last updated: 
27th September 2021
Amitriptyline 25mg Film Coated Tablets

PA0126/041/001
Amitriptyline
API unavailability Date of shortage: 
2nd September 2021 

Expected return date: 
Late October 2021
Last updated: 
7th September 2021 

HCP letter
Astilin 10mg Tablets

PA23163/001/001
Amitriptyline  Awaiting update Date of shortage: 
27th August 2021

Expected return date: 
29th October 2021
Last updated: 
5th October 2021

HCP letter
Ativan 4mg/ml Solution for Injection

PA0822/090/002 
Lorazepam  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Early August 2020

Expected return date:
Unknown at present
Last updated:
14th May 2021 
 
HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 
Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 
Date of shortage:
1st October 2019

Expected return date:
2022
Last updated:
3rd February 2021
Becotide Evohaler 50mcg, Pressurised Inhalation Solution

PA1077/042/006
Beclometasone Manufacturing delays 

(multiple countries affected)
Date of shortage: 
Week commencing 11th October 2021 

Expected return date: 
Early November 2021
Last updated: 
4th October 2021 
Bendroflumethiazide 2.5mg Tablets

PA22749/021/001
Bendroflumethiazide
 Regulatory issue Date of shortage:
3rd September 2021

Expected return date:
 
Awaiting update
Last updated: 
1st October 2021
Beromun 1mg Powder for Solution for Infusion

EU/1/99/097/001 
Tasonermin  Manufacturing delays

(multiple countries affected) 
Date of shortage:
December 2020

Expected return date:
November 2021
Last updated:
1st June 2021
Calcium Acetate 500mg Tablets

PA0281/063/001
Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
Late December 2021
Last updated: 
30th September 2021
Canesten HC 1% w/w + 1% w/w Cream

PA1410/040/002
Clotrimazole & Hydrocortisone  Manufacturing delays Date of shortage: 
30th September 2021 

Expected return date:
5th November 2021
Last updated: 
22nd September 2021
Catapres Tablets 100mcg

PA2256/003/001
 Clonidine Manufacturing delays

(multiple countries affected)
Date of shortage: 
25th July 2021

Expected return date: 
25th October 2021
Last updated: 
21st June 2021 
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
Varenicline 
Quality issue

(multiple countries affected)
Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 
Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
Varenicline Quality issue

(multiple countries affected)
Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 
Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
Varenicline 
Quality issue 

(multiple countries affected)
Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 
Last updated: 
18th June 2021

HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution

PA2299/005/001
Chlorhexidine acetate & cetrimide
Unexpected increase in demand Date of shortage: 
September 2021 

Expected return date: 
Mid November 2021 
Last updated: 
20th October 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution

PA0281/124/001 
Chlorpromazine hydrochloride  Manufacturing delays  Date of shortage:
End of February 2021

Expected return date:
End January 2022
Last updated:
5th October 2021
 
HCP letter
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes 

PA0540/097/008
Enoxaparin sodium  API unavailability   Date of shortage: 
22nd October 2021 

Expected return date: 
Unknown at present
Last updated: 
13th October 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion

PA1457/001/001
Amoxicillin & Clavulanic acid
Manufacturing delays Date of shortage: 
13th October 2021 

Expected return date: 
Awaiting update
Last updated: 
18th October 2021 
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion

PA1457/001/002
Amoxicillin & clavalunic acid Unexpected increase in demand Date of shortage:
5th February 2020

Expected return date:
Awaiting update
Last updated:
19th October 2021
CoAprovel 300mg/12.5mg Tablets

EU/1/98/086/004
Irbesartan & Hydrochlorothiazide  Shipping delay  Date of shortage: 
5th November 2021

Expected return date: 
Late November 2021  
Last updated: 
22nd October 2021 
Cyklokapron 100 mg/mL Solution for Injection/Infusion

PA0822/117/001
Tranexamic acid Manufacturing delays Date of shortage: 
Week commencing 18th October 2021

Expected return date
Week commencing 15th November 2021 
Last updated: 
5th October 2021 
Deslor 5mg Film Coated Tablets

PA0711/202/001
Desloratidine Awaiting information   Date of shortage: 
19th September  2021  

Expected return date: 
Late December 2021
Last updated: 
October 2021 
Desmopressin 100mcg/ml Nasal Drop Solution

PA1009/001/001 
Desmopressin  Manufacturing delays due to quality issue

(multiple countries affected) 
Date of shortage:
Mid December 2020

Expected return date:
2022 
Last updated:
11th December 2020 
Desmospray Desmopressin Nasal Spray

PA1009/005/001 
Desmopressin  Quality issue

(multiple countries affected) 
Date of shortage:
22nd July 2020

Expected return date:
2022 
Last updated:
11th December 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 
Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present
Last updated:
30th March 2021 
Dioralyte Blackcurrant Powder for Oral Solution (20 pack)

PA0540/098/001
Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate  Unexpected increase in demand  Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
Last updated: 
30th September 2021
Dioralyte Citrus Powder for Oral Solution
(20 pack)

PA0540/098/002
Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
Last updated: 
30th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution
(6 pack)

PA0540/194/002
Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
Last updated: 
30th September 2021
Doxatan 4mg Tablets

PA0126/202/003 
Doxazosin  Manufacturing delay   Date of shortage: 
4th October 2021

Expected return date:
Week commencing 1st November 2021
Last updated: 
20th October 2021
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 
Adrenaline  Quality issue

(multiple countries affected) 
Date of shortage:
30th September 2019

Expected return date:
Unknown at present 
Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 
Adrenaline  Quality issue

(multiple countries affected) 
Date of shortage:
30th September 2019

Expected return date:
Unknown at present 
Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 
Adrenaline  Quality issue

(multiple countries affected) 
Date of shortage:
30th September 2019

Expected return date:
Unknown at present 
Last updated:
18th December 2020

Alternatives are available 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005
Phenytoin Manufacturing delays

(multiple countries affected)
Date of shortage:
Early November 2019

Expected return date:
Unknown at present
Last updated:
4th June 2020
 
HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion

PA1852/002/001 
Esomeprazole  Unavailability of API  Date of shortage:
Early October 2020

Expected return date:
Late November 2021
Last updated:
12th October 2021
Ezetimibe Rowa 10mg Tablets

PA0074/074/001
Ezetimibe Awaiting information  Date of shortage: 
19th October 2021 

Expected return date: 
Late November 2021 
Last updated: 
21st October 2021
Ezetimibe Teva 10mg tablets

PA1986/012/001
Ezetimibe  Quality Issue  Date of shortage: 
18th October 2021 

Expected return date: 
13th December 2021
Last updated: 
4th October 2021
Ezetimibe 10mg tablets

PA0577/198/001
Ezetimibe
Manufacturing delays  Date of shortage: 
Late August 2021 

Expected return date: 
Early November 2021
Last updated: 
4th October 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets

PA0711/262/001
Ezetimibe & simvastatin
Manufacturing delays  Date of shortage: 22nd July 2021

Expected return date: 
October 2021
Last updated: 
20th September 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003
Ezetimibe & simvastatin
Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date: 
End November 2021
Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets

PA1986/067/003
Ezetimibe & simvastatin
API unavailability

(multiple countries impacted) 
Date of shortage: 
30th August 2021 

Expected return date: 
Awaiting update
Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets

PA0126/281/002

Ezetimibe & simvastatin
Manufacturing delays   Date of shortage: 
Week commencing 20th September 2021

Expected return date: 
Unknown at present
Last updated: 
20th September 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets

PA0126/281/004
Ezetimibe & simvastatin
Manufacturing delays Date of shortage: 
Week commencing 20th September 2021

Expected return date:  
Unknown at present
Last updated: 
20th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection

PA0822/198/002
Folinic Acid  Unexpected increase in demand Date of shortage: 
Week commencing 27th September 2021

Expected return date: 
Awaiting update
Last updated:
18th October 2021
Fomicyt 40mg/ml Powder for Solution for Infusion

PA1972/001/001
Fosfomycin sodium Regulatory issue  Date of Shortage: 
October 2021 

Expected return date: 
Unknown at present
Last updated: 
12th October 2021
Geodon 80mg Hard Capsules

PA23055/015/004
Ziprasidone  Unexpected increase in demand Date of shortage: 
31st August 2021

Expected return date: 
21st October 2021
Last updated: 
8th September 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension

PA1142/014/001
Gentamicin & Hydrocortisone Unavailability of API 

(multiple countries affected)
Date of shortage
23rd August 2021

Expected return date:
Late November 2021
Last updated: 
9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 
Hydromorphone  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid June 2020

Expected return date:
February 2022
Last updated:
18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 
Hydromorphone  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid August 2020

Expected return date:
February 2022
Last updated:
18th October 2021
Imodium Plus 2mg/125mg Tablets

PA0330/050/001
Loperamide & simeticone  Manufacturing delay  Date of shortage: 
11th October 2021 

Expected return date:
Week commencing 22nd November 2021
Last updated: 
20th October 2021
Innohep 8,000 IU in 0.4 ml, Solution for Injection

PA0046/060/012
Tinzaparin sodium
Manufacturing delays Date of shortage: 
24th August 2021

Expected return date: 
Awaiting update
Last updated: 
18th October 2021

HCP letter

Innohep 10,000 IU/ml Solution for Injection

PA0046/060/002
Tinzaparin sodium
Unexpected increase in demand

(multiple countries affected)
Date of shortage: 
20th September 2021

Expected return date: 
Mid-November 2021
Last updated: 
23rd September 2021
Instanyl 50mcg Nasal Spray 

EU/1/09/531/010-013
Fentanyl  Quality issue 
(multiple countries affected)
Date of shortage: 
1st August 2021 

Expected return date: 
February 2022
Last updated: 
20th August 2021
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
Fentanyl  Quality issue

(multiple countries affected) 
Date of shortage: 
2nd April 2021

Expected return date: 
February 2022
Last updated
20th August 2021
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
Fentanyl  Quality issue

(multiple countries affected) 
Date of shortage
2nd April 2021

Expected return date: 
February 2022
Last updated:
20th August 2021
Invokana 300mg Film Coated Tablets

EU/1/13/884/005-008
Canagliflozin
Unexpected increase in demand  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021 
Last updated: 
12th October 2021
Letrozole 2.5mg Film Coated Tablets

PA2315/109/001
Letrozole  Awaiting information   Date of shortage: 
Week commencing 25th October 2021

Expected return date: 
End November 2021
Last updated: 
18th October 2021 
Letrozole 2.5mg Film Coated Tablets

PA0126/198/001
Letrozole  Manufacturing delays  Date of shortage: 
22nd October 2021 

Expected return date: 
22nd December 2021
Last updated: 
18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets

PA0749/085/001
Letrozole  API unavailability 

(multiple countries affected) 
Date of shortage: 
Week commencing 9th August 2021

Expected return date: 
January 2021
Last updated: 
5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet

PA0711/051/002 
Lisinopril & Hydrochlorothiazide  Manufacturing delays  Date of shortage:
8th September 2020

Expected return date:
Week commencing 1st November 2021
Last updated:
20th October 2021
Losartan 50mg Tablet 

PA2315/059/002 
Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
Unknown at present 
Last updated:
13th April 2021
Losartan 100mg Tablet

PA2315/059/003 
Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present
Last updated:
13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film-Coated Tablets

PA0749/026/001
Losartan & Hydrochlorothiazide
 Quality issue Date of shortage: Late October 2021  

Expected return date: 
March 2022
Last updated: 
22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets

PA0749/026/002
Losartan & Hydrochlorothiazide
Quality issue  Date of shortage: 
Late October 2021

Expected return date: 

March 2022
Last updated: 
22nd October 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 
Date of shortage: 
1st July 2021

Expected return date: 
Unknown at present 
Last updated: 
24th September  2021 
Mefac 250mg Capsule

PA0074/015/001 
Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present
Last updated:
23rd April 2021
 
Metaraminol 10mg/ml Solution for Injection or Infusion 

PA22893/001/001
Metaraminol  Awaiting update Date of shortage: 
Early April 2021 

Expected return date:
Awaiting update
Last updated: 
30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution

PA23081/008/001
Metformin  Regulatory Issue Date of shortage
13th August 2021

Expected return date: 
Unknown at present
Last updated: 
10th August 2021
Mydrilate 1.0% w/v Eye Drops

PA22709/003/002
Cyclopentolate Manufacturing delay  Date of shortage:
Early September 2021

Expected return date: 
Mid-October 2021
Last updated: 
27th September 2021 
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion 

PA0073/111/002
Naloxone Manufacturing delay  Date of shortage: 
18th October 2021

Expected return date: 
3rd December 2021 
Last updated: 
19th October 2021
Nanocis 0.24mg Kit for Radiopharmaceutical Preparation

PA0677/006/001
Rhenium sulphide
Awaiting information  Date of shortage: 
Week commencing 20th September 2021 

Expected return date: 
Week commencing 8th November 2021
Last updated: 
1st October 2021
Odrik 2mg Hard Capsule

PA2010/005/003
Trandolapril
Manufacturing delays Date of shortage: 
5th October 2021

Expected return date: 
Late October 2021 
Last updated: 
28th September 2021
Oramox 125mg/5ml Powder for Oral Suspension

PA0298/019/001
Amoxicillin
Unexpected increase in demand  Date of shortage:
22nd October 2021 

Expected return date: 
Unknown at present 
Last updated: 
19th October 2021 
OxyContin 5mg Prolonged Release Tablets 

PA1688/005/001
 Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021
Last updated:
12th October 2021
OxyNorm Dispersa 5mg Orodispersible Tablets

PA1688/006/007
Oxycodone  Unexpected increase in demand  Date of shortage: 
5th October 2021 

Expected return date: 
4th November 2021
Last updated: 
18th October 2021
OxyNorm Dispersa 10mg Orodispersible Tablets

PA1688/006/008
Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date:
Unknown at present 
 Last updated: 
12th October 2021
OxyNorm Dispersa 20mg Orodispersible Tablets

PA1688/006/009
Oxycodone Manufacturing delays  Date of shortage: 
26th October 2021 

Expected return date:
February 2022
Last updated: 
20th October 2021 
Palexia 4mg/ml Oral Solution

PA2242/012/010 
Tapentadol hydrochloride  Quality issue

(multiple countries affected) 
Date of shortage:
15th February 2021

Expected return date:
Unknown at present 
Last updated: 
22nd February 2021
Paralief 500mg Tablets 

24 pack only

PA0126/020/001
Paracetamol API unavailability  Date of shortage: 
Week commencing 23rd August 2021

Expected return date: 
27th October 2021
Last updated: 
28th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w

PA0278/017/002
Hydrocortisone & Lidocaine Hydrochloride  Manufacturing delays  Date of shortage:
February 2021

Expected return date:
January 2022
Last updated: 
8th April 2021
Qlaira Film Coated Tablets

PA1410/058/001
 Estradiol API unavailability  Date of shortage: 
Mid November 2021

Expected return date: 
Q2 2022
Last updated: 
7th October 2021

HCP letter
Questran 4g Powder for Oral Suspension

PA2239/005/001 
Colestyramine  Manufacturing delays

(multiple countries affected) 
Date of shortage:
Mid June 2019

Expected return date:
January 2022
Last updated:
30th March 2021 
Rifater 50mg/300mg/120mg Tablets

PA0822/143/002
Isoniazid & Pyrazinamide & Rifampicin Quality issue

(multiple countries impacted)
Date of shortage: 
23rd July 2021

Expected return date: 
26th October 2021
Last updated:
18th October 2021

AMRIC guidance V3
Rosuvastatin 5mg Film Coated Tablets

PA2315/068/001
Rosuvastatin Quality issue  Date of shortage:
27th August 2021

Expected return date: 
Q2 2022
 Last updated: 
30th August 2021
Rosuvastatin 10mg Film Coated Tablets

PA2315/068/002
Rosuvastatin  Quality issue Date of shortage: 
27th August 2021 

Expected return date: 
Q2 2022 
Last updated: 
30th August 2021 
Rosuvastatin 20mg Film Coated Tablets

PA2315/068/003
Rosuvastatin   Distribution issue Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
Last updated: 
21st October 2021 
Rosuvastatin 40mg Film Coated Tablets

PA2315/068/004
Rosuvastatin   Distribution issue
Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
Last updated: 
21st October 2021 
Sevelamer Carbonate 800mg Film Coated Tablets

PA0577/205/001
Sevelamer  Manufacturing delays Date of shortage: 
Late October

Expected return date: 
Unknown at present  
Last updated: 
22nd October 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 
Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Mid-December 2021
Last updated:
22nd October 2021
Stesolid Rectal Solution 5mg

PA2315/137/001
Diazepam  Manufacturing delays Date of shortage: 
Late August 2021

Expected return date: 
November 2021
Last updated: 
12th August 2021
Stesolid Rectal Solution 10mg

PA2315/137/002
 Diazepam Manufacturing delays  Date of shortage: 
Week commencing 19th July 2021. 

Expected return date: 
November 2021
Last updated: 
21st July 2021
Targin 20mg/10mg Prolonged Release Tablets

PA1688/010/001
Oxycodone & Naloxone  Shipping delays Date of shortage: 
27th September 2021 

Expected return date: 
28th October 2021
Last updated: 
22nd October 2021
Telmisartan Rowa 40mg Tablets

PA0074/078/002
Telmisartan  Unexpected increase in demand  Date of shortage: 
7th September 2021

Expected return date: 
Late November 2021
 Last updated: 
20th October 2021
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
Alendronic acid API unavailability  Date of shortage: 
6th September 2021 

Expected return date: 
Late November 2021 
Last updated: 
23rd August 2021 
Tracrium 10 mg/ml, Solution for injection or infusion

(25ml ampoule)

PA1691/029/002
Atracurium  Unexpected increase in demand Date of shortage: 
24th September 2021 

Expected return date: 
20th November 2021 
Last updated: 
24th September 2021
Trandate 200mg Film Coated Tablet

PA1638/006/003 
Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 
Date of shortage:
July 2019

Expected return date:
End October 2021
Last updated:
11th October 2021
TPN – various B. Braun products
Various  Manufacturing delays  Date of shortage: 
4th October 2021

Expected return date: 
Unknown at present
Last updated: 
5th October 2021

HCP letter
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment

PA22650/004/001
Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride  Regulatory issue Date of shortage: 
Late September 2021

Expected return date: 
Late December 2021
Last updated: 
15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets

PA1688/011/001
Theophylline  Manufacturing delays  Date of shortage: 
Week commencing 11th October 2021 

Expected return date: 
2nd December 2021 
Last updated: 
18th October 2021
Valoid 50mg Tablets

PA1142/001/002
Cyclizine  Manufacturing delays  Date of shortage: 
1st November 2021 

Expected return date: 
Unknown at present
Last updated: 
18th October 2021
Visudyne 15mg Powder for Solution for Infusion

EU/1/00/140/001
Verteporfin  Manufacturing delay  Date of shortage: 
May 2021

Expected return date: 
January 2022
Last updated: 
28th July 2021

HCP letter
Voriconazole Accord 50mg Film Coated Tablets 

EU/1/13/835/001
Voriconazole  Manufacturing delay Date of shortage: 
10th September 2021

Expected return date: 
Awaiting update
Last updated: 
21st October 2021
Zerbaxa 1g/0.5g Powder for Concentrate for Solution for Infusion

EU/1/15/1032/001 
Ceftolozone & Tazobactam  Quality issue

(multiple countries affected) 
Date of shortage:
18th December 2020

Expected return date:
Unknown at present 
Last updated:
4th March 2021 
Xomolix 2.5mg/ml Solution for Injection

PA2288/003/002
Droperidol  Quality issue

(multiple countries affected)
Date of shortage: 
29th May 2021

Expected return date: 
Unknown at present  
Last updated: 
2nd July 2021

Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL



Date of shortage: 
2nd July 2021

Expected return date
Unknown at present  
Date of shortage: 
2nd July 2021

Expected return date
Unknown at present  

Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 


Contact us:

Medicinal Product Shortages Unit
Health Products Regulatory Authority 
Kevin O’Malley House
Earlsfort Terrace,
Dublin 2
Tel: +353 1 676 4971
Fax: +353 1 676 7836
shortages@hpra.ie