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Medicinal Product Shortages

The HPRA is responsible for co-ordinating the management of shortages of medicines on the Irish market. The HPRA works with a variety of stakeholders including manufacturers, wholesale distributors, marketing authorisation holders, healthcare professionals, the Health Service Executive, patients and representative groups to respond to potential shortages and reduce the impact of shortages on patients.

The definition of a shortage is when the supply of a medicinal product is inadequate to meet the needs of the patient. 

The HPRA, in collaboration with stakeholders, has published a framework for a multi-stakeholder approach to handling shortages of human medicinal products. The aim of the framework is to help prevent shortages from occurring and to reduce the impact of shortages on patients by co-ordinating the management of potential or actual shortages as they arise. You can see the shortages case study on Adrenaline auto-injectors (AAIs) as an example of how the framework operates in practice. 


Information on reporting shortages for:

Marketing Authorisation Holders

Please complete the  Notification of medicinal product shortage from marketing authorisation holder form and return to  shortages@hpra.ie and to the HSE Corporate Pharmaceutical Unit.

Wholesale Distributors and Manufacturers

Please complete the  Report of Medicinal Products Shortages from Wholesale Distributors and Manufacturers form and return this form to  shortages@hpra.ie.

Patients and Healthcare Professionals

Please complete the  Report of a Medicinal Product Shortage from Patients and Healthcare Professionals form and return to  shortages@hpra.ie. When completing this form, please include as much information as possible.


Current and resolved shortages

The HPRA publishes a list of shortages currently affecting the Irish market that have been notified to us and that may have a medium or high impact on patients. This list can be found below. More information on the impact level can be found in the framework for a multi-stakeholder approach to handling shortages of human medicinal products.

The HPRA maintains a consolidated list of resolved shortages for a period of six months. Details of shortages that have been resolved in the last six months can be found here.
 

Hormone replacement therapy (HRT) shortages

HRT shortages have impacted multiple countries over the past year and are not restricted to Ireland. While there are shortages of some specific brands, alternatives are available to meet patient need. The suppliers have stated that the causes of the shortages relate to both active substance availability and manufacturing delays. It is not related to Brexit. The HPRA continues to be in frequent contact with the suppliers to maintain efforts to expedite re-supply as soon as possible. The HPRA website will be will be kept up to date as additional information becomes available.

 

If a patient has any concerns about their medicine, the HPRA advises that they should discuss their treatment a doctor or pharmacist.


Please use search function below to find relevant product or active ingredient

 
Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Accupro 20mg Film Coated Tablet

PA0822/007/003 		 Quinapril hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid March 2019

Expected return date:
June 2020		 Last updated:
24th April 2020
 

 
Accuretic 20/12.5mg Film Coated Tablet

PA0822/008/002 		 Quinapril hydrochloride & Hydrochlorothiazide  Manufacturing delays 

(multiple countries affected)		 Date of shortage:
Early January 2019

Expected return date:
June 2020		 Last updated:
24th April 2020
 

 
           
Adalat LA 20mg Prolonged Release Tablet

PA1410/025/005		 Nifedipine  Manufacturing delays

(multiple countries affected)		 Date of shortage:
November 2017
 
Expected return date:
Not before 2021		 Last updated:
29th November 2019
 
Adalat LA 30mg Prolonged Release Tablet

PA1410/025/006		 Nifedipine  Manufacturing delays

(multiple countries affected)		 Date of shortage:
24th June 2018

Expected return date:
Not before 2021
 Last updated:
29th November 2019 
 
Adalat LA 60mg Prolonged Release Tablet

PA1410/025/007 		 Nifedipine Manufacturing delays

(multiple countries affected)		 Date of shortage:
September 2018

Expected return date:
Not before 2021		 Last updated:
29th November 2019
 
Alendronate/Colecalciferol Teva 70mg/5600IU Tablet

PA0749/196/002 		 Alendronate & Colecalciferol  Manufacturing delays  Date of shortage:
January 2019

Expected return date:
Q3 2020 		 Last updated:
14th May 2020 
Amisulpride 50mg Tablet

PA0577/182/001 		 Amisulpride  Manufacturing delays  Date of shortage:
July 2019

Expected return date:
End of May 2020 		 Last updated:
28th April 2020 
Amisulpride 200mg Tablet

PA0577/182/002 		 Amisulpride  Manufacturing delays  Date of shortage:
February 2019

Expected return date:
End of May 2020		 Last updated:
28th April 2020 
Amoxil Vials 500mg Powder for Solution for Injection or Infusion

PA1077/033/004 		 Amoxicillin  Unavailability of API

(multiple countries affected) 		 Date of shortage:
25th February 2020

Expected return date:
Early July 2020 		 Last updated:
1st May 2020 
Areloger 15mg Film Coated Tablet

PA0577/057/002 		 Meloxicam  Manufacturing delays  Date of shortage:
Early August 2019

Expected return date:
August 2020		 Last updated:
18th February 2020 
Arthrotec 50 Modified Release Tablet

PA0822/112/001 		 Diclofenac & Misoprostol  Manufactuirng delays  Date of shortage:
20th April 2020

Expected return date:
Early June 2020 		 Last updated:
15th April 2020 

HCP Letter
Atecor CT 50mg/12.5mg Tablet

PA0711/020/001 		 Chlortalidone & Atenolol  Unexpected increase in demand  Date of shortage:
Early March 2020

Expected return date:
Awaiting update 		 Last updated:
19th May 2020 
Atecor CT 100mg/25mg Tablet

PA0711/020/002 		 Chlortalidone & Atenolol  Unexpected increase in demand  Date of shortage:
Early March 2020

Expected return date:
End of June 2020		 Last updated:
19th May 2020 
Atenomel 50mg Tablet

PA0126/069/001 		 Atenolol  Unexpected increase in demand  Date of shortage:
End of April 2020

Expected return date:
Early June 2020 		 Last updated:
28th April 2020 
Atorvastatin 80mg Tablet

PA0126/271/004		 Atorvastatin Manufacturing delays Date of shortage:
11th May 2020

Expected return date:
5th August 2020		 Last updated:
13th May 2020 
Axsain 0.075% w/w Cream

PA0827/004/001 		 Capsaicin  Manufacturing delays 

(multiple countries affected)		 Date of shortage:
Mid June 2019

Expected return date:
July 2020		 Last updated:
21st  May 2020 
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
Unknown at present 		 Last updated:
7th November 2019 
Blopress 8mg Tablet

PA2229/001/004
  Candesartan Manufacturing delays

(multiple countries affected)		 Date of shortage:
11th May 2020

Expected return date:
28th May 2020		 Last updated:
11th May 2020 
Candist 8mg Tablet

PA0126/206/002 		 Candesartan  Unexpected increase in demand

 		 Date of shortage:
End of April 2020

Expected return date:
Mid August 2020		 Last updated:
24th April 2020 
Canesten Combi 500mg Pessary & 2% Cream

PA1410/039/001 		 Clotrimazole  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
April 2020

Expected return date:
August 2020 		 Last updated:
8th May 2020

HCP Letter
Canesten Duopack - 100mg Pessary & 1% w/w Cream

PA1410/039/005 		 Clotrimazole  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
February 2018

Expected return date:
August 2020 		 Last updated:
7th May 2020
             
HCP Letter
Canesten 200mg Pessary

PA1410/039/008 		 Clotrimazole  Manufacturing delay

(multiple countries affected) 		 Date of shortage:
February 2018

Expected return date:
August 2020		 Last updated:
7th May 2020
             
HCP Letter
Canesten 500mg Pessary

PA1410/039/009 		 Clotrimazole  Manufacturing delay

(multiple countries affected) 		 Date of shortage:
January 2018

Expected return date:
August 2020		 Last updated:
7th May 2020
                         
HCP Letter
Celecoxib 100mg Capsule

PA0711/241/001 		 Celecoxib  Manufacturing delays  Date of shortage:
Mid May 2020

Expected return date:
Early July 2020 		 Last updated:
19th May 2020 
Celecoxib 200mg Capsule

PA2315/228/002 		 Celecoxib  Manufacturing delays  Date of shortage:
February 2020

Expected return date:
Early June 2020 		 Last updated:
11th May 2020 
Cimeldine 400mg Film Coated Tablet

PA0126/077/002 		 Cimetidine  API delay  Date of shortage:
9th December 2019

Expected return date:
6th July 2020 		 Last updated:
24th April 2020 
Ciprofloxacin Teva 250mg Film Coated Tablet


PA0749/031/002 		 Ciprofloxacin  Manufacturing delays  Date of shortage:
Early September 2019

Expected return date:
Q3 2020		 Last updated:
17th April 2020
Ciproxin 500mg Tablet

PA1410/028/003 		 Ciprofloxacin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
September 2018

Expected return date:
End of May 2020 		 Last updated:
18th March 2020
 
HCP Letter
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection and Infusion

PA1457/001/001		 Amoxicillin & clavalunic acid Unexpected increase in demand Date of shortage:
24th May 2019

Expected return date:
Unknown at present		 Last updated:
11th March 2020 
Co-Amoxiclav 1000mg/200mg Powder for solution for injection/infusion

PA1339/005/002		 Amoxicillin & clavalunic acid Unexpected increased demand Date of shortage:
5th February 2020

Expected return date:
Unknown at present
 Last updated:
11th March 2020 
Colofac 135mg Tablet

PA2010/007/001 		 Mebeverine  Manufacturing delays  Date of shortage:
Early May 2020

Expected return date:
Mid June 2020 		 Last updated:
5th May 2020 
Diaglyc 30mg Modified Release Tablet

PA0749/076/001 		 Gliclazide  Manufacturing delays  Date of shortage:
20th May 2020

Expected return date:
Early July 2020 		 Last updated:
21st May 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present 		 Last updated:
1st May 2020 
Efexor 37.5mg prolonged release capsules, hard

PA0822/072/001		 Venlafaxine hydrochloride Manufacturing delays Date of shortage:
27th April 2020

Expected return date:
Mid June 2020		 Last updated:
30th April 2020 
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
30th September 2019

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
30th September 2019

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
30th September 2019

Alternatives are available 
Enap 10mg Tablet

PA0711/028/002 		 Enalapril  Manufacturing delay  Date of shortage:
End of April 2020

Expected return date:
Unknown at present 		 Last updated:
8th May 2020 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005		 Phenytoin Manufacturing delays

(multiple countries affected)		 Date of shortage:
Early November 2019

Expected return date:
Unknown at present		 Last updated:
19th March 2020
 
HCP Letter
Erythrocin 250mg Tablet

PA1142/008/002 		 Erythrocin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2019

Expected return date:
29th May 2020		 Last updated:
4th February 2020 
Erythrocin 500mg Tablet

PA1142/008/003 		 Erythrocin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
End of February 2020

Expected return date:
End of June 2020
 Last updated:
12th May 2020 
Erythroped PI SF 125mg/5ml Granules for Oral Suspension

PA1142/006/002 		 Erythromycin  Manufacturing delays 

(multiple countries affected)		 Date of shortage:
End of June 2019

Expected return date:
26th May 2020 		 Last updated:
4th February 2020 
Erythroped SF 250mg/5ml Granules for Oral Suspension

PA1142/006/001 		 Erythromycin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid November 2019

Expected return date:
12th June 2020		 Last updated:
4th February 2020 
Estradot 75mcg/day Transdermal Patch

PA0896/010/003 		 Estradiol  Manufcaturing delays  Date of shortage:
29th April 2020

Expected return date:
Mid June 2020 		 Last updated:
30th April 2020 
Evorel 50mcg Transdermal Patch

PA22668/008/001 		 Estradiol  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
October 2019

Expected return date:
July 2020 		 Last updated:
19th May 2020
             

 
Evorel Conti 50mcg/170mcg Transdermal Patch

PA22668/009/001 		 Estradiol & Norethisterone Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early January 2020

Expected return date:
July 2020 		 Last updated:
19th May 2020
             

 
             
Ezetimibe/Simvastatin Clonmel 10mg/10mg 

PA0126/281/001		 Ezetimibe & Simvastatin  Manufacturing delay  Date of shortage:
6th January 2020

Expected return date:
21st July 2020 
 Last updated:
24th April 2020
Folinic Acid 10mg/ml Solution for Injection

(50mg/5mg presentation only)

PA0822/198/003 		 Folinic acid  Manufacturing delays  Date of shortage:
End of March 2020

Expected return date:
End of May 2020		 Last updated:
21st May 2020 
Folinic Acid 10mg/ml Solution for Injection

(100mg/10ml presentation only)

PA0822/198/003 		 Folinic acid  Manufacturing delays  Date of shortage:
5th July 2019

Expected return date:
July 2020		 Last updated:
10th February 2020
Fluzac 20mg Capsule

PA0711/110/001 		 Fluoxetine  Unexpected increase in demand  Date of shortage:
17th April 2020

Expected return date:
June 2020 		 Last updated:
8th May 2020 
Genotropin Miniquick 0.4mg Powder and Solvent for Solution for Injection

PA0822/128/004 		 Somatropin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
23rd April 2020

Expected return date:
End of June 2020		 Last updated:
28th April 2020 
Genotropin Miniquick 1.6mg Powder and Solvent for Solution for Injection

PA0822/128/010 		 Somatropin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid March 2020

Expected return date:
End of June 2020 		 Last updated:
28th April 2020 
Genotropin Miniquick 1.8mg Powder and Solvent for Solution for Injection

PA0822/128/011 
 Somatropin
 Manufacturing delays

(multiple countries affected) 
 Date of shortage:
10th February 2020

Expected return date:
End of June 2020 
 Last updated:
28th April 2020 
Genotropin Miniquick 2mg Powder and Solvent for Solution for Injection

PA0822/128/012 
 Somatropin
 Manufacturing delays

(multiple countries affected)  		 Date of shortage:
6th February 2020

Expected return date:
End of June 2020 
 Last updated:
28th April 2020
Gentamicin 40 mg/ml Injection, vials

PA0822/203/001
 Gentamicin
 Manufacturing delays

(multiple countries impacted)		 Date of shortage:
9th December 2019

Expected return date:
August 2020
 Last updated:
10th February 2020
Gerozac 20mg Capsule

PA0577/200/001 		 Fluoxetine  Manufacturing delays  Date of shortage:
Early December 2019

Expected return date:
Unknown at present 		 Last updated:
27th April 2020 
Gerozac 60mg Capsule

PA0577/071/001 		 Fluoxetine  Manufacturing delays  Date of shortage:
Early December 2020

Expected return date:
End of May 2020		 Last updated:
25th May 2020 
Gertac 150mg Film Coated Tablet

PA0577/023/001 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers 

AHDMP Guidance for Prescribers
Gertac 300mg Film Coated Tablet

PA0577/023/002 		 Ranitidine  Active substance impurities

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers 

AHDMP Guidance for Prescribers
HBVAXPRO 40mcg Suspension for Injection

EU/1/01/183/015 		 Hepatitis B  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
12th November 2019

Expected return date:
End of 2020 		 Last updated:
13th November 2019 
Hypnovel 10mg/5ml Solution for Injection

PA2239/007/002		 Midazolam  Unexpected increase in demand  Date of shortage:
2nd April 2020

Expected return date:
August 2020		 Last updated:
21st May 2020 
Hypovase 1mg Tablet

PA0822/195/002 		 Prazosin hydrochloride  Manufacturing delay 

(multiple countries affected)		 Date of shortage:
Mid June 2019

Expected return date:
Awaiting update		 Last updated:
20th May 2020
Imdur 60mg Prolonged Release Tablet

PA2129/001/001 		 Isosorbide mononitrate  Manufacturing delays

(multiple countries affected)		 Date of shortage:
Mid May 2020

Expected return date:
Early July 2020 		 Last updated:
19th May 2020 
Indivina 1mg/2.5mg Tablet

PA1327/005/001 		 Medroxyprogestrone & Estradiol  Manufacturing delays  Date of shortage:
February 2020

Expected return date:
May 2020 		 Last updated:
25th February 2020 
Indivina 2mg/5mg Tablet

PA1327/005/003 		 Medroxyprogestrone & Estradiol  Manufacturing delays  Date of shortage:
February 2020

Expected return date:
May 2020 		 Last updated:
25th February 2020 
Irprestan 150mg Film Coated Tablet

PA1380/021/002 		 Irprestan  Active substance impurity

(multiple countries affected) 		 Date of shortage:
February 2019

Expected return date:
June 2020		 Last updated:
22nd April 2019 
Isoptin 40mg Film Coated Tablet

PA2010/003/001 		 Verapamil  Manufacturing delays  Date of shortage:
End of April 2020

Expected return date:
End of June 2020		 Last updated:
25th May 2020 
Lanoxin 500mcg/2ml Solution for Injection

PA1691/001/001 		 Digoxin  Manufacturing delays  Date of shortage:
End of April 2020

Expected return date:
Mid August 2020 		 Last updated:
15th May 2020 
Lanoxin PG 62.5mcg Tablet 

PA1691/001/003
 Digoxin  Manufacturing delays  Date of shortage:
10th February 2020

Expected return date:
Mid July 2020
 Last updated:
15th May 2020 

HCP Letter
Lanoxin PG 50mcg/ml Elixir

PA1691/001/002 		 Digoxin  Manufcaturing delays  Date of shortage:
Mid May 2020

Expected return date:
Mid July 2020 		 Last updated:
15th May 2020 
Lanoxin PG 250mcg Tablet

PA1691/001/004 		 Digoxin  Manufacturing delays  Date of shortage:
17th March 2020

Expected return date:
End June 2020 		 Last updated:
15th May 2020 
Lercanidipine Mylan 10mg Tablet

PA0577/155/001		 Lercanidipine  Unexpected increase in demand  Date of shortage:
Early November 2019

Expected return date:
October 2020 		 Last updated:
21st January 2020 
Lercanidipine Mylan 20mg Tablet

PA0577/155/002 		 Lercanidipine  Unexpected increase in demand  Date of shortage:
Early November 2019

Expected return date:
October 2020 		 Last updated:
21st January 2020
Lipantil Supra 145mg Tablet

PA2010/015/003 		 Fenofibrate  Manufacturing delays  Date of shortage:
12th May 2020

Expected return date:
Early June 2020 		 Last updated:
15th May 2020 
Losamel 20mg Gastro-resistant tablets

PA0126/115/001		 Omeprazole Manufacturing delays Date of shortage: 
1st April 2020

Expected return date:
Unknown at present		 Last updated:
24th April 2020 
Losartan 50mg Tablet 

PA2315/059/002 		 Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
April 2021 		 Last updated:
22nd April 2020
Losartan 100mg Tablet

PA0749/090/004 		 Losartan  Unavailability of API

(multiple countries affected) 		 Date of shortage:
Early January 2020

Expected return date:
July 2020 		 Last updated:
23rd April 2020 
Losartan 100mg Tablet

PA2315/059/003 		 Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
April 2021		 Last updated:
22nd April 2020 
Losartan Hydrochlorothiazide 50mg/12.5mg Tablet

PA0749/026/001 		 Losartan & Hydrochlorothiazide  Unavailability of API

(multiple countries affected) 		 Date of shortage:
24th November 2019

Expected return date:
Q3 2020		 Last updated:
18th May 2020 
Lotanos 50mg Film Coated Tablet

PA0711/123/003 		 Losartan  Unexpected increase in demand  Date of shortage:
End of April 2020

Expected return date:
Early June 2020 		 Last updated:
7th May 2020 
Lotanos 100mg Film coated Tablet

PA0711/123/005 		 Losartan  Unexpected increase in demand  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present 		 Last updated:
31st March 2020 
Lustral 50mg Film-Coated Tablet

PA 0822/206/003 		 Sertraline hydrochloride Manufacturing delays Date of shortage:
End of April 2020

Expected return date:
End of May 2020		 Last updated:
28th April 2020 
Maxibar 98.45% w/w Powder for Oral Suspension

PA1826/002/001 		 Barium sulphate  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Awaiting update		 Last updated:
23rd April 2020 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
 Q1 2021		 Last updated:
29th April 2020
 
Mefac 500mg Capsule

PA0074/015/002 		 Mefanamic acid  Manufacturing delay  Date of shortage:
22nd April 2020

Expected return date:
Unknown at present 		 Last updated:
28th April 2020 
Melcam 7.5mg Tablet

PA0711/060/001 		 Meloxicam  Manufacturing delays  Date of shortage:
November 2019

Expected return date:
Unknown at present		 Last updated:
6th May 2020 
Melcam 15mg Tablet

PA0711/060/002 		 Meloxicam  Manufacturing delays  Date of shortage:
November 2019

Expected return date:
Early June 2020 		 Last updated:
6th May 2020
Minims Atropine Sulphate 1% Eye Drop Solution

PA0555/017/001 		 Atropine  Manufacturing delays  Date of shortage:
July 2019

Expected return date:
End of July 2020		 Last updated:
5th March 2020 
Minims Prednisolone 0.5% Eye Drop Solution

PA22698/016/001 		 Prednisolone  Unavailability of API

(multiple countries affected)		 Date of shortage:
End of May 2020

Expected return date:
July 2020 		 Last updated:
22nd May 2020 
Morphine Sulphate Injection BP 30mg/ml Solution for Injection

PA0361/004/005 		 Morphine Sulphate  Manufacturing delays  Date of shortage:
October 2018

Expected return date:
During 2020		 Last updated:
16th October 2019 
Muse 250mcg Urethral Stick

PA2010/028/002		 Alprostadil  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid March 2019
 
Expected return date:
Unknown at present		 Last updated:
25th May 2020
Nimbex 2mg/ml Solution for Infusion/Injection

PA1691/030/001		 Cistatracurium  Unexpected increase in demand

(multiple countries affected) 		 Date of shortage:
April 2020

Expected return date:
August 2020 		 Last updated:
13th May 2020 
Novolizer 200mg Budesonide Inhalation Powder

PA2010/032/001 		 Budesonide  Unexpected increase in demand  Date of shortage:
26th March 2020

Expected return date:
End of May 2020 		 Last updated:
1st April 2020 
Novolizer 100mcg Salbutamol Inhalation Powder

PA2010/033/001		 Salbutamol  Unexpected increase in demand  Date of shortage:
26th March 2020

Expected return date:
September 2020 		 Last updated:
1st April 2020 
Olmesartan Rowex 10mg Tablet

PA0711/1255/001 		 Olmesartan  Manufcatuirng delay  Date of shortage:
September 2019

Expected return date:
Awaiting update		 Last updated:
20th May 2020 
Omesar 10mg Tablet

PA0865/011/001 		 Olmesartan  Manufacturing delay  Date of shortage:
20th May 2020

Expected return date:
Early July 2020 		 Last updated:
19th May 2020 
Perdamel 0.5mg Film Coated Tablet

PA0126/169/002 		 Risperidone  Manufacturing delays  Date of shortage:
20th January 2020

Expected return date:
Mid July 2020 		 Last updated:
5th May 2020 
Piperacillin with Tazobactam 2.25g Powder for Solution for Injection

PA1339/001/001 		 Piperacillin sodium & Tazobactam sodium Manufacturing delays

(multiple countries affected)		 Date of shortage:
January 2018

Expected return date:
Unknown at present		 Last updated:
12th July 2019
Piperacillin with Tazobactam 4.5g Powder for Solution for Injection

PA1339/001/002 		 Piperacillin sodium & Tazobactam sodium Manufacturing delays

(multiple countries affected)		 Date of shortage:
January 2018

Expected return date:
Unknown at present		 Last updated:
12th July 2019
Pneumovax 23 Solution for Injection in Pre-filled Syringe

PA1286/055/002 		 Pneumococcal Polysaccharide Vacine  Unexpected increase in demand

(multiple countries affected)		 Date of shortage:
16th March 2020

Expected return date:
July 2020 		 Last updated:
23rd March 2020 
Propofol-Lipura 2% Emulsion for Injection or Infusion

PA0736/018/003 		 Propofol  Unexpected increase in demand  Date of shortage:
Mid May 2020

Expected return date:
End of May 2020 		 Last updated:
12th May 2020 
Propoven 2% Emulsion for Injection or Infusion

PA2059/017/003 		 Propofol  Unexpected increase in demand  Date of shortage:
End of March 2020

Expected return date:
End of May 2020 		 Last updated:
1st May 2020 
Prozamel 20mg Cpasule

PA0126/110/001 		 Fluoxetine  Manufcaturing delays
 		 Date of shortage:
End of March 2020

Expected return date:
Mid October 2020 		 Last updated:
24th March 2020 
Questran 4g Powder for Oral Suspension

PA2239/005/001 		 Colestyramine  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2019

Expected return date:
Q1 2021 		 Last updated:
22nd April 2020 
Rispone 6mg Film Coated Tablet

PA0711/106/005 		 Risperidone  Manufacturing delays  Date of shortage:
End of April 2020

Expected return date:
20th June 2020 		 Last updated:
8th May 2020 
Septrin Forte 160mg/800mg Tablet

PA1691/010/002 		 Sulfamethoxazole & Trimethoprim  Manufacturing delays  Date of shortage:
End of May 2020

Expected return date:
Mid June 2020 		 Last updated:
22nd May 2020 
Sertraline 50mg Film Coated Tablet

PA2315/101/003 		 Sertraline  Unavailability of API

(multiple ocuntries affected) 		 Date of shortage:
January 2020

Expected return date:
June 2020 		 Last updated:
22nd April 2020 
Sildenafil 50mg Film Coated Tablet

PA0126/199/002		 Sildenafil Unexpected increase in demand Date of shortage:
20th April 2020

Expected return date:
29th June 2020		 Last updated:
24th April 2020 
Sildenafil 100mg Film Coated Tablet

PA0126/199/003		 Sildenafil Unexpected increase in demand Date of shortage:
20th April 2020

Expected return date:
6th July 2020		  Last updated:
24th April 2020
Sofradex Ear/Eye Drops

PA0540/070/002 		 Framycetin, Gramicidin & Dexamethasone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid January 2020

Expected return date:
Unknown at present		 Last updated:
10th March 2020 
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
September 2020 		 Last updated:
3rd December 2019 
Sumatriptan 100mg Film Coated Tablet

PA2315/070/002
 		 Sumatriptan  Manufacturing delays  Date of shortage:
Early April 2020

Expected return date:
September 2020 		 Last updated:
17th April 2020 
Tamox 10mg Tablet

PA0711/022/001 		 Tamoxifen  Unexpected increase in demand Date of shortage:
18th October 2019
 
Expected return date:
Awaiting update		 Last updated:
12th May 2020
 
Prescriber Communication

Pharmacist Communication

Patients:
www.hse.ie/tamoxifen
 
Tefin 75mg Suppositories

PA1684/001/001 		 Ibuprofen  Manufacturing delays  Date of shortage:
August 2019

Expected return date:
June 2020		 Last updated:
8th April 2020
Tefin 150mg Suppositories

PA1684/001/002 		 Ibuprofen  Manufacturing delays  Date of shortage:
August 2019

Expected return date:
June 2020 		 Last updated:
8th April 2020 
Telmisartan 20mg film-coated tablet

PA0126/228/001		  Telmisartan Manufacturing delays  Date of shortage:
5th May 2020

Expected return date:
End June 2020 		 Last updated:
11th May 2020
Tipol 250mg Suppository

PA1684/002/003 		 Paracetamol  Manufactuirng delays  Date of shortage:
Early April 2020

Expected return date:
June 2020 		 Last updated:
24th April 2020 
Tipol 500mg Suppository

PA1684/002/004 		 Paracetamol  Manufacturing delays  Date of shortage:
Early April 2020

Expected return date:
June 2020 		 Last updated:
24th April 2020 
TOBI Podhaler 28mg Inhalation Powder; Capsule

EU/1/10/652/002 		 Tobramycin  Manufacturing delays  Date of shortage:
Mid May 2020

Expected return date:
Unknown at present 		 Last updated:
14th May 2020 
Tracurium 10mg/ml Solution for Injection or Infusion

PA1691/029/001 		 Atracurium  Manufacturing delays & Unexpected increase in demand  Date of shortage:
Mid May 2020

Expected return date:
Early July 2020 		 Last updated:
18th May 2020 
Trandate 100mg Film Coated Tablet

PA1638/006/002 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
August 2020		 Last updated:
6th April 2020 
Trandate 200mg Film Coated Tablet

PA1638/006/003 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
August 2020		 Last updated:
6th April 2020
Tranexamic acid 100mg/ml Solution for Injection

PA2315/178/001 		 Tranexamic acid  Manufacturing delays  Date of shortage:
Early July 2019

Expected return date:
Unknown at present 		 Last updated:
1st May 2020 
Ranitic 75mg Film Coated Tablet

PA0711/024/004 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
             
AHDMP Guidance for Prescribers
Ranitic 150mg Film Coated Tablet

PA0711/024/001 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers

AHDMP Guidance for Prescribers
 
Ranitic 300mg Film Coated Tablet

PA0711/024/002 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Ranitidine 150mg/10ml Oral Solution

PA22741/009/001 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Valsartan Actavis 40mg Film Coated Tablet 

PA1380/022/001		 Valsartan Active substance impurity

(multiple countries affected)
                        		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated: 
14th January 2020
Valsartan Actavis 80mg Film Coated Tablet

PA1380/022/002
     		 Valsartan Active substance impurity

(multiple countries affected)		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated:
14th January 2020
Valsartan Actavis 160mg Film Coated Tablet 

PA1380/022/003		 Valsartan Active substance impurity

(multiple countries affected)		 Date of shortage:
July 2018

Expected return date:
Awaiting update
 		 Last updated:
14th January 2020
Valsartan Teva 80mg Film Coated Tablet

PA0749/084/002 		 Valsartan Unexpected increase in demand

(multiple countries affected)		 Date of shortage:
July 2018

Expected return date:
Unknown at present		 Last updated:
6th April 2020
Valsartan Teva 160mg Film coated Tablet

PA0749/084/003 		 Valsartan  Unexpected increase in demand

(multiple countries affected)		 Date of shortage:
Awaiting update

Expected return date:
Unknown at present		 Last updated:
6th April 2020
Valsartan / Hydrochlorothiazide 160mg/ 25mg Film Coated Tablet

PA2315/181/003 		 Valsartan & Hydrochlorothiazide Active substance impurity

(multiple countries affected)		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated: 
21st February 2020
Valtan 40mg Film Coated Tablet 

PA0126/211/001 		 Valsartan Unexpected increase in demand

(multiple countries affected)		 Date of shortage:
24th October 2018

Expected return date:
Awaiting update		 Last updated:
18th November 2019
Valtan 80mg Film Coated Tablet

PA0126/211/002 		 Valsartan  Unexpected increase in demand

(multiple countries affected)		 Date of shortage:
26th September 2018
 
Expected return date:
Awaiting update
 Last updated:
18th November 2019
Valtan 160mg Film Coated Tablet

PA0126/211/003		 Valsartan  Unexpected increase in demand 

(multiple countries affected)		 Date of shortage:
24th October 2018

Expected return date:
Awaiting update		 Last updated:
18th November 2019
Vancomycin 500mg Powder for Concentrate for Solution for Infusion & Oral Solution

PA1122/008/001 		 Vancomycin  Manufacturing delays  Date of shortage:
Early April 2020

Expected return date:
Unknown at present 		 Last updated:
12th May 2020 
Vatan 40mg Film Coated Tablet

PA0711/183/001		 Valsartan  Active substance impurity

(multiple countries affected) 		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated:
18th November 2019
Vatan 80mg Film Coated Tablets

PA0711/183/002 		 Valsartan  Active Substance Impurity

(multiple countries affected) 		 Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated:
18th November 2019
Vatan 160mg Film Coated Tablets

PA0711/183/003 		 Valsartan Active Substance impurity

(multiple countries affected) 		  
Date of shortage:
July 2018

Expected return date:
Awaiting update		 Last updated:
18th November 2019
Vedixal 37.5mg Tablet

PA0711/161/002 		 Venlafaxine  Manufacturing delay  Date of shortage:
22nd April 2020

Expected return date:
5th June 2020		 Last updated:
28th April 2020 
Venlafaxine XL 37.5mg Prolonged Release Capsule

PA1347/036/001 		 Venlafaxine  Unexpected increase in demand  Date of shortage:
End of March 2020

Expected return date:
Mid July 2020 		 Last updated:
6th April 2020 
Venex XL 37.5mg Prolonged-Release Capsule

PA0126/285/001		  Venlafaxine Manufacturing delay Date of shortage:
07/05/2020

Expected return date:
Unknown at present		 Last updated:
7th May 2020 
Venex XL 150mg Prolonged-Release Capsule

PA0126/285/003 		 Venlafaxine  Manufacturing delay  Date of shortage:
Mid May 2020

Expected return date:
Unknown at present 		 Last updated:
15th May 2020 
Verap 120mg Prolonged Release Tablet

PA0711/016/004 		 Verapamil  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
End of 2020		 Last updated:
28th April 2020 
Warticon 0.15% w/w Cream 

PA1113/017/001 		 Podophyllotoxin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early October 2019

Expected return date:
Unknown at present 		 Last updated:
23rd April 2020
 
HCP Letter
Zacin 0.025% w/w Cream

PA0827/008/001 		 Capsaicin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid July 2019

Expected return date:
July 2020 		 Last updated:
21st May 2020 
Zantac 25mg/ml Solution for Injection/Infusion

PA1077/013/001 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Zantac 75mg Film Coated Tablet

PA1186/013/001 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers

AHDMP Guidance for Prescribers
 
Zantac 150mg Effervescent Tablet

PA1077/013/005 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Zantac 150mg Film Coated Tablet

PA1077/013/003 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Zantac 150mg/10ml Oral Solution

PA1077/013/002		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Zantac 300mg Film Coated Tablet

PA1077/013/004 		 Ranitidine  Active substance impurity

(multiple countries affected) 		 Date of shortage:
23rd September 2019

Expected return date:
Unknown at present 		 Last updated:
22nd October 2019

MMP Guidance for Prescribers
 
AHDMP Guidance for Prescribers
Zoely 2.5mg/1.5mg Film Coated Tablet 

EU/1/11/690/001		 Nomegestrol acetate & Esradiol  Unavailability of API

(multiple countries affected) 		 Date of shortage:
Early August 2019

Expected return date:
End of 2020		 Last updated:
27th January 2020
 
HCP Letter
Zolmitriptan 2.5mg Orodispersible Tablet

PA1380/035/003 		 Zolmitriptan  Manufacturing delays  Date of shortage:
Mid May 2020

Expected return date:
September 2020 		 Last updated:
11th May 2020 
Zomig 2.5mg Tablet

PA2242/004/001 		 Zolmitriptan  Manufacturing delays  Date of shortage:
Mid April 2020

Expected return date:
End of May 2020 		 Last updated:
20th May 2020 
Zorclone 7.5mg Film Coated Tablet

PA1986/080/001 		 Zopiclone  Manufacturing delays  Date of shortage:
Mid May 2020

Expected return date:
Early June 2020 		 Last updated:
21st May 2020 

Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL




Contact us:

Medicinal Product Shortages Unit
Health Products Regulatory Authority 
Kevin O’Malley House
Earlsfort Terrace,
Dublin 2
Tel: +353 1 676 4971
Fax: +353 1 676 7836
shortages@hpra.ie