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Medicinal Product Shortages

The HPRA is responsible for co-ordinating the management of shortages of human medicines on the Irish market. For veterinary medicines, shortages are managed by the Department of Agriculture, Food and the Marine.

The HPRA works with a variety of stakeholders including manufacturers, wholesale distributors, marketing authorisation holders, healthcare professionals, the Health Service Executive, patients and representative groups to respond to potential shortages and reduce the impact of shortages on patients.

The definition of a shortage is when the supply of a medicinal product is inadequate to meet the needs of the patient.

The HPRA, in collaboration with stakeholders, has published a framework for a multi-stakeholder approach to handling shortages of human medicinal products. The aim of the framework is to help prevent shortages from occurring and to reduce the impact of shortages on patients by co-ordinating the management of potential or actual shortages as they arise. You can see the shortages case study on Adrenaline auto-injectors (AAIs) as an example of how the framework operates in practice.

Information on reporting shortages for:

Current and resolved shortages

The HPRA publishes a list of shortages currently affecting the Irish market that have been notified to us and that may have a medium or high impact on patients. This list can be found below. More information on the impact level can be found in the framework for a multi-stakeholder approach to handling shortages of human medicinal products.

The HPRA maintains a consolidated list of resolved shortages for a period of six months. Details of shortages that have been resolved in the last six months can be found here.

Please use search function below to find relevant product or active ingredient

Product name	Active ingredient	Reason for shortage	Date of shortage	Additional information
Adrenaline (Epinephrine) 1:1,000 Solution for Injection PA0073/035/001	Adrenaline	Unexpected increase in demand	Date of shortage: Late November 2021 Expected return date: January 2022	Last updated: 29th November 2021 HCP Letter
Anapen 300mcg in 0.3ml Solution for Injection in a Pre Filled Syringe PA22580/001/002	Epinephrine	Unexpected increase in demand	Date of shortage: 28th October 2021 Expected return date: 13th December 2021	Last updated: 6th December 2021
Aripiprazole 15 mg tablets PA1986/019/003	Aripiprazole	Manufacturing delays	Date of shortage: 20th December 2021 Expected return date: 31st January 2022	Last updated: 24th November 2021
Axsain 0.075% w/w Cream PA1986/088/001	Capsacin	Manufacturing delays (multiple countries affected)	Date of shortage: Week commencing 15th November 2021 Expected return date: Week commencing 20th December 2021	Last updated: 18th November 2021
BCG-Medac Powder and Solvent for Suspension for Intravesical Use PA0623/004/001	Bacillus Calmette Guerin bacteria	Manufacturing delays (multiple countries affected)	Date of shortage: 1st October 2019 Expected return date: 2022	Last updated: 3rd February 2021
Beromun 1mg Powder for Solution for Infusion EU/1/99/097/001	Tasonermin	Manufacturing delays (multiple countries affected)	Date of shortage: December 2020 Expected return date: January 2022	Last updated: 2nd June 2021
Bonviva 3mg/ml Solution for Injection EU/1/03/265/5-6	Ibandronic Acid	Awaiting information	Date of shortage: Mid November 2021 Expected return date: Awaiting information	Last updated: 19th November 2021
Calcium Acetate 500mg Tablets PA0281/063/001	Calcium Acetate	API unavailability	Date of shortage: Week commencing 26th July 2021 Expected return date: Late December 2021	Last updated: 30th September 2021
Caverject 10mcg Powder and Solvent for Solution for Injection PA0822/115/002	Alprostadil	Manufacturing delays (multiple countries affected)	Date of shortage: 1st November 2021 Expected return date: 27th December 2021	Last updated: 3rd December 2021
Caverject 20mcg Powder and Solvent for Solution for Injection PA0822/115/003	Alprostadil	Manufacturing delays (multiple countries affected)	Date of shortage: 1st November 2021 Expected return date: 17th January 2022	Last updated: 3rd December 2021
Cefotaxime 1g Powder for solution for injection or infusion PA0281/223/002	Cefotaxime	Manufacturing delays	Date of shortage: 30th November 2021 Expected return date: Awaiting update	Last updated: 24th November 2021
Champix 0.5mg Film Coated Tablet EU/1/06/360/001	Varenicline	Quality issue (multiple countries affected)	Date of shortage: Week commencing 21st June 2021 Expected return date: Unknown at present	Last updated: 18th June 2021 HCP letter
Champix 1mg Film Coated Tablet EU/1/06/360/005	Varenicline	Quality issue (multiple countries affected)	Date of shortage: Week commencing 21st June Expected return date: Unknown at present	Last updated: 18th June 2021 HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet EU/1/06/360/003	Varenicline	Quality issue (multiple countries affected)	Date of shortage: Week commencing 21st June Expected return date: Unknown at present	Last updated: 18th June 2021 HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution PA2299/005/001	Chlorhexidine acetate & cetrimide	Unexpected increase in demand	Date of shortage: September 2021 Expected return date: Awaiting update	Last updated: 3rd December 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution PA0281/124/001	Chlorpromazine hydrochloride	Manufacturing delays	Date of shortage: End of February 2021 Expected return date: End January 2022	Last updated: 5th October 2021 HCP letter
Cholestagel 625mg Film Coated Tablets EU/1/03/268/003	Colesevelam	Unexpected increase in demand (multiple countries affected)	Date of shortage: 17th November 2021 Expected return date: January 2022	Last updated: 19th November 2021
Claforan Powder for Solution for Injection 1g PA0540/037/003	Cefotaxime	Unexpected increase in demand	Date of shortage: Week commencing 6th December 2021 Expected return date: 13th December 2021	Last updated: 6th December 2021
Clarithromycin 500mg Powder for Concentrate for Solution for Infusion PA1142/022/001	Clarithromycin	Manufacturing delays	Date of shortage: End of November 2021 Expected return date: March 2022	Last updated: 15th November 2021
Clexane 2,000 IU (20mg) /0.2 mL Solution for Injection in Pre-Filled Syringes PA0540/097/004	Enoxaparin sodium	Manufacturing delays (multiple countries affected)	Date of shortage: 10th December 2021 Expected return date: 29th December 2021	Last updated: 7th December 2021
Clexane 6,000 IU (60mg) /0.6 mL Solution for Injection in Pre-Filled Syringes PA0540/097/006	Enoxaparin sodium	Manufacturing delays (multiple countries affected)	Date of shortage: 27th December 2021 Expected return date: 10th January 2022	Last updated: 7th December 2021
Clexane 8,000 IU (80mg) /0.8 mL Solution for Injection in Pre-Filled Syringes PA0540/097/007	Enoxaparin sodium	Manufacturing delays (multiple countries affected	Date of shortage: 27th December Expected return date: 10th January 2022	Last updated: 7th December 2021
Clexane 10,000 IU (100mg)/1ml Solution for Injection in Pre-Filled Syringes PA0540/097/001	Enoxaparin sodium	Manufacturing delays (multiple countries affected)	Date of shortage: 20th December 2021 Expected return date: 10th January 2022	Last updated: 7th December 2021
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes PA0540/097/008	Enoxaparin sodium	API unavailability	Date of shortage: 22nd October 2021 Expected return date: January 2022	Last updated: November 19th 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion PA1457/001/001	Amoxicillin & clavulanic acid	Manufacturing delays	Date of shortage: 13th October 2021 Expected return date: Awaiting update	Last updated: 18th October 2021
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion PA1457/001/002	Amoxicillin & clavalunic acid	Unexpected increase in demand	Date of shortage: 5th February 2020 Expected return date: Awaiting update	Last updated: 19th October 2021
Combodart 0.5mg/ 0.4mg Hard Capsules PA1077/118/001	Dutasteride & tamsulosin	Manufacturing delays (multiple countries affected)	Date of shortage: 6th December 2021 Expected return date: 21st December 2021	Last updated: 7th December 2021
Cozaar 100mg Film Coated Tablets PA23198/002/003	Losartan	Manufacturing delays	Date of shortage: Week commencing 15th November 2021 Expected return date: Mid December 2021	Last updated: 8th November 2021
Cozaar Comp 100mg/25mg Film Coated Tablets PA23198/001/003	Losartan & Hydrochlorothiazide	Manufacturing delays	Date of shortage: Week commencing 15th November 2021 Expected return date: Mid December 2021	Last updated: 8th November 2021
Cozatan 50mg Film Coated Tablets PA0126/167/001	Losartan	Quality issue	Date of shortage: 20th October 2021 Expected return date: 18th January 2022	Last updated: 18th November 2021
Cozatan 100mg Film Coated Tablets PA0126/167/002	Losartan	Quality issue	Date of shortage: 20th October 2021 Expected return date: 18th January 2022	Last updated: 18th November 2021
Cozatan Comp 50mg/12.5mg Film Coated Tablets PA0126/184/001	Losartan potassium & hydrochlorothiazide	Quality issue	Date of shortage: 20th October 2021 Expected return date: 3rd January 2022	Last updated: 30th November 2021
Cozatan Comp 100mg/25mg Film Coated Tablets PA0126/184/002	Losartan potassium & hydrochlorothiazide	Quality issue	Date of shortage: 20th October 2021 Expected return date: 10th April 2022	Last updated: 30th November 2021
Depo-Provera 150mg/ml Suspension for Injection PA0822/124/001	Medroxyprogestrone acetate	Regulatory issue	Date of shortage: 15th November 2021 Expected return date: Mid-February 2022	Last updated: 16th November 2021
Deslor 5mg Film Coated Tablets PA0711/202/001	Desloratidine	Awaiting information	Date of shortage: 19th September 2021 Expected return date: Late December 2021	Last updated: October 2021
Desmopressin 100mcg/ml Nasal Drop Solution PA1009/001/001	Desmopressin	Manufacturing delays due to quality issue (multiple countries affected)	Date of shortage: Mid December 2020 Expected return date: 2022	Last updated: 11th December 2020
Desmospray Desmopressin Nasal Spray PA1009/005/001	Desmopressin	Quality issue (multiple countries affected)	Date of shortage: 22nd July 2020 Expected return date: 2022	Last updated: 11th December 2020
Detrunorm XL 30 mg Modified-Release Capsules PA1876/009/001	Propiverine hydrochloride	Manufacturing delay	Date of shortage: 1st December 2021 Expected return date: 7th January 2022	Last updated: 24th November 2021
Detrunorm XL 45 mg Modified-Release Capsules PA1876/009/002	Propiverine hydrochloride	Manufacturing delay	Date of shortage: 15th December 2021 Expected return date: 7th January 2022	Last updated: 24th November 2021
Diazemuls 5mg/ml Emulsion for Injection PA2315/098/001	Diazepam	Manufacturing delays	Date of shortage: Mid February 2020 Expected return date: Unknown at present	Last updated: 30th March 2021
Dioralyte Blackcurrant Powder for Oral Solution (20 pack) PA0540/098/001	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 17th September 2021 Expected return date: Awaiting update	Last updated: 15th November 2021
Dioralyte Citrus Powder for Oral Solution (20 pack) PA0540/098/002	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 17th September 2021 Expected return date: 8th December 2021	Last updated: 30th November 2021
Dioralyte Rebalance Citrus Powder for Oral Solution (6 pack) PA0540/194/002	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 17th September 2021 Expected return date: 8th December 2021	Last updated: 30th November 2021
Dioralyte Rebalance Natural Powder for Oral Solution (6 pack) PA0540/194/003	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 3rd November 2021 Expected return date: 8th December 2021	Last updated: 30th November 2021
Dopamine Hydrochloride 40mg/ml Sterile Concentrate PA0822/202/001	Dopamine	Unexpected increase in demand	Date of shortage: 6th December 2021 Expected return date: Unknown at present	Last updated: 8th December 2021
Emerade 150mcg Solution in a Pre-Filled Pen PA1696/009/001	Adrenaline	Quality issue (multiple countries affected)	Date of shortage: 30th September 2019 Expected return date: Unknown at present	Last updated: 18th December 2020 Alternatives are available
Emerade 300mcg Solution in a Pre-Filled Pen PA1696/009/002	Adrenaline	Quality issue (multiple countries affected)	Date of shortage: 30th September 2019 Expected return date: Unknown at present	Last updated: 18th December 2020 Alternatives are available
Emerade 500mcg Solution in a Pre-Filled Pen PA1696/009/003	Adrenaline	Quality issue (multiple countries affected)	Date of shortage: 30th September 2019 Expected return date: Unknown at present	Last updated: 18th December 2020 Alternatives are available
Emtricitabine/Tenofovir disoproxil Mylan 200mg/245mg Film Coated Tablets EU/1/16/1133/001-006	Emtricitabine & Tenofovir	Manufacturing delays	Date of shortage: Start of November 2021 Expected return date: Mid December 2021	Last updated: 30th November 2021
Epanutin Infatabs 50mg Chewable Tablets PA0822/011/005	Phenytoin	Manufacturing delays (multiple countries affected)	Date of shortage: Early November 2019 Expected return date: Awaiting update	Last updated: 16th November 2021 HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion PA1852/002/001	Esomeprazole	Unavailability of API	Date of shortage: Early October 2020 Expected return date: Awaiting update	Last updated: 30th November 2021
Ezetimibe Rowa 10mg Tablets PA0074/074/001	Ezetimibe	Manufacturing delays	Date of shortage: 4th November 2021 Expected return date: Late December 2021	Last updated: 26th November 2021
Ezetimibe 10mg tablets PA0577/198/001	Ezetimibe	Manufacturing delays	Date of shortage: Late August 2021 Expected return date: Awaiting update	Last updated: 15th November 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets PA0711/262/001	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: 22nd July 2021 Expected return date: Awaiting update	Last updated: 30th November 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets PA0711/262/003	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: 22nd July 2021 Expected return date: End December 2021	Last updated: 26th November 2021
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets PA1986/067/003	Ezetimibe & simvastatin	API unavailability (multiple countries impacted)	Date of shortage: 30th August 2021 Expected return date: Mid December 2021	Last updated: 28th October 2021
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets PA0126/281/002	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: Week commencing 20th September 2021 Expected return date: Awaiting update	Last updated: 18th November 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets PA0126/281/004	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: Week commencing 20th September 2021 Expected return date: 26th January 2022	Last updated: 9th November 2021
Ezetimibe/Simvastatin 10mg/80mg Tablets PA0577/180/003	Ezetimibe & Simvastatin	Unexpected increase in demand	Date of shortage: 11th November 2021 Expected return date: January 2022	Last updated: 16th November 2021
Exelon 9.5mg/day Transdermal patch EU/1/98/066/24	Rivastigmine	Quality issue (multiple countries affected)	Date of shortage: 21st October 2021 Expected return date: March 2022	Last updated: 16th November 2021
Flecainide 50mg Tablets PA1986/050/001	Flecainide	API unavailability	Date of shortage: Week commencing 15th November 2021 Expected return date: Week commencing 27th December 2021	Last updated: 8th November 2021
Fostepor Once Weekly 70mg Tablets PA0577/086/002	Alendronic acid	Manufacturing delay	Date of shortage: 15th December 2021 Expected return date: Awaiting update	Last updated: 1st December 2021
Gamanil 70mg Film Coated Tablets P1701/004/001	Lofepramine	Regulatory issue	Date of shortage: Late November 2021 Expected return date: January 2022	Last updated: 19th November 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension PA1142/014/001	Gentamicin & Hydrocortisone	Unavailability of API (multiple countries affected)	Date of shortage: 23rd August 2021 Expected return date: Early January 2022	Last updated: 30th November 2021
Gerax 250mcg Tablets PA1445/024/001	Alprazolam	Manufacturing delays	Date of shortage: Mid November 2021 Expected return date: February 2022	Last updated: 2rd December 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion PA0549/030/001	Hydromorphone	Manufacturing delays (multiple countries affected)	Date of shortage: Mid June 2020 Expected return date: February 2022	Last updated: 18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion PA0549/030/002	Hydromorphone	Manufacturing delays (multiple countries affected)	Date of shortage: Mid August 2020 Expected return date: February 2022	Last updated: 18th October 2021
Inegy 10mg/80mg Tablets PA23198/024/004	Ezetimibe & Simvastatin	Manufacturing delays	Date of shortage: 21st November 2021 Expected return date: 13th January 2022	Last updated: 10th November 2021
Instanyl 50mcg Nasal Spray EU/1/09/531/010-013	Fentanyl	Quality issue (multiple countries affected)	Date of shortage: 1st August 2021 Expected return date: February 2022	Last updated: 20th August 2021
Instanyl 100mcg Nasal Spray EU/1/09/531/014-017	Fentanyl	Quality issue (multiple countries affected)	Date of shortage: 2nd April 2021 Expected return date: February 2022	Last updated: 20th August 2021
Instanyl 200mcg Nasal Spray EU/1/09/531/018-021	Fentanyl	Quality issue (multiple countries affected)	Date of shortage: 2nd April 2021 Expected return date: February 2022	Last updated: 20th August 2021
Letrozole Mylan 2.5 mg Film Coated Tablets PA0577/116/001	Letrozole	Unexpected increase in demand	Date of shortage: Late November 2021 Expected return date: February 2022	Last updated: 15th November 2021
Letrozole 2.5mg Film Coated Tablets PA2315/109/001	Letrozole	Awaiting information	Date of shortage: Week commencing 25th October 2021 Expected return date: Awaiting update	Last updated: 30th November 2021
Letrozole 2.5mg Film Coated Tablets PA0126/198/001	Letrozole	Manufacturing delays	Date of shortage: 22nd October 2021 Expected return date: 22nd December 2021	Last updated: 18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets PA0749/085/001	Letrozole	API unavailability (multiple countries affected)	Date of shortage: Week commencing 9th August 2021 Expected return date: January 2021	Last updated: 5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet PA0711/051/002	Lisinopril & Hydrochlorothiazide	Manufacturing delays	Date of shortage: 8th September 2020 Expected return date: Awaiting update	Last updated: 30th November 2021
Losartan Potassium Pinewood 50mg Film Coated Tablets PA0281/154/002	Losartan	Quality issues	Date of shortage: 28th October 2021 Expected return date: Early December 2021	Last updated: 29th October 2021
Losartan 50mg Tablets PA2315/059/002	Losartan	Manufacturing delays	Date of shortage: 25th September 2019 Expected return date: Unknown at present	Last updated: 13th April 2021
Losartan Rowa 100mg Film Coated Tablets PA0074/082/003	Losartan	Quality issue (multiple countries affected)	Date of shortage: Week commencing 29th November 2021 Expected return date: Unknown at present	Last updated: 19th November
Losartan 100mg Tablet PA2315/059/003	Losartan	Manufacturing delays	Date of shortage: October 2019 Expected return date: Unknown at present	Last updated: 13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film Coated Tablets PA0749/026/001	Losartan & Hydrochlorothiazide	Quality issue	Date of shortage: Late October 2021 Expected return date: March 2022	Last updated: 22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets PA0749/026/002	Losartan & Hydrochlorothiazide	Quality issue	Date of shortage: Late October 2021 Expected return date: March 2022	Last updated: 22nd October 2021
Lycimor 300mg Hard Capsules PA1380/130/001	Lymecycline	Manufacturing delay (multiple countries affected)	Date of shortage: 16th December 2021 Expected return date: 17th January 2022	Last updated: 24th November 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection PA1691/025/002	Bupivacaine & adrenaline	Manufacturing delay (multiple countries affected)	Date of shortage: 1st July 2021 Expected return date: Unknown at present	Last updated: 24th September 2021
Mefac 250mg Capsule PA0074/015/001	Mefenamic acid	Manufacturing delays	Date of shortage: End of June 2019 Expected return date: Unknown at present	Last updated: 23rd April 2021
Metaraminol 10mg/ml Solution for Injection or Infusion PA22893/001/001	Metaraminol	Awaiting update	Date of shortage: Early April 2021 Expected return date: Awaiting update	Last updated: 30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution PA23081/008/001	Metformin	Regulatory Issue	Date of shortage: 13th August 2021 Expected return date: Unknown at present	Last updated: 10th August 2021
Minulet 75mcg/30mcg Coated Tablets PA0822/093/001	Ethinyloestradiol & Gestodene	Manufacturing delays	Date of shortage: 10th December 2021 Expected return date: 23rd December 2021	Last updated: 30th November 2021
Molaxole Powder for Oral Solution PA2010/025/001	Macrogol 3350, Sodium chloride, Potassium chloride, Sodium hydrogen carbonate	Regulatory issue	Date of shortage: 29th November 2021 Expected return date: Unknown at present	Last updated: 18th November 2021
Mydrilate 1.0% w/v Eye Drops PA22709/003/002	Cyclopentolate	Manufacturing delay	Date of shortage: Early September 2021 Expected return date: Awaiting update	Last updated: 26th October 2021
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion PA0073/111/002	Naloxone	Manufacturing delays	Date of shortage: 18th October 2021 Expected return date: Early January 2022	Last updated: 7th December 2021
Navelbine 30mg Soft Capsule PA0329/011/002	Vinorelbine	Manufacturing delays (multiple countries affected)	Date of shortage: 17th November 2021 Expected return date: January 2022	Last updated: 17th November 2021
Ondansetron 2mg/ml Solution for Injection (2ml presentation) PA1122/004/001	Ondansetron	Shipping delay	Date of shortage: Early December 2021 Expected return date: 17th December 2021	Last updated: 6th December 2021
Ondansetron 2 mg/ml Solution for Injection or Infusion PA0577/083/001	Ondansetron	Unexpected increase in demand	Date of shortage: Early November 2021 Expected return date: December 2021	Last updated: 1st December 2021
Oramox 125mg/5ml Powder for Oral Suspension PA0298/019/001	Amoxicillin	Unexpected increase in demand	Date of shortage: 22nd October 2021 Expected return date: Unknown at present	Last updated: 19th October 2021
Oramox 250mg/5ml Powder for Oral Suspension PA0298/019/002	Amoxicillin	Unexpected increase in demand	Date of shortage: 8th November 2021 Expected return date: Unknown at present	Last updated: 3rd November 2021
Orencia 125mg Solution for Injection in Pre Filled Pen EU/1/07/389/011	Abatacept	Manufacturing delays (multiple countries affected)	Date of shortage: 3rd November 2021 Expected return date: Awaiting update	Last updated: 19th November 2021
Oxycodone hydrochloride 50mg/ml Solution for Injection or Infusion PA0281/235/002	Oxycodone	Manufacturing delays	Date of shortage: 1st November 2021 Expected return date: Unknown at present	Last updated: 4th November 2021
Palexia 4mg/ml Oral Solution PA2242/012/010	Tapentadol hydrochloride	Quality issue (multiple countries affected)	Date of shortage: 15th February 2021 Expected return date: Unknown at present	Last updated: 22nd February 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w PA0278/017/002	Hydrocortisone & Lidocaine Hydrochloride	Manufacturing delays	Date of shortage: February 2021 Expected return date: January 2022	Last updated: 8th April 2021
Pinamox 125mg/5ml Powder for Oral Suspension PA0298/010/001	Amoxicillin	Manufacturing delays (multiple countries affected)	Date of shortage: Week commencing 15th November 2021 Expected return date: January 2022	Last updated: 16th November 2021
Qlaira Film Coated Tablets PA1410/058/001	Estradiol	API unavailability	Date of shortage: Mid November 2021 Expected return date: Q2 2022	Last updated: 7th October 2021 HCP letter
Questran 4g Powder for Oral Suspension PA2239/005/001	Colestyramine	Manufacturing delays (multiple countries affected)	Date of shortage: Mid June 2019 Expected return date: April 2022	Last updated: 7th December 2021
Relpax 40mg Film Coated Tablets PA23055/002/002	Eletriptan	Manufacturing delays	Date of shortage: 19th December 2021 Expected return date: 15th January 2022	Last updated: 8th December 2021
Rosuvastatin 5mg Film Coated Tablets PA2315/068/001	Rosuvastatin	Quality issue	Date of shortage: 27th August 2021 Expected return date: Q2 2022	Last updated: 30th August 2021
Rosuvastatin 10mg Film Coated Tablets PA2315/068/002	Rosuvastatin	Quality issue	Date of shortage: 27th August 2021 Expected return date: Q2 2022	Last updated: 30th August 2021
Rosuvastatin 20mg Film Coated Tablets PA2315/068/003	Rosuvastatin	Distribution issue	Date of shortage: 18th October 2021 Expected return date: Early January 2022	Last updated: 21st October 2021
Rosuvastatin 40mg Film Coated Tablets PA2315/068/004	Rosuvastatin	Distribution issue	Date of shortage: 18th October 2021 Expected return date: Early January 2022	Last updated: 21st October 2021
Rowalief 500mg Film Coated Tablets (24 pack only) PA0074/065/001	Paracetamol	Unexpected increase in demand	Date of shortage: Week commencing 8th November 2021 Expected return date: End December 2021	Last updated: 26th November 2021
Sevelamer Carbonate 800mg Film Coated Tablets PA0577/205/001	Sevelamer	Manufacturing delays	Date of shortage: Late October Expected return date: Awaiting update	Last updated: 17th November 2021
Skinoren 15% Gel PA1025/009/001	Azelaic acid	Unexpected increase in demand	Date of shortage: 18th November 2021 Expected return date: 22nd January 2022	Last updated: 12th November 2021
Solu-Cortef Powder for Solution for Injection or Infusion 100mg PA0822/137/001	Hydrocortisone	Manufacturing delay	Date of shortage: Late November 2021 Expected return date: 20th December 2021	Last updated: 3rd December 2021 HCP letter
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension PA22906/001/001	Zinc oxide & Dimethicone	Manufacturing delays	Date of shortage: October 2019 Expected return date: Mid-December 2021	Last updated: 22nd October 2021
Stamaril, Powder and Solvent for Suspension for Injection in Pre Filled syringe. Yellow fever vaccine (Live) PA2131/008/001	Yellow fever virus 17 d-204 strain	Unexpected increase in demand	Date of shortage: 18th November 2021 Expected return date: March 2022	Last updated: 19th November 2021
Stesolid Rectal Solution 5mg PA2315/137/001	Diazepam	Manufacturing delays	Date of shortage: Late August 2021 Expected return date: January 2022	Last updated: 12th November 2021
Stesolid Rectal Solution 10mg PA2315/137/002	Diazepam	Manufacturing delays	Date of shortage: Week commencing 19th July 2021. Expected return date: January 2022	Last updated: 12th November 2021
Strattera 10mg Capsules	Atomoxetine	Regulatory issue	Date of shortage: 15th November 2021 Expected return date: 17th December 2021	Last updated: 1st November 2021
Strattera 25mg Capsules	Atomoxetine	Regulatory issue	Date of shortage: 15th November 2021 Expected return date: 17th December 2021	Last updated: 1st November 2021
Strattera 40mg Capsules	Atomoxetine	Regulatory issue	Date of shortage: 15th November 2021 Expected return date: 17th December 2021	Last updated: 1st November 2021
Telfast 180mg Film Coated Tablets PA23180/003/003	Fexofenadine hydrochloride	Unexpected increase in demand	Date of shortage: Late September 2021 Expected return date: Awaiting update	Last updated: 17th November 2021
Telmisartan Rowa 40mg Tablets PA0074/078/002	Telmisartan	Unexpected increase in demand	Date of shortage: 7th September 2021 Expected return date: Awaiting update	Last updated: 30th November 2021
TPN – various B. Braun products	Various	Manufacturing delays	Date of shortage: 4th October 2021 Expected return date: Unknown at present	Last updated: 5th October 2021 HCP letter
Tracrium 10mg/ml, Solution for Injection or Infusion (25ml ampoule)	Atracurium	Unexpected increase in demand	Date of shortage: 10th December 2021 Expected return date: 11th February 2022	Last updated: 30th November 2021
Travocort 0.1 + 1% w/w Cream PA1025/012/001	Diflucortolone & Isoconazole	Unexpected increase in demand	Date of shortage: Early December 29021 Expected return date: January 2022	Last updated: 1st December 2021
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment PA22650/004/001	Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride	Regulatory issue	Date of shortage: Late September 2021 Expected return date: Late December 2021	Last updated: 15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets PA1688/011/001	Theophylline	Manufacturing delays	Date of shortage: Week commencing 11th October 2021 Expected return date: 13th December 2021	Last updated: 3rd December 2021
Valoid 50mg Tablets PA1142/001/002	Cyclizine	Manufacturing delays	Date of shortage: 1st November 2021 Expected return date: Unknown at present	Last updated: 18th October 2021
Visudyne 15mg Powder for Solution for Infusion EU/1/00/140/001	Verteporfin	Manufacturing delay	Date of shortage: May 2021 Expected return date: Week commencing 6th December 2021	Last updated: 8th December 2021 HCP letter
Voriconazole 200mg Powder for Solution for Infusion PA2059/020/001	Voriconazole	Unexpected increase in demand (multiple countries affected)	Date of shortage: Week commencing 29th November 2021 Expected return date: February 2022	Last updated: 29th November 2021
Zacin 0.025% w/w Cream PA1986/090/001	Capsaicin	Manufacturing delays (multiple countries affected)	Date of shortage: Week commencing 22nd November 2021 Expected return date: Week commencing 13th December 2021	Last updated: 17th November 2021
Zerbaxa 1g/0.5g Powder for Concentrate for Solution for Infusion EU/1/15/1032/001	Ceftolozone & Tazobactam	Quality issue (multiple countries affected)	Date of shortage: 18th December 2020 Expected return date: Unknown at present	Last updated: 4th March 2021
Xatger 10mg Prolonged Release Tablets PA0577/079/002	Alfuzosin	Manufacturing delays	Date of shortage: End November 2021 Expected return date: Mid December 2021	Last updated: 1st December 2021
Xomolix 2.5mg/ml Solution for Injection PA2288/003/002	Droperidol	Quality issue (multiple countries affected)	Date of shortage: 29th May 2021 Expected return date: Unknown at present	Last updated: 2nd July 2021
Xylocaine 10 mg/delivered dose Mucosal Spray PA1691/028/001	Lidocaine	Shipping delay	Date of shortage: 6th December 2021 Expected return date: January 2022	Last updated: 29th November 2021

Menveo (EU/1/10/614/003)

Meningococcal Group A, C, W135 and Y conjugate vaccine

PIL

Menveo (EU/1/10/614/003)

Meningococcal Group A, C, W135 and Y conjugate vaccine

PIL

Menveo (EU/1/10/614/003)

Meningococcal Group A, C, W135 and Y conjugate vaccine

PIL

Date of shortage:
2nd July 2021

Expected return date:
Unknown at present

Date of shortage:
18th October 2021

Expected return date:
Early January 2022

Product name	Active ingredient	Reason for shortage	Date of shortage	Additional information
Abstral 100mcg Sublingual Tablets PA2288/004/002	Fentanyl	Manufacturing delay (multiple countries affected)	Date of shortage: 3rd September 2021 Expected return date: Week commencing 1st October 2021	Last updated: 22nd October 2021
Abstral 200mcg Sublingual Tablets PA2288/004/003	Fentanyl	Manufacturing delays (multiple countries affected)	Date of shortage: 15th August 2021 Return date: Week commencing 25th October 2021	Last updated: 22nd October 2021
Abstral 300mcg Sublingual Tablets PA2288/004/004	Fentanyl	Manufacturing delays (multiple countries affected)	Date of shortage: 5th October 2021 Expected return date: Week commencing 25th October 2021	Last updated: 22nd October 2021
Abstral 400mcg Sublingual Tablets PA2288/004/005	Fentanyl	Manufacturing delays (multiple countries affected)	Date of shortage: 4th October 2021 Expected return date: Early December 2021	Last updated: 22nd October 2021
Abstral 600mcg Sublingual Tablets PA2288/004/006	Fentanyl	Manufacturing delay (multiple countries affected)	Date of shortage: 2nd September 2021 Expected return date: Week commencing 25th October 2021	Last updated: 22nd October 2021
Abstral 700mcg Sublingual Tablets PA2288/004/007	Fentanyl	Manufacturing delay (multiple countries affected)	Date of shortage: 2nd September 2021 Expected return date: Early December 2021	Last updated: 22nd October 2021
Adizem-XL 180mg Prolonged Release Capsules PA1688/001/005	Dilitazem	Manufacturing delays	Date of shortage: 1st October 2021 Expected return date: November 2021	Last updated: 27th September 2021
Amitriptyline 25mg Film Coated Tablets PA0126/041/001	Amitriptyline	API unavailability	Date of shortage: 2nd September 2021 Expected return date: Late October 2021	Last updated: 7th September 2021 HCP letter
Astilin 10mg Tablets PA23163/001/001	Amitriptyline	Awaiting update	Date of shortage: 27th August 2021 Expected return date: 29th October 2021	Last updated: 5th October 2021 HCP letter
Ativan 4mg/ml Solution for Injection PA0822/090/002	Lorazepam	Manufacturing delays (multiple countries affected)	Date of shortage: Early August 2020 Expected return date: Unknown at present	Last updated: 14th May 2021 HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use PA0623/004/001	Bacillus Calmette Guerin bacteria	Manufacturing delays (multiple countries affected)	Date of shortage: 1st October 2019 Expected return date: 2022	Last updated: 3rd February 2021
Bendroflumethiazide 2.5mg Tablets PA22749/021/001	Bendroflumethiazide	Regulatory issue	Date of shortage: 3rd September 2021 Expected return date: Awaiting update	Last updated: 1st October 2021
Beromun 1mg Powder for Solution for Infusion EU/1/99/097/001	Tasonermin	Manufacturing delays (multiple countries affected)	Date of shortage: December 2020 Expected return date: November 2021	Last updated: 1st June 2021
Calcium Acetate 500mg Tablets PA0281/063/001	Calcium Acetate	API unavailability	Date of shortage: Week commencing 26th July 2021 Expected return date: Late December 2021	Last updated: 30th September 2021
Canesten HC 1% w/w + 1% w/w Cream PA1410/040/002	Clotrimazole & Hydrocortisone	Manufacturing delays	Date of shortage: 30th September 2021 Expected return date: 5th November 2021	Last updated: 22nd September 2021
Catapres Tablets 100mcg PA2256/003/001	Clonidine	Manufacturing delays (multiple countries affected)	Date of shortage: 25th July 2021 Expected return date: 25th October 2021	Last updated: 21st June 2021
Champix 0.5mg Film Coated Tablet EU/1/06/360/001	Varenicline	Quality issue (multiple countries affected)	Date of shortage: Week commencing 21st June 2021 Expected return date: Unknown at present	Last updated: 18th June 2021 HCP letter
Champix 1mg Film Coated Tablet EU/1/06/360/005	Varenicline	Quality issue (multiple countries affected)	Date of shortage: Week commencing 21st June Expected return date: Unknown at present	Last updated: 18th June 2021 HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet EU/1/06/360/003	Varenicline	Quality issue (multiple countries affected)	Date of shortage: Week commencing 21st June Expected return date: Unknown at present	Last updated: 18th June 2021 HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution PA2299/005/001	Chlorhexidine acetate & cetrimide	Unexpected increase in demand	Date of shortage: September 2021 Expected return date: Mid November 2021	Last updated: 20th October 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution PA0281/124/001	Chlorpromazine hydrochloride	Manufacturing delays	Date of shortage: End of February 2021 Expected return date: End January 2022	Last updated: 5th October 2021 HCP letter
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes PA0540/097/008	Enoxaparin sodium	API unavailability	Date of shortage: 22nd October 2021 Expected return date: Unknown at present	Last updated: 13th October 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion PA1457/001/001	Amoxicillin & Clavulanic acid	Manufacturing delays	Date of shortage: 13th October 2021 Expected return date: Awaiting update	Last updated: 18th October 2021
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion PA1457/001/002	Amoxicillin & clavalunic acid	Unexpected increase in demand	Date of shortage: 5th February 2020 Expected return date: Awaiting update	Last updated: 19th October 2021
CoAprovel 300mg/12.5mg Tablets EU/1/98/086/004	Irbesartan & Hydrochlorothiazide	Shipping delay	Date of shortage: 5th November 2021 Expected return date: Late November 2021	Last updated: 22nd October 2021
Cyklokapron 100 mg/mL Solution for Injection/Infusion PA0822/117/001	Tranexamic acid	Manufacturing delays	Date of shortage: Week commencing 18th October 2021 Expected return date: Week commencing 15th November 2021	Last updated: 5th October 2021
Deslor 5mg Film Coated Tablets PA0711/202/001	Desloratidine	Awaiting information	Date of shortage: 19th September 2021 Expected return date: Late December 2021	Last updated: October 2021
Desmopressin 100mcg/ml Nasal Drop Solution PA1009/001/001	Desmopressin	Manufacturing delays due to quality issue (multiple countries affected)	Date of shortage: Mid December 2020 Expected return date: 2022	Last updated: 11th December 2020
Desmospray Desmopressin Nasal Spray PA1009/005/001	Desmopressin	Quality issue (multiple countries affected)	Date of shortage: 22nd July 2020 Expected return date: 2022	Last updated: 11th December 2020
Diazemuls 5mg/ml Emulsion for Injection PA2315/098/001	Diazepam	Manufacturing delays	Date of shortage: Mid February 2020 Expected return date: Unknown at present	Last updated: 30th March 2021
Dioralyte Blackcurrant Powder for Oral Solution (20 pack) PA0540/098/001	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 17th September 2021 Expected return date: 1st November 2021	Last updated: 30th September 2021
Dioralyte Citrus Powder for Oral Solution (20 pack) PA0540/098/002	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 17th September 2021 Expected return date: 1st November 2021	Last updated: 30th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution (6 pack) PA0540/194/002	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 17th September 2021 Expected return date: 1st November 2021	Last updated: 30th September 2021
Doxatan 4mg Tablets PA0126/202/003	Doxazosin	Manufacturing delay	Date of shortage: 4th October 2021 Expected return date: Week commencing 1st November 2021	Last updated: 20th October 2021
Emerade 150mcg Solution in a Pre-Filled Pen PA1696/009/001	Adrenaline	Quality issue (multiple countries affected)	Date of shortage: 30th September 2019 Expected return date: Unknown at present	Last updated: 18th December 2020 Alternatives are available
Emerade 300mcg Solution in a Pre-Filled Pen PA1696/009/002	Adrenaline	Quality issue (multiple countries affected)	Date of shortage: 30th September 2019 Expected return date: Unknown at present	Last updated: 18th December 2020 Alternatives are available
Emerade 500mcg Solution in a Pre-Filled Pen PA1696/009/003	Adrenaline	Quality issue (multiple countries affected)	Date of shortage: 30th September 2019 Expected return date: Unknown at present	Last updated: 18th December 2020 Alternatives are available
Epanutin Infatabs 50mg Chewable Tablets PA0822/011/005	Phenytoin	Manufacturing delays (multiple countries affected)	Date of shortage: Early November 2019 Expected return date: Unknown at present	Last updated: 4th June 2020 HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion PA1852/002/001	Esomeprazole	Unavailability of API	Date of shortage: Early October 2020 Expected return date: Late November 2021	Last updated: 12th October 2021
Ezetimibe Rowa 10mg Tablets PA0074/074/001	Ezetimibe	Awaiting information	Date of shortage: 19th October 2021 Expected return date: Late November 2021	Last updated: 21st October 2021
Ezetimibe Teva 10mg tablets PA1986/012/001	Ezetimibe	Quality Issue	Date of shortage: 18th October 2021 Expected return date: 13th December 2021	Last updated: 4th October 2021
Ezetimibe 10mg tablets PA0577/198/001	Ezetimibe	Manufacturing delays	Date of shortage: Late August 2021 Expected return date: Early November 2021	Last updated: 4th October 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets PA0711/262/001	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: 22nd July 2021 Expected return date: October 2021	Last updated: 20th September 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets PA0711/262/003	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: 22nd July 2021 Expected return date: End November 2021	Last updated: 20th October 2021
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets PA1986/067/003	Ezetimibe & simvastatin	API unavailability (multiple countries impacted)	Date of shortage: 30th August 2021 Expected return date: Awaiting update	Last updated: 20th October 2021
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets PA0126/281/002	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: Week commencing 20th September 2021 Expected return date: Unknown at present	Last updated: 20th September 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets PA0126/281/004	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: Week commencing 20th September 2021 Expected return date: Unknown at present	Last updated: 20th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection PA0822/198/002	Folinic Acid	Unexpected increase in demand	Date of shortage: Week commencing 27th September 2021 Expected return date: Awaiting update	Last updated: 18th October 2021
Fomicyt 40mg/ml Powder for Solution for Infusion PA1972/001/001	Fosfomycin sodium	Regulatory issue	Date of Shortage: October 2021 Expected return date: Unknown at present	Last updated: 12th October 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension PA1142/014/001	Gentamicin & Hydrocortisone	Unavailability of API (multiple countries affected)	Date of shortage: 23rd August 2021 Expected return date: Late November 2021	Last updated: 9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion PA0549/030/001	Hydromorphone	Manufacturing delays (multiple countries affected)	Date of shortage: Mid June 2020 Expected return date: February 2022	Last updated: 18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion PA0549/030/002	Hydromorphone	Manufacturing delays (multiple countries affected)	Date of shortage: Mid August 2020 Expected return date: February 2022	Last updated: 18th October 2021
Imodium Plus 2mg/125mg Tablets PA0330/050/001	Loperamide & simeticone	Manufacturing delay	Date of shortage: 11th October 2021 Expected return date: Week commencing 22nd November 2021	Last updated: 20th October 2021
Innohep 10,000 IU/ml Solution for Injection PA0046/060/002	Tinzaparin sodium	Unexpected increase in demand (multiple countries affected)	Date of shortage: 20th September 2021 Expected return date: Mid-November 2021	Last updated: 23rd September 2021
Instanyl 50mcg Nasal Spray EU/1/09/531/010-013	Fentanyl	Quality issue (multiple countries affected)	Date of shortage: 1st August 2021 Expected return date: February 2022	Last updated: 20th August 2021
Instanyl 100mcg Nasal Spray EU/1/09/531/014-017	Fentanyl	Quality issue (multiple countries affected)	Date of shortage: 2nd April 2021 Expected return date: February 2022	Last updated: 20th August 2021
Instanyl 200mcg Nasal Spray EU/1/09/531/018-021	Fentanyl	Quality issue (multiple countries affected)	Date of shortage: 2nd April 2021 Expected return date: February 2022	Last updated: 20th August 2021
Invokana 300mg Film Coated Tablets EU/1/13/884/005-008	Canagliflozin	Unexpected increase in demand	Date of shortage: 18th October 2021 Expected return date: Early November 2021	Last updated: 12th October 2021
Letrozole 2.5mg Film Coated Tablets PA2315/109/001	Letrozole	Awaiting information	Date of shortage: Week commencing 25th October 2021 Expected return date: End November 2021	Last updated: 18th October 2021
Letrozole 2.5mg Film Coated Tablets PA0126/198/001	Letrozole	Manufacturing delays	Date of shortage: 22nd October 2021 Expected return date: 22nd December 2021	Last updated: 18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets PA0749/085/001	Letrozole	API unavailability (multiple countries affected)	Date of shortage: Week commencing 9th August 2021 Expected return date: January 2021	Last updated: 5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet PA0711/051/002	Lisinopril & Hydrochlorothiazide	Manufacturing delays	Date of shortage: 8th September 2020 Expected return date: Week commencing 1st November 2021	Last updated: 20th October 2021
Losartan 50mg Tablet PA2315/059/002	Losartan	Manufacturing delays	Date of shortage: 25th September 2019 Expected return date: Unknown at present	Last updated: 13th April 2021
Losartan 100mg Tablet PA2315/059/003	Losartan	Manufacturing delays	Date of shortage: October 2019 Expected return date: Unknown at present	Last updated: 13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film-Coated Tablets PA0749/026/001	Losartan & Hydrochlorothiazide	Quality issue	Date of shortage: Late October 2021 Expected return date: March 2022	Last updated: 22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets PA0749/026/002	Losartan & Hydrochlorothiazide	Quality issue	Date of shortage: Late October 2021 Expected return date: March 2022	Last updated: 22nd October 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection PA1691/025/002	Bupivacaine & adrenaline	Manufacturing delay (multiple countries affected)	Date of shortage: 1st July 2021 Expected return date: Unknown at present	Last updated: 24th September 2021
Mefac 250mg Capsule PA0074/015/001	Mefenamic acid	Manufacturing delays	Date of shortage: End of June 2019 Expected return date: Unknown at present	Last updated: 23rd April 2021
Metaraminol 10mg/ml Solution for Injection or Infusion PA22893/001/001	Metaraminol	Awaiting update	Date of shortage: Early April 2021 Expected return date: Awaiting update	Last updated: 30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution PA23081/008/001	Metformin	Regulatory Issue	Date of shortage: 13th August 2021 Expected return date: Unknown at present	Last updated: 10th August 2021
Mydrilate 1.0% w/v Eye Drops PA22709/003/002	Cyclopentolate	Manufacturing delay	Date of shortage: Early September 2021 Expected return date: Mid-October 2021	Last updated: 27th September 2021
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion PA0073/111/002	Naloxone	Manufacturing delay	Date of shortage: 18th October 2021 Expected return date: 3rd December 2021	Last updated: 19th October 2021
Nanocis 0.24mg Kit for Radiopharmaceutical Preparation PA0677/006/001	Rhenium sulphide	Awaiting information	Date of shortage: Week commencing 20th September 2021 Expected return date: Week commencing 8th November 2021	Last updated: 1st October 2021
Odrik 2mg Hard Capsule PA2010/005/003	Trandolapril	Manufacturing delays	Date of shortage: 5th October 2021 Expected return date: Late October 2021	Last updated: 28th September 2021
Oramox 125mg/5ml Powder for Oral Suspension PA0298/019/001	Amoxicillin	Unexpected increase in demand	Date of shortage: 22nd October 2021 Expected return date: Unknown at present	Last updated: 19th October 2021
OxyContin 5mg Prolonged Release Tablets PA1688/005/001	Oxycodone	Manufacturing delays	Date of shortage: 18th October 2021 Expected return date: Early November 2021	Last updated: 12th October 2021
OxyNorm Dispersa 5mg Orodispersible Tablets PA1688/006/007	Oxycodone	Unexpected increase in demand	Date of shortage: 5th October 2021 Expected return date: 4th November 2021	Last updated: 18th October 2021
OxyNorm Dispersa 10mg Orodispersible Tablets PA1688/006/008	Oxycodone	Manufacturing delays	Date of shortage: 18th October 2021 Expected return date: Unknown at present	Last updated: 12th October 2021
OxyNorm Dispersa 20mg Orodispersible Tablets PA1688/006/009	Oxycodone	Manufacturing delays	Date of shortage: 26th October 2021 Expected return date: February 2022	Last updated: 20th October 2021
Palexia 4mg/ml Oral Solution PA2242/012/010	Tapentadol hydrochloride	Quality issue (multiple countries affected)	Date of shortage: 15th February 2021 Expected return date: Unknown at present	Last updated: 22nd February 2021
Paralief 500mg Tablets 24 pack only PA0126/020/001	Paracetamol	API unavailability	Date of shortage: Week commencing 23rd August 2021 Expected return date: 27th October 2021	Last updated: 28th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w PA0278/017/002	Hydrocortisone & Lidocaine Hydrochloride	Manufacturing delays	Date of shortage: February 2021 Expected return date: January 2022	Last updated: 8th April 2021
Qlaira Film Coated Tablets PA1410/058/001	Estradiol	API unavailability	Date of shortage: Mid November 2021 Expected return date: Q2 2022	Last updated: 7th October 2021 HCP letter
Questran 4g Powder for Oral Suspension PA2239/005/001	Colestyramine	Manufacturing delays (multiple countries affected)	Date of shortage: Mid June 2019 Expected return date: January 2022	Last updated: 30th March 2021
Rifater 50mg/300mg/120mg Tablets PA0822/143/002	Isoniazid & Pyrazinamide & Rifampicin	Quality issue (multiple countries impacted)	Date of shortage: 23rd July 2021 Expected return date: 26th October 2021	Last updated: 18th October 2021 AMRIC guidance V3
Rosuvastatin 5mg Film Coated Tablets PA2315/068/001	Rosuvastatin	Quality issue	Date of shortage: 27th August 2021 Expected return date: Q2 2022	Last updated: 30th August 2021
Rosuvastatin 10mg Film Coated Tablets PA2315/068/002	Rosuvastatin	Quality issue	Date of shortage: 27th August 2021 Expected return date: Q2 2022	Last updated: 30th August 2021
Rosuvastatin 20mg Film Coated Tablets PA2315/068/003	Rosuvastatin	Distribution issue	Date of shortage: 18th October 2021 Expected return date: Early January 2022	Last updated: 21st October 2021
Rosuvastatin 40mg Film Coated Tablets PA2315/068/004	Rosuvastatin	Distribution issue	Date of shortage: 18th October 2021 Expected return date: Early January 2022	Last updated: 21st October 2021
Sevelamer Carbonate 800mg Film Coated Tablets PA0577/205/001	Sevelamer	Manufacturing delays	Date of shortage: Late October Expected return date: Unknown at present	Last updated: 22nd October 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension PA22906/001/001	Zinc oxide & Dimethicone	Manufacturing delays	Date of shortage: October 2019 Expected return date: Mid-December 2021	Last updated: 22nd October 2021
Stesolid Rectal Solution 5mg PA2315/137/001	Diazepam	Manufacturing delays	Date of shortage: Late August 2021 Expected return date: November 2021	Last updated: 12th August 2021
Stesolid Rectal Solution 10mg PA2315/137/002	Diazepam	Manufacturing delays	Date of shortage: Week commencing 19th July 2021. Expected return date: November 2021	Last updated: 21st July 2021
Targin 20mg/10mg Prolonged Release Tablets PA1688/010/001	Oxycodone & Naloxone	Shipping delays	Date of shortage: 27th September 2021 Expected return date: 28th October 2021	Last updated: 22nd October 2021
Telmisartan Rowa 40mg Tablets PA0074/078/002	Telmisartan	Unexpected increase in demand	Date of shortage: 7th September 2021 Expected return date: Late November 2021	Last updated: 20th October 2021
Tevanate Once Weekly 70mg Tablets PA0749/016/001	Alendronic acid	API unavailability	Date of shortage: 6th September 2021 Expected return date: Late November 2021	Last updated: 23rd August 2021
Tracrium 10 mg/ml, Solution for injection or infusion (25ml ampoule) PA1691/029/002	Atracurium	Unexpected increase in demand	Date of shortage: 24th September 2021 Expected return date: 20th November 2021	Last updated: 24th September 2021
Trandate 200mg Film Coated Tablet PA1638/006/003	Labetalol hydrochloride	Manufacturing delays (multiple countries affected)	Date of shortage: July 2019 Expected return date: End October 2021	Last updated: 11th October 2021
TPN – various B. Braun products	Various	Manufacturing delays	Date of shortage: 4th October 2021 Expected return date: Unknown at present	Last updated: 5th October 2021 HCP letter
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment PA22650/004/001	Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride	Regulatory issue	Date of shortage: Late September 2021 Expected return date: Late December 2021	Last updated: 15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets PA1688/011/001

Product name	Active ingredient	Reason for shortage	Date of shortage	Additional information
Abstral 100mcg Sublingual Tablets PA2288/004/002	Fentanyl	Manufacturing delay (multiple countries affected)	Date of shortage: 3rd September 2021 Expected return date: Week commencing 1st October 2021	Last updated: 22nd October 2021
Abstral 200mcg Sublingual Tablets PA2288/004/003	Fentanyl	Manufacturing delays (multiple countries affected)	Date of shortage: 15th August 2021 Return date: Week commencing 25th October 2021	Last updated: 22nd October 2021
Abstral 300mcg Sublingual Tablets PA2288/004/004	Fentanyl	Manufacturing delays (multiple countries affected)	Date of shortage: 5th October 2021 Expected return date: Week commencing 25th October 2021	Last updated: 22nd October 2021
Abstral 400mcg Sublingual Tablets PA2288/004/005	Fentanyl	Manufacturing delays (multiple countries affected)	Date of shortage: 4th October 2021 Expected return date: Early December 2021	Last updated: 22nd October 2021
Abstral 600mcg Sublingual Tablets PA2288/004/006	Fentanyl	Manufacturing delay (multiple countries affected)	Date of shortage: 2nd September 2021 Expected return date: Week commencing 25th October 2021	Last updated: 22nd October 2021
Abstral 700mcg Sublingual Tablets PA2288/004/007	Fentanyl	Manufacturing delay (multiple countries affected)	Date of shortage: 2nd September 2021 Expected return date: Early December 2021	Last updated: 22nd October 2021
Adizem-XL 180mg Prolonged Release Capsules PA1688/001/005	Dilitazem	Manufacturing delays	Date of shortage: 1st October 2021 Expected return date: November 2021	Last updated: 27th September 2021
Amitriptyline 25mg Film Coated Tablets PA0126/041/001	Amitriptyline	API unavailability	Date of shortage: 2nd September 2021 Expected return date: Late October 2021	Last updated: 7th September 2021 HCP letter
Astilin 10mg Tablets PA23163/001/001	Amitriptyline	Awaiting update	Date of shortage: 27th August 2021 Expected return date: 29th October 2021	Last updated: 5th October 2021 HCP letter
Ativan 4mg/ml Solution for Injection PA0822/090/002	Lorazepam	Manufacturing delays (multiple countries affected)	Date of shortage: Early August 2020 Expected return date: Unknown at present	Last updated: 14th May 2021 HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use PA0623/004/001	Bacillus Calmette Guerin bacteria	Manufacturing delays (multiple countries affected)	Date of shortage: 1st October 2019 Expected return date: 2022	Last updated: 3rd February 2021
Bendroflumethiazide 2.5mg Tablets PA22749/021/001	Bendroflumethiazide	Regulatory issue	Date of shortage: 3rd September 2021 Expected return date: Awaiting update	Last updated: 1st October 2021
Beromun 1mg Powder for Solution for Infusion EU/1/99/097/001	Tasonermin	Manufacturing delays (multiple countries affected)	Date of shortage: December 2020 Expected return date: November 2021	Last updated: 1st June 2021
Calcium Acetate 500mg Tablets PA0281/063/001	Calcium Acetate	API unavailability	Date of shortage: Week commencing 26th July 2021 Expected return date: Late December 2021	Last updated: 30th September 2021
Canesten HC 1% w/w + 1% w/w Cream PA1410/040/002	Clotrimazole & Hydrocortisone	Manufacturing delays	Date of shortage: 30th September 2021 Expected return date: 5th November 2021	Last updated: 22nd September 2021
Catapres Tablets 100mcg PA2256/003/001	Clonidine	Manufacturing delays (multiple countries affected)	Date of shortage: 25th July 2021 Expected return date: 25th October 2021	Last updated: 21st June 2021
Champix 0.5mg Film Coated Tablet EU/1/06/360/001	Varenicline	Quality issue (multiple countries affected)	Date of shortage: Week commencing 21st June 2021 Expected return date: Unknown at present	Last updated: 18th June 2021 HCP letter
Champix 1mg Film Coated Tablet EU/1/06/360/005	Varenicline	Quality issue (multiple countries affected)	Date of shortage: Week commencing 21st June Expected return date: Unknown at present	Last updated: 18th June 2021 HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet EU/1/06/360/003	Varenicline	Quality issue (multiple countries affected)	Date of shortage: Week commencing 21st June Expected return date: Unknown at present	Last updated: 18th June 2021 HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution PA2299/005/001	Chlorhexidine acetate & cetrimide	Unexpected increase in demand	Date of shortage: September 2021 Expected return date: Mid November 2021	Last updated: 20th October 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution PA0281/124/001	Chlorpromazine hydrochloride	Manufacturing delays	Date of shortage: End of February 2021 Expected return date: End January 2022	Last updated: 5th October 2021 HCP letter
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes PA0540/097/008	Enoxaparin sodium	API unavailability	Date of shortage: 22nd October 2021 Expected return date: Unknown at present	Last updated: 13th October 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion PA1457/001/001	Amoxicillin & Clavulanic acid	Manufacturing delays	Date of shortage: 13th October 2021 Expected return date: Awaiting update	Last updated: 18th October 2021
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion PA1457/001/002	Amoxicillin & clavalunic acid	Unexpected increase in demand	Date of shortage: 5th February 2020 Expected return date: Awaiting update	Last updated: 19th October 2021
CoAprovel 300mg/12.5mg Tablets EU/1/98/086/004	Irbesartan & Hydrochlorothiazide	Shipping delay	Date of shortage: 5th November 2021 Expected return date: Late November 2021	Last updated: 22nd October 2021
Cyklokapron 100 mg/mL Solution for Injection/Infusion PA0822/117/001	Tranexamic acid	Manufacturing delays	Date of shortage: Week commencing 18th October 2021 Expected return date: Week commencing 15th November 2021	Last updated: 5th October 2021
Deslor 5mg Film Coated Tablets PA0711/202/001	Desloratidine	Awaiting information	Date of shortage: 19th September 2021 Expected return date: Late December 2021	Last updated: October 2021
Desmopressin 100mcg/ml Nasal Drop Solution PA1009/001/001	Desmopressin	Manufacturing delays due to quality issue (multiple countries affected)	Date of shortage: Mid December 2020 Expected return date: 2022	Last updated: 11th December 2020
Desmospray Desmopressin Nasal Spray PA1009/005/001	Desmopressin	Quality issue (multiple countries affected)	Date of shortage: 22nd July 2020 Expected return date: 2022	Last updated: 11th December 2020
Diazemuls 5mg/ml Emulsion for Injection PA2315/098/001	Diazepam	Manufacturing delays	Date of shortage: Mid February 2020 Expected return date: Unknown at present	Last updated: 30th March 2021
Dioralyte Blackcurrant Powder for Oral Solution (20 pack) PA0540/098/001	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 17th September 2021 Expected return date: 1st November 2021	Last updated: 30th September 2021
Dioralyte Citrus Powder for Oral Solution (20 pack) PA0540/098/002	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 17th September 2021 Expected return date: 1st November 2021	Last updated: 30th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution (6 pack) PA0540/194/002	Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate	Unexpected increase in demand	Date of shortage: 17th September 2021 Expected return date: 1st November 2021	Last updated: 30th September 2021
Doxatan 4mg Tablets PA0126/202/003	Doxazosin	Manufacturing delay	Date of shortage: 4th October 2021 Expected return date: Week commencing 1st November 2021	Last updated: 20th October 2021
Emerade 150mcg Solution in a Pre-Filled Pen PA1696/009/001	Adrenaline	Quality issue (multiple countries affected)	Date of shortage: 30th September 2019 Expected return date: Unknown at present	Last updated: 18th December 2020 Alternatives are available
Emerade 300mcg Solution in a Pre-Filled Pen PA1696/009/002	Adrenaline	Quality issue (multiple countries affected)	Date of shortage: 30th September 2019 Expected return date: Unknown at present	Last updated: 18th December 2020 Alternatives are available
Emerade 500mcg Solution in a Pre-Filled Pen PA1696/009/003	Adrenaline	Quality issue (multiple countries affected)	Date of shortage: 30th September 2019 Expected return date: Unknown at present	Last updated: 18th December 2020 Alternatives are available
Epanutin Infatabs 50mg Chewable Tablets PA0822/011/005	Phenytoin	Manufacturing delays (multiple countries affected)	Date of shortage: Early November 2019 Expected return date: Unknown at present	Last updated: 4th June 2020 HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion PA1852/002/001	Esomeprazole	Unavailability of API	Date of shortage: Early October 2020 Expected return date: Late November 2021	Last updated: 12th October 2021
Ezetimibe Rowa 10mg Tablets PA0074/074/001	Ezetimibe	Awaiting information	Date of shortage: 19th October 2021 Expected return date: Late November 2021	Last updated: 21st October 2021
Ezetimibe Teva 10mg tablets PA1986/012/001	Ezetimibe	Quality Issue	Date of shortage: 18th October 2021 Expected return date: 13th December 2021	Last updated: 4th October 2021
Ezetimibe 10mg tablets PA0577/198/001	Ezetimibe	Manufacturing delays	Date of shortage: Late August 2021 Expected return date: Early November 2021	Last updated: 4th October 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets PA0711/262/001	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: 22nd July 2021 Expected return date: October 2021	Last updated: 20th September 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets PA0711/262/003	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: 22nd July 2021 Expected return date: End November 2021	Last updated: 20th October 2021
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets PA1986/067/003	Ezetimibe & simvastatin	API unavailability (multiple countries impacted)	Date of shortage: 30th August 2021 Expected return date: Awaiting update	Last updated: 20th October 2021
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets PA0126/281/002	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: Week commencing 20th September 2021 Expected return date: Unknown at present	Last updated: 20th September 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets PA0126/281/004	Ezetimibe & simvastatin	Manufacturing delays	Date of shortage: Week commencing 20th September 2021 Expected return date: Unknown at present	Last updated: 20th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection PA0822/198/002	Folinic Acid	Unexpected increase in demand	Date of shortage: Week commencing 27th September 2021 Expected return date: Awaiting update	Last updated: 18th October 2021
Fomicyt 40mg/ml Powder for Solution for Infusion PA1972/001/001	Fosfomycin sodium	Regulatory issue	Date of Shortage: October 2021 Expected return date: Unknown at present	Last updated: 12th October 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension PA1142/014/001	Gentamicin & Hydrocortisone	Unavailability of API (multiple countries affected)	Date of shortage: 23rd August 2021 Expected return date: Late November 2021	Last updated: 9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion PA0549/030/001	Hydromorphone	Manufacturing delays (multiple countries affected)	Date of shortage: Mid June 2020 Expected return date: February 2022	Last updated: 18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion PA0549/030/002	Hydromorphone	Manufacturing delays (multiple countries affected)	Date of shortage: Mid August 2020 Expected return date: February 2022	Last updated: 18th October 2021
Imodium Plus 2mg/125mg Tablets PA0330/050/001	Loperamide & simeticone	Manufacturing delay	Date of shortage: 11th October 2021 Expected return date: Week commencing 22nd November 2021	Last updated: 20th October 2021
Innohep 10,000 IU/ml Solution for Injection PA0046/060/002	Tinzaparin sodium	Unexpected increase in demand (multiple countries affected)	Date of shortage: 20th September 2021 Expected return date: Mid-November 2021	Last updated: 23rd September 2021
Instanyl 50mcg Nasal Spray EU/1/09/531/010-013	Fentanyl	Quality issue (multiple countries affected)	Date of shortage: 1st August 2021 Expected return date: February 2022	Last updated: 20th August 2021
Instanyl 100mcg Nasal Spray EU/1/09/531/014-017	Fentanyl	Quality issue (multiple countries affected)	Date of shortage: 2nd April 2021 Expected return date: February 2022	Last updated: 20th August 2021
Instanyl 200mcg Nasal Spray EU/1/09/531/018-021	Fentanyl	Quality issue (multiple countries affected)	Date of shortage: 2nd April 2021 Expected return date: February 2022	Last updated: 20th August 2021
Invokana 300mg Film Coated Tablets EU/1/13/884/005-008	Canagliflozin	Unexpected increase in demand	Date of shortage: 18th October 2021 Expected return date: Early November 2021	Last updated: 12th October 2021
Letrozole 2.5mg Film Coated Tablets PA2315/109/001	Letrozole	Awaiting information	Date of shortage: Week commencing 25th October 2021 Expected return date: End November 2021	Last updated: 18th October 2021
Letrozole 2.5mg Film Coated Tablets PA0126/198/001	Letrozole	Manufacturing delays	Date of shortage: 22nd October 2021 Expected return date: 22nd December 2021	Last updated: 18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets PA0749/085/001	Letrozole	API unavailability (multiple countries affected)	Date of shortage: Week commencing 9th August 2021 Expected return date: January 2021	Last updated: 5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet PA0711/051/002	Lisinopril & Hydrochlorothiazide	Manufacturing delays	Date of shortage: 8th September 2020 Expected return date: Week commencing 1st November 2021	Last updated: 20th October 2021
Losartan 50mg Tablet PA2315/059/002	Losartan	Manufacturing delays	Date of shortage: 25th September 2019 Expected return date: Unknown at present	Last updated: 13th April 2021
Losartan 100mg Tablet PA2315/059/003	Losartan	Manufacturing delays	Date of shortage: October 2019 Expected return date: Unknown at present	Last updated: 13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film-Coated Tablets PA0749/026/001	Losartan & Hydrochlorothiazide	Quality issue	Date of shortage: Late October 2021 Expected return date: March 2022	Last updated: 22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets PA0749/026/002	Losartan & Hydrochlorothiazide	Quality issue	Date of shortage: Late October 2021 Expected return date: March 2022	Last updated: 22nd October 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection PA1691/025/002	Bupivacaine & adrenaline	Manufacturing delay (multiple countries affected)	Date of shortage: 1st July 2021 Expected return date: Unknown at present	Last updated: 24th September 2021
Mefac 250mg Capsule PA0074/015/001	Mefenamic acid	Manufacturing delays	Date of shortage: End of June 2019 Expected return date: Unknown at present	Last updated: 23rd April 2021
Metaraminol 10mg/ml Solution for Injection or Infusion PA22893/001/001	Metaraminol	Awaiting update	Date of shortage: Early April 2021 Expected return date: Awaiting update	Last updated: 30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution PA23081/008/001	Metformin	Regulatory Issue	Date of shortage: 13th August 2021 Expected return date: Unknown at present	Last updated: 10th August 2021
Mydrilate 1.0% w/v Eye Drops PA22709/003/002	Cyclopentolate	Manufacturing delay	Date of shortage: Early September 2021 Expected return date: Mid-October 2021	Last updated: 27th September 2021
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion PA0073/111/002	Naloxone	Manufacturing delay	Date of shortage: 18th October 2021 Expected return date: 3rd December 2021	Last updated: 19th October 2021
Nanocis 0.24mg Kit for Radiopharmaceutical Preparation PA0677/006/001	Rhenium sulphide	Awaiting information	Date of shortage: Week commencing 20th September 2021 Expected return date: Week commencing 8th November 2021	Last updated: 1st October 2021
Odrik 2mg Hard Capsule PA2010/005/003	Trandolapril	Manufacturing delays	Date of shortage: 5th October 2021 Expected return date: Late October 2021	Last updated: 28th September 2021
Oramox 125mg/5ml Powder for Oral Suspension PA0298/019/001	Amoxicillin	Unexpected increase in demand	Date of shortage: 22nd October 2021 Expected return date: Unknown at present	Last updated: 19th October 2021
OxyContin 5mg Prolonged Release Tablets PA1688/005/001	Oxycodone	Manufacturing delays	Date of shortage: 18th October 2021 Expected return date: Early November 2021	Last updated: 12th October 2021
OxyNorm Dispersa 5mg Orodispersible Tablets PA1688/006/007	Oxycodone	Unexpected increase in demand	Date of shortage: 5th October 2021 Expected return date: 4th November 2021	Last updated: 18th October 2021
OxyNorm Dispersa 10mg Orodispersible Tablets PA1688/006/008	Oxycodone	Manufacturing delays	Date of shortage: 18th October 2021 Expected return date: Unknown at present	Last updated: 12th October 2021
OxyNorm Dispersa 20mg Orodispersible Tablets PA1688/006/009	Oxycodone	Manufacturing delays	Date of shortage: 26th October 2021 Expected return date: February 2022	Last updated: 20th October 2021
Palexia 4mg/ml Oral Solution PA2242/012/010	Tapentadol hydrochloride	Quality issue (multiple countries affected)	Date of shortage: 15th February 2021 Expected return date: Unknown at present	Last updated: 22nd February 2021
Paralief 500mg Tablets 24 pack only PA0126/020/001	Paracetamol	API unavailability	Date of shortage: Week commencing 23rd August 2021 Expected return date: 27th October 2021	Last updated: 28th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w PA0278/017/002	Hydrocortisone & Lidocaine Hydrochloride	Manufacturing delays	Date of shortage: February 2021 Expected return date: January 2022	Last updated: 8th April 2021
Qlaira Film Coated Tablets PA1410/058/001	Estradiol	API unavailability	Date of shortage: Mid November 2021 Expected return date: Q2 2022	Last updated: 7th October 2021 HCP letter
Questran 4g Powder for Oral Suspension PA2239/005/001	Colestyramine	Manufacturing delays (multiple countries affected)	Date of shortage: Mid June 2019 Expected return date: January 2022	Last updated: 30th March 2021
Rifater 50mg/300mg/120mg Tablets PA0822/143/002	Isoniazid & Pyrazinamide & Rifampicin	Quality issue (multiple countries impacted)	Date of shortage: 23rd July 2021 Expected return date: 26th October 2021	Last updated: 18th October 2021 AMRIC guidance V3
Rosuvastatin 5mg Film Coated Tablets PA2315/068/001	Rosuvastatin	Quality issue	Date of shortage: 27th August 2021 Expected return date: Q2 2022	Last updated: 30th August 2021
Rosuvastatin 10mg Film Coated Tablets PA2315/068/002	Rosuvastatin	Quality issue	Date of shortage: 27th August 2021 Expected return date: Q2 2022	Last updated: 30th August 2021
Rosuvastatin 20mg Film Coated Tablets PA2315/068/003	Rosuvastatin	Distribution issue	Date of shortage: 18th October 2021 Expected return date: Early January 2022	Last updated: 21st October 2021
Rosuvastatin 40mg Film Coated Tablets PA2315/068/004	Rosuvastatin	Distribution issue	Date of shortage: 18th October 2021 Expected return date: Early January 2022	Last updated: 21st October 2021
Sevelamer Carbonate 800mg Film Coated Tablets PA0577/205/001	Sevelamer	Manufacturing delays	Date of shortage: Late October Expected return date: Unknown at present	Last updated: 22nd October 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension PA22906/001/001	Zinc oxide & Dimethicone	Manufacturing delays	Date of shortage: October 2019 Expected return date: Mid-December 2021	Last updated: 22nd October 2021
Stesolid Rectal Solution 5mg PA2315/137/001	Diazepam	Manufacturing delays	Date of shortage: Late August 2021 Expected return date: November 2021	Last updated: 12th August 2021
Stesolid Rectal Solution 10mg PA2315/137/002	Diazepam	Manufacturing delays	Date of shortage: Week commencing 19th July 2021. Expected return date: November 2021	Last updated: 21st July 2021
Targin 20mg/10mg Prolonged Release Tablets PA1688/010/001	Oxycodone & Naloxone	Shipping delays	Date of shortage: 27th September 2021 Expected return date: 28th October 2021	Last updated: 22nd October 2021
Telmisartan Rowa 40mg Tablets PA0074/078/002	Telmisartan	Unexpected increase in demand	Date of shortage: 7th September 2021 Expected return date: Late November 2021	Last updated: 20th October 2021
Tevanate Once Weekly 70mg Tablets PA0749/016/001	Alendronic acid	API unavailability	Date of shortage: 6th September 2021 Expected return date: Late November 2021	Last updated: 23rd August 2021
Tracrium 10 mg/ml, Solution for injection or infusion (25ml ampoule) PA1691/029/002	Atracurium	Unexpected increase in demand	Date of shortage: 24th September 2021 Expected return date: 20th November 2021	Last updated: 24th September 2021
Trandate 200mg Film Coated Tablet PA1638/006/003	Labetalol hydrochloride	Manufacturing delays (multiple countries affected)	Date of shortage: July 2019 Expected return date: End October 2021	Last updated: 11th October 2021
TPN – various B. Braun products	Various	Manufacturing delays	Date of shortage: 4th October 2021 Expected return date: Unknown at present	Last updated: 5th October 2021 HCP letter
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment PA22650/004/001	Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride	Regulatory issue	Date of shortage: Late September 2021 Expected return date: Late December 2021	Last updated: 15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets PA1688/011/001

Date of shortage:
20th October 2021

Expected return date:
Unknown at present

Anapen 300 micrograms in 0.3ml solution for injection in a pre-filled syringe

Contact us:

Medicinal Product Shortages Unit
Health Products Regulatory Authority
Kevin O’Malley House
Earlsfort Terrace,
Dublin 2
Tel: +353 1 676 4971
Fax: +353 1 676 7836
shortages@hpra.ie

Medicinal Product Shortages

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