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Medicines Shortages

The HPRA is responsible for coordinating the management of human medicine shortages on the Irish market. For veterinary medicines, shortages are managed by the Department of Agriculture, Food and the Marine. 

The definition of a shortage is when the supply of a medicinal product is inadequate to meet the needs of the patient. 

How are medicinal product shortages handled in Ireland?

The HPRA works with various stakeholders, including manufacturers, wholesale distributors, marketing authorisation holders, healthcare professionals, the Health Service Executive, patients and representative groups to respond to potential shortages and reduce the impact of shortages on patients. A framework for a multi-stakeholder approach to handling shortages of human medicinal products has been developed and published.

The framework aims to help prevent shortages and reduce patient impact by coordinating the management of potential or actual shortages as they arise. You can see the shortages case study on Adrenaline auto-injectors (AAIs) as an example of how the framework operates in practice. 

Mitigation and prevention strategies

The HPRA has reviewed data from the first two years of operation of the shortage framework to help develop future strategies for handling shortages and their prevention in Ireland. Following consultation with stakeholders, the Two-year Review has been published and outlines the strategy for the next phase of the framework.

 

Information on reporting shortages for:

Marketing Authorisation Holders

Please complete the Notification of medicinal product shortage from marketing authorisation holder form and return to  shortages@hpra.ie and to the HSE Corporate Pharmaceutical Unit.

Wholesale Distributors and Manufacturers

Please complete the Report of medicinal product shortage affecting the Irish market from wholesale distributors and manufacturers form and return this form to  shortages@hpra.ie.

Patients and Healthcare Professionals

Please complete the Report of medicinal product shortage affecting the Irish market from patients and healthcare professionals form and return to  shortages@hpra.ie. When completing this form, please include as much information as possible.

Veterinary Medicines

Please contact the Department of Agriculture, Food and the Marine.

 

Current and resolved shortages

The HPRA publishes a list of shortages currently affecting the Irish market that have been notified to us and that may have a medium or high impact on patients. This list can be found below. More information on the impact level can be found in the framework for a multi-stakeholder approach to handling shortages of human medicinal products.

The HPRA maintains a consolidated list of resolved shortages for a period of six months. Details of shortages that have been resolved in the last six months can be found here.


Please use search function below to find relevant product or active ingredient


Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abidec Multivitamin Oral Drops Solution 

PA1186/001/001
  Various Regulatory issue Date of shortage: 
18th July 2022

Expected return date: 
9th December 2022		 Last updated: 
23rd November 2022
Abstral 100mcg Sublingual Tablets

PA2288/004/002
 Fentanyl  Unexpected increase in demand  Date of shortage: 
9th November 2022

Expected return date:
Week commencing 12th December 2022		 Last updated: 
9th November 2022 
Acerycal 10mg/10mg Tablets

PA0568/018/004
 Perindopril arginine & amlodipine
 Manufacturing delays   Date of shortage: 
24th November 2022

Expected return date:
Week commencing 12th December 2022 		 Last updated: 
24th December 2022 
Actilyse Cathflo 2mg Powder for Solution for Injection and Infusion

PA0775/011/001		 Alteplase
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
Week commencing 9th May 2022

Expected return date: 
2024 		 Last updated: 
10th May 2022

HCP letter
Adizem XL 120mg Prolonged Release Capsules

PA1688/001/004
 Diltiazem   Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
Week commencing 28th November 2022

Expected return date: 
5th December 2022
 Last updated: 
25th November 2022
Adizem XL 180mg Prolonged Release Capsules

PA1688/001/005
 Diltiazem  Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
Week commencing 28th November 2022

Expected return date: 
5th December 2022		 Last updated: 
25th November 2022
Amorolfine 5%w/v Medicated Nail Lacquer

PA0711/309/001
 Amorolfine  Manufacturing delays Date of shortage: 
Late August 2022

Expected return date: 
End of January 2023		 Last updated: 
23rd November  2022 
Antabuse 400mg Effervescent Tablets

PA1380/008/001
 Disulfiram
  API unavailability 

(multiple countries affected)		 Date of shortage: 
Week commencing 25th July 2022

Expected return date: 
Mid January 2023		 Last updated: 
13th October 2022
Areloger 7.5mg Tablets

PA0577/057/001
  Meloxicam Manufacturing delays
 Date of shortage: 
Mid April 2022

Expected return date: 
Awaiting update		 Last updated: 
1st November 2022
Areloger 15mg Tablets

PA0577/057/002
  Meloxicam Manufacturing delays  Date of shortage:
End May 2022

Expected return date 
Awaiting update		  Last updated: 
1st November 2022
Artelac 3.2mg/ml Eye Drops, Solution 

PA23259/004/001
 Hypromellose
 Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
Late July 2022

Expected return date: 
January 2023		 Last updated: 
18th November 2022
Astilin 10mg Tablet

PA23163/001/001
 Amitriptyline  Manufacturing delay   Date of shortage: 
Week commencing 6th June 2022

Expected return date: 
Early December 2022		 Last updated: 
22nd  November 2022
Ativan 1mg Tablets

PA0822/090/001
 Lorazepam  Manufacturing delay

(multiple countries affected)		 Date of shortage:
24th November 2022

Expected return date: 
Week commencing 2nd January 2023 		 Last updated: 
25th November 2022 
Atenomel 50mg Tablets

PA0126/069/001
 Atenolol Unexpected increase in demand  Date of shortage: 
30th November 2022

Expected return date: 
Early June 2023 		 Last updated: 
23rd November 2022 
Atorvastatin Clonmel 80mg Film Coated Tablets

PA0126/271/004
  Atorvastatin  API unavailability   Date of shortage: 
24th October 2022

Expected return date: 
December 2022 		 Last updated: 
22nd November 2022
Atorvastatin Mylan 40mg Film Coated Tablets

PA0577/118/003
  Atorvastatin Manufacturing delay Date of shortage: 
Late October 2022

Expected return date: 
March 2023 		 Last updated: 
7th November 2022 
Atorvastatin Mylan 80mg Film Coated Tablets

PA0577/118/004
  Atorvastatin Manufacturing delay Date of shortage:
September 2022

Expected return date: 
March 2023		 Last updated: 
7th November 2022 
Azithromycin Clonmel 250mg Film Coated Tablets

PA0126/150/001
 Azithromycin  Quality issue 

(multiple countries impacted)		 Date of shortage: 
Week commencing 18th April 2022

Expected return date: 
Q1 2023		 Last updated: 
10th November 2022
Bactroban 2% w/w Ointment

PA1077/094/001
 Muripocin Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
18th November 2022

Expected return date: 
2024		 Last updated: 
21st November 2022 
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
2023		 Last updated:
24th January 2022
Brolene 0.1% w/v Eye Drops Solution

PA0126/357/001
 Propamidine
 Unexpected increase in demand Date of shortage: 
14th November 2022

Expected return date: 
Mid December 2022
 Last updated: 
23rd November 2022 
Brolene 0.15% w/w Eye Ointment

PA0126/357/002
 Dibromopropamidine
 Unexpected increase in demand Date of shortage: 
21st March 2022

Expected return date: 
23rd December 2022 		 Last updated: 
23rd November 2022 
Brufen 400mg Film-Coated Tablets

PA2010/002/001
 Ibuprofen  Unexpected increase in demand  Date of shortage: 
18th August 2022

Expected return date: 
December 2022 		 Last updated: 
14th September 2022 
Caelyx 2mg/ml
Pegylated Liposomal Concentrate for Solution

(25ml presentation)

EU/1/96/011/003-004
 Doxorubicin Manufacturing delays

(multiple countries affected)		 Date of shortage: 
Late October 2022

Expected return date:
2023 		 Last updated: 
10th October 2022 
Calcichew 500mg Chewable Tablets

PA2239/013/001
 Calcium carbonate  Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
End of October 2022

Expected return date: 
End of January 2023 		 Last updated: 
22nd November 2022 
Calcium Acetate 500mg Tablets

PA0281/063/001
 Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
Unknown at present		 Last updated: 
9th August 2022
Calcipotriol/Betamethasone Rowex 50mcg/g + 0.5mg/g Ointment

PA0711/254/001
 Calcipotriol & betamethasone
 Manufacturing delays  Date of shortage: 
2nd August 2022

Expected return date: 
Mid December 2022		 Last updated: 
23rd November 2022
Calvepen 333mg Tablets

PA0126/137/001
 Phenoxymethylpenicillin 
 Manufacturing delays Date of shortage: 
24th October 2022

Expected return date: 
Awaiting update		 Last updated: 
10th November 2022
Canesten Thrush Cream

PA1410/039/012		  Clotrimazole Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
15th September 2022 

Expected return date: 
Awaiting update		 Last updated: 
18th November 2022
Cefotaxime 1g Powder for solution for injection or infusion

PA0281/223/002 
 Cefotaxime Manufacturing delays  Date of shortage: 
30th November 2021 

Expected return date: 
Unknown at present 
 Last updated: 
17th June 2022
Ceftazidime 2g Powder for Solution for Injection or Infusion

PA0281/224/002
 Ceftazidime  Unexpected increase in demand   Date of shortage: 
End August 2022

Expected return date:
Mid December 2022		 Last updated: 
7th November 2022
Ceftriaxone 1g Powder for solution for injection or infusion

PA0281/225/001
 Ceftriaxone
 Manufacturing delays  Date of shortage: 
Early August 2022

Expected return date: 
December 2022		 Last updated: 
19th October 2022
Centrax 10mg Tablets

PA0822/010/001
 Prazepam
 Quality issue

(multiple countries affected) 		 Date of shortage: 
End June 2022 

Expected return date: 
Late 2023		 Last updated: 
8th September 2022
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Clarithromycin 500mg Film Coated Tablets

PA2315/136/004
  Clarithromycin Unexpected increase in demand  Date of shortage: 
28th November 2022

Expected return date; 
Early January 2023		 Last updated: 
21st November 2022 
Clonactil 25mg Film Coated Tablets

PA0126/026/003
 Chlorpromazine
 Manufacturing delay  Date of shortage: 
30th November 2022

Expected return date: 
Early January 2022		 Last updated: 
23rd November 2022
Clopidogrel 75mg Film-Coated Tablets

PA2315/198/001
 Clopidogrel  Quality issue  Date of shortage:
26th September 2022

Expected return date: 
December 2022		 Last updated: 
19th September 2022 
Clonazepam Rosemont 0.5mg/5 ml Oral Solution

PA23081/009/001
 Clonazepam Unexpected increase in demand Date of shortage: 
Week commencing 26th September 2022 

Expected return date: 
Awaiting update		 Last updated: 
25th November 2022
Co-amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion

PA2220/002/001
 Amoxicillin & clavulanic acid
 Manufacturing delay  Date of shortage: 
Late October 2022 

Expected return date:
Late November 2022 
 Last updated: 
7th November 2022 
Co-Amoxiclav Teva 500 mg/100 mg Powder for Solution for Injection/Infusion

PA0749/011/001
 Amoxicillin & clavulanic acid
 Quality issue

(multiple countries affected) 		 Date of shortage: 
19th September 2022

Expected return date: 
Awaiting update		 Last updated: 
18th November 2022
Cosartal Plus 50mg/12.5mg Film Coated Tablets

PA2315/190/001
 Losartan & hydrochlorothiazide
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Early February 2022

Expected return date: 
Awaiting update 
 Last updated: 
1st July 2022
Cosartal Plus 100mg/25mg Film Coated Tablets

PA2315/190/002
 Losartan & hydrochlorothiazide
 Quality issue

(multiple countries affected)		 Date of shortage: 
Early February 2022 

Expected return date: 
Awaiting update		 Last updated: 
1st July 2022
Cozaar 12.5mg Film-Coated Tablets

PA23198/002/001     
 Losartan  Quality issue Date of shortage: 
Week commencing 24th October 2022

Expected return date: 
Late November 2022		 Last updated: 
17th October 2022 
Cyklokapron 500mg Film Coated Tablets

PA2010/055/001
 Tranexamic acid
 Manufacturing delay  Date of shortage: 
23rd November 2022

Expected return date: 
End of December 2022 		 Last updated: 
25th November 2022 
Dalacin T Topical Lotion 10mg/ml Cutaneous Emulsion

PA0822/121/001
 Clindamycin  Manufacturing delays Date of shortage: 
14th October 2022

Expected return date: 
Awaiting update		 Last updated: 
11th November 2022
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
Late 2023		 Last updated:
9th February 2022 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Difflam Spray, 0.15% w/v, Oromucosal Spray

PA2010/030/003
 Benzydamine
 Manufacturing delays Date of shortage: 
Early August 2022

Expected return date: 
Awaiting update		 Last updated: 
11th November 2022
Dioralyte Citrus Powder for Oral Solution

PA23180/006/002
 Sodium chloride, potassium chloride, glucose & disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
Q1 2023
 Last updated: 
17th October 2021
Dioralyte Blackcurrant Powder for Oral Solution

PA23180/006/001
 Sodium chloride, potassium chloride,
glucose & disodium hydrogen citrate
 Manufacturing delays Date of shortage: 
July 2022 

Expected return date: 
Q4 2022		 Last updated: 
17th October 2022 
Dioralyte Natural, Powder for Oral Solution 

PA23180/007/001
 Sodium chloride, potassium chloride, glucose & disodium hydrogen citrate
 Manufacturing delays  Date of shortage:
June 2022

Expected return date:
Q1 2023 		 Last updated:
17th October 2022 
Dioralyte Rebalance Blackcurrant Powder for Oral Solution

PA23180/023/001
 Sodium chloride, potassium chloride, glucose & disodium hydrogen citrate
 Manufacturing delays  Date of shortage: 
September 2022

Expected return date: 
Q1 2023		 Last updated: 
17th October 2022 
Dioralyte Rebalance Citrus Powder for Oral Solution

PA23180/023/002
 Sodium chloride, potassium chloride, glucose & disodium hydrogen citrate  Manufacturing delays Date of shortage: 
September 2022

Expected return date: 
Q4 2023		 Last updated: 
17th October 2023 
Dioralyte Rebalance Natural Powder for Oral Solution

PA23180/023/003
 Sodium chloride, potassium chloride, glucose & disodium hydrogen citrate  Manufacturing delays Date of shortage: 
September 2022

Expected return date: 
Q1 2023
 Last updated: 
17th October 2022 
Dipentum 250mg Capsules

PA22657/001/001
 Olsalazine
 Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early September 2022

Expected return date: 
Q3 2023 		 Last updated: 17th October 2022 
Dipentum 500mg Tablets

PA22657/001/002
  Olsalazine
 Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
Early September 2022

Expected return date: 
Q3 2023 		 Last updated: 
17th October 2022 
Dukoral

EU/1/03/263/002
 Cholera vaccine Unexpected increase in demand 

(multiple countries affected) 		 Date of shortage: 
1st September 2022

Expected return date:
January 2023		 Last updated: 
16th September 2022
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emtricitabine/Tenofovir disoproxil Mylan 200 mg/245mg Film Coated Tablets

EU/1/16/1133/001-009
 Emtricitabine & tenofovir   Manufacturing delays Date of shortage:
28th October 2022

Expected return date: 
Mid December 2022 		 Last updated:
3rd November 2022 
Emtricitabine/Tenofovir disoproxil Accordpharma 200mg/245mg Film Coated Tablets

PA2315/200/002
 Emtricitabine & tenofovir  Manufacturing delays Date of shortage: 
24th May 2022

Expected return date: 
Mid December 2022		 Last updated: 
24th November 2022
Enerzair Breezhaler 114mcg /46mcg/136mcg Inhalation Powder 

EU/1/20/1438/003
 Indacaterol, glycopyrronium & mometasone  Manufacturing delays

(multiple countries affected)		 Date of shortage: 
20th October 2022

Expected return date: 
25th November 2022		 Last updated: 
20th October 2022 
Entecavir Accord 0.5 mg film-coated tablets 

EU/1/17/1211/001
  Entecavir Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
21st November 2022

Expected return date: 
March 2023
 Last updated: 
16th November 2022
Estradot 37.5mcg/24 hours, Transdermal Patch

PA0896/010/001
  Estradiol Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
15th November 2022

Expected return date: 
21st December 2022		 Last updated: 
17th October 2022

HSE guidance 1

HSE guidance 2

HCP letter
Estradot 50mcg/24 hours, Transdermal Patch

PA0896/010/002
  Estradiol Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
16th November 2022 

Expected return date: 
Awaiting update
 Last updated: 
21st November 2022

HSE guidance 1

HSE guidance 2

HCP letter
Estradot 75mcg/24 hours, Transdermal Patch 

PA0896/010/003		 Estradiol  Unexpected increase in demand

(multiple countries affected) 		 Date of shortage: 
15th October 2022

Expected return date: 
Awaiting update		 Last updated: 
21st November 2022

HSE guidance 1

HSE guidance 2

HCP letter
Estradot 100mcg/24 hours, Transdermal Patch

PA0896/010/004
  Estradiol Unexpected increase in demand 

(multiple countries affected) 		 Date of shortage: 
15th November 2022

Expected return date: 
Awaiting update		 Last updated: 
21st November

HSE guidance 1

HSE guidance 2

HCP letter
Etoricoxib 60mg Film Coated Tablets

PA0711/232/002
 Etoricoxib
 Manufacturing delays  Date of shortage: 
Late August 2022

Expected return date:
Early January 2023		 Last updated: 
9th November 2022 
Exforge FCT 5 mg /80 mg

EU/1/06/370/003
 Amlodipine & Valsartan Manufacturing delays Date of shortage: 
10th November 2022

Expected return date:
10th December 2022
 Last updated: 
16th November 2022 
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date:
Unknown at present		 Last updated: 
15th June 2022
Fentanyl 500mcg in 10ml Solution for Injection

PA0073/122/002
 Fentanyl  Regulatory issue  Date of shortage: 
8th July 2022 

Expected return date: 
Unknown at present
 Last updated: 
9th August 2022
Fesoterodine Aristo 4mg Prolonged Release Tablets

PA1983/007/001
  Fesoterodine
 Unexpected increase in demand  Date of shortage: 
17th October 2022

Expected return date:
Week commencing 5th December 2022		 Last updated:
28th November 2022 
Fesoterodine Aristo 8mg Prolonged Release Tablets

PA1983/007/002
  Fesoterodine Unexpected increase in demand   Date of shortage: 
17th October 2022

Expected return date:
Week commencing 5th December 2022		 Last updated: 
28th November 2022 
Flucloxacillin 1g Powder for Solution for Injection or Infusion

PA0281/122/003		 flucloxacillin
 Manufacturing delays Date of shortage: 
Week commencing 11th July 2022

Expected return date: 
Unknown at present		  Last updated: 
28th June 2022
Fluorouracil 25mg/ml Solution for Injection or Infusion

(100ml presentation only)

PA0822/223/001
 Fluorouracil  Quality issue Date of shortage:
25th February 2022

Expected return date: 
February 2023		 Last updated: 
5th September 2022

HCP letter
Frovex 2.5mg Film Coated Tablets

PA0865/009/001
  Frovatriptan Quality issue

(multiple countries affected)		 Date of shortage: 
11th January 2022 

Expected return date: 
September 2023		  Last updated:
23rd September 2022
Fucidin H 20mg/g + 10mg/g Cream

PA0046/005/005
 Hydrocortisone & fusidic acid 
 Manufacturing delays

(multiple countries affected)		 Date of shortage: 
8th October 2022

Expected return date: 
December 2022		 Last updated: 
10th October 2022
Fungizone 50 mg Powder for sterile concentrate

PA2239/004/001
 Amphotericin
Manufacturing delays		 Date of shortage: 
4th July 2022 

Expected return date: 
Awaiting update
 Last updated: 
18th October 2022
Furosemide 10mg/ml Solution for Injection or Infusion

(2ml presentation only)

PA2315/163/001
 Furosemide Unexpected increase in demand  Date of shortage: 
18th October 2022

Expected return date: 
January 2023
 Last updated: 
18th October 2022 
Gerax 500mcg Tablets

PA1445/024/002
 Alprazolam  Manufacturing delays  Date of shortage: 
July 2022

Expected return date: 
April 2023		 Last updated: 
5th October 2022
Golden Eye 0.1% w/v Eye Drops

PA22695/001/001
 Propamidine   Regulatory issue

(multiple countries affected)		 Date of shortage: 
16th November 2022

Expected return date: 
Q2 2023		 Last updated; 
24th November 2022 
Golden Eye 0.15% w/w Eye Ointment

PA22695/001/002
 Dibromopropamidine  Manufacturing delays

(multiple countries affected) 		 Date of shortage: 
16th November 2022

Expected return date: 
Early 2024 		 Last updated: 
24th November 2022 
Gyno-Pevaryl Once 150mg Vaginal Pessary

PA22650/006/001
 Econazole nitrate
 Manufacturing delays  Date of shortage: 
March 2022

Expected return date: 
Unknown at present 		 Last updated: 
9th March 2022 
Haemopressin 1mg Powder and Solvent for Solution for Injection

PA2325/004/001
 Terlipressin
 Quality issue   Date of shortage: 
13th October 2022

Expected return date: 
Awaiting update		 Last updated: 
18th November 2022 
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
Unknown at present 		 Last updated:
25th July 2022
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
Unknown at present		 Last updated:
25th July 2022
Ibandronic Acid Mylan 150mg Film coated Tablets

PA0577/111/001
 Ibandronic Acid API unavailability  Date of shortage: 
8th August 2022

Expected return date: 
Early December 2022		 Last updated:
13th October 2022
Inegy 10mg/20mg Tablets

PA23198/024/002
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
18th October 2022

Expected return date: 
January 2023		 Last updated: 
25th November 2022
Inegy 10mg/80mg Tablets

PA23198/024/004
 Ezetimibe & simvastatin
 Manufacturing delay  Date of shortage: 
25th November 2022

Expected return date: 
February 2023		 Last updated: 
25th November 2022
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
End February 2023		 Last updated: 15th July 2022
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
End February 2023		 Last updated:
15th July 2022
Ixprim 37.5 mg/325mg Effervescent Tablets

PA2242/006/002
 Paracetamol & tramadol 
 Unexpected increase in demand Date of shortage: 
2nd November 2022

Expected return date: 
5th December 2022 		 Last updated: 
22nd November 2022 
Kalcipos-D forte 500mg/800 IU Film Coated Tablets

PA2010/040/001
 Calcium & cholecalciferol
 Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
5th December 2022

Expected return date: 
January 2023		 Last updated: 
24th November 2022 
Keflex 125mg/5ml Powder for Oral Suspension

PA1226/002/002
 Cefalexin Unexpected increase in demand  Date of shortage: 
Week commencing 26th September 2022

Expected return date: 
Awaiting update		 Last updated: 
21st November 2022
Klaram LA 500 mg Prolonged Release Tablets

PA2315/133/001
 Clarithromycin  Unexpected increase in demand Date of shortage: 
28th November 2022

Expected return date: 
Early January 2023		 Last updated: 
21st November 2022 
Kopen 250mg Tablets

PA0298/007/001
 Phenoxymethylpenicillin 
 Unexpected increase in demand Date of shortage: 
Late April 2022

Expected return date: 
Unknown at present		 Last updated:
31st August 2022
Kopen Sugar Free 125mg/5ml Powder for Oral Solution

PA0298/007/002
 Phenoxymethylpenicillin 
 Unexpected increase in demand  Date of shortage: 
1st April 2022

Expected return date:
Unknown at present 		 Last updated:
31st August 2022
Kopen Sugar Free 250mg/5ml Powder for Oral Solution

PA0298/007/003
 Phenoxymethylpenicillin 
 Unexpected increase in demand Date of shortage: 
1st April 2022

Expected return date: 
Unknown at present		 Last updated: 
31st August 2022
Lasix 20mg/2ml Solution for Injection or Infusion

PA0540/052/002
 Furosemide  Manufacturing delay

(manufacturing delay) 		 Date of shortage: 
14th September 2022

Expected return date: 
Awaiting update		 Last updated: 
18th November 2022

HCP letter
Lercanidipine Clonmel 10mg Tablets 

PA0126/187/001
 Lercanidipine API unavailability   Date of shortage: 
Week commencing 10th October 2022

Expected return date:
Awaiting update		 Last updated:
24th November 2022
Lercanidipine Clonmel 20mg Tablets

PA0126/187/002
 Lercanidipine API unavailability   Date of shortage: 
End July 2022

Expected return date:
Awaiting update		 Last updated: 
24th November 2022
Letrozole Teva 2.5mg Film-Coated Tablets

PA0749/085/001
 Letrozole Awaiting information  Date of shortage: 
July 2022

Expected return date: 
Late November 2022		 Last updated: 
18th October 2022 
Levobupivacaine 2.5mg/ml Solution for Injection/Infusion

PA2059/009/003
  Levobupivacaine API unavailability

(multiple countries affected)		 Date of shortage: 
Week commencing 29th August 2022

Expected return date: 
Early January 2023		 Last updated: 
20th October 2022
Levobupivacaine 5mg/ml Solution for Injection/Infusion

PA2059/009/004
  Levobupivacaine API unavailability

(multiple countries affected)
 Date of shortage: 
Week commencing 5th September 2022

Expected return date: 
Early January 2023		 Last updated: 
20th October 2022
Levobupivacaine 7.5mg/mL Solution for Injection/Infusion

PA2059/009/005
 Levobupivacaine  API unavailability 

(multiple countries affected) 		 Date of shortage: 
Early December 2022

Expected return date: 
Early January 2022		 Last updated: 
24th November 2022 
Lopid 600mg Film-Coated Tablets

PA0822/014/002
 gemfibrozil
 Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
Week commencing 24th October 2022

Expected return date: 
Week commencing 28th November 2022 		 Last updated: 
25th October 2022 
Lyclear 5% w/w Dermal Cream

PA1077/066/001		  Permethrin Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
Week commencing 11th July 2022

Expected return date: 
January 2023		 Last updated: 
27th June 2022
Lyrica 50mg Capsules

EU/1/04/279/009
 Pregabalin
 Shipping delay  Date of shortage: 
23rd November 2022

Expected return date: 
End of December 2022 		 Last updated: 
25th November 2022 
Lyrica 75mg Capsules

EU/1/04/279/012
 Pregabalin  Shipping delay  Date of shortage: 
23rd November 2022

Expected return date:
End of December 2022		 Last updated: 
25th November 2022 
Lyrica 100mg Capsules

EU/1/04/279/015
 Pregabalin  Shipping delay  Date of shortage: 
23rd November 2022

Expected return date: 
End of December 2022  		 Last updated: 
25th November 2022 
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
Late January 2023
 Last updated: 
12th August 2022 
Maxilief Effervescent Tablets

(24 pack only)

PA0126/113/001
 Paracetamol, Codeine & Caffeine
 Manufacturing delays Date of shortage: 
18th October 2022

Expected return date:
Unknown at present		 Last updated: 
19th October 2022 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Menopur 75IU Powder and Solvent for Solution or Injection

PA1009/015/001
 Menotrophin  Quality issue

(multiple countries affected) 		 Date of shortage: 
Week commencing 31st October 2022

Expected return date:
Unknown at present		 Last updated:
4th November 2022 
Menopur 600IU Powder and Solvent for Solution or Injection

PA1009/015/002
  Menotrophin Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 31st October 2022

Expected return date:
Unknown at present
 Last updated:
4th November 2022
Menopur 1200IU Powder and Solvent for Solution or Injection

PA1009/015/003
  Menotrophin Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 31st October 2022

Expected return date:
Unknown at present
 Last updated: 
4th November 2022
Meronepem Aurobindo 1g Powder for Solution for Injection or Infusion 

PA1445/014/002		 Meropenem  Shipping delay  Date of shortage:
Week commencing 3rd October 2022

Expected return date: 
Awaiting update		 Last updated:
25th November 2022
Metalyse 50mg Powder and Solvent for Solution for Injection

EU/1/00/169/006
Tenecteplase		 Manufacturing delays

(multiple countries affected) 		 Date of shortage: 
29th July 2022 2022

Expected return date: 
2024		 Last updated: 
23rd September 2022

HCP letter
Methotrexate 2.5mg Tablets

PA2315/062/001
 Methotrexate  Unexpected increase in demand   Date of shortage: 
5th December 2022

Expected return date: 
August 2023		 Last updated: 
28th November 2022 
Methylthioninium Chloride Proveblue 5mg/ml solution for Injection

EU/1/11/682/001
 Methylthionium Regulatory issue  Date of shortage:
Week commencing 3rd October 2022

Expected return date: 
Unknown at present		 Last updated: 
28th September 2022 
Mydrilate 0.5% Eye Drops

PA22709/003/001
 Cyclopentolate  Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
17th November 2022

Expected return date: 
Unknown at present		 Last updated: 
21st November 2022
Mydrilate 1.0% Eye Drops

PA22709/003/002
 Cyclopentolate
 Manufacturing delays

(multiple countries affected)		 Date of shortage: 
17th November 2022

Expected return date: 
Unknown at present		 Last updated:
21st November 2022 
Milrinone 1 mg/ml Solution for Injection/Infusion Milrinone Distribution issue  Date of shortage:
16th November 2022

Expected return date: 
Week commencing 16th February 2023
 Last updated: 
16th November 2022
Minims Artificial Tears 0.35% w/w + 0.44% w/w Eye Drops, Solution

PA22698/009/001
 Sodium chloride & hydroxyethylcellulose
 Quality issue  Date of shortage:
April 2022

Expected return date: 
Awaiting update		 Last updated: 
18th November 2022
Mivacron 2mg/ml Solution for Injection

PA1691/031/001 
 Mivacurium chloride
 Manufacturing delays Date of shortage: 
20th June 2022

Expected return date: 
10th December 2022 		 Last updated: 
1st July 2022
Molipaxin 100mg Hard Capsules 

PA540/056/002
  Trazodone
 Manufacturing delays Date of shortage: 
20th June 2022

Expected return date: 
Early December 2022		 Last updated: 
10th October 2022

HCP letter
Monotrim 100mg Tablets

PA22643/002/002
 Trimethoprim
 Manufacturing delays  Date of shortage: 
July 2022

Expected return date: 
Awaiting update		 Last updated: 
26th October 2022
Monotrim 200mg Tablets

PA22643/002/003
 Trimethoprim
 Manufacturing delays  Date of shortage: 
August 2022

Expected return date: 
November 2022		 Last updated: 
3rd October 2022
Morphine Sulphate 10mg/ml Solution for Injection

PA0073/020/001
 Morphine   Manufacturing delays Date of shortage: 
25th July 2022

Expected return date: 
Mid December 2022		 Last updated: 
10th October 2022
Nasofan Aqueous 50mcg Nasal Spray Suspension

PA1986/084/001
  Fluticasone propionate API unavailability  Date of shortage: 
Week commencing 29th August 2022

Expected return date: 
Awaiting update		 Last updated:
26th October 2022
Navelbine 30mg Soft Capsules

PA0329/011/002
 Vinorelbine
 Unexpected increase in demand

(multiple countries affected) 		 Date of shortage: 
10th November 2022

Expected return date: 
March 2023 		 Last updated: 
25th November 2022 
Nipent 10mg Powder for Solution for Injection, Powder for Solution for Infusion

PA0822/228/001
 Pentostatin
 Quality issue

(multiple countries impacted)		 Date of shortage: 
1st November 2022

Expected return date: 
Week commencing 19th December 2022		 Last updated: 
3rd November 2022 

HCP letter
Norditropin FlexPro 15mg/1.5ml, Solution for Injection in Pre Filled Pen

PA0218/040/013
 Somatropin Manufacturing delay  Date of shortage: 
12th November 2022

Expected return date:
Early December 2022 		 Last updated: 
7th November 2022 
Normacol 62% w/w Granules

PA1336/007/001
 Sterculia  Quality issue

(multiple countries affected) 		 Date of shortage: 
14th October 2022

Expected return date: 
Unknown at present 		 Last updated: 
28th October 2022 
Normacol Plus Granules Sterculia 62% w/w Frangula 8% w/w

PA1336/008/001
 Sterculia & frangula
 Quality issue

(multiple countries affected) 		 Date of shortage: 
14th October 2022

Expected return date:
Unknown at present 		 Last updated: 
28th October 2022 
Nortem 20mg Tablets

PA1986/085/002
 Temazepam
  API unavailability

(multiple markets affected)		 Date of shortage: 
Week commencing 24th October 2022

Expected return date: 
Week commencing 23rd January 2023 		 Last updated: 
10th October 2022 
Nu-seals 300mg Gastro-Resistant Tablets

PA2325/010/002
  Acetylsalicylic acid
  Quality issue

(multiple countries affected)		 Date of shortage: 
15th August 2022

Expected return date:
Unknown at present 		 Last updated: 
16th September 2022 
Octreotide 500 micrograms/1 ml Solution for Injection

PA0822/218/004
 Octreotide Regulatory issue  Date of shortage: 
Week commencing 22nd August 2022

Expected return date: 
Unknown at present		 Last updated: 
21st October 2022
Ondansetron 2mg/ml Solution for Injection

(4ml presentation)

PA1122/004/001
 Ondansetron Unexpected increase in demand  Date of shortage: 
Week commencing 3rd October 2022

Expected return date: 
End of November 2022
 Last updated: 
7th November 2022
Ondansetron 2 mg/ml Solution for Injection or Infusion

(4ml presentation)

PA0577/083/001
  Ondansetron
 Manufacturing delay  Date of shortage: 
Late July 2022

Expected return date: 
End of November 2022		 Last updated:
7th November 2022 
Opticrom Allergy Single Dose 2% w/v Eye Drops, Solution

PA23180/010/003
 Sodium cromoglicate
 Quality issue

(multiple countries affected)		 Date of shortage: 
27th January 2022 

Expected return date:
Late January 2023		 Last updated: 
10th November 2022
Oxynorm 5mg hard capsules

PA1688/006/004
  Oxycodone Manufacturing delay
 Date of shortage: 
28th November 2022 

Expected return date: 
7th January 2023
 Last updated: 
16th November 2022
Oxynorm Dispersa 10mg Orodispersible tablets 

PA1688/006/008
  Oxycodone Manufacturing delay Date of shortage: 
21st November 2022 

Expected return date: 
January 2023
 Last updated: 
16th November 2022
Oxycodone hydrochloride 50mg/ml Solution for Injection or Infusion

PA0281/235/002
 Oxycodone  Manufacturing delays   Date of shortage: 
1st November 2021 

Expected return date: 
Unknown at present		 Last updated: 
23rd August 2022
Palladone 1.3mg Capsules

PA1688/007/001
  Hydromorphone Manufacturing delays Date of shortage:
Week commencing 8th August 2022

Expected return date: 
December 2022		 Last updated: 
13th October 2022
Pantoflux 40mg Gastro Resistant Tablets 

PA2315/187/002		 Pantoprazole  Distribution issue  Date of shortage: 
Week commencing 12th September 2022

Expected return date: 
December 2022 		 Last updated:
5th September 2022 
Paracetamol 500mg Film Coated Tablets

PA2315/065/003
 Paracetamol  Shipping delay  Date of shortage: 
Week commencing 21st November 2022

Expected return date: 
Mid December 2022 		 Last updated: 
24th November 2022 
Phenergan 25mg Film Coated Tablets

PA23180/011/002
 Promethazine API unavailability   Date of shortage: 
Week commencing 24th October 2022

Expected return date: 
December 2022		 Last updated: 
23rd November 2022 
Praxilene 100mg Capsules

PA2286/003/001
 Naftidrofuryl hydrogen oxalate  API unavailability

(multiple countries affected)		 Date of shortage: 
Mid August 2022

Expected return date: 
January 2023 		 Last updated: 
10th August 2022
Prednesol 5mg Tablets

PA1113/001/001
  Prednisolone API delay
 
(multiple countries affected)		 Date of shortage: 
24th October 2022

Expected return date:
28th November 2022		 Last updated: 
22nd November 2022
Prednisolone 1mg Tablets

PA0126/027/002
 Prednisolone Manufacturing delays  Date of shortage: 
13th July 2022

Expected return date: 
16th December 2022		 Last updated: 
18th November 2022
Prednisolone 5mg Tablets

PA0126/027/001
 Prednisolone  Manufacturing delays  Date of shortage: 
13th July 2022

Expected return date: 
16th December 2022
 Last updated: 
18th November 2022
Pregabalin Krka 75mg hard capsules

PA1347/050/003
  Pregabalin Unexpected increase in demand  Date of shortage: 
Week commencing 21st November 2022

Expected return date: 
End of December 2022 		 Last updated: 
10th November 2022 
Pregabalin Sandoz 75mg Capsules 

EU/1/15/1011/021
 Pregabalin  Manufacturing delays Date of shortage: 
2nd August 2022

Expected return date: 
End of December 2022		 Last updated: 
8th November 2022
Pregabalin Sandoz 100mg Capsules

EU/1/15/1011/038
  Pregabalin  Manufacturing delays  Date of shortage: 
4th October 2022

Expected return date: 
December 2022		 Last updated: 
23rd November 2022
Provigil 100 mg Tablets

PA0749/198/001
 Modafinil
 Unexpected increase in demand  Date of shortage: 
Week commencing 19th September 2022

Expected return date: 
Awaiting update		 Last updated:
18th November 2022
Quentiax SR 50mg Prolonged Release Tablets

PA1347/045/004
 Quetiapine Unexpected increase in demand  Date of shortage: 
3rd November 2022

Expected return date: 
Early December 2022 		 Last updated: 
10th November 2022 
Quetex XR 50mg Prolonged-Release Tablets

PA0711/258/001
 Quetiapine  Manufacturing delays  Date of shortage: 
4th October 2022
 

Expected return date: 
Awaiting update		 Last updated:
18th November 2022
Quofenix 450mg Tablet

EU/1/19/1393/002
 Delafloxacin Manufacturing delay  Date of shortage: 
July 2022

Expected return date:
Week commencing 19th December 2022 		 Last updated:
22nd November 2022
Radiopharmaceutical Kits for use with Technetium
 Technetium  Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
Week commencing 31st October 2022

Expected return date:
Early December 2022		 Last updated: 
22nd November 2022
Rapiscan 400mcg Solution for Injection

EU/1/10/643/001
  Regadenoson
 Quality issue

(multiple countries affected)		 Date of shortage: 
Late October 2022

Expected return date: 
March 2023		 Last updated: 
17th October 2022
Rifadin 150mg Capsules 
 
PA540/066/001
 Rifampicin  Unexpected increase in demand  Date of shortage: 
Week commencing 31st October 2022

Expected return date: 
Awaiting update		  Last updated: 
25th November 2022
Risonate Once Weekly 35mg Film Coated Tablets

PA0749/064/001
 Risedronate    API unavailability 

(multiple countries affected)		 Date of shortage: 
Week commencing 27th June 2022

Expected return date: 
Week commencing 26th December 2022		 Last updated: 
13th June 2022 
Rivotril 0.5mg Tablets

PA2239/020/001
 Clonazepam  Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
Week commencing 17th October 2022 

Expected return date: 
Late November 2022		 Last updated: 
25th October 2022 
Rowalief 500mg Film Coated Tablets

(300 pack)

PA0074/065/001
  Paracetamol Unexpected increase in demand  Date of shortage: 
Week commencing 3rd October 2022

Expected return date: 
End of December 2022		 Last updated:
23rd November 2022
Rotarix

EU/1/05/330/010
 Human rotavirus, live attenuated
 Manufacturing delays  Date of shortage: 
Week commencing 18th July 2022

Expected return date: 
Awaiting update		  Last updated: 
18th October 2022
Six Plus Parapaed Paracetamol Oral Suspension 250mg/5ml

PA0281/002/003
 Paracetamol Quality issue Date of shortage: 
January 2022 

Expected return date:
April 2023		 Last updated: 
21st November 2022
Sodium Iodide (I131) Capsule T

PA0690/006/002
 Sodium iodide (131 i)  Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
Late November 2022

Expected return date: 
Mid December 2022		 Last updated: 
22nd November 2022
Solpadeine Soluble Tablets

(24 pack only)

PA1186/011/001
 Paracetamol, codeine & caffeine
 Manufacturing delays 

(multiple countries affected) 		 Date of shortage:
Early November 2022

Expected return date:
Early December 2022		 Last updated: 
25th October 2022
Spasmonal 60mg Capsules

PA2010/043/001
 Alverine
 Manufacturing delay Date of shortage: 
23rd November 2022

Expected return date: 
February 2023 		 Last updated: 
25th November 2022 
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
25th July 2022
Targocid 200mg Powder and Solvent for Solution for Injection/infusion or oral solution 

PA0540/021/001
 Teicoplanin Quality issue

(multiple countries impacted) 		 Date of shortage: 
18 November 2022

Expected return date:
12cth December 2022
 Last updated: 
16th November 2022
Teicoplanin 400 mg Powder and Solvent for Solution for Injection/Infusion or Oral Solution

PA1122/009/002
 Teicoplanin Unexpected increase in demand  Date of shortage: 
28th October 2022

Expected return date: 
Week commencing 19th December 2022		 Last updated: 
28th November 2022 
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
 Alendronic acid  Manufacturing delays

(multiple countries affected) 		 Date of shortage: 
Week commencing 4th April 2022 

Expected return date: 
End of November 2022		 Last updated: 
21st October 2022
Tobi 300mg/5ml Nebuliser Solution

PA2010/063/001
 Tobramycin
 Manufacturing delay  Date of shortage: 
23rd November 2022

Expected return date:
February 2023 		 Last updated: 
25th November 2022 
Trandate 200mg Film Coated Tablets

PA1638/006/003
 Labetalol
 Manufacturing delay  Date of shortage: 
Early November 2022

Expected return date:
Mid 2023  		 Last updated: 
28th November 2022 
Triapin 2.5mg/2.5mg Prolonged Release Tablet

PA0540/082/001
 Felodipine & ramipril
 Regulatory issue

(multiple countries affected) 		 Date of shortage: 
21st November 2022

Expected return date:
January 2023		 Last updated: 
7th November 2022 
Tradol 50mg Effervescent Tablets 

PA0074/094/001
 Tramadol Unexpected increase in demand  Date of shortage:
Late August 2022

Expected return date: 
Early December 2022		 Last updated: 
23rd November 2022 
Uniphyllin Continus 300mg Prolonged Release Tablets

PA1688/011/001
 Theophylline  Shipment delay

(multiple countries affected) 		  Date of shortage: 
Week commencing 7th November 2022

Expected return date: 
Week commencing 28th November 2022		 Last updated: 
23rd 2022 
Valaciclovir 500mg Film-Coated Tablets

PA2315/102/001
 Valaciclovir
 API unavailability  Date of shortage:
Week commencing 26th September 2022

Expected return date: 
December 2022 		 Last updated:
14th September 2022 
Warfant 1mg Tablets

PA0073/139/001
 Warfarin  API unavailability  Date of shortage: 
End September 2022

Expected return date: 
February 2023		 Last updated: 
25th November 2022 
Zydol 50mg Hard Capsules

PA2242/005/001
 Tramadol Unexpected increase in demand Date of shortage: 
Late July 2022

Expected return date: 
Awaiting update		 Last updated: 
18th November 2022 
Xeljanz 5mg Film Coated Tablets

EU/1/17/1178/003
 Tofacitinib Manufacturing delays Date of shortage: 
Week commencing 7th November 2022

Expected return date:
Awaiting update		 Last updated: 
18th November 2022
Xomolix 2.5mg/ml Solution for Injection

PA2288/003/002
 Droperidol  Quality issue

(multiple countries affected)		 Date of shortage: 
29th May 2021

Expected return date: 
Unknown at present  		 Last updated: 
2nd July 2021
Xylocaine 2% with Adrenaline (Epinephrine) (1:200,000) Solution for Injection

PA1691/027/001
 Lidocaine and adrenaline Manufacturing delay 

(multiple countries impacted)		 Date of shortage: 
2nd February 2022

Expected return date: 
Late December 2022		 Last updated: 
12th August 2022
Xymel 50mg Capsules

PA0126/099/001
 Tramadol  Unexpected increase in demand  Date of shortage: 
Week commencing 29th August 2022

Expected return date:
Unknown at present		 Last updated: 
30th August 2022 
Zithromax Powder for Oral Suspension 200mg/5ml

15ml presentation

PA0822/191/002
 Azithromycin  Unexpected increase in demand  Date of shortage:
Early October 2022

Expected return date: 
Awaiting update		 Last updated: 
18th October 2022
Zolmitriptan  2.5mg Orodispersible Tablets

PA2315/232/001
  Zolmitriptan API unavailability   Date of  shortage: 
Week commencing 31st October 2022

Expected return date: 
December 2022		 Last updated: 
17th October 2022 
Zyban 150mg Prolonged Release Tablets

PA1077/017/001
  Brupropion Quality issue

(multiple countries affected) 		 Date of shortage:
1st November 2022

Expected return date: 
Unknown at present 		 Last updated: 
7th November 2022 

Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL



Date of shortage: 
2nd July 2021

Expected return date: 
Unknown at present  
Date of shortage: 
2nd July 2021

Expected return date: 
Unknown at present  

Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 

Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abstral 100mcg Sublingual Tablets

PA2288/004/002
  Fentanyl  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
3rd September 2021 

Expected return date: 
Week commencing 1st October 2021		 Last updated: 
22nd October 2021
Abstral 200mcg Sublingual Tablets

PA2288/004/003
 Fentanyl Manufacturing delays 

(multiple countries affected)		 Date of shortage:
15th August 2021

Return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 300mcg Sublingual Tablets

PA2288/004/004
 Fentanyl  Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
5th October 2021

Expected return date: 
Week commencing 25th October 2021
 Last updated: 
22nd October 2021
Abstral 400mcg Sublingual Tablets

PA2288/004/005
 Fentanyl  Manufacturing delays 

(multiple countries affected)
 Date of shortage: 
4th October 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Abstral 600mcg Sublingual Tablets

PA2288/004/006
 Fentanyl   Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
2nd September 2021 

Expected return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 700mcg Sublingual Tablets

PA2288/004/007
 Fentanyl Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
2nd September 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Adizem-XL 180mg Prolonged Release Capsules

PA1688/001/005
 Dilitazem  Manufacturing delays Date of shortage: 
1st October 2021

Expected return date: 
November 2021 		 Last updated: 
27th September 2021
Amitriptyline 25mg Film Coated Tablets

PA0126/041/001
 Amitriptyline
 API unavailability Date of shortage: 
2nd September 2021 

Expected return date: 
Late October 2021		 Last updated: 
7th September 2021 

HCP letter
Astilin 10mg Tablets

PA23163/001/001
 Amitriptyline  Awaiting update Date of shortage: 
27th August 2021

Expected return date: 
29th October 2021		 Last updated: 
5th October 2021

HCP letter
Ativan 4mg/ml Solution for Injection

PA0822/090/002 		 Lorazepam  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2020

Expected return date:
Unknown at present		 Last updated:
14th May 2021 
 
HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
2022		 Last updated:
3rd February 2021
Bendroflumethiazide 2.5mg Tablets

PA22749/021/001
 Bendroflumethiazide
  Regulatory issue Date of shortage:
3rd September 2021

Expected return date: 
Awaiting update		 Last updated: 
1st October 2021
Beromun 1mg Powder for Solution for Infusion

EU/1/99/097/001 		 Tasonermin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
December 2020

Expected return date:
November 2021		 Last updated:
1st June 2021
Calcium Acetate 500mg Tablets

PA0281/063/001
 Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
Late December 2021		 Last updated: 
30th September 2021
Canesten HC 1% w/w + 1% w/w Cream

PA1410/040/002
 Clotrimazole & Hydrocortisone  Manufacturing delays Date of shortage: 
30th September 2021 

Expected return date:
5th November 2021		 Last updated: 
22nd September 2021
Catapres Tablets 100mcg

PA2256/003/001
  Clonidine Manufacturing delays

(multiple countries affected)		 Date of shortage: 
25th July 2021

Expected return date: 
25th October 2021		 Last updated: 
21st June 2021 
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution

PA2299/005/001
 Chlorhexidine acetate & cetrimide
 Unexpected increase in demand Date of shortage: 
September 2021 

Expected return date: 
Mid November 2021 		 Last updated: 
20th October 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution

PA0281/124/001 		 Chlorpromazine hydrochloride  Manufacturing delays  Date of shortage:
End of February 2021

Expected return date:
End January 2022		 Last updated:
5th October 2021
 
HCP letter
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes 

PA0540/097/008
 Enoxaparin sodium  API unavailability   Date of shortage: 
22nd October 2021 

Expected return date: 
Unknown at present		 Last updated: 
13th October 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion

PA1457/001/001
 Amoxicillin & Clavulanic acid
 Manufacturing delays Date of shortage: 
13th October 2021 

Expected return date: 
Awaiting update		 Last updated: 
18th October 2021 
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion

PA1457/001/002		 Amoxicillin & clavalunic acid Unexpected increase in demand Date of shortage:
5th February 2020

Expected return date:
Awaiting update
 Last updated:
19th October 2021
CoAprovel 300mg/12.5mg Tablets

EU/1/98/086/004
 Irbesartan & Hydrochlorothiazide  Shipping delay  Date of shortage: 
5th November 2021

Expected return date: 
Late November 2021  		 Last updated: 
22nd October 2021 
Cyklokapron 100 mg/mL Solution for Injection/Infusion

PA0822/117/001
 Tranexamic acid Manufacturing delays Date of shortage: 
Week commencing 18th October 2021

Expected return date: 
Week commencing 15th November 2021 		 Last updated: 
5th October 2021 
Deslor 5mg Film Coated Tablets

PA0711/202/001
 Desloratidine Awaiting information   Date of shortage: 
19th September  2021  

Expected return date: 
Late December 2021		 Last updated: 
October 2021 
Desmopressin 100mcg/ml Nasal Drop Solution

PA1009/001/001 		 Desmopressin  Manufacturing delays due to quality issue

(multiple countries affected) 		 Date of shortage:
Mid December 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Dioralyte Blackcurrant Powder for Oral Solution (20 pack)

PA0540/098/001
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate  Unexpected increase in demand  Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021		 Last updated: 
30th September 2021
Dioralyte Citrus Powder for Oral Solution
(20 pack)

PA0540/098/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution
(6 pack)

PA0540/194/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Doxatan 4mg Tablets

PA0126/202/003 		 Doxazosin  Manufacturing delay   Date of shortage: 
4th October 2021

Expected return date:
Week commencing 1st November 2021		 Last updated: 
20th October 2021
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005		 Phenytoin Manufacturing delays

(multiple countries affected)		 Date of shortage:
Early November 2019

Expected return date:
Unknown at present		 Last updated:
4th June 2020
 
HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion

PA1852/002/001 		 Esomeprazole  Unavailability of API  Date of shortage:
Early October 2020

Expected return date:
Late November 2021		 Last updated:
12th October 2021
Ezetimibe Rowa 10mg Tablets

PA0074/074/001
 Ezetimibe Awaiting information  Date of shortage: 
19th October 2021 

Expected return date: 
Late November 2021 		 Last updated: 
21st October 2021
Ezetimibe Teva 10mg tablets

PA1986/012/001
 Ezetimibe  Quality Issue  Date of shortage: 
18th October 2021 

Expected return date: 
13th December 2021		 Last updated: 
4th October 2021
Ezetimibe 10mg tablets

PA0577/198/001
 Ezetimibe
 Manufacturing delays  Date of shortage: 
Late August 2021 

Expected return date: 
Early November 2021		 Last updated: 
4th October 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets

PA0711/262/001
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 22nd July 2021

Expected return date: 
October 2021		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date: 
End November 2021
 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets

PA1986/067/003
 Ezetimibe & simvastatin
 API unavailability

(multiple countries impacted) 		 Date of shortage: 
30th August 2021 

Expected return date: 
Awaiting update		 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets

PA0126/281/002
Ezetimibe & simvastatin
 Manufacturing delays   Date of shortage: 
Week commencing 20th September 2021

Expected return date: 
Unknown at present		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets

PA0126/281/004
 Ezetimibe & simvastatin
 Manufacturing delays Date of shortage: 
Week commencing 20th September 2021

Expected return date:  
Unknown at present		 Last updated: 
20th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection

PA0822/198/002
 Folinic Acid  Unexpected increase in demand Date of shortage: 
Week commencing 27th September 2021

Expected return date: 
Awaiting update		 Last updated:
18th October 2021
Fomicyt 40mg/ml Powder for Solution for Infusion

PA1972/001/001
 Fosfomycin sodium Regulatory issue  Date of Shortage: 
October 2021 

Expected return date: 
Unknown at present		 Last updated: 
12th October 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension

PA1142/014/001
 Gentamicin & Hydrocortisone Unavailability of API 

(multiple countries affected)		 Date of shortage: 
23rd August 2021

Expected return date:
Late November 2021		 Last updated: 
9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Imodium Plus 2mg/125mg Tablets

PA0330/050/001
 Loperamide & simeticone  Manufacturing delay  Date of shortage: 
11th October 2021 

Expected return date:
Week commencing 22nd November 2021		 Last updated: 
20th October 2021
Innohep 10,000 IU/ml Solution for Injection

PA0046/060/002
 Tinzaparin sodium
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
20th September 2021

Expected return date: 
Mid-November 2021
 Last updated: 
23rd September 2021
Instanyl 50mcg Nasal Spray 

EU/1/09/531/010-013
 Fentanyl  Quality issue 
(multiple countries affected)		 Date of shortage: 
1st August 2021 

Expected return date: 
February 2022
 Last updated: 
20th August 2021
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated: 
20th August 2021
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated:
20th August 2021
Invokana 300mg Film Coated Tablets

EU/1/13/884/005-008		 Canagliflozin
 Unexpected increase in demand  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021 		 Last updated: 
12th October 2021
Letrozole 2.5mg Film Coated Tablets

PA2315/109/001
 Letrozole  Awaiting information   Date of shortage: 
Week commencing 25th October 2021

Expected return date: 
End November 2021		 Last updated: 
18th October 2021 
Letrozole 2.5mg Film Coated Tablets

PA0126/198/001
 Letrozole  Manufacturing delays  Date of shortage: 
22nd October 2021 

Expected return date: 
22nd December 2021		 Last updated: 
18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets

PA0749/085/001
 Letrozole  API unavailability 

(multiple countries affected) 		 Date of shortage: 
Week commencing 9th August 2021

Expected return date: 
January 2021		 Last updated: 
5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet

PA0711/051/002 		 Lisinopril & Hydrochlorothiazide  Manufacturing delays  Date of shortage:
8th September 2020

Expected return date:
Week commencing 1st November 2021		 Last updated:
20th October 2021
Losartan 50mg Tablet 

PA2315/059/002 		 Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
Unknown at present 		 Last updated:
13th April 2021
Losartan 100mg Tablet

PA2315/059/003 		 Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film-Coated Tablets

PA0749/026/001
 Losartan & Hydrochlorothiazide
  Quality issue Date of shortage: Late October 2021  

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets

PA0749/026/002
 Losartan & Hydrochlorothiazide
 Quality issue  Date of shortage: 
Late October 2021

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
Unknown at present 
 Last updated: 
24th September  2021 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Metaraminol 10mg/ml Solution for Injection or Infusion 

PA22893/001/001		 Metaraminol  Awaiting update Date of shortage: 
Early April 2021 

Expected return date:
Awaiting update		 Last updated: 
30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution

PA23081/008/001
 Metformin  Regulatory Issue Date of shortage: 
13th August 2021

Expected return date: 
Unknown at present		 Last updated: 
10th August 2021
Mydrilate 1.0% w/v Eye Drops

PA22709/003/002
 Cyclopentolate Manufacturing delay  Date of shortage:
Early September 2021

Expected return date: 
Mid-October 2021		 Last updated: 
27th September 2021 
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion 

PA0073/111/002
 Naloxone Manufacturing delay  Date of shortage: 
18th October 2021

Expected return date: 
3rd December 2021 		 Last updated: 
19th October 2021
Nanocis 0.24mg Kit for Radiopharmaceutical Preparation

PA0677/006/001
 Rhenium sulphide
 Awaiting information  Date of shortage: 
Week commencing 20th September 2021 

Expected return date: 
Week commencing 8th November 2021		 Last updated: 
1st October 2021
Odrik 2mg Hard Capsule

PA2010/005/003
 Trandolapril
 Manufacturing delays Date of shortage: 
5th October 2021

Expected return date: 
Late October 2021 		 Last updated: 
28th September 2021
Oramox 125mg/5ml Powder for Oral Suspension

PA0298/019/001
 Amoxicillin
 Unexpected increase in demand  Date of shortage:
22nd October 2021 

Expected return date: 
Unknown at present 		 Last updated: 
19th October 2021 
OxyContin 5mg Prolonged Release Tablets 

PA1688/005/001
  Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021		 Last updated:
12th October 2021
OxyNorm Dispersa 5mg Orodispersible Tablets

PA1688/006/007
 Oxycodone  Unexpected increase in demand  Date of shortage: 
5th October 2021 

Expected return date: 
4th November 2021		 Last updated: 
18th October 2021
OxyNorm Dispersa 10mg Orodispersible Tablets

PA1688/006/008
 Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date:
Unknown at present 		  Last updated: 
12th October 2021
OxyNorm Dispersa 20mg Orodispersible Tablets

PA1688/006/009
 Oxycodone Manufacturing delays  Date of shortage: 
26th October 2021 

Expected return date:
February 2022		 Last updated: 
20th October 2021 
Palexia 4mg/ml Oral Solution

PA2242/012/010 		 Tapentadol hydrochloride  Quality issue

(multiple countries affected) 		 Date of shortage:
15th February 2021

Expected return date:
Unknown at present 		 Last updated: 
22nd February 2021
Paralief 500mg Tablets 

24 pack only

PA0126/020/001
 Paracetamol API unavailability  Date of shortage: 
Week commencing 23rd August 2021

Expected return date: 
27th October 2021
 Last updated: 
28th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w

PA0278/017/002
 Hydrocortisone & Lidocaine Hydrochloride  Manufacturing delays  Date of shortage:
February 2021

Expected return date:
January 2022		 Last updated: 
8th April 2021
Qlaira Film Coated Tablets

PA1410/058/001
  Estradiol API unavailability  Date of shortage: 
Mid November 2021

Expected return date: 
Q2 2022		 Last updated: 
7th October 2021

HCP letter
Questran 4g Powder for Oral Suspension

PA2239/005/001 		 Colestyramine  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2019

Expected return date:
January 2022		 Last updated:
30th March 2021 
Rifater 50mg/300mg/120mg Tablets

PA0822/143/002
 Isoniazid & Pyrazinamide & Rifampicin Quality issue

(multiple countries impacted)		 Date of shortage: 
23rd July 2021

Expected return date: 
26th October 2021		 Last updated:
18th October 2021

AMRIC guidance V3
Rosuvastatin 5mg Film Coated Tablets

PA2315/068/001
 Rosuvastatin Quality issue  Date of shortage:
27th August 2021

Expected return date: 
Q2 2022		  Last updated: 
30th August 2021
Rosuvastatin 10mg Film Coated Tablets

PA2315/068/002
 Rosuvastatin  Quality issue Date of shortage: 
27th August 2021 

Expected return date: 
Q2 2022 		 Last updated: 
30th August 2021 
Rosuvastatin 20mg Film Coated Tablets

PA2315/068/003
 Rosuvastatin   Distribution issue Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 		 Last updated: 
21st October 2021 
Rosuvastatin 40mg Film Coated Tablets

PA2315/068/004
 Rosuvastatin   Distribution issue
 Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
 Last updated: 
21st October 2021 
Sevelamer Carbonate 800mg Film Coated Tablets

PA0577/205/001
 Sevelamer  Manufacturing delays Date of shortage: 
Late October

Expected return date: 
Unknown at present  		 Last updated: 
22nd October 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Mid-December 2021		 Last updated:
22nd October 2021
Stesolid Rectal Solution 5mg

PA2315/137/001
 Diazepam  Manufacturing delays Date of shortage: 
Late August 2021

Expected return date: 
November 2021		 Last updated: 
12th August 2021
Stesolid Rectal Solution 10mg

PA2315/137/002
  Diazepam Manufacturing delays  Date of shortage: 
Week commencing 19th July 2021. 

Expected return date: 
November 2021		 Last updated: 
21st July 2021
Targin 20mg/10mg Prolonged Release Tablets

PA1688/010/001		 Oxycodone & Naloxone  Shipping delays Date of shortage: 
27th September 2021 

Expected return date: 
28th October 2021
 Last updated: 
22nd October 2021
Telmisartan Rowa 40mg Tablets

PA0074/078/002
 Telmisartan  Unexpected increase in demand  Date of shortage: 
7th September 2021

Expected return date: 
Late November 2021		  Last updated: 
20th October 2021
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
 Alendronic acid API unavailability  Date of shortage: 
6th September 2021 

Expected return date: 
Late November 2021 		 Last updated: 
23rd August 2021 
Tracrium 10 mg/ml, Solution for injection or infusion

(25ml ampoule)

PA1691/029/002
 Atracurium  Unexpected increase in demand Date of shortage: 
24th September 2021 

Expected return date: 
20th November 2021 		 Last updated: 
24th September 2021
Trandate 200mg Film Coated Tablet

PA1638/006/003 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
End October 2021		 Last updated:
11th October 2021
TPN – various B. Braun products
 Various  Manufacturing delays  Date of shortage: 
4th October 2021

Expected return date: 
Unknown at present		 Last updated: 
5th October 2021

HCP letter
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment

PA22650/004/001
 Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride  Regulatory issue Date of shortage: 
Late September 2021

Expected return date: 
Late December 2021
 Last updated: 
15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets

PA1688/011/001
Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abstral 100mcg Sublingual Tablets

PA2288/004/002
  Fentanyl  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
3rd September 2021 

Expected return date: 
Week commencing 1st October 2021		 Last updated: 
22nd October 2021
Abstral 200mcg Sublingual Tablets

PA2288/004/003
 Fentanyl Manufacturing delays 

(multiple countries affected)		 Date of shortage:
15th August 2021

Return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 300mcg Sublingual Tablets

PA2288/004/004
 Fentanyl  Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
5th October 2021

Expected return date: 
Week commencing 25th October 2021
 Last updated: 
22nd October 2021
Abstral 400mcg Sublingual Tablets

PA2288/004/005
 Fentanyl  Manufacturing delays 

(multiple countries affected)
 Date of shortage: 
4th October 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Abstral 600mcg Sublingual Tablets

PA2288/004/006
 Fentanyl   Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
2nd September 2021 

Expected return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 700mcg Sublingual Tablets

PA2288/004/007
 Fentanyl Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
2nd September 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Adizem-XL 180mg Prolonged Release Capsules

PA1688/001/005
 Dilitazem  Manufacturing delays Date of shortage: 
1st October 2021

Expected return date: 
November 2021 		 Last updated: 
27th September 2021
Amitriptyline 25mg Film Coated Tablets

PA0126/041/001
 Amitriptyline
 API unavailability Date of shortage: 
2nd September 2021 

Expected return date: 
Late October 2021		 Last updated: 
7th September 2021 

HCP letter
Astilin 10mg Tablets

PA23163/001/001
 Amitriptyline  Awaiting update Date of shortage: 
27th August 2021

Expected return date: 
29th October 2021		 Last updated: 
5th October 2021

HCP letter
Ativan 4mg/ml Solution for Injection

PA0822/090/002 		 Lorazepam  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2020

Expected return date:
Unknown at present		 Last updated:
14th May 2021 
 
HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
2022		 Last updated:
3rd February 2021
Bendroflumethiazide 2.5mg Tablets

PA22749/021/001
 Bendroflumethiazide
  Regulatory issue Date of shortage:
3rd September 2021

Expected return date: 
Awaiting update		 Last updated: 
1st October 2021
Beromun 1mg Powder for Solution for Infusion

EU/1/99/097/001 		 Tasonermin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
December 2020

Expected return date:
November 2021		 Last updated:
1st June 2021
Calcium Acetate 500mg Tablets

PA0281/063/001
 Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
Late December 2021		 Last updated: 
30th September 2021
Canesten HC 1% w/w + 1% w/w Cream

PA1410/040/002
 Clotrimazole & Hydrocortisone  Manufacturing delays Date of shortage: 
30th September 2021 

Expected return date:
5th November 2021		 Last updated: 
22nd September 2021
Catapres Tablets 100mcg

PA2256/003/001
  Clonidine Manufacturing delays

(multiple countries affected)		 Date of shortage: 
25th July 2021

Expected return date: 
25th October 2021		 Last updated: 
21st June 2021 
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution

PA2299/005/001
 Chlorhexidine acetate & cetrimide
 Unexpected increase in demand Date of shortage: 
September 2021 

Expected return date: 
Mid November 2021 		 Last updated: 
20th October 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution

PA0281/124/001 		 Chlorpromazine hydrochloride  Manufacturing delays  Date of shortage:
End of February 2021

Expected return date:
End January 2022		 Last updated:
5th October 2021
 
HCP letter
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes 

PA0540/097/008
 Enoxaparin sodium  API unavailability   Date of shortage: 
22nd October 2021 

Expected return date: 
Unknown at present		 Last updated: 
13th October 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion

PA1457/001/001
 Amoxicillin & Clavulanic acid
 Manufacturing delays Date of shortage: 
13th October 2021 

Expected return date: 
Awaiting update		 Last updated: 
18th October 2021 
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion

PA1457/001/002		 Amoxicillin & clavalunic acid Unexpected increase in demand Date of shortage:
5th February 2020

Expected return date:
Awaiting update
 Last updated:
19th October 2021
CoAprovel 300mg/12.5mg Tablets

EU/1/98/086/004
 Irbesartan & Hydrochlorothiazide  Shipping delay  Date of shortage: 
5th November 2021

Expected return date: 
Late November 2021  		 Last updated: 
22nd October 2021 
Cyklokapron 100 mg/mL Solution for Injection/Infusion

PA0822/117/001
 Tranexamic acid Manufacturing delays Date of shortage: 
Week commencing 18th October 2021

Expected return date: 
Week commencing 15th November 2021 		 Last updated: 
5th October 2021 
Deslor 5mg Film Coated Tablets

PA0711/202/001
 Desloratidine Awaiting information   Date of shortage: 
19th September  2021  

Expected return date: 
Late December 2021		 Last updated: 
October 2021 
Desmopressin 100mcg/ml Nasal Drop Solution

PA1009/001/001 		 Desmopressin  Manufacturing delays due to quality issue

(multiple countries affected) 		 Date of shortage:
Mid December 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Dioralyte Blackcurrant Powder for Oral Solution (20 pack)

PA0540/098/001
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate  Unexpected increase in demand  Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021		 Last updated: 
30th September 2021
Dioralyte Citrus Powder for Oral Solution
(20 pack)

PA0540/098/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution
(6 pack)

PA0540/194/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Doxatan 4mg Tablets

PA0126/202/003 		 Doxazosin  Manufacturing delay   Date of shortage: 
4th October 2021

Expected return date:
Week commencing 1st November 2021		 Last updated: 
20th October 2021
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005		 Phenytoin Manufacturing delays

(multiple countries affected)		 Date of shortage:
Early November 2019

Expected return date:
Unknown at present		 Last updated:
4th June 2020
 
HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion

PA1852/002/001 		 Esomeprazole  Unavailability of API  Date of shortage:
Early October 2020

Expected return date:
Late November 2021		 Last updated:
12th October 2021
Ezetimibe Rowa 10mg Tablets

PA0074/074/001
 Ezetimibe Awaiting information  Date of shortage: 
19th October 2021 

Expected return date: 
Late November 2021 		 Last updated: 
21st October 2021
Ezetimibe Teva 10mg tablets

PA1986/012/001
 Ezetimibe  Quality Issue  Date of shortage: 
18th October 2021 

Expected return date: 
13th December 2021		 Last updated: 
4th October 2021
Ezetimibe 10mg tablets

PA0577/198/001
 Ezetimibe
 Manufacturing delays  Date of shortage: 
Late August 2021 

Expected return date: 
Early November 2021		 Last updated: 
4th October 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets

PA0711/262/001
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 22nd July 2021

Expected return date: 
October 2021		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date: 
End November 2021
 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets

PA1986/067/003
 Ezetimibe & simvastatin
 API unavailability

(multiple countries impacted) 		 Date of shortage: 
30th August 2021 

Expected return date: 
Awaiting update		 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets

PA0126/281/002
Ezetimibe & simvastatin
 Manufacturing delays   Date of shortage: 
Week commencing 20th September 2021

Expected return date: 
Unknown at present		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets

PA0126/281/004
 Ezetimibe & simvastatin
 Manufacturing delays Date of shortage: 
Week commencing 20th September 2021

Expected return date:  
Unknown at present		 Last updated: 
20th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection

PA0822/198/002
 Folinic Acid  Unexpected increase in demand Date of shortage: 
Week commencing 27th September 2021

Expected return date: 
Awaiting update		 Last updated:
18th October 2021
Fomicyt 40mg/ml Powder for Solution for Infusion

PA1972/001/001
 Fosfomycin sodium Regulatory issue  Date of Shortage: 
October 2021 

Expected return date: 
Unknown at present		 Last updated: 
12th October 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension

PA1142/014/001
 Gentamicin & Hydrocortisone Unavailability of API 

(multiple countries affected)		 Date of shortage: 
23rd August 2021

Expected return date:
Late November 2021		 Last updated: 
9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Imodium Plus 2mg/125mg Tablets

PA0330/050/001
 Loperamide & simeticone  Manufacturing delay  Date of shortage: 
11th October 2021 

Expected return date:
Week commencing 22nd November 2021		 Last updated: 
20th October 2021
Innohep 10,000 IU/ml Solution for Injection

PA0046/060/002
 Tinzaparin sodium
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
20th September 2021

Expected return date: 
Mid-November 2021
 Last updated: 
23rd September 2021
Instanyl 50mcg Nasal Spray 

EU/1/09/531/010-013
 Fentanyl  Quality issue 
(multiple countries affected)		 Date of shortage: 
1st August 2021 

Expected return date: 
February 2022
 Last updated: 
20th August 2021
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated: 
20th August 2021
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated:
20th August 2021
Invokana 300mg Film Coated Tablets

EU/1/13/884/005-008		 Canagliflozin
 Unexpected increase in demand  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021 		 Last updated: 
12th October 2021
Letrozole 2.5mg Film Coated Tablets

PA2315/109/001
 Letrozole  Awaiting information   Date of shortage: 
Week commencing 25th October 2021

Expected return date: 
End November 2021		 Last updated: 
18th October 2021 
Letrozole 2.5mg Film Coated Tablets

PA0126/198/001
 Letrozole  Manufacturing delays  Date of shortage: 
22nd October 2021 

Expected return date: 
22nd December 2021		 Last updated: 
18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets

PA0749/085/001
 Letrozole  API unavailability 

(multiple countries affected) 		 Date of shortage: 
Week commencing 9th August 2021

Expected return date: 
January 2021		 Last updated: 
5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet

PA0711/051/002 		 Lisinopril & Hydrochlorothiazide  Manufacturing delays  Date of shortage:
8th September 2020

Expected return date:
Week commencing 1st November 2021		 Last updated:
20th October 2021
Losartan 50mg Tablet 

PA2315/059/002 		 Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
Unknown at present 		 Last updated:
13th April 2021
Losartan 100mg Tablet

PA2315/059/003 		 Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film-Coated Tablets

PA0749/026/001
 Losartan & Hydrochlorothiazide
  Quality issue Date of shortage: Late October 2021  

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets

PA0749/026/002
 Losartan & Hydrochlorothiazide
 Quality issue  Date of shortage: 
Late October 2021

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
Unknown at present 
 Last updated: 
24th September  2021 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Metaraminol 10mg/ml Solution for Injection or Infusion 

PA22893/001/001		 Metaraminol  Awaiting update Date of shortage: 
Early April 2021 

Expected return date:
Awaiting update		 Last updated: 
30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution

PA23081/008/001
 Metformin  Regulatory Issue Date of shortage: 
13th August 2021

Expected return date: 
Unknown at present		 Last updated: 
10th August 2021
Mydrilate 1.0% w/v Eye Drops

PA22709/003/002
 Cyclopentolate Manufacturing delay  Date of shortage:
Early September 2021

Expected return date: 
Mid-October 2021		 Last updated: 
27th September 2021 
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion 

PA0073/111/002
 Naloxone Manufacturing delay  Date of shortage: 
18th October 2021

Expected return date: 
3rd December 2021 		 Last updated: 
19th October 2021
Nanocis 0.24mg Kit for Radiopharmaceutical Preparation

PA0677/006/001
 Rhenium sulphide
 Awaiting information  Date of shortage: 
Week commencing 20th September 2021 

Expected return date: 
Week commencing 8th November 2021		 Last updated: 
1st October 2021
Odrik 2mg Hard Capsule

PA2010/005/003
 Trandolapril
 Manufacturing delays Date of shortage: 
5th October 2021

Expected return date: 
Late October 2021 		 Last updated: 
28th September 2021
Oramox 125mg/5ml Powder for Oral Suspension

PA0298/019/001
 Amoxicillin
 Unexpected increase in demand  Date of shortage:
22nd October 2021 

Expected return date: 
Unknown at present 		 Last updated: 
19th October 2021 
OxyContin 5mg Prolonged Release Tablets 

PA1688/005/001
  Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021		 Last updated:
12th October 2021
OxyNorm Dispersa 5mg Orodispersible Tablets

PA1688/006/007
 Oxycodone  Unexpected increase in demand  Date of shortage: 
5th October 2021 

Expected return date: 
4th November 2021		 Last updated: 
18th October 2021
OxyNorm Dispersa 10mg Orodispersible Tablets

PA1688/006/008
 Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date:
Unknown at present 		  Last updated: 
12th October 2021
OxyNorm Dispersa 20mg Orodispersible Tablets

PA1688/006/009
 Oxycodone Manufacturing delays  Date of shortage: 
26th October 2021 

Expected return date:
February 2022		 Last updated: 
20th October 2021 
Palexia 4mg/ml Oral Solution

PA2242/012/010 		 Tapentadol hydrochloride  Quality issue

(multiple countries affected) 		 Date of shortage:
15th February 2021

Expected return date:
Unknown at present 		 Last updated: 
22nd February 2021
Paralief 500mg Tablets 

24 pack only

PA0126/020/001
 Paracetamol API unavailability  Date of shortage: 
Week commencing 23rd August 2021

Expected return date: 
27th October 2021
 Last updated: 
28th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w

PA0278/017/002
 Hydrocortisone & Lidocaine Hydrochloride  Manufacturing delays  Date of shortage:
February 2021

Expected return date:
January 2022		 Last updated: 
8th April 2021
Qlaira Film Coated Tablets

PA1410/058/001
  Estradiol API unavailability  Date of shortage: 
Mid November 2021

Expected return date: 
Q2 2022		 Last updated: 
7th October 2021

HCP letter
Questran 4g Powder for Oral Suspension

PA2239/005/001 		 Colestyramine  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2019

Expected return date:
January 2022		 Last updated:
30th March 2021 
Rifater 50mg/300mg/120mg Tablets

PA0822/143/002
 Isoniazid & Pyrazinamide & Rifampicin Quality issue

(multiple countries impacted)		 Date of shortage: 
23rd July 2021

Expected return date: 
26th October 2021		 Last updated:
18th October 2021

AMRIC guidance V3
Rosuvastatin 5mg Film Coated Tablets

PA2315/068/001
 Rosuvastatin Quality issue  Date of shortage:
27th August 2021

Expected return date: 
Q2 2022		  Last updated: 
30th August 2021
Rosuvastatin 10mg Film Coated Tablets

PA2315/068/002
 Rosuvastatin  Quality issue Date of shortage: 
27th August 2021 

Expected return date: 
Q2 2022 		 Last updated: 
30th August 2021 
Rosuvastatin 20mg Film Coated Tablets

PA2315/068/003
 Rosuvastatin   Distribution issue Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 		 Last updated: 
21st October 2021 
Rosuvastatin 40mg Film Coated Tablets

PA2315/068/004
 Rosuvastatin   Distribution issue
 Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
 Last updated: 
21st October 2021 
Sevelamer Carbonate 800mg Film Coated Tablets

PA0577/205/001
 Sevelamer  Manufacturing delays Date of shortage: 
Late October

Expected return date: 
Unknown at present  		 Last updated: 
22nd October 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Mid-December 2021		 Last updated:
22nd October 2021
Stesolid Rectal Solution 5mg

PA2315/137/001
 Diazepam  Manufacturing delays Date of shortage: 
Late August 2021

Expected return date: 
November 2021		 Last updated: 
12th August 2021
Stesolid Rectal Solution 10mg

PA2315/137/002
  Diazepam Manufacturing delays  Date of shortage: 
Week commencing 19th July 2021. 

Expected return date: 
November 2021		 Last updated: 
21st July 2021
Targin 20mg/10mg Prolonged Release Tablets

PA1688/010/001		 Oxycodone & Naloxone  Shipping delays Date of shortage: 
27th September 2021 

Expected return date: 
28th October 2021
 Last updated: 
22nd October 2021
Telmisartan Rowa 40mg Tablets

PA0074/078/002
 Telmisartan  Unexpected increase in demand  Date of shortage: 
7th September 2021

Expected return date: 
Late November 2021		  Last updated: 
20th October 2021
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
 Alendronic acid API unavailability  Date of shortage: 
6th September 2021 

Expected return date: 
Late November 2021 		 Last updated: 
23rd August 2021 
Tracrium 10 mg/ml, Solution for injection or infusion

(25ml ampoule)

PA1691/029/002
 Atracurium  Unexpected increase in demand Date of shortage: 
24th September 2021 

Expected return date: 
20th November 2021 		 Last updated: 
24th September 2021
Trandate 200mg Film Coated Tablet

PA1638/006/003 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
End October 2021		 Last updated:
11th October 2021
TPN – various B. Braun products
 Various  Manufacturing delays  Date of shortage: 
4th October 2021

Expected return date: 
Unknown at present		 Last updated: 
5th October 2021

HCP letter
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment

PA22650/004/001
 Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride  Regulatory issue Date of shortage: 
Late September 2021

Expected return date: 
Late December 2021
 Last updated: 
15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets

PA1688/011/001

Date of shortage: 
20th October 2021 

Expected return date: 
Unknown at present

Anapen 300 micrograms in 0.3ml solution for injection in a pre-filled syringe

Cholera vaccine
Cholera vaccine

Sterculia
Frangula

Manufacturing delay


Contact us:

Medicinal Product Shortages Unit
Health Products Regulatory Authority 
Kevin O’Malley House
Earlsfort Terrace,
Dublin 2
Tel: +353 1 676 4971
Fax: +353 1 676 7836
shortages@hpra.ie