My HPRA: Register

Medicinal Product Shortages

The HPRA is responsible for co-ordinating the management of shortages of human medicines on the Irish market. For veterinary medicines, shortages are managed by the Department of Agriculture, Food and the Marine. 

The HPRA works with a variety of stakeholders including manufacturers, wholesale distributors, marketing authorisation holders, healthcare professionals, the Health Service Executive, patients and representative groups to respond to potential shortages and reduce the impact of shortages on patients.

The definition of a shortage is when the supply of a medicinal product is inadequate to meet the needs of the patient. 

The HPRA, in collaboration with stakeholders, has published a framework for a multi-stakeholder approach to handling shortages of human medicinal products. The aim of the framework is to help prevent shortages from occurring and to reduce the impact of shortages on patients by co-ordinating the management of potential or actual shortages as they arise. You can see the shortages case study on Adrenaline auto-injectors (AAIs) as an example of how the framework operates in practice. 


Information on reporting shortages for:

Marketing Authorisation Holders

Please complete the Notification of medicinal product shortage from marketing authorisation holder form and return to  shortages@hpra.ie and to the HSE Corporate Pharmaceutical Unit.

Wholesale Distributors and Manufacturers

Please complete the Report of medicinal product shortage affecting the Irish market from wholesale distributors and manufacturers form and return this form to  shortages@hpra.ie.

Patients and Healthcare Professionals

Please complete the Report of medicinal product shortage affecting the Irish market from patients and healthcare professionals form and return to  shortages@hpra.ie. When completing this form, please include as much information as possible.

Veterinary Medicines

Please contact the Department of Agriculture, Food and the Marine.

 

Current and resolved shortages

The HPRA publishes a list of shortages currently affecting the Irish market that have been notified to us and that may have a medium or high impact on patients. This list can be found below. More information on the impact level can be found in the framework for a multi-stakeholder approach to handling shortages of human medicinal products.

The HPRA maintains a consolidated list of resolved shortages for a period of six months. Details of shortages that have been resolved in the last six months can be found here.


Please use search function below to find relevant product or active ingredient


Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abidec Multivitamin Oral Drops Solution Abidec Multivitamin Oral Drops Solution 

PA1186/001/001
  Various Regulatory issue Date of shortage: 
18th July 2022

Expected return date: 
Unknown at present 		 Last updated: 
19th July 2022 
Abstral 300mcg Sublingual Tablets

PA2288/004/004
 Fentanyl  Unexpected increase in demand  Date of shortage: 
28th July 2022

Expected return date: 
Late September 2022 		 Last updated: 
28th July 2022 
Acetylcysteine Essential-Healthcare 600mg Effervescent Tablets

PA2130/002/001
 Acetylcysteine
 Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
Late December 2021 

Expected return date: 
Awaiting update		 Last updated:
11th July 2022
Acerycal 10mg/10mg Tablets

PA0568/018/004
 Perindopril & amlodipine
 Manufacturing delays  Date of shortage: 
July 2022

Expected return date: 
Week commencing 4th September 2022		 Last updated: 
11th August 2022 
Actilyse Cathflo 2mg Powder for Solution for Injection and Infusion

PA0775/011/001		 Alteplase
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
Week commencing 9th May 2022

Expected return date: 
2024 		 Last updated: 
10th May 2022

HCP letter
Actilyse 50mg Powder and Solvent for Solution for Injection and Infusion

PA0775/011/001
 Alteplase  Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
Week commencing 8th August 2022

Expected return date: 
Week commencing 15th August 		 Last updated: 
11th August 2022 

HCP letter
Aldactone 25mg Film Coated Tablets

PA0822/110/001
  Spironolactone Unexpected increase in demand  Date of shortage: 
Mid August 2022

Expected return date: 
Week commencing 5th September 2022 		 Last updated: 
12th August 2022

HCP letter
Amoxicillin 250mg/5ml Powder for Oral Suspension

PA0126/282/004
 Amoxicillin  Manufacturing delays Date of shortage: 
4th July 2022

Expected return date: 
1st October 2022		 Last updated: 
28th June 2022 
Antabuse 400mg Effervescent Tablets

PA1380/008/001
 Disulfiram
  API unavailability 

(multiple countries affected)		 Date of shortage: 
Week commencing 25th July 2022

Expected return date: 
Week commencing 19th September 2022 		 Last updated: 
11th July 2022 
Apidra Solostar 100 units/ml Solution for Injection in a Pre Filled Pen

EU/1/04/285/032
 Insulin glulisine  Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
23rd August 2022

Expected return date: 
Early September 2022		 Last updated: 
17th August 2022 
Arava 10mg Film Coated Tablets

EU/1/99/118/003
 Leflunomide   API unavailability 

(multiple countries affected)		 Date of shortage: 
End July 2022 

Expected return date: 
End September 2022		 Last updated: 
15th July 2022

HCP letter
Areloger 7.5mg Tablets

PA0577/057/001
  Meloxicam Manufacturing delays
 Date of shortage: 
Mid April 2022

Expected return date: 
August 2022		 Last updated: 
1st April 2022
Areloger 15mg Tablets

PA0577/057/002
  Meloxicam Manufacturing delays  Date of shortage:
End May 2022

Expected return date 
September 2022 		  Last updated: 
27th June 2022
Azromax 250mg Film Coated Tablets

PA0577/122/001
 Azithromycin  Shipment delay Date of shortage: 
24th May 2022

Expected return date: 
Early August 2022		 Last updated: 
8th June 2022
Azithromycin Clonmel 250mg Film Coated Tablets

PA0126/150/001
 Azithromycin  Quality issue 

(multiple countries impacted)		 Date of shortage: 
Week commencing 18th April 2022

Expected return date: 
Mid September 2022		 Last updated: 
26th July 2022
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
2023		 Last updated:
24th January 2022
Calcium Acetate 500mg Tablets

PA0281/063/001
 Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
Unknown at present		 Last updated: 
9th August 2022
Calcipotriol/Betamethasone Rowex 50mcg/g + 0.5mg/g Ointment

PA0711/254/001
 Calcipotriol & betamethasone
 Manufacturing delays  Date of shortage: 
2nd August 2022

Expected return date: 
October 2022 		 Last updated: 
3rd August 2022 
Canesten 500mg Pessary

PA1410/039/009
 Clotrimazole  Unexpected increase in demand Date of shortage; 
End May 2022

Expected return date:
Early October 2022		 Last updated: 
8th July 2022
Cardura 1mg Tablets 

PA0822/192/001		  Doxazosin Unexpected increase in demand  Date of shortage: 
7th June 2022

Expected return date: 
Late August 2022		 Last updated: 
21st July 2022
Calvepen 333mg Tablets

PA0126/137/001
  Phenoxymethylpenicillin
 Manufacturing delays Date of shortage: 
4th July 2022

Expected return date:
Awaiting update		 Last updated: 
17th August 2022
Calvepen 666mg Tablets

PA0126/137/002
  Phenoxymethylpenicillin
 Manufacturing delays Date of shortage: 
4th July 2022

Expected return date:
Awaiting update		 Last updated: 
17th August 2022
Cefotaxime 1g Powder for solution for injection or infusion

PA0281/223/002 
 Cefotaxime Manufacturing delays  Date of shortage: 
30th November 2021 

Expected return date: 
Unknown at present 
 Last updated: 
17th June 2022
Ceftriaxone 1g Powder for solution for injection or infusion

PA0281/225/001
 Ceftriaxone
 Manufacturing delays  Date of shortage: 
Early August 2022

Expected return date: 
End August 2022 		 Last updated: 
18th July 2022 
Centrax 10mg Tablets

PA0822/010/001
 Prazepam
 Quality issue

(multiple countries affected) 		 Date of shortage: 
End June 2022 

Expected return date: 
Unknown at present		 Last updated: 
13th July 2022 
Cetrotide Powder and Solvent for Solution for Injection

EU/1/99/100/001
  Cetrotide Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
Week commencing 4th July 2022

Expected return date:
Early August 2022		 Last updated: 
23rd June 2022

HCP Letter
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Clonfolic 0.4mg Film Coated Tablets

PA0126/095/001
  Folic Acid API unavailability Date of shortage: 
3rd March 2022

Expected return date: 
23rd November 2022		 Last updated:
8th July 2022
Cozaar 12.5mg Film Coated Tablets

PA23198/002/001		 Losartan Unexpected increase in demand  Date of shortage: 
25th July 2022

Expected return date: 
Late August 2022 		 Last updated: 
25th July 2022 
Cosartal Plus 50mg/12.5mg Film Coated Tablets

PA2315/190/001
 Losartan & hydrochlorothiazide
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Early February 2022

Expected return date: 
Awaiting update 
 Last updated: 
1st July 2022
Cosartal Plus 100mg/25mg Film Coated Tablets

PA2315/190/002
 Losartan & hydrochlorothiazide
  Quality issue

(multiple countries affected)		 Date of shortage: 
Early February 2022 

Expected return date: 
Awaiting update		 Last updated: 
1st July 2022
Creon 25000 Gastro-Resistant Capsules

PA2010/008/002
 Pancreas powder  Shipping delay Date of shortage: 
22nd August 2022

Expected return date:
End August 2022		 Last updated: :
16th August 2022
Creon 10000 Gastro-Resistant Capsules

PA2010/008/001
 Pancreas powder  Shipping delay  Date of shortage: 
26th August 2022

Expected return date: 
End August 2022 		 Last updated: 
16th August 2022 
Dalmane 15mg Hard Capsules

PA2010/039/001
 Flurazepam  Regulatory issue Date of shortage: 
18th June 2022

Expected return date: 
Awaiting update		 Last updated: 
30th June 2022 
Deslor 0.5 mg/ml Oral Solution

PA0711/202/002
 Desloratidine Quality issue Date of shortage: 
17th May 2022

Expected return date: 
Awaiting update		 Last updated: 
2nd August 2022
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
Late 2023		 Last updated:
9th February 2022 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Difflam Spray, 0.15% w/v, Oromucosal Spray

PA2010/030/003
 Benzydamine
 Manufacturing delays Date of shortage: 
Early August 2022

Expected return date: 
Early September 2022 		 Last updated: 
18th July 2022 
Dioralyte Citrus Powder for Oral Solution
(20 pack)

PA0540/098/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
Awaiting update
 Last updated: 
29th April 2022
Doxatan XL 4 mg Prolonged Release Tablets

PA0126/202/004
 Doxazosin  Unexpected increase in demand  Date of shortage: 
20th May 2022

Expected return date: 
18th August 2022		 Last updated: 
16th August 2022
Easofen 200mg Film Coated Tablets 

PA0126/060/001
  Ibuprofen API delays

(multiple countries affected) 		 Date of shortage: 
Week commencing 20th June 2022

Expected return date: 
September 2022		 Last updated: 
16th June 2022
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emtricitabine/Tenofovir disoproxil Accordpharma 200mg/245mg Film Coated Tablets

PA2315/200/002
 Emtricitabine & Tenofovir  Manufacturing delays Date of shortage: 
24th May 2022

Expected return date: 
October 2022		 Last updated: 
5th August 2022
Emtricitabine/Tenofovir disoproxil Mylan 200 mg/245 mg Film Coated Tablets

EU/1/16/1133/001-009
 Emtricitabine & Tenofovir 
 Manufacturing delays Date of shortage:
Week commencing 13th June 2022

Expected return date:
Late September 2022		 Last updated: 
8th August 2022
Estradot 37.5mcg/24 hours, Transdermal Patch

PA0896/010/001
  Estradiol Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
Mid February 2022 

Expected return date: 
Mid October 2022		 Last updated: 
12th July 2022

HSE guidance

HCP letter
Estradot 50mcg/24 hours, Transdermal Patch

PA0896/010/002
  Estradiol Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
Early February 2022

Expected return date: 
Mid October 2022		 Last updated: 
12th July 2022

HSE guidance

HCP letter
Estradot 75mcg/24 hours, Transdermal Patch

PA0896/010/003
  Estradiol Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
26th February 2022

Expected return date: 
Mid September 2022
Last updated: 
12th July 2022

HSE guidance

HCP letter
Estradot 100mcg Transdermal Patch

PA0896/010/004
  Estradiol Unexpected increase in demand

(multiple countries affected)		 Date of shortage:
22nd February 2022

Expected return date: 
Mid August		 Last updated: 
12th July 2022

HSE guidance

HCP letter
Eumovate Cream 0.05% 

PA1077/006/001		  Clobetasone butyrate Manufacturing delays

(multiple countries affected)		 Date of shortage: 
20th June 2022

Expected return date: 
Awaiting update		 Last updated:
2nd August 2022
Evorel 50mcg Transdermal Patch

PA22668/008/001
  Estradiol Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
Week commencing 8th August 2022

Expected return date: 
Late September 2022		 Last updated: 
16th August 2022 

HSE guidance
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date:
Unknown at present		 Last updated: 
15th June 2022
Ezetimibe/Simvastatin 10mg/80mg Tablets

PA0577/180/003
 Ezetimibe & Simvastatin
 Unexpected increase in demand   Date of shortage: 
11th November 2021 

Expected return date: 
Unknown at present		 Last updated: 
4th May 2022
Fentanyl 50mcg/ml Solution for Injection

(2ml presentation only)

PA2165/011/001
 Fentanyl Unexpected increase in demand   Date of shortage: 
Week commencing 8th August 2022

Expected return date: 
Week commencing 15th August 2022		 Last updated: 
9th August 2022
Fentanyl 100mcg in 2 ml Solution for Injection Fentanyl Regulatory issue Date of shortage: 
1st July 2022 

Expected return date: 
26th August 2022
 Last updated: 
9th August 2022
Fentanyl 500mcg in 10ml Solution for Injection Fentanyl  Regulatory issue  Date of shortage: 
8th July 2022 

Expected return date: 
Unknown at present
 Last updated: 
9th August 2022
Fexofenadine Hydrochloride 120mg Film Coated Tablets

PA22871/004/002
  Fexofenadine Unexpected increase in demand  Date of shortage: 
11th January 2022 

Expected return date: 
Week commencing 29th August 2022		 Last updated: 
17th August 2022
Flucloxacillin 1g Powder for Solution for Injection or Infusion

PA0281/122/003		 flucloxacillin
 Manufacturing delays Date of shortage: 
Week commencing 11th July 2022

Expected return date: 
Unknown at present		  Last updated: 
28th June 2022
Fluorouracil 25mg/ml Solution for Injection or Infusion

(100ml presentation only)

PA0822/223/001
 Fluorouracil  Quality issue Date of shortage:
25th February 2022

Expected return date: 
November 2022		 Last updated: 
10th June 2022

HCP letter
Frovex 2.5mg Film Coated Tablets

PA0865/009/001
  Frovatriptan Quality issue

(multiple countries affected)		 Date of shortage: 
11th January 2022 

Expected return date: 
September 2023		  Last updated:
2nd June 2022
Fucibet 20 mg/g + 1 mg/g Cream

(30g presentation)

PA0046/040/001
 Betamethasone & fusidic acid
 Unexpected increase in demand Date of shortage: 
21st June 2022

Expected return date: 
Mid September 2022		 Last updated: 
4th August 2022
Fucibet Lipid 20mg/g + 1mg/g Cream

PA0046/040/002
 Betamethasone & fusidic acid
  Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
27th July 2022

Expected return date: 
7th September 2022		 Last updated: 
4th August 2022
Fucidin 20mg/g Cream

PA0046/004/012
 Fusidic acid
 Manufacturing delays 

(multiple countries affected) 		 Date of shortage:
15th August 2022

Expected return date: 
End August 2022 		 Last updated: 
16th August 2022
Fucidin H 20mg/g + 10mg/g Cream

PA0046/005/005
 Hydrocortisone acetate & fusidic acid Unexpected increase in demand  Date of shortage: 
8th July 2022

Expected return date: 
7th September 2022
 Last updated: 
4th August 2022
Fungizone 50 mg Powder for sterile concentrate

PA2239/004/001
 Amphotericin
Manufacturing delays		 Date of shortage: 
4th July 2022 

Expected return date: 
September 2022
 Last updated: 
3rd August 2022 2022
Gentamicin 40mgml Solution for Injection or Infusion

PA0281/242/002
 Gentamicin  Manufacturing delays Date of shortage: Week commencing 20th December 2021 

Expected return date: 
Awaiting update		 Last updated: 
18th July 2022
Gerax 250mcg Tablets

PA1445/024/001
  Alprazolam Manufacturing delays Date of shortage: 
Mid November 2021

Expected return date: 
Awaiting update		 Last updated: 
2nd August 2022
Glycerol Suppositories BP for Adults

PA0549/028/003
  Glycerol  Manufacturing delays Date of shortage: 
6th June 2022

Expected return date: 
End October 2022		 Last updated: 
10th August 2022
Gyno-Pevaryl Once 150 mg Vaginal Pessary

PA22650/006/001
 Econazole nitrate
 Manufacturing delays  Date of shortage: 
March 2022

Expected return date: 
Unknown at present 		 Last updated: 
9th March 2022 
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
Unknown at present 		 Last updated:
25th July 2022
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
Unknown at present		 Last updated:
25th July 2022
Ibandronic Acid Mylan 150mg Film coated Tablets

PA0577/111/001
 Ibandronic Acid API unavailability  Date of shortage: 
8th August 2022

Expected return date: 
Early October 2022 		 Last updated:
9th August 2022 
Instanyl 50mcg Nasal Spray 

EU/1/09/531/010-013
 Fentanyl  Quality issue 
(multiple countries affected)		 Date of shortage: 
1st August 2021 

Expected return date: 
End September 2022		 Last updated: 
15th July 2022
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
End February 2023		 Last updated: 15th July 2022
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
End February 2023		 Last updated:
15th July 2022
Irinotecan Hydrochloride 20 mg/ml concentrate for solution for infusion

(100mg/5ml strength only)

PA1986/068/001
 Irinotecan hydrochloride trihydrate  Manufacturing delays

(multiple countries affected)		 Date of shortage: 
Early February 2022

Expected return date: 
Mid August 2022		 Last updated:
17th June 2022
Kentera Transdermal Patch

EU/1/03/270/1-2
 Oxybutin Manufacturing delays 

(Multiple countries affected)		 Date of shortage: 
Week commencing 1st August 2022

Expected return date: 
Week commencing 29th August 2022		 Last updated: 
2nd August 2022 
Kopen 250mg Tablets

PA0298/007/001
 Phenoxymethylpenicillin 
 Unexpected increase in demand Date of shortage: 
Late April 2022

Expected return date: 
Awaiting update		 Last updated:
18th August 2022
Kopen Sugar Free 125mg/5ml Powder for Oral Solution

PA0298/007/002
 Phenoxymethylpenicillin 
 Unexpected increase in demand  Date of shortage: 
1st April 2022

Expected return date:
Awaiting update		 Last updated:
18th August 2022
Kopen Sugar Free 250mg/5ml Powder for Oral Solution

PA0298/007/003
 Phenoxymethylpenicillin 
 Unexpected increase in demand Date of shortage: 
1st April 2022

Expected return date: 
Awaiting update		 Last updated: 
18th August 2022
Lercanidipine Clonmel 20mg Tablets

PA0126/187/002
 Lercanidipine API unavailability   Date of shortage: 
End July 2022

Expected return date:
Early October 2022		 Last updated: 
18th July 2022 
Levobupivacaine 1.25mg/ml Solution for Infusion

A2059/009/002
 Levobupivacaine API unavailability  

(multiple countries affected)		 Date of shortage: 
Week commencing 29th August 2022

Expected return date: 
8th September 2022		 Last updated:
18th August 2022
Levobupivacaine 2.5mg/ml Solution for Injection/Infusion

PA2059/009/003
  Levobupivacaine API unavailability

(multiple countries affected)		 Date of shortage: 
Week commencing 29th August 2022

Expected return date: 
November 2022		 Last updated: 
18th August 2022
Levobupivacaine 5mg/ml Solution for Injection/Infusion

A2059/009/004
  Levobupivacaine API unavailability

(multiple countries affected)
 Date of shortage: 
Week commencing 5th September 2022

Expected return date: 
November 2022 		 Last updated: 
18th August 2022 
Loniten 5mg Tablets

PA0822/130/001
 Minoxidil
 Manufacturing delays Date of shortage: 
Early August 2022

Expected return date: 
Week commencing 15th August 2022		 Last updated: 
5th August 2022
Lyclear 5% w/w Dermal Cream

PA1077/066/001		  Permethrin Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
Week commencing 11th July 2022

Expected return date: 
January 2023		 Last updated: 
27th June 2022
Lyrica 25mg Hard Capsules

EU/1/04/279/003-4
  Pregabalin Capacity constraints Date of shortage: 
Week commencing 20th June 2022

Expected return date: 
Early September 2022
 Last updated: 
5th August 2022
Lyrica 25mg Hard Capsules

EU/1/04/279/003
 Pregabalin Capacity constraints
 Date of shortage: 
Week commencing 15th July 2022

Expected return date: 
Early September 2022
 Last updated: 
12th August 2022
Lyrica 75mg Hard Capsules 

EU/1/04/279/012
 Pregabalin Capacity constraints  Date of shortage: 
12th August 2022

Expected return date: 
Late September 2022 		 Last updated: 
15th August 2022 
Lyrica 200mg Hard Capsules

EU/1/04/279/021
 Pregabalin Capacity constraints  Date of shortage: 
18th July 2022

Expected return date: 
Late September 2022		 Last updated: 
12th August 2022 
Marcain 0.25% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/001
 Bupivacaine & adrenaline Manufacturing delays 

(multiple countries affected)		 Date of shortage:
Early June 2022

Expected return date: 
17th October 2022		 Last updated: 
12th August 2022
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
Late January 2022
 Last updated: 
12th August 2022 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Melfen 200mg Film Coated Tablets

PA0126/012/001
 Ibuprofen
  Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
Early August 2022

Expected return date: 
Late September 2022		 Last updated: 
18th July 2022 
Melfen 400mg Film Coated Tablets

PA0126/012/002		 Ibuprofen API delays

(multiple countries affected)		 Date of shortage: 
20th May 2022

Expected return date: 
End September 2022		 Last updated: 
25th July 2022
Metalyse 50mg Powder and Solvent for Solution for Injection

EU/1/00/169/006
Tenecteplase		 Manufacturing delays

(multiple countries affected) 		 Date of shortage: 
29th July 2022 2022

Expected return date: 
2023		 Last updated: 
2nd August 2022
Midazolam 5mg/ml Solution for Injection or Infusion 

PA2315/063/006
 Midazolam Regulatory issue  Date of shortage: 
2nd August 2022

Expected return date: 
Week commencing 15th August 2022 		 Last updated: 
3rd August 2022 
Minims Artificial Tears 0.35% w/w + 0.44% w/w Eye Drops, Solution

PA22698/009/001
 Sodium chloride & hydroxyethylcellulose
 Quality issue  Date of shortage:
April 2022

Expected return date: 
Week commencing 10th October 2022 		 Last updated: 
8th August 2022
Miochol-E 20mg Powder and Solvent for Instillation Solution for Inraocular Use 

PA1245/002/001
 Acetylcholine   API  unavailability 

(multiple countries affected)		 Date of shortage: 
20th March 2022

Expected return date: 
Awaiting update		 Last updated: 
15th July 2022
Mivacron 2mg/ml Solution for Injection

PA1691/031/001 
 Mivacurium chloride
 Manufacturing delays Date of shortage: 
20th June 2022

Expected return date: 
10th December 2022 		 Last updated: 
1st July 2022
Molipaxin 50mg Hard Capsules 

PA540/056/001
 Trazodone Manufacturing delays  Date of shortage: 
20th April 2022

Expected return date: 
End September 2022		 Last updated: 
30th May 2022

HCP letter
Molipaxin 100mg Hard Capsules 

PA540/056/002
  Trazodone
 Manufacturing delays Date of shortage: 
20th June 2022

Expected return date: 
End September 2022		 Last updated: 
10th June 2022 

HCP letter
Morphine Sulphate 10mg/ml Solution for Injection

PA0073/020/001
 Morphine   Manufacturing delays Date of shortage: 
25th July 2022

Expected return date: 
Awaiting update		 Last updated: 
15th August 2022
MST Continus 5mg Prolonged Release Tablets  

PA1688/004/001
 Morphine sulfate
 Manufacturing delays

(multiple countries affected)		 Date of shortage: 
Week commencing 27th June 2022

Expected return date: 
Week commencing 15th August 2022		 Last updated: 
21st July 2022
Nasacort 55mcg/dose Nasal Spray, Suspension

PA23180/001/001
 Triamcinolone
 Quality issue 

(multiple countries impacted)		 Date of shortage:
1st April 2022

Expected return date: 
Awaiting update		 Last updated: 
15th August 2022
Nasofan Aqueous 50mcg Nasal Spray Suspension

PA1986/084/001
  Fluticasone propionate API unavailability  Date of shortage: 
Week commencing 29th August 2022

Expected return date: 
Week commencing 17th October 2022 		 Last updated:
15th August 2022 
Nozinan 25mg/ml Solution for Injection/Infusion

PA0540/115/001
 Levomepromazine Manufacturing delays Date of shortage: 
Week commencing 6th June 2022

Expected return date: 
Awaiting update		 Last updated: 
2nd August 2022 

HSE guidance

HCP letter
Opticrom Allergy Single Dose 2% w/v Eye Drops, Solution

PA23180/010/003
 Sodium cromoglicate
 Quality issue

(multiple countries affected)		 Date of shortage: 
27th January 2022 

Expected return date:
August 2022		 Last updated: 
24th May 2022
Osteomel Once Weekly 70mg Tablets

PA0126/148/002
 Alendronic acid
  Shipping delay Date of shortage: 18th July 2022

Expected return date: 
21st September 2022 		 Last updated: 
11th July 2022 
Oxycodone hydrochloride 50mg/ml Solution for Injection or Infusion

PA0281/235/002
 Oxycodone  Manufacturing delays   Date of shortage: 
1st November 2021 

Expected return date: 
August 2022		 Last updated: 
30th June 2022
Ozempic 0.25mg Solution for Injection in Pre-Filled Pen

EU/1/17/1251/002
 Semaglutide
 Unexpected increase in demand 

(multiple countries impacted)		 Date of shortage: 
15th July 2022

Expected return date: 
September 2022		 Last updated: 
22nd July 2022 

HCP letter
Palladone SR 8mg Prolonged Release Capsules

PA1688/007/009		 Hydromorphone Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
14th June 2022

Expected return date: 
October 2022		 Last updated: 
31st May 2022 
Palexia 75mg Film Coated Tablets

(56 pack presentation) 

PA2242/012/002
 Tapentadol
 Manufacturing delays

(multiple countries affected)		 Date of shortage: 
8th August 2022

Expected return date: 
20th September 2022		 Last updated: 
5th August 2022
Palexia 100mg Film Coated Tablets

PA2242/012/003
 Tapentadol  Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
1st June 2022

Expected return date: 
20th September 2022		 Last updated:
4th August 2022
Palexia 20mg/ml Oral Solution

PA2242/012/011 		 Tapentadol  Quality issue

(multiple countries affected) 		 Date of shortage:
15th February 2021

Expected return date:
October 2022		 Last updated: 
21st April 2022
Palladone 1.3mg Capsules

PA1688/007/001
  Hydromorphone Manufacturing delays Date of shortage:
Week commencing 8th August 2022

Expected return date: 
November 2022		 Last updated: 
28th July 2022 
Paracetamol 500mg Tablets 

(24 pack only)

PA2315/065/003
  Paracetamol Unexpected increase in demand Date of shortage: 
24th May 2022 

Expected return date:
September 2022		 Last updated: 
12th August 2022
Paralief 500mg Tablets

(100 pack only)

PA0126/020/001 
  Paracetamol API unavailability   Date of shortage: 
Mid August 2022

Expected return date:
Late September 2022		 Last updated: 
10th August 2022 
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w

PA0278/017/002
 Hydrocortisone & Lidocaine Hydrochloride  Manufacturing delays  Date of shortage:
February 2021

Expected return date:
Unknown at present 		 Last updated: 
31st January 2022
Praxilene 100mg Capsules

PA2286/003/001
 Naftidrofuryl hydrogen oxalate  API unavailability

(multiple countries affected)		 Date of shortage: 
Mid August 2022

Expected return date: 
January 2023 		 Last updated: 
10th August 2022
Prednisolone 1mg Tablets

PA0126/027/002
 Prednisolone Manufacturing delays  Date of shortage: 
13th July 2022

Expected return date: 
9th September 2022		 Last updated: 
25th July 2022
Prednisolone 5mg Tablets

PA0126/027/001
 Prednisolone  Manufacturing delays  Date of shortage: 
13th July 2022

Expected return date: 
Late September 2022
 Last updated: 
15th July 2022
Pregabalin Sandoz 25mg Tablets 

EU/1/15/1011/003,5
  Pregabalin  Manufacturing delays  Date of shortage: 
2nd August 2022

Expected return date: 
October 2022 		 Last updated:
11th August 2022 
Pregabalin Sandoz 50mg Tablets

EU/1/15/1011/021
 Pregabalin  Manufacturing delays  Date of shortage: 
2nd August 2022

Expected return date: 
October 2022  		 Last updated: 
15th August 2022
Pregabalin Sandoz 75mg Tablets  

EU/1/15/1011/021
 Pregabalin  Manufacturing delays Date of shortage: 
2nd August 2022

Expected return date: 
October 2022 		 Last updated: 
15th August 2022
Pregabalin Sandoz 150mg Tablets 

EU/1/15/1011/045
 Pregabalin  Manufacturing delays  Date of shortage: 
2nd August 2022

Expected return date: 
October 2022 		 Last updated: 
15th August 2022 
Rapifen 500mcg/ml Solution for Injection or Infusion

PA22583/001/001
  Alfentanil   Quality issue  Date of shortage: 
15th July 2022

Expected return date: 
Unknown at present		 Last updated: 
15th July 2022 
Relestat, 0.5mg/ml, Eye Drops, Solution

PA1824/018/001
 Epinastine 
 Unexpected increase in demand 

(multiple countries affected) 		 Date of shortage:
11th July 2022

Expected return date: 
29th August 2922		 Last updated: 
26th July 2022
Rifater 50mg/300mg/120mg Tablets

PA0540/067/001
 Isoniazid, pyrazinamide & rifampicin
 Manufacturing delays  Date of shortage: 
10th August 2022

Expected return date: 
22nd August 2022 		 Last updated: 
11th August 2022 
Risonate Once Weekly 35mg Film Coated Tablets

PA0749/064/001
 Risedronate sodium    API unavailability 

(multiple countries affected)		 Date of shortage: 
Week commencing 27th June 2022

Expected return date: 
Week commencing 26th December 2022		 Last updated: 
13th June 2022 
Rivotril 0.5mg Tablets

PA2239/020/001
 Clonazepam  Manufacturing delays  Date of shortage: 
12th August 2022

Expected return date: 
Mid September 2022 		 Last updated:
17th August 2022 
Rotarix

EU/1/05/330/010
 Human rotavirus, live attenuated
 Manufacturing delays  Date of shortage: 
Week commencing 18th July 2022

Expected return date: 
October 2022		  Last updated: 
11th July 2022 
Six Plus Parapaed Paracetamol Oral Suspension 250mg/5ml

PA0281/002/003
 Paracetamol Quality issue Date of shortage: 
January 2022 

Expected return date:
October 2022		 Last updated: 
14th March 2022
Skinoren 15% Gel

PA1025/009/001
 Azelaic acid
 Manufacturing delays Date of shortage: 
11th August 2022

Expected return date: 
October 2022		 Last updated: 
12th August 2022 
Somavert 15mg Powder and Solvent for Solution for Injection

EU/1/02/240/002
 Pegvisomant
 Unexpected increase in demand Date of shortage: 
Mid August 2022

Expected return date: 
Late September 2022 		 Last updated: 
11th August 2022 
Spironolactone 25mg Film Coated Tablets

PA2315/119/001
  Spironolactone Shipping delay Date of shortage: 
25th April 2022

Expected return date:
Early September 2022		 Last updated: 
5th August 2022
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
25th July 2022
Stemetil 12.5mg/ml Solution for Injection

PA0540/127/002 
 Prochlorperazine mesilate   Manufacturing delays 

(multiple countries affected)		 Date of shortage: 
24th August 2022

Expected return date: 
Late September 2022 		 Last updated: 
17th August 2022 
Sublimaze 50mcg/ml, Solution for Injection

PA22583/002/001
 Fentanyl  Unexpected increase in demand   Date of shortage: 
Early August 2022

Expected return date: 
Unknown at present		 Last updated: 
9th August 2022 
Suboxone 2 mg/0.5mg Sublingual Tablet

EU/1/06/359/002
 Naloxone & Buprenorphine  Unexpected increase in demand Date of shortage: 
April 2022

Expected return date: 
October 2022		 Last updated: 
16th March 2022 
Suboxone 8mg/2mg Sublingual Tablet

EU/1/06/359/004
 Naloxone & Buprenorphine  Unexpected increase in demand   Date of shortage: 
April 2022

Expected return date: 
October 2022 		 Last updated:
16th March 2022
Symbicort Turbohaler 200mcg/6mcg, Inhalation Powder

PPA1463/051/001
 Budesonide & formoterol fumarate dihydrate
  Distribution issue Date of shortage: 
9th August 2022 

Expected return date: 
Unknown at present		 Last updated: 
17th August 2022 
Tamox 10mg Film Coated Tablets

PA0711/022/001
 Tamoxifen Manufacturing delays  Date of shortage: 
Late February 2022

Expected return date: 
September 2022		 Last updated: 
31st May 2022
Targocid 200mg Powder and Solvent for Solution for Injection/Infusion or Oral Solution

PA0540/021/001
 Teicoplanin
  Quality issue 

(multiple countries affected)		 Date of shortage: 
Early August 2022

Expected return date:
Unknown at present 		 Last updated:
18th July 2022
Targocid 400mg Powder and Solvent for Solution for Injection/Infusion or Oral Solution

PA0540/021/002
 Teicoplanin
 Quality issue

(multiple countries affected)		 Date of shortage: 
Early July 2022

Expected return date: 
Late August 2022 		 Last updated: 
1st July 2022 
Tavanic 5 mg/ml Solution for Infusion

PA0540/077/001
 Levofloxacin Unexpected increase in demand  Date of shortage: 
29th June 2022

Expected return date: 
Late August 2022		 Last updated; 
15th August 2022
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
 Alendronic acid  Manufacturing delays

(multiple countries affected) 		 Date of shortage: 
Week commencing 4th April 2022 

Expected return date: 
Early September 2022		 Last updated: 
9th August 2922
Tipol 125mg Suppository

PA0126/331/002
 Paracetamol  Unexpected increase in demand  Date of shortage: 
9th May 2022

Expected return date: 
Unknown at present		 Last updated: 
10th August 2022
Tobi 300mg/5ml Nebuliser Solution

PA2010/063/001
 Tobramycin Manufacturing delays  Date of shortage: 
11th April 2022

Expected return date:
Week commencing 15th August 2022		 Last updated: 
5th August 2022
Toviaz 8mg Prolonged-Release Tablets

EU/1/07/386/008
 Fesoterodine  Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
Week commencing 8th August 2022

Expected return date: 
Week commencing 19th September 2022		 Last updated:
16th August 2022
Tramadol Krka 50mg hard Capsules

PA1347/079/001
 Tramadol  Awaiting information Date of shortage: 
Early August 2022 

Expected return date: 
September 2022		 Last updated: 
9th August 2022 
Tramadol Hydrochloride 50mg Hard Capsules

PA2315/214/001
 Tramadol Manufacturing delays  Date of shortage: 
Late June 2022 

Expected return date: 
Late August 2022		 Last updated: 
4th August 2022 
Tradol 50mg Hard Capsules

PA0711/029/001
 Tramadol 
 Manufacturing delays
 Date of shortage: 
21st June 2022

Expected return date:
Awaiting update		 Last updated:
2nd August 2022
Tuberculin PPD RT23 AJV 2 T.U./0.1 mL, Solution for Injection

PA2160/004/001
 Tuberculin ppd  Manufacturing delays  Date of shortage: 
1st August 2022

Expected return date: 
Early September 2022 		 Last updated: 
10th August 2022 
Tylex 30mg/500mg Hard Capsules

PA0891/014/001
 Codeine and paracetamol  API unavailability   Date of shortage: 
27th July 2022

Expected return date:
August 2022		 Last updated: 
28th July 2022 
Voriconazole 200mg Powder for Solution for Infusion

PA2059/020/001
  Voriconazole Unexpected increase in demand 

(multiple countries affected)		 Date of shortage: 
Week commencing 29th November 2021 

Expected return date: 
Q4 2022		 Last updated: 
22nd February 2022
Warfant 5mg Tablets

PA0073/139/003
 Warfarin   API unavailability   Date of shortage: 
22nd August 2022

Expected return date: 
Unknown at present		 Last update:
8th August 2022 
Zofran 4mg/5ml Syrup

PA0896/036/003
 Ondansetron  Regulatory issue

(multiple countries affected)		 Date of shortage:
Late February 2022

Expected return date:
Week commencing 22nd August 2022		 Last updated: 
17th August 2022

HCP letter
Zydol 50mg Hard Capsules

PA2242/005/001
 Tramadol Unexpected increase in demand Date of shortage: 
Late July 2022

Expected return date: 
16th November 2022 		 Last updated: 
9th August 2022 
Xomolix 2.5mg/ml Solution for Injection

PA2288/003/002
 Droperidol  Quality issue

(multiple countries affected)		 Date of shortage: 
29th May 2021

Expected return date: 
Unknown at present  		 Last updated: 
2nd July 2021
Xylocaine 2% with Adrenaline (Epinephrine) (1:200,000) Solution for Injection

PA1691/027/001
 Lidocaine and adrenaline Manufacturing delay 

(multiple countries impacted)		 Date of shortage: 
2nd February 2022

Expected return date: 
Late December 2022		 Last updated: 
12th August 2022

Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL
Menveo (EU/1/10/614/003) Meningococcal Group A, C, W135 and Y conjugate vaccine PIL



Date of shortage: 
2nd July 2021

Expected return date: 
Unknown at present  
Date of shortage: 
2nd July 2021

Expected return date: 
Unknown at present  

Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 

Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abstral 100mcg Sublingual Tablets

PA2288/004/002
  Fentanyl  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
3rd September 2021 

Expected return date: 
Week commencing 1st October 2021		 Last updated: 
22nd October 2021
Abstral 200mcg Sublingual Tablets

PA2288/004/003
 Fentanyl Manufacturing delays 

(multiple countries affected)		 Date of shortage:
15th August 2021

Return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 300mcg Sublingual Tablets

PA2288/004/004
 Fentanyl  Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
5th October 2021

Expected return date: 
Week commencing 25th October 2021
 Last updated: 
22nd October 2021
Abstral 400mcg Sublingual Tablets

PA2288/004/005
 Fentanyl  Manufacturing delays 

(multiple countries affected)
 Date of shortage: 
4th October 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Abstral 600mcg Sublingual Tablets

PA2288/004/006
 Fentanyl   Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
2nd September 2021 

Expected return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 700mcg Sublingual Tablets

PA2288/004/007
 Fentanyl Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
2nd September 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Adizem-XL 180mg Prolonged Release Capsules

PA1688/001/005
 Dilitazem  Manufacturing delays Date of shortage: 
1st October 2021

Expected return date: 
November 2021 		 Last updated: 
27th September 2021
Amitriptyline 25mg Film Coated Tablets

PA0126/041/001
 Amitriptyline
 API unavailability Date of shortage: 
2nd September 2021 

Expected return date: 
Late October 2021		 Last updated: 
7th September 2021 

HCP letter
Astilin 10mg Tablets

PA23163/001/001
 Amitriptyline  Awaiting update Date of shortage: 
27th August 2021

Expected return date: 
29th October 2021		 Last updated: 
5th October 2021

HCP letter
Ativan 4mg/ml Solution for Injection

PA0822/090/002 		 Lorazepam  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2020

Expected return date:
Unknown at present		 Last updated:
14th May 2021 
 
HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
2022		 Last updated:
3rd February 2021
Bendroflumethiazide 2.5mg Tablets

PA22749/021/001
 Bendroflumethiazide
  Regulatory issue Date of shortage:
3rd September 2021

Expected return date: 
Awaiting update		 Last updated: 
1st October 2021
Beromun 1mg Powder for Solution for Infusion

EU/1/99/097/001 		 Tasonermin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
December 2020

Expected return date:
November 2021		 Last updated:
1st June 2021
Calcium Acetate 500mg Tablets

PA0281/063/001
 Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
Late December 2021		 Last updated: 
30th September 2021
Canesten HC 1% w/w + 1% w/w Cream

PA1410/040/002
 Clotrimazole & Hydrocortisone  Manufacturing delays Date of shortage: 
30th September 2021 

Expected return date:
5th November 2021		 Last updated: 
22nd September 2021
Catapres Tablets 100mcg

PA2256/003/001
  Clonidine Manufacturing delays

(multiple countries affected)		 Date of shortage: 
25th July 2021

Expected return date: 
25th October 2021		 Last updated: 
21st June 2021 
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution

PA2299/005/001
 Chlorhexidine acetate & cetrimide
 Unexpected increase in demand Date of shortage: 
September 2021 

Expected return date: 
Mid November 2021 		 Last updated: 
20th October 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution

PA0281/124/001 		 Chlorpromazine hydrochloride  Manufacturing delays  Date of shortage:
End of February 2021

Expected return date:
End January 2022		 Last updated:
5th October 2021
 
HCP letter
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes 

PA0540/097/008
 Enoxaparin sodium  API unavailability   Date of shortage: 
22nd October 2021 

Expected return date: 
Unknown at present		 Last updated: 
13th October 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion

PA1457/001/001
 Amoxicillin & Clavulanic acid
 Manufacturing delays Date of shortage: 
13th October 2021 

Expected return date: 
Awaiting update		 Last updated: 
18th October 2021 
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion

PA1457/001/002		 Amoxicillin & clavalunic acid Unexpected increase in demand Date of shortage:
5th February 2020

Expected return date:
Awaiting update
 Last updated:
19th October 2021
CoAprovel 300mg/12.5mg Tablets

EU/1/98/086/004
 Irbesartan & Hydrochlorothiazide  Shipping delay  Date of shortage: 
5th November 2021

Expected return date: 
Late November 2021  		 Last updated: 
22nd October 2021 
Cyklokapron 100 mg/mL Solution for Injection/Infusion

PA0822/117/001
 Tranexamic acid Manufacturing delays Date of shortage: 
Week commencing 18th October 2021

Expected return date: 
Week commencing 15th November 2021 		 Last updated: 
5th October 2021 
Deslor 5mg Film Coated Tablets

PA0711/202/001
 Desloratidine Awaiting information   Date of shortage: 
19th September  2021  

Expected return date: 
Late December 2021		 Last updated: 
October 2021 
Desmopressin 100mcg/ml Nasal Drop Solution

PA1009/001/001 		 Desmopressin  Manufacturing delays due to quality issue

(multiple countries affected) 		 Date of shortage:
Mid December 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Dioralyte Blackcurrant Powder for Oral Solution (20 pack)

PA0540/098/001
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate  Unexpected increase in demand  Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021		 Last updated: 
30th September 2021
Dioralyte Citrus Powder for Oral Solution
(20 pack)

PA0540/098/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution
(6 pack)

PA0540/194/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Doxatan 4mg Tablets

PA0126/202/003 		 Doxazosin  Manufacturing delay   Date of shortage: 
4th October 2021

Expected return date:
Week commencing 1st November 2021		 Last updated: 
20th October 2021
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005		 Phenytoin Manufacturing delays

(multiple countries affected)		 Date of shortage:
Early November 2019

Expected return date:
Unknown at present		 Last updated:
4th June 2020
 
HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion

PA1852/002/001 		 Esomeprazole  Unavailability of API  Date of shortage:
Early October 2020

Expected return date:
Late November 2021		 Last updated:
12th October 2021
Ezetimibe Rowa 10mg Tablets

PA0074/074/001
 Ezetimibe Awaiting information  Date of shortage: 
19th October 2021 

Expected return date: 
Late November 2021 		 Last updated: 
21st October 2021
Ezetimibe Teva 10mg tablets

PA1986/012/001
 Ezetimibe  Quality Issue  Date of shortage: 
18th October 2021 

Expected return date: 
13th December 2021		 Last updated: 
4th October 2021
Ezetimibe 10mg tablets

PA0577/198/001
 Ezetimibe
 Manufacturing delays  Date of shortage: 
Late August 2021 

Expected return date: 
Early November 2021		 Last updated: 
4th October 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets

PA0711/262/001
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 22nd July 2021

Expected return date: 
October 2021		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date: 
End November 2021
 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets

PA1986/067/003
 Ezetimibe & simvastatin
 API unavailability

(multiple countries impacted) 		 Date of shortage: 
30th August 2021 

Expected return date: 
Awaiting update		 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets

PA0126/281/002
Ezetimibe & simvastatin
 Manufacturing delays   Date of shortage: 
Week commencing 20th September 2021

Expected return date: 
Unknown at present		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets

PA0126/281/004
 Ezetimibe & simvastatin
 Manufacturing delays Date of shortage: 
Week commencing 20th September 2021

Expected return date:  
Unknown at present		 Last updated: 
20th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection

PA0822/198/002
 Folinic Acid  Unexpected increase in demand Date of shortage: 
Week commencing 27th September 2021

Expected return date: 
Awaiting update		 Last updated:
18th October 2021
Fomicyt 40mg/ml Powder for Solution for Infusion

PA1972/001/001
 Fosfomycin sodium Regulatory issue  Date of Shortage: 
October 2021 

Expected return date: 
Unknown at present		 Last updated: 
12th October 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension

PA1142/014/001
 Gentamicin & Hydrocortisone Unavailability of API 

(multiple countries affected)		 Date of shortage: 
23rd August 2021

Expected return date:
Late November 2021		 Last updated: 
9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Imodium Plus 2mg/125mg Tablets

PA0330/050/001
 Loperamide & simeticone  Manufacturing delay  Date of shortage: 
11th October 2021 

Expected return date:
Week commencing 22nd November 2021		 Last updated: 
20th October 2021
Innohep 10,000 IU/ml Solution for Injection

PA0046/060/002
 Tinzaparin sodium
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
20th September 2021

Expected return date: 
Mid-November 2021
 Last updated: 
23rd September 2021
Instanyl 50mcg Nasal Spray 

EU/1/09/531/010-013
 Fentanyl  Quality issue 
(multiple countries affected)		 Date of shortage: 
1st August 2021 

Expected return date: 
February 2022
 Last updated: 
20th August 2021
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated: 
20th August 2021
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated:
20th August 2021
Invokana 300mg Film Coated Tablets

EU/1/13/884/005-008		 Canagliflozin
 Unexpected increase in demand  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021 		 Last updated: 
12th October 2021
Letrozole 2.5mg Film Coated Tablets

PA2315/109/001
 Letrozole  Awaiting information   Date of shortage: 
Week commencing 25th October 2021

Expected return date: 
End November 2021		 Last updated: 
18th October 2021 
Letrozole 2.5mg Film Coated Tablets

PA0126/198/001
 Letrozole  Manufacturing delays  Date of shortage: 
22nd October 2021 

Expected return date: 
22nd December 2021		 Last updated: 
18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets

PA0749/085/001
 Letrozole  API unavailability 

(multiple countries affected) 		 Date of shortage: 
Week commencing 9th August 2021

Expected return date: 
January 2021		 Last updated: 
5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet

PA0711/051/002 		 Lisinopril & Hydrochlorothiazide  Manufacturing delays  Date of shortage:
8th September 2020

Expected return date:
Week commencing 1st November 2021		 Last updated:
20th October 2021
Losartan 50mg Tablet 

PA2315/059/002 		 Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
Unknown at present 		 Last updated:
13th April 2021
Losartan 100mg Tablet

PA2315/059/003 		 Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film-Coated Tablets

PA0749/026/001
 Losartan & Hydrochlorothiazide
  Quality issue Date of shortage: Late October 2021  

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets

PA0749/026/002
 Losartan & Hydrochlorothiazide
 Quality issue  Date of shortage: 
Late October 2021

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
Unknown at present 
 Last updated: 
24th September  2021 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Metaraminol 10mg/ml Solution for Injection or Infusion 

PA22893/001/001		 Metaraminol  Awaiting update Date of shortage: 
Early April 2021 

Expected return date:
Awaiting update		 Last updated: 
30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution

PA23081/008/001
 Metformin  Regulatory Issue Date of shortage: 
13th August 2021

Expected return date: 
Unknown at present		 Last updated: 
10th August 2021
Mydrilate 1.0% w/v Eye Drops

PA22709/003/002
 Cyclopentolate Manufacturing delay  Date of shortage:
Early September 2021

Expected return date: 
Mid-October 2021		 Last updated: 
27th September 2021 
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion 

PA0073/111/002
 Naloxone Manufacturing delay  Date of shortage: 
18th October 2021

Expected return date: 
3rd December 2021 		 Last updated: 
19th October 2021
Nanocis 0.24mg Kit for Radiopharmaceutical Preparation

PA0677/006/001
 Rhenium sulphide
 Awaiting information  Date of shortage: 
Week commencing 20th September 2021 

Expected return date: 
Week commencing 8th November 2021		 Last updated: 
1st October 2021
Odrik 2mg Hard Capsule

PA2010/005/003
 Trandolapril
 Manufacturing delays Date of shortage: 
5th October 2021

Expected return date: 
Late October 2021 		 Last updated: 
28th September 2021
Oramox 125mg/5ml Powder for Oral Suspension

PA0298/019/001
 Amoxicillin
 Unexpected increase in demand  Date of shortage:
22nd October 2021 

Expected return date: 
Unknown at present 		 Last updated: 
19th October 2021 
OxyContin 5mg Prolonged Release Tablets 

PA1688/005/001
  Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021		 Last updated:
12th October 2021
OxyNorm Dispersa 5mg Orodispersible Tablets

PA1688/006/007
 Oxycodone  Unexpected increase in demand  Date of shortage: 
5th October 2021 

Expected return date: 
4th November 2021		 Last updated: 
18th October 2021
OxyNorm Dispersa 10mg Orodispersible Tablets

PA1688/006/008
 Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date:
Unknown at present 		  Last updated: 
12th October 2021
OxyNorm Dispersa 20mg Orodispersible Tablets

PA1688/006/009
 Oxycodone Manufacturing delays  Date of shortage: 
26th October 2021 

Expected return date:
February 2022		 Last updated: 
20th October 2021 
Palexia 4mg/ml Oral Solution

PA2242/012/010 		 Tapentadol hydrochloride  Quality issue

(multiple countries affected) 		 Date of shortage:
15th February 2021

Expected return date:
Unknown at present 		 Last updated: 
22nd February 2021
Paralief 500mg Tablets 

24 pack only

PA0126/020/001
 Paracetamol API unavailability  Date of shortage: 
Week commencing 23rd August 2021

Expected return date: 
27th October 2021
 Last updated: 
28th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w

PA0278/017/002
 Hydrocortisone & Lidocaine Hydrochloride  Manufacturing delays  Date of shortage:
February 2021

Expected return date:
January 2022		 Last updated: 
8th April 2021
Qlaira Film Coated Tablets

PA1410/058/001
  Estradiol API unavailability  Date of shortage: 
Mid November 2021

Expected return date: 
Q2 2022		 Last updated: 
7th October 2021

HCP letter
Questran 4g Powder for Oral Suspension

PA2239/005/001 		 Colestyramine  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2019

Expected return date:
January 2022		 Last updated:
30th March 2021 
Rifater 50mg/300mg/120mg Tablets

PA0822/143/002
 Isoniazid & Pyrazinamide & Rifampicin Quality issue

(multiple countries impacted)		 Date of shortage: 
23rd July 2021

Expected return date: 
26th October 2021		 Last updated:
18th October 2021

AMRIC guidance V3
Rosuvastatin 5mg Film Coated Tablets

PA2315/068/001
 Rosuvastatin Quality issue  Date of shortage:
27th August 2021

Expected return date: 
Q2 2022		  Last updated: 
30th August 2021
Rosuvastatin 10mg Film Coated Tablets

PA2315/068/002
 Rosuvastatin  Quality issue Date of shortage: 
27th August 2021 

Expected return date: 
Q2 2022 		 Last updated: 
30th August 2021 
Rosuvastatin 20mg Film Coated Tablets

PA2315/068/003
 Rosuvastatin   Distribution issue Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 		 Last updated: 
21st October 2021 
Rosuvastatin 40mg Film Coated Tablets

PA2315/068/004
 Rosuvastatin   Distribution issue
 Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
 Last updated: 
21st October 2021 
Sevelamer Carbonate 800mg Film Coated Tablets

PA0577/205/001
 Sevelamer  Manufacturing delays Date of shortage: 
Late October

Expected return date: 
Unknown at present  		 Last updated: 
22nd October 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Mid-December 2021		 Last updated:
22nd October 2021
Stesolid Rectal Solution 5mg

PA2315/137/001
 Diazepam  Manufacturing delays Date of shortage: 
Late August 2021

Expected return date: 
November 2021		 Last updated: 
12th August 2021
Stesolid Rectal Solution 10mg

PA2315/137/002
  Diazepam Manufacturing delays  Date of shortage: 
Week commencing 19th July 2021. 

Expected return date: 
November 2021		 Last updated: 
21st July 2021
Targin 20mg/10mg Prolonged Release Tablets

PA1688/010/001		 Oxycodone & Naloxone  Shipping delays Date of shortage: 
27th September 2021 

Expected return date: 
28th October 2021
 Last updated: 
22nd October 2021
Telmisartan Rowa 40mg Tablets

PA0074/078/002
 Telmisartan  Unexpected increase in demand  Date of shortage: 
7th September 2021

Expected return date: 
Late November 2021		  Last updated: 
20th October 2021
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
 Alendronic acid API unavailability  Date of shortage: 
6th September 2021 

Expected return date: 
Late November 2021 		 Last updated: 
23rd August 2021 
Tracrium 10 mg/ml, Solution for injection or infusion

(25ml ampoule)

PA1691/029/002
 Atracurium  Unexpected increase in demand Date of shortage: 
24th September 2021 

Expected return date: 
20th November 2021 		 Last updated: 
24th September 2021
Trandate 200mg Film Coated Tablet

PA1638/006/003 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
End October 2021		 Last updated:
11th October 2021
TPN – various B. Braun products
 Various  Manufacturing delays  Date of shortage: 
4th October 2021

Expected return date: 
Unknown at present		 Last updated: 
5th October 2021

HCP letter
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment

PA22650/004/001
 Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride  Regulatory issue Date of shortage: 
Late September 2021

Expected return date: 
Late December 2021
 Last updated: 
15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets

PA1688/011/001
Product name Active ingredient Reason for shortage Date of shortage
 Additional information
Abstral 100mcg Sublingual Tablets

PA2288/004/002
  Fentanyl  Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
3rd September 2021 

Expected return date: 
Week commencing 1st October 2021		 Last updated: 
22nd October 2021
Abstral 200mcg Sublingual Tablets

PA2288/004/003
 Fentanyl Manufacturing delays 

(multiple countries affected)		 Date of shortage:
15th August 2021

Return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 300mcg Sublingual Tablets

PA2288/004/004
 Fentanyl  Manufacturing delays 

(multiple countries affected) 		 Date of shortage: 
5th October 2021

Expected return date: 
Week commencing 25th October 2021
 Last updated: 
22nd October 2021
Abstral 400mcg Sublingual Tablets

PA2288/004/005
 Fentanyl  Manufacturing delays 

(multiple countries affected)
 Date of shortage: 
4th October 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Abstral 600mcg Sublingual Tablets

PA2288/004/006
 Fentanyl   Manufacturing delay 

(multiple countries affected)		 Date of shortage: 
2nd September 2021 

Expected return date: 
Week commencing 25th October 2021		 Last updated: 
22nd October 2021
Abstral 700mcg Sublingual Tablets

PA2288/004/007
 Fentanyl Manufacturing delay 

(multiple countries affected) 		 Date of shortage: 
2nd September 2021

Expected return date: 
Early December 2021		 Last updated: 
22nd October 2021
Adizem-XL 180mg Prolonged Release Capsules

PA1688/001/005
 Dilitazem  Manufacturing delays Date of shortage: 
1st October 2021

Expected return date: 
November 2021 		 Last updated: 
27th September 2021
Amitriptyline 25mg Film Coated Tablets

PA0126/041/001
 Amitriptyline
 API unavailability Date of shortage: 
2nd September 2021 

Expected return date: 
Late October 2021		 Last updated: 
7th September 2021 

HCP letter
Astilin 10mg Tablets

PA23163/001/001
 Amitriptyline  Awaiting update Date of shortage: 
27th August 2021

Expected return date: 
29th October 2021		 Last updated: 
5th October 2021

HCP letter
Ativan 4mg/ml Solution for Injection

PA0822/090/002 		 Lorazepam  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Early August 2020

Expected return date:
Unknown at present		 Last updated:
14th May 2021 
 
HCP letter
BCG-Medac Powder and Solvent for Suspension for Intravesical Use

PA0623/004/001 		 Bacillus Calmette Guerin bacteria  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
1st October 2019

Expected return date:
2022		 Last updated:
3rd February 2021
Bendroflumethiazide 2.5mg Tablets

PA22749/021/001
 Bendroflumethiazide
  Regulatory issue Date of shortage:
3rd September 2021

Expected return date: 
Awaiting update		 Last updated: 
1st October 2021
Beromun 1mg Powder for Solution for Infusion

EU/1/99/097/001 		 Tasonermin  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
December 2020

Expected return date:
November 2021		 Last updated:
1st June 2021
Calcium Acetate 500mg Tablets

PA0281/063/001
 Calcium Acetate API unavailability  Date of shortage: 
Week commencing 26th July 2021

Expected return date: 
Late December 2021		 Last updated: 
30th September 2021
Canesten HC 1% w/w + 1% w/w Cream

PA1410/040/002
 Clotrimazole & Hydrocortisone  Manufacturing delays Date of shortage: 
30th September 2021 

Expected return date:
5th November 2021		 Last updated: 
22nd September 2021
Catapres Tablets 100mcg

PA2256/003/001
  Clonidine Manufacturing delays

(multiple countries affected)		 Date of shortage: 
25th July 2021

Expected return date: 
25th October 2021		 Last updated: 
21st June 2021 
Champix 0.5mg Film Coated Tablet

EU/1/06/360/001
 Varenicline 
 Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 2021 

Expected return date: 
Unknown at present 		 Last updated:
18th June 2021

HCP letter
Champix 1mg Film Coated Tablet

EU/1/06/360/005
 Varenicline Quality issue

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Champix 0.5 mg + 1 mg Film Coated Tablet

EU/1/06/360/003
 Varenicline 
 Quality issue 

(multiple countries affected)		 Date of shortage: 
Week commencing 21st June 

Expected return date: 
Unknown at present 		 Last updated: 
18th June 2021

HCP letter
Chlorhexidine Acetate 0.015% w/v and Cetrimide 0.15% w/v Irrigation Solution

PA2299/005/001
 Chlorhexidine acetate & cetrimide
 Unexpected increase in demand Date of shortage: 
September 2021 

Expected return date: 
Mid November 2021 		 Last updated: 
20th October 2021
Chlorpromazine Elixir BP 25mg/5ml Oral Solution

PA0281/124/001 		 Chlorpromazine hydrochloride  Manufacturing delays  Date of shortage:
End of February 2021

Expected return date:
End January 2022		 Last updated:
5th October 2021
 
HCP letter
Clexane Forte 12,000 IU (120mg) /0.8ml Solution for Injection in Pre Filled Syringes 

PA0540/097/008
 Enoxaparin sodium  API unavailability   Date of shortage: 
22nd October 2021 

Expected return date: 
Unknown at present		 Last updated: 
13th October 2021
Co-Amoxiclav 500mg/100mg Powder for Solution for Injection/Infusion

PA1457/001/001
 Amoxicillin & Clavulanic acid
 Manufacturing delays Date of shortage: 
13th October 2021 

Expected return date: 
Awaiting update		 Last updated: 
18th October 2021 
Co-Amoxiclav 1000mg/200mg Powder for Solution for Injection/Infusion

PA1457/001/002		 Amoxicillin & clavalunic acid Unexpected increase in demand Date of shortage:
5th February 2020

Expected return date:
Awaiting update
 Last updated:
19th October 2021
CoAprovel 300mg/12.5mg Tablets

EU/1/98/086/004
 Irbesartan & Hydrochlorothiazide  Shipping delay  Date of shortage: 
5th November 2021

Expected return date: 
Late November 2021  		 Last updated: 
22nd October 2021 
Cyklokapron 100 mg/mL Solution for Injection/Infusion

PA0822/117/001
 Tranexamic acid Manufacturing delays Date of shortage: 
Week commencing 18th October 2021

Expected return date: 
Week commencing 15th November 2021 		 Last updated: 
5th October 2021 
Deslor 5mg Film Coated Tablets

PA0711/202/001
 Desloratidine Awaiting information   Date of shortage: 
19th September  2021  

Expected return date: 
Late December 2021		 Last updated: 
October 2021 
Desmopressin 100mcg/ml Nasal Drop Solution

PA1009/001/001 		 Desmopressin  Manufacturing delays due to quality issue

(multiple countries affected) 		 Date of shortage:
Mid December 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Desmospray Desmopressin Nasal Spray

PA1009/005/001 		 Desmopressin  Quality issue

(multiple countries affected) 		 Date of shortage:
22nd July 2020

Expected return date:
2022 		 Last updated:
11th December 2020 
Diazemuls 5mg/ml Emulsion for Injection

PA2315/098/001 		 Diazepam  Manufacturing delays  Date of shortage:
Mid February 2020

Expected return date:
Unknown at present		 Last updated:
30th March 2021 
Dioralyte Blackcurrant Powder for Oral Solution (20 pack)

PA0540/098/001
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate  Unexpected increase in demand  Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021		 Last updated: 
30th September 2021
Dioralyte Citrus Powder for Oral Solution
(20 pack)

PA0540/098/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Dioralyte Rebalance Citrus Powder for Oral Solution
(6 pack)

PA0540/194/002
 Sodium chloride, potassium chloride, glucose, disodium hydrogen citrate
 Unexpected increase in demand Date of shortage: 
17th September 2021

Expected return date: 
1st November 2021
 Last updated: 
30th September 2021
Doxatan 4mg Tablets

PA0126/202/003 		 Doxazosin  Manufacturing delay   Date of shortage: 
4th October 2021

Expected return date:
Week commencing 1st November 2021		 Last updated: 
20th October 2021
Emerade 150mcg Solution in a Pre-Filled Pen

PA1696/009/001 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 300mcg Solution in a Pre-Filled Pen

PA1696/009/002 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Emerade 500mcg Solution in a Pre-Filled Pen

PA1696/009/003 		 Adrenaline  Quality issue

(multiple countries affected) 		 Date of shortage:
30th September 2019

Expected return date:
Unknown at present 		 Last updated:
18th December 2020

Alternatives are available 
Epanutin Infatabs 50mg Chewable Tablets

PA0822/011/005		 Phenytoin Manufacturing delays

(multiple countries affected)		 Date of shortage:
Early November 2019

Expected return date:
Unknown at present		 Last updated:
4th June 2020
 
HCP Letter
Esomeprazole Ticerin 40mg Powder for Solution for Injection of Infusion

PA1852/002/001 		 Esomeprazole  Unavailability of API  Date of shortage:
Early October 2020

Expected return date:
Late November 2021		 Last updated:
12th October 2021
Ezetimibe Rowa 10mg Tablets

PA0074/074/001
 Ezetimibe Awaiting information  Date of shortage: 
19th October 2021 

Expected return date: 
Late November 2021 		 Last updated: 
21st October 2021
Ezetimibe Teva 10mg tablets

PA1986/012/001
 Ezetimibe  Quality Issue  Date of shortage: 
18th October 2021 

Expected return date: 
13th December 2021		 Last updated: 
4th October 2021
Ezetimibe 10mg tablets

PA0577/198/001
 Ezetimibe
 Manufacturing delays  Date of shortage: 
Late August 2021 

Expected return date: 
Early November 2021		 Last updated: 
4th October 2021
Ezetimibe/Simvastatin Rowex 10mg/20mg Tablets

PA0711/262/001
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 22nd July 2021

Expected return date: 
October 2021		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Rowex 10mg/80mg Tablets

PA0711/262/003
 Ezetimibe & simvastatin
 Manufacturing delays  Date of shortage: 
22nd July 2021

Expected return date: 
End November 2021
 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Teva Pharma 10mg/80mg Tablets

PA1986/067/003
 Ezetimibe & simvastatin
 API unavailability

(multiple countries impacted) 		 Date of shortage: 
30th August 2021 

Expected return date: 
Awaiting update		 Last updated: 
20th October 2021 
Ezetimibe/Simvastatin Clonmel 10mg/20mg Tablets

PA0126/281/002
Ezetimibe & simvastatin
 Manufacturing delays   Date of shortage: 
Week commencing 20th September 2021

Expected return date: 
Unknown at present		 Last updated: 
20th September 2021
Ezetimibe/Simvastatin Clonmel 10mg/80mg Tablets

PA0126/281/004
 Ezetimibe & simvastatin
 Manufacturing delays Date of shortage: 
Week commencing 20th September 2021

Expected return date:  
Unknown at present		 Last updated: 
20th September 2021
Folinic Acid (as Calcium Folinate) 7.5mg/ml Solution for Injection

PA0822/198/002
 Folinic Acid  Unexpected increase in demand Date of shortage: 
Week commencing 27th September 2021

Expected return date: 
Awaiting update		 Last updated:
18th October 2021
Fomicyt 40mg/ml Powder for Solution for Infusion

PA1972/001/001
 Fosfomycin sodium Regulatory issue  Date of Shortage: 
October 2021 

Expected return date: 
Unknown at present		 Last updated: 
12th October 2021
Gentisone HC 0.3% w/v & 1.0% w/v Ear Drops, Suspension

PA1142/014/001
 Gentamicin & Hydrocortisone Unavailability of API 

(multiple countries affected)		 Date of shortage: 
23rd August 2021

Expected return date:
Late November 2021		 Last updated: 
9th August 2021
Hydromorphone 20mg/ml Solution for Injection/Infusion

PA0549/030/001 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Hydromorphone 50mg/ml Solution for Injection/Infusion

PA0549/030/002 		 Hydromorphone  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid August 2020

Expected return date:
February 2022		 Last updated:
18th October 2021
Imodium Plus 2mg/125mg Tablets

PA0330/050/001
 Loperamide & simeticone  Manufacturing delay  Date of shortage: 
11th October 2021 

Expected return date:
Week commencing 22nd November 2021		 Last updated: 
20th October 2021
Innohep 10,000 IU/ml Solution for Injection

PA0046/060/002
 Tinzaparin sodium
 Unexpected increase in demand

(multiple countries affected)		 Date of shortage: 
20th September 2021

Expected return date: 
Mid-November 2021
 Last updated: 
23rd September 2021
Instanyl 50mcg Nasal Spray 

EU/1/09/531/010-013
 Fentanyl  Quality issue 
(multiple countries affected)		 Date of shortage: 
1st August 2021 

Expected return date: 
February 2022
 Last updated: 
20th August 2021
Instanyl 100mcg Nasal Spray 

EU/1/09/531/014-017
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated: 
20th August 2021
Instanyl 200mcg Nasal Spray

EU/1/09/531/018-021
 Fentanyl  Quality issue

(multiple countries affected) 		 Date of shortage: 
2nd April 2021

Expected return date: 
February 2022		 Last updated:
20th August 2021
Invokana 300mg Film Coated Tablets

EU/1/13/884/005-008		 Canagliflozin
 Unexpected increase in demand  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021 		 Last updated: 
12th October 2021
Letrozole 2.5mg Film Coated Tablets

PA2315/109/001
 Letrozole  Awaiting information   Date of shortage: 
Week commencing 25th October 2021

Expected return date: 
End November 2021		 Last updated: 
18th October 2021 
Letrozole 2.5mg Film Coated Tablets

PA0126/198/001
 Letrozole  Manufacturing delays  Date of shortage: 
22nd October 2021 

Expected return date: 
22nd December 2021		 Last updated: 
18th October 2021
Letrozole Teva 2.5 mg Film Coated Tablets

PA0749/085/001
 Letrozole  API unavailability 

(multiple countries affected) 		 Date of shortage: 
Week commencing 9th August 2021

Expected return date: 
January 2021		 Last updated: 
5th October 2021
Lispril Hydrochlorothiazide 20mg/12.5mg Tablet

PA0711/051/002 		 Lisinopril & Hydrochlorothiazide  Manufacturing delays  Date of shortage:
8th September 2020

Expected return date:
Week commencing 1st November 2021		 Last updated:
20th October 2021
Losartan 50mg Tablet 

PA2315/059/002 		 Losartan  Manufacturing delays  Date of shortage:
25th September 2019

Expected return date:
Unknown at present 		 Last updated:
13th April 2021
Losartan 100mg Tablet

PA2315/059/003 		 Losartan  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Unknown at present		 Last updated:
13th April 2021
Losartan/Hydrochlorothiazide Teva 50mg/12.5mg Film-Coated Tablets

PA0749/026/001
 Losartan & Hydrochlorothiazide
  Quality issue Date of shortage: Late October 2021  

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Losartan/Hydrochlorothiazide Teva 100mg/25mg Film-Coated Tablets

PA0749/026/002
 Losartan & Hydrochlorothiazide
 Quality issue  Date of shortage: 
Late October 2021

Expected return date: 
March 2022		 Last updated: 
22nd October 2021
Marcain 0.5% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for Injection

PA1691/025/002
 Bupivacaine & adrenaline Manufacturing delay

(multiple countries affected) 		 Date of shortage: 
1st July 2021

Expected return date: 
Unknown at present 
 Last updated: 
24th September  2021 
Mefac 250mg Capsule

PA0074/015/001 		 Mefenamic acid  Manufacturing delays  Date of shortage:
End of June 2019

Expected return date:
Unknown at present		 Last updated:
23rd April 2021
 
Metaraminol 10mg/ml Solution for Injection or Infusion 

PA22893/001/001		 Metaraminol  Awaiting update Date of shortage: 
Early April 2021 

Expected return date:
Awaiting update		 Last updated: 
30th June 2021
Metformin Hydrochloride 500mg/5ml Oral Solution

PA23081/008/001
 Metformin  Regulatory Issue Date of shortage: 
13th August 2021

Expected return date: 
Unknown at present		 Last updated: 
10th August 2021
Mydrilate 1.0% w/v Eye Drops

PA22709/003/002
 Cyclopentolate Manufacturing delay  Date of shortage:
Early September 2021

Expected return date: 
Mid-October 2021		 Last updated: 
27th September 2021 
Naloxone Hydrochloride 400mcg/ml Solution for Injection or Infusion 

PA0073/111/002
 Naloxone Manufacturing delay  Date of shortage: 
18th October 2021

Expected return date: 
3rd December 2021 		 Last updated: 
19th October 2021
Nanocis 0.24mg Kit for Radiopharmaceutical Preparation

PA0677/006/001
 Rhenium sulphide
 Awaiting information  Date of shortage: 
Week commencing 20th September 2021 

Expected return date: 
Week commencing 8th November 2021		 Last updated: 
1st October 2021
Odrik 2mg Hard Capsule

PA2010/005/003
 Trandolapril
 Manufacturing delays Date of shortage: 
5th October 2021

Expected return date: 
Late October 2021 		 Last updated: 
28th September 2021
Oramox 125mg/5ml Powder for Oral Suspension

PA0298/019/001
 Amoxicillin
 Unexpected increase in demand  Date of shortage:
22nd October 2021 

Expected return date: 
Unknown at present 		 Last updated: 
19th October 2021 
OxyContin 5mg Prolonged Release Tablets 

PA1688/005/001
  Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date: 
Early November 2021		 Last updated:
12th October 2021
OxyNorm Dispersa 5mg Orodispersible Tablets

PA1688/006/007
 Oxycodone  Unexpected increase in demand  Date of shortage: 
5th October 2021 

Expected return date: 
4th November 2021		 Last updated: 
18th October 2021
OxyNorm Dispersa 10mg Orodispersible Tablets

PA1688/006/008
 Oxycodone Manufacturing delays  Date of shortage: 
18th October 2021

Expected return date:
Unknown at present 		  Last updated: 
12th October 2021
OxyNorm Dispersa 20mg Orodispersible Tablets

PA1688/006/009
 Oxycodone Manufacturing delays  Date of shortage: 
26th October 2021 

Expected return date:
February 2022		 Last updated: 
20th October 2021 
Palexia 4mg/ml Oral Solution

PA2242/012/010 		 Tapentadol hydrochloride  Quality issue

(multiple countries affected) 		 Date of shortage:
15th February 2021

Expected return date:
Unknown at present 		 Last updated: 
22nd February 2021
Paralief 500mg Tablets 

24 pack only

PA0126/020/001
 Paracetamol API unavailability  Date of shortage: 
Week commencing 23rd August 2021

Expected return date: 
27th October 2021
 Last updated: 
28th August 2021
Perinal Cutaneous Spray hydrocortisone 0.2% w/w / lidocaine hydrochloride monohydrate 1.0% w/w

PA0278/017/002
 Hydrocortisone & Lidocaine Hydrochloride  Manufacturing delays  Date of shortage:
February 2021

Expected return date:
January 2022		 Last updated: 
8th April 2021
Qlaira Film Coated Tablets

PA1410/058/001
  Estradiol API unavailability  Date of shortage: 
Mid November 2021

Expected return date: 
Q2 2022		 Last updated: 
7th October 2021

HCP letter
Questran 4g Powder for Oral Suspension

PA2239/005/001 		 Colestyramine  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
Mid June 2019

Expected return date:
January 2022		 Last updated:
30th March 2021 
Rifater 50mg/300mg/120mg Tablets

PA0822/143/002
 Isoniazid & Pyrazinamide & Rifampicin Quality issue

(multiple countries impacted)		 Date of shortage: 
23rd July 2021

Expected return date: 
26th October 2021		 Last updated:
18th October 2021

AMRIC guidance V3
Rosuvastatin 5mg Film Coated Tablets

PA2315/068/001
 Rosuvastatin Quality issue  Date of shortage:
27th August 2021

Expected return date: 
Q2 2022		  Last updated: 
30th August 2021
Rosuvastatin 10mg Film Coated Tablets

PA2315/068/002
 Rosuvastatin  Quality issue Date of shortage: 
27th August 2021 

Expected return date: 
Q2 2022 		 Last updated: 
30th August 2021 
Rosuvastatin 20mg Film Coated Tablets

PA2315/068/003
 Rosuvastatin   Distribution issue Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 		 Last updated: 
21st October 2021 
Rosuvastatin 40mg Film Coated Tablets

PA2315/068/004
 Rosuvastatin   Distribution issue
 Date of shortage: 
18th October 2021 

Expected return date: 
Early January 2022 
 Last updated: 
21st October 2021 
Sevelamer Carbonate 800mg Film Coated Tablets

PA0577/205/001
 Sevelamer  Manufacturing delays Date of shortage: 
Late October

Expected return date: 
Unknown at present  		 Last updated: 
22nd October 2021
Sprilon 12.5% Zinc Oxide & 1.04% Dimethicone Cutaneous Spray Suspension

PA22906/001/001 		 Zinc oxide & Dimethicone  Manufacturing delays  Date of shortage:
October 2019

Expected return date:
Mid-December 2021		 Last updated:
22nd October 2021
Stesolid Rectal Solution 5mg

PA2315/137/001
 Diazepam  Manufacturing delays Date of shortage: 
Late August 2021

Expected return date: 
November 2021		 Last updated: 
12th August 2021
Stesolid Rectal Solution 10mg

PA2315/137/002
  Diazepam Manufacturing delays  Date of shortage: 
Week commencing 19th July 2021. 

Expected return date: 
November 2021		 Last updated: 
21st July 2021
Targin 20mg/10mg Prolonged Release Tablets

PA1688/010/001		 Oxycodone & Naloxone  Shipping delays Date of shortage: 
27th September 2021 

Expected return date: 
28th October 2021
 Last updated: 
22nd October 2021
Telmisartan Rowa 40mg Tablets

PA0074/078/002
 Telmisartan  Unexpected increase in demand  Date of shortage: 
7th September 2021

Expected return date: 
Late November 2021		  Last updated: 
20th October 2021
Tevanate Once Weekly 70mg Tablets

PA0749/016/001
 Alendronic acid API unavailability  Date of shortage: 
6th September 2021 

Expected return date: 
Late November 2021 		 Last updated: 
23rd August 2021 
Tracrium 10 mg/ml, Solution for injection or infusion

(25ml ampoule)

PA1691/029/002
 Atracurium  Unexpected increase in demand Date of shortage: 
24th September 2021 

Expected return date: 
20th November 2021 		 Last updated: 
24th September 2021
Trandate 200mg Film Coated Tablet

PA1638/006/003 		 Labetalol hydrochloride  Manufacturing delays

(multiple countries affected) 		 Date of shortage:
July 2019

Expected return date:
End October 2021		 Last updated:
11th October 2021
TPN – various B. Braun products
 Various  Manufacturing delays  Date of shortage: 
4th October 2021

Expected return date: 
Unknown at present		 Last updated: 
5th October 2021

HCP letter
Ultraproct 0.92mg/ + 0.95mg/g + 5mg/g Rectal Ointment

PA22650/004/001
 Fluocortolone Pivalate; Fluocortolone caproate; Cinchocaine hydrochloride  Regulatory issue Date of shortage: 
Late September 2021

Expected return date: 
Late December 2021
 Last updated: 
15th September 2021
Uniphyllin Continus 200mg Prolonged Release Tablets

PA1688/011/001

Date of shortage: 
20th October 2021 

Expected return date: 
Unknown at present

Anapen 300 micrograms in 0.3ml solution for injection in a pre-filled syringe


Contact us:

Medicinal Product Shortages Unit
Health Products Regulatory Authority 
Kevin O’Malley House
Earlsfort Terrace,
Dublin 2
Tel: +353 1 676 4971
Fax: +353 1 676 7836
shortages@hpra.ie